SlideShare a Scribd company logo
CONFIDENTIAL © 2019 AyurData
Balance
Calmness
Serenity
Introducing
Advanced Statistical Manual
for Ayurveda Research
Kadiroo Jayaraman
Praveen Venugopal
AyurData
© 2019 AyurData /CONFIDENTIAL 2
The basic manual
covered the syllabus
specified for M.D.
students on Medical
Statistics, by the Central
Council of Indian
Medicine.
Earlier Release
© 2019 AyurData /CONFIDENTIAL 3
In the advanced manual, we
have covered more
advanced statistical
applications including that in
data science.
The mode of presentation is
that the concept is
introduced first, followed by
illustration and the use in a
real context.
Some mathematics will be
involved but well explained
in the text.
Current Release
© 2019 AyurData /CONFIDENTIAL 4
TOPICS COVERED
1.Analysis of Repeated Measures
2.Multiple Linear Regression
3.Superiority, Bioequivalence and Non-inferiority trials
4.Logistic Regression
5.Decision Trees
6.Random Forest
7.Support Vector Machines
8.Naïve Bayes Classifier
9.Neural Networks
10.K-Nearest Neighbour Technique
11.Principal Component Analysis
12.Cluster Analysis
13.Stratified Multistage Sampling
14.Analysis of Time Series Data
15.Analysis of Time-to-event Data
© 2019 AyurData /CONFIDENTIAL 5
ANALYSIS OF REPEATED MEASURES
Repeated measurements is a common case in Ayurveda experiments.
Repeated measurements on the same individual would be correlated and
so require special analysis.
© 2019 AyurData /CONFIDENTIAL 6
ANALYSIS OF REPEATED MEASURES
ANOVA table for two-way with repeated measures for one factor
For instance, Factor A could be treatment and B could be age group provided
the patients have been stratified based on age group. In case age was a taken
as a baseline variable that is continuous, it can be included as a covariate in the
model. The computations and interpretations are well-explained in the manual.
© 2019 AyurData /CONFIDENTIAL 7
MULTIPLE LINEAR REGRESSION
The model we are covering is,
which in the matrix form would be,
The model fitting, testing and residual analysis are illustrated using
a real-life dataset.
© 2019 AyurData /CONFIDENTIAL 8
Superiority, Bioequivalence and Non-inferiority trials
In many practical situations, we encounter the following types of
comparisons:
• The new drug is better than the standard drug.
• The new drug is equivalent to the standard drug.
• The new drug is at least as good as the standard drug.
The hypothesis and test criterion to be employed in each of the above
cases have to be different. For instance,
Superiority hypothesis
H0: ∆ = 0
H1: ∆ ≠ 0, or (∆ > 0, or ∆ <0 for one-tailed tests)
© 2019 AyurData /CONFIDENTIAL 9
Superiority, Bioequivalence and Non-inferiority trials
Bio-equivalence hypothesis
H0: ∆ > ∆E or ∆ < -∆E
H1: ∆E ≤ ∆ ≤ ∆E where ∆E is a clinically relevant equivalence
margin (usually 10%).
Non-inferiority hypothesis
H0: ∆ ≤-∆NI
H1: ∆ >-∆NI where ∆NI is a clinically relevant non-inferiority margin
(usually 10%).
The tests involved and the interpretation are illustrated using
examples from Ayurveda.
© 2019 AyurData /CONFIDENTIAL 10
THANK YOU
© 2019 AyurData /CONFIDENTIAL 10
AyurData Team
Website: http://ayurdata.in/#service-content
Facebook: https://www.facebook.com/AyurData/

More Related Content

Similar to Advanced statistical manual part i

Advanced Statistical Manual for Ayurveda Research
Advanced Statistical Manual for Ayurveda ResearchAdvanced Statistical Manual for Ayurveda Research
Advanced Statistical Manual for Ayurveda Research
Ayurdata
 
Advanced statistical manual part ii
Advanced statistical manual part iiAdvanced statistical manual part ii
Advanced statistical manual part ii
Ayurdata
 
Stat Methods in ayurveda
Stat Methods in ayurvedaStat Methods in ayurveda
Stat Methods in ayurveda
Ayurdata
 
Ich sample size
Ich sample sizeIch sample size
Ich sample size
Ayurdata
 
Cost Effectiveness Analysis in Health economics
Cost Effectiveness Analysis in Health economicsCost Effectiveness Analysis in Health economics
Cost Effectiveness Analysis in Health economics
Gerardo García
 
Advanced manual part 4
Advanced manual part 4Advanced manual part 4
Advanced manual part 4
Ayurdata
 
Advanced Statistical Manual Part III
Advanced Statistical Manual Part IIIAdvanced Statistical Manual Part III
Advanced Statistical Manual Part III
Ayurdata
 
Assigning Scores For Ordered Categorical Responses
Assigning Scores For Ordered Categorical ResponsesAssigning Scores For Ordered Categorical Responses
Assigning Scores For Ordered Categorical Responses
Mary Montoya
 
Ayur data startup
Ayur data startupAyur data startup
Ayur data startup
Ayurdata
 
Value based care.
Value based care.Value based care.
Value based care.
Ahimanikya Satapathy
 
2012 NATIONAL NURSING CORE COMPETENCY STANDARDS
2012 NATIONAL NURSING CORE COMPETENCY STANDARDS2012 NATIONAL NURSING CORE COMPETENCY STANDARDS
2012 NATIONAL NURSING CORE COMPETENCY STANDARDS
Hanna Olvido
 
Services for Later Life: Are we any closer to integrating health and social c...
Services for Later Life: Are we any closer to integrating health and social c...Services for Later Life: Are we any closer to integrating health and social c...
Services for Later Life: Are we any closer to integrating health and social c...
Age UK
 
Effective Useful Life and Persistence for Behavioral Programs and Framing the...
Effective Useful Life and Persistence for Behavioral Programs and Framing the...Effective Useful Life and Persistence for Behavioral Programs and Framing the...
Effective Useful Life and Persistence for Behavioral Programs and Framing the...
Opinion Dynamics
 
cost.pdffeujjfufwrffjufjohfurubbjgkkfjbjfbeo
cost.pdffeujjfufwrffjufjohfurubbjgkkfjbjfbeocost.pdffeujjfufwrffjufjohfurubbjgkkfjbjfbeo
cost.pdffeujjfufwrffjufjohfurubbjgkkfjbjfbeo
interaman123
 
Ich guidelines e9 to e12
Ich guidelines e9 to e12Ich guidelines e9 to e12
Ich guidelines e9 to e12
Khushboo Bhatia
 
Note 3-CEA, CBA, CUA.pptxefhejbvbvskjvbfcbb
Note 3-CEA, CBA, CUA.pptxefhejbvbvskjvbfcbbNote 3-CEA, CBA, CUA.pptxefhejbvbvskjvbfcbb
Note 3-CEA, CBA, CUA.pptxefhejbvbvskjvbfcbb
interaman123
 
Chapter 019
Chapter 019Chapter 019
Chapter 019
stanbridge
 
Ebm misconception myths facts
Ebm misconception myths factsEbm misconception myths facts
Ebm misconception myths facts
Aboubakr Elnashar
 
Application of EQ-5D in Reimbursement Decision Making: The Case of NICE
Application of EQ-5D in Reimbursement Decision Making: The Case of NICEApplication of EQ-5D in Reimbursement Decision Making: The Case of NICE
Application of EQ-5D in Reimbursement Decision Making: The Case of NICE
Office of Health Economics
 
How to establish and evaluate clinical prediction models - Statswork
How to establish and evaluate clinical prediction models - StatsworkHow to establish and evaluate clinical prediction models - Statswork
How to establish and evaluate clinical prediction models - Statswork
Stats Statswork
 

Similar to Advanced statistical manual part i (20)

Advanced Statistical Manual for Ayurveda Research
Advanced Statistical Manual for Ayurveda ResearchAdvanced Statistical Manual for Ayurveda Research
Advanced Statistical Manual for Ayurveda Research
 
Advanced statistical manual part ii
Advanced statistical manual part iiAdvanced statistical manual part ii
Advanced statistical manual part ii
 
Stat Methods in ayurveda
Stat Methods in ayurvedaStat Methods in ayurveda
Stat Methods in ayurveda
 
Ich sample size
Ich sample sizeIch sample size
Ich sample size
 
Cost Effectiveness Analysis in Health economics
Cost Effectiveness Analysis in Health economicsCost Effectiveness Analysis in Health economics
Cost Effectiveness Analysis in Health economics
 
Advanced manual part 4
Advanced manual part 4Advanced manual part 4
Advanced manual part 4
 
Advanced Statistical Manual Part III
Advanced Statistical Manual Part IIIAdvanced Statistical Manual Part III
Advanced Statistical Manual Part III
 
Assigning Scores For Ordered Categorical Responses
Assigning Scores For Ordered Categorical ResponsesAssigning Scores For Ordered Categorical Responses
Assigning Scores For Ordered Categorical Responses
 
Ayur data startup
Ayur data startupAyur data startup
Ayur data startup
 
Value based care.
Value based care.Value based care.
Value based care.
 
2012 NATIONAL NURSING CORE COMPETENCY STANDARDS
2012 NATIONAL NURSING CORE COMPETENCY STANDARDS2012 NATIONAL NURSING CORE COMPETENCY STANDARDS
2012 NATIONAL NURSING CORE COMPETENCY STANDARDS
 
Services for Later Life: Are we any closer to integrating health and social c...
Services for Later Life: Are we any closer to integrating health and social c...Services for Later Life: Are we any closer to integrating health and social c...
Services for Later Life: Are we any closer to integrating health and social c...
 
Effective Useful Life and Persistence for Behavioral Programs and Framing the...
Effective Useful Life and Persistence for Behavioral Programs and Framing the...Effective Useful Life and Persistence for Behavioral Programs and Framing the...
Effective Useful Life and Persistence for Behavioral Programs and Framing the...
 
cost.pdffeujjfufwrffjufjohfurubbjgkkfjbjfbeo
cost.pdffeujjfufwrffjufjohfurubbjgkkfjbjfbeocost.pdffeujjfufwrffjufjohfurubbjgkkfjbjfbeo
cost.pdffeujjfufwrffjufjohfurubbjgkkfjbjfbeo
 
Ich guidelines e9 to e12
Ich guidelines e9 to e12Ich guidelines e9 to e12
Ich guidelines e9 to e12
 
Note 3-CEA, CBA, CUA.pptxefhejbvbvskjvbfcbb
Note 3-CEA, CBA, CUA.pptxefhejbvbvskjvbfcbbNote 3-CEA, CBA, CUA.pptxefhejbvbvskjvbfcbb
Note 3-CEA, CBA, CUA.pptxefhejbvbvskjvbfcbb
 
Chapter 019
Chapter 019Chapter 019
Chapter 019
 
Ebm misconception myths facts
Ebm misconception myths factsEbm misconception myths facts
Ebm misconception myths facts
 
Application of EQ-5D in Reimbursement Decision Making: The Case of NICE
Application of EQ-5D in Reimbursement Decision Making: The Case of NICEApplication of EQ-5D in Reimbursement Decision Making: The Case of NICE
Application of EQ-5D in Reimbursement Decision Making: The Case of NICE
 
How to establish and evaluate clinical prediction models - Statswork
How to establish and evaluate clinical prediction models - StatsworkHow to establish and evaluate clinical prediction models - Statswork
How to establish and evaluate clinical prediction models - Statswork
 

More from Ayurdata

Statistical distributions
Statistical distributionsStatistical distributions
Statistical distributions
Ayurdata
 
BMI
BMIBMI
Health Behaviour: An Ayurveda Perspective
Health Behaviour: An Ayurveda PerspectiveHealth Behaviour: An Ayurveda Perspective
Health Behaviour: An Ayurveda Perspective
Ayurdata
 
Ayur data
Ayur data Ayur data
Ayur data
Ayurdata
 
Ayurveda colleges and courses
Ayurveda colleges and coursesAyurveda colleges and courses
Ayurveda colleges and courses
Ayurdata
 
AyurData Ayurveda Webinar
AyurData Ayurveda WebinarAyurData Ayurveda Webinar
AyurData Ayurveda Webinar
Ayurdata
 
Investigation modes in ayurveda
Investigation modes in ayurvedaInvestigation modes in ayurveda
Investigation modes in ayurveda
Ayurdata
 
Ayurveda vs allopathy
Ayurveda vs allopathyAyurveda vs allopathy
Ayurveda vs allopathy
Ayurdata
 
Meta-Analysis in Ayurveda
Meta-Analysis in AyurvedaMeta-Analysis in Ayurveda
Meta-Analysis in Ayurveda
Ayurdata
 
A manual on statistical analysis in ayurveda research
A manual on statistical analysis in ayurveda researchA manual on statistical analysis in ayurveda research
A manual on statistical analysis in ayurveda research
Ayurdata
 
Classifiers
ClassifiersClassifiers
Classifiers
Ayurdata
 
Logistic regression
Logistic regressionLogistic regression
Logistic regression
Ayurdata
 
Naive bayes
Naive bayesNaive bayes
Naive bayes
Ayurdata
 

More from Ayurdata (13)

Statistical distributions
Statistical distributionsStatistical distributions
Statistical distributions
 
BMI
BMIBMI
BMI
 
Health Behaviour: An Ayurveda Perspective
Health Behaviour: An Ayurveda PerspectiveHealth Behaviour: An Ayurveda Perspective
Health Behaviour: An Ayurveda Perspective
 
Ayur data
Ayur data Ayur data
Ayur data
 
Ayurveda colleges and courses
Ayurveda colleges and coursesAyurveda colleges and courses
Ayurveda colleges and courses
 
AyurData Ayurveda Webinar
AyurData Ayurveda WebinarAyurData Ayurveda Webinar
AyurData Ayurveda Webinar
 
Investigation modes in ayurveda
Investigation modes in ayurvedaInvestigation modes in ayurveda
Investigation modes in ayurveda
 
Ayurveda vs allopathy
Ayurveda vs allopathyAyurveda vs allopathy
Ayurveda vs allopathy
 
Meta-Analysis in Ayurveda
Meta-Analysis in AyurvedaMeta-Analysis in Ayurveda
Meta-Analysis in Ayurveda
 
A manual on statistical analysis in ayurveda research
A manual on statistical analysis in ayurveda researchA manual on statistical analysis in ayurveda research
A manual on statistical analysis in ayurveda research
 
Classifiers
ClassifiersClassifiers
Classifiers
 
Logistic regression
Logistic regressionLogistic regression
Logistic regression
 
Naive bayes
Naive bayesNaive bayes
Naive bayes
 

Recently uploaded

Analysis insight about a Flyball dog competition team's performance
Analysis insight about a Flyball dog competition team's performanceAnalysis insight about a Flyball dog competition team's performance
Analysis insight about a Flyball dog competition team's performance
roli9797
 
Learn SQL from basic queries to Advance queries
Learn SQL from basic queries to Advance queriesLearn SQL from basic queries to Advance queries
Learn SQL from basic queries to Advance queries
manishkhaire30
 
06-12-2024-BudapestDataForum-BuildingReal-timePipelineswithFLaNK AIM
06-12-2024-BudapestDataForum-BuildingReal-timePipelineswithFLaNK AIM06-12-2024-BudapestDataForum-BuildingReal-timePipelineswithFLaNK AIM
06-12-2024-BudapestDataForum-BuildingReal-timePipelineswithFLaNK AIM
Timothy Spann
 
Beyond the Basics of A/B Tests: Highly Innovative Experimentation Tactics You...
Beyond the Basics of A/B Tests: Highly Innovative Experimentation Tactics You...Beyond the Basics of A/B Tests: Highly Innovative Experimentation Tactics You...
Beyond the Basics of A/B Tests: Highly Innovative Experimentation Tactics You...
Aggregage
 
一比一原版(UO毕业证)渥太华大学毕业证如何办理
一比一原版(UO毕业证)渥太华大学毕业证如何办理一比一原版(UO毕业证)渥太华大学毕业证如何办理
一比一原版(UO毕业证)渥太华大学毕业证如何办理
aqzctr7x
 
Experts live - Improving user adoption with AI
Experts live - Improving user adoption with AIExperts live - Improving user adoption with AI
Experts live - Improving user adoption with AI
jitskeb
 
University of New South Wales degree offer diploma Transcript
University of New South Wales degree offer diploma TranscriptUniversity of New South Wales degree offer diploma Transcript
University of New South Wales degree offer diploma Transcript
soxrziqu
 
Udemy_2024_Global_Learning_Skills_Trends_Report (1).pdf
Udemy_2024_Global_Learning_Skills_Trends_Report (1).pdfUdemy_2024_Global_Learning_Skills_Trends_Report (1).pdf
Udemy_2024_Global_Learning_Skills_Trends_Report (1).pdf
Fernanda Palhano
 
原版一比一利兹贝克特大学毕业证(LeedsBeckett毕业证书)如何办理
原版一比一利兹贝克特大学毕业证(LeedsBeckett毕业证书)如何办理原版一比一利兹贝克特大学毕业证(LeedsBeckett毕业证书)如何办理
原版一比一利兹贝克特大学毕业证(LeedsBeckett毕业证书)如何办理
wyddcwye1
 
writing report business partner b1+ .pdf
writing report business partner b1+ .pdfwriting report business partner b1+ .pdf
writing report business partner b1+ .pdf
VyNguyen709676
 
原版制作(unimelb毕业证书)墨尔本大学毕业证Offer一模一样
原版制作(unimelb毕业证书)墨尔本大学毕业证Offer一模一样原版制作(unimelb毕业证书)墨尔本大学毕业证Offer一模一样
原版制作(unimelb毕业证书)墨尔本大学毕业证Offer一模一样
ihavuls
 
Challenges of Nation Building-1.pptx with more important
Challenges of Nation Building-1.pptx with more importantChallenges of Nation Building-1.pptx with more important
Challenges of Nation Building-1.pptx with more important
Sm321
 
4th Modern Marketing Reckoner by MMA Global India & Group M: 60+ experts on W...
4th Modern Marketing Reckoner by MMA Global India & Group M: 60+ experts on W...4th Modern Marketing Reckoner by MMA Global India & Group M: 60+ experts on W...
4th Modern Marketing Reckoner by MMA Global India & Group M: 60+ experts on W...
Social Samosa
 
Population Growth in Bataan: The effects of population growth around rural pl...
Population Growth in Bataan: The effects of population growth around rural pl...Population Growth in Bataan: The effects of population growth around rural pl...
Population Growth in Bataan: The effects of population growth around rural pl...
Bill641377
 
Orchestrating the Future: Navigating Today's Data Workflow Challenges with Ai...
Orchestrating the Future: Navigating Today's Data Workflow Challenges with Ai...Orchestrating the Future: Navigating Today's Data Workflow Challenges with Ai...
Orchestrating the Future: Navigating Today's Data Workflow Challenges with Ai...
Kaxil Naik
 
DATA COMMS-NETWORKS YR2 lecture 08 NAT & CLOUD.docx
DATA COMMS-NETWORKS YR2 lecture 08 NAT & CLOUD.docxDATA COMMS-NETWORKS YR2 lecture 08 NAT & CLOUD.docx
DATA COMMS-NETWORKS YR2 lecture 08 NAT & CLOUD.docx
SaffaIbrahim1
 
一比一原版兰加拉学院毕业证(Langara毕业证书)学历如何办理
一比一原版兰加拉学院毕业证(Langara毕业证书)学历如何办理一比一原版兰加拉学院毕业证(Langara毕业证书)学历如何办理
一比一原版兰加拉学院毕业证(Langara毕业证书)学历如何办理
hyfjgavov
 
Global Situational Awareness of A.I. and where its headed
Global Situational Awareness of A.I. and where its headedGlobal Situational Awareness of A.I. and where its headed
Global Situational Awareness of A.I. and where its headed
vikram sood
 
原版一比一多伦多大学毕业证(UofT毕业证书)如何办理
原版一比一多伦多大学毕业证(UofT毕业证书)如何办理原版一比一多伦多大学毕业证(UofT毕业证书)如何办理
原版一比一多伦多大学毕业证(UofT毕业证书)如何办理
mkkikqvo
 
一比一原版(UCSB文凭证书)圣芭芭拉分校毕业证如何办理
一比一原版(UCSB文凭证书)圣芭芭拉分校毕业证如何办理一比一原版(UCSB文凭证书)圣芭芭拉分校毕业证如何办理
一比一原版(UCSB文凭证书)圣芭芭拉分校毕业证如何办理
nuttdpt
 

Recently uploaded (20)

Analysis insight about a Flyball dog competition team's performance
Analysis insight about a Flyball dog competition team's performanceAnalysis insight about a Flyball dog competition team's performance
Analysis insight about a Flyball dog competition team's performance
 
Learn SQL from basic queries to Advance queries
Learn SQL from basic queries to Advance queriesLearn SQL from basic queries to Advance queries
Learn SQL from basic queries to Advance queries
 
06-12-2024-BudapestDataForum-BuildingReal-timePipelineswithFLaNK AIM
06-12-2024-BudapestDataForum-BuildingReal-timePipelineswithFLaNK AIM06-12-2024-BudapestDataForum-BuildingReal-timePipelineswithFLaNK AIM
06-12-2024-BudapestDataForum-BuildingReal-timePipelineswithFLaNK AIM
 
Beyond the Basics of A/B Tests: Highly Innovative Experimentation Tactics You...
Beyond the Basics of A/B Tests: Highly Innovative Experimentation Tactics You...Beyond the Basics of A/B Tests: Highly Innovative Experimentation Tactics You...
Beyond the Basics of A/B Tests: Highly Innovative Experimentation Tactics You...
 
一比一原版(UO毕业证)渥太华大学毕业证如何办理
一比一原版(UO毕业证)渥太华大学毕业证如何办理一比一原版(UO毕业证)渥太华大学毕业证如何办理
一比一原版(UO毕业证)渥太华大学毕业证如何办理
 
Experts live - Improving user adoption with AI
Experts live - Improving user adoption with AIExperts live - Improving user adoption with AI
Experts live - Improving user adoption with AI
 
University of New South Wales degree offer diploma Transcript
University of New South Wales degree offer diploma TranscriptUniversity of New South Wales degree offer diploma Transcript
University of New South Wales degree offer diploma Transcript
 
Udemy_2024_Global_Learning_Skills_Trends_Report (1).pdf
Udemy_2024_Global_Learning_Skills_Trends_Report (1).pdfUdemy_2024_Global_Learning_Skills_Trends_Report (1).pdf
Udemy_2024_Global_Learning_Skills_Trends_Report (1).pdf
 
原版一比一利兹贝克特大学毕业证(LeedsBeckett毕业证书)如何办理
原版一比一利兹贝克特大学毕业证(LeedsBeckett毕业证书)如何办理原版一比一利兹贝克特大学毕业证(LeedsBeckett毕业证书)如何办理
原版一比一利兹贝克特大学毕业证(LeedsBeckett毕业证书)如何办理
 
writing report business partner b1+ .pdf
writing report business partner b1+ .pdfwriting report business partner b1+ .pdf
writing report business partner b1+ .pdf
 
原版制作(unimelb毕业证书)墨尔本大学毕业证Offer一模一样
原版制作(unimelb毕业证书)墨尔本大学毕业证Offer一模一样原版制作(unimelb毕业证书)墨尔本大学毕业证Offer一模一样
原版制作(unimelb毕业证书)墨尔本大学毕业证Offer一模一样
 
Challenges of Nation Building-1.pptx with more important
Challenges of Nation Building-1.pptx with more importantChallenges of Nation Building-1.pptx with more important
Challenges of Nation Building-1.pptx with more important
 
4th Modern Marketing Reckoner by MMA Global India & Group M: 60+ experts on W...
4th Modern Marketing Reckoner by MMA Global India & Group M: 60+ experts on W...4th Modern Marketing Reckoner by MMA Global India & Group M: 60+ experts on W...
4th Modern Marketing Reckoner by MMA Global India & Group M: 60+ experts on W...
 
Population Growth in Bataan: The effects of population growth around rural pl...
Population Growth in Bataan: The effects of population growth around rural pl...Population Growth in Bataan: The effects of population growth around rural pl...
Population Growth in Bataan: The effects of population growth around rural pl...
 
Orchestrating the Future: Navigating Today's Data Workflow Challenges with Ai...
Orchestrating the Future: Navigating Today's Data Workflow Challenges with Ai...Orchestrating the Future: Navigating Today's Data Workflow Challenges with Ai...
Orchestrating the Future: Navigating Today's Data Workflow Challenges with Ai...
 
DATA COMMS-NETWORKS YR2 lecture 08 NAT & CLOUD.docx
DATA COMMS-NETWORKS YR2 lecture 08 NAT & CLOUD.docxDATA COMMS-NETWORKS YR2 lecture 08 NAT & CLOUD.docx
DATA COMMS-NETWORKS YR2 lecture 08 NAT & CLOUD.docx
 
一比一原版兰加拉学院毕业证(Langara毕业证书)学历如何办理
一比一原版兰加拉学院毕业证(Langara毕业证书)学历如何办理一比一原版兰加拉学院毕业证(Langara毕业证书)学历如何办理
一比一原版兰加拉学院毕业证(Langara毕业证书)学历如何办理
 
Global Situational Awareness of A.I. and where its headed
Global Situational Awareness of A.I. and where its headedGlobal Situational Awareness of A.I. and where its headed
Global Situational Awareness of A.I. and where its headed
 
原版一比一多伦多大学毕业证(UofT毕业证书)如何办理
原版一比一多伦多大学毕业证(UofT毕业证书)如何办理原版一比一多伦多大学毕业证(UofT毕业证书)如何办理
原版一比一多伦多大学毕业证(UofT毕业证书)如何办理
 
一比一原版(UCSB文凭证书)圣芭芭拉分校毕业证如何办理
一比一原版(UCSB文凭证书)圣芭芭拉分校毕业证如何办理一比一原版(UCSB文凭证书)圣芭芭拉分校毕业证如何办理
一比一原版(UCSB文凭证书)圣芭芭拉分校毕业证如何办理
 

Advanced statistical manual part i

  • 1. CONFIDENTIAL © 2019 AyurData Balance Calmness Serenity Introducing Advanced Statistical Manual for Ayurveda Research Kadiroo Jayaraman Praveen Venugopal AyurData
  • 2. © 2019 AyurData /CONFIDENTIAL 2 The basic manual covered the syllabus specified for M.D. students on Medical Statistics, by the Central Council of Indian Medicine. Earlier Release
  • 3. © 2019 AyurData /CONFIDENTIAL 3 In the advanced manual, we have covered more advanced statistical applications including that in data science. The mode of presentation is that the concept is introduced first, followed by illustration and the use in a real context. Some mathematics will be involved but well explained in the text. Current Release
  • 4. © 2019 AyurData /CONFIDENTIAL 4 TOPICS COVERED 1.Analysis of Repeated Measures 2.Multiple Linear Regression 3.Superiority, Bioequivalence and Non-inferiority trials 4.Logistic Regression 5.Decision Trees 6.Random Forest 7.Support Vector Machines 8.Naïve Bayes Classifier 9.Neural Networks 10.K-Nearest Neighbour Technique 11.Principal Component Analysis 12.Cluster Analysis 13.Stratified Multistage Sampling 14.Analysis of Time Series Data 15.Analysis of Time-to-event Data
  • 5. © 2019 AyurData /CONFIDENTIAL 5 ANALYSIS OF REPEATED MEASURES Repeated measurements is a common case in Ayurveda experiments. Repeated measurements on the same individual would be correlated and so require special analysis.
  • 6. © 2019 AyurData /CONFIDENTIAL 6 ANALYSIS OF REPEATED MEASURES ANOVA table for two-way with repeated measures for one factor For instance, Factor A could be treatment and B could be age group provided the patients have been stratified based on age group. In case age was a taken as a baseline variable that is continuous, it can be included as a covariate in the model. The computations and interpretations are well-explained in the manual.
  • 7. © 2019 AyurData /CONFIDENTIAL 7 MULTIPLE LINEAR REGRESSION The model we are covering is, which in the matrix form would be, The model fitting, testing and residual analysis are illustrated using a real-life dataset.
  • 8. © 2019 AyurData /CONFIDENTIAL 8 Superiority, Bioequivalence and Non-inferiority trials In many practical situations, we encounter the following types of comparisons: • The new drug is better than the standard drug. • The new drug is equivalent to the standard drug. • The new drug is at least as good as the standard drug. The hypothesis and test criterion to be employed in each of the above cases have to be different. For instance, Superiority hypothesis H0: ∆ = 0 H1: ∆ ≠ 0, or (∆ > 0, or ∆ <0 for one-tailed tests)
  • 9. © 2019 AyurData /CONFIDENTIAL 9 Superiority, Bioequivalence and Non-inferiority trials Bio-equivalence hypothesis H0: ∆ > ∆E or ∆ < -∆E H1: ∆E ≤ ∆ ≤ ∆E where ∆E is a clinically relevant equivalence margin (usually 10%). Non-inferiority hypothesis H0: ∆ ≤-∆NI H1: ∆ >-∆NI where ∆NI is a clinically relevant non-inferiority margin (usually 10%). The tests involved and the interpretation are illustrated using examples from Ayurveda.
  • 10. © 2019 AyurData /CONFIDENTIAL 10 THANK YOU © 2019 AyurData /CONFIDENTIAL 10 AyurData Team Website: http://ayurdata.in/#service-content Facebook: https://www.facebook.com/AyurData/