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Aerobic organisms actively control oxygen supplies and have evolved di.pdf

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amolawachat

This document discusses mechanisms of oxygen delivery and adaptive responses to low oxygen levels in aerobic organisms. It asks about at least two mechanisms controlling hemoglobin oxygen delivery efficiency, mechanisms regulating hypoxia-inducible factor 1, and experimental evidence that oxygen deficiency leads to adaptive changes in mammalian nutrient metabolism and energy generation.

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Aerobic organisms actively control oxygen supplies and have evolved diverse systems to adapt to oxygen limitation. 1. What are known mechanisms (at least two) controlling the efficiency of hemoglobin-mediated oxygen delivery? 2. What're the mechanisms underlying the regulation of hypoxia-inducible factor-1 (HIF-1)? 3. Describe two or more experimental evidence and rationale supporting the argument that oxygen deficiency leads to adaptive responses in nutrient metabolism and energy generation in mammals.

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