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Presented by
Md Sujan Hossain
DMF(State Medical Faculty)
Outline
Definition
Epidemiology
Etiology
Risk Factor
Pathogenesis
Clinical Features
Examination of Chest
Investigations
Diagnosis
Assesment of Severity
Differential Diagnosis
Complication
Management
Definition:-
 It is an acute viral infection of the bronchiole and is
characterized by cough, respiratory distress and
wheeze resulting in inflammatory obstruction.
Epidemiology:-
Occurs in children less than 2 years of age, mostly
between 2-6 months.
Highest incidence in winter, rainy season and early
spring occurs sprodically and epidemically.
Leading cause of hospitalizations in infants and young
children.
Commonest cause of lower respiratory tract infection
in infancy.
Etiology:-
Typically caused by viruses:
i. Respiratory Syncital virus
ii. Influenza virus
iii. Parainfluenza virus
iv. Human metapneumo virus
v. Rhino virus
vi. Corona virus
Occasionaly associated with mycoplasma pneumonia
infection.
Fig: Some viruses
Risk Factor:-
 Prematurity
 LBW
 Winter season
 Low socio-economic status
 Non breast feeding
 Crowded environment
 Passive smoking
 Indoor air pollution
Pathogenesis:-
 This infection of bronchioles gives rise to
Inflammatory swelling of walls of bronchioles.
Profuse mucous secretion.
Narrowing of lumen of bronchioles &
Air trapping in alveoli.
In bronchiolitis the airways becomes obstructed from
swelling of the bronchiole walls.
Clinical Features:-
 Severe respiratory distress
 Poor feeding
 Wheeze
 Cough
 Noisy respiration
 Low grade fever or no fever
 Sleeping difficulty
 Tachypnoea
 Apnoea
 Cyanosis
Fig:-A patient with acute bronchiolitis
Examination of chest:-
 Inspection:
 Fast breathing
 Suprasternal recession
 Chest indrawing
 Hyper inflated chest
 Palpation:
 No characteristic finding
 Percussion:
 Hyper resonant
 Auscultation:
 Breath sound is vesicular with prolong expiration
 Widespread rhonchi
 Sometimes fine crepitations may present
Investigations:-
X-ray of chest:
The characteristic findings are:
 Hypertranslucency: (More blackish lung fields)
 Hyperinflation: (depression of the dome of diaphragm and horizonatal
ribs)
 Increased hilar bronchial marking
CBC,CRP: Unremarkable
Fig:- A chest x-ray of bronchiolitis patient
Diagnosis:-
Based on clinical features &
relevant investigations.
Assesment of severity:-
Mild Moderate Severe
Behaviour Normal Intermittent
irritability
Increasing
irritability/Lethargy
Respiratory Rate Normal Increased Markded increase
Feeding Normal May have difficulty Unable to feed
Oxygen No requirement
SaO2 (>93%)
Mild hypoxaemia
SaO2 (90-93%)
Hypoxaemia
SaO2 (<90%)
Apnoeic episodes None May have Prolonged apnoeas
Differential Diagnosis:-
oPneumonia
oAsthma
oCongestive Heart Failure
oForeign body aspiration
oCystic Fibrosis
Complications:-
Most Common complicatios are:
 Apnoea
 Rspiratory Failure
 Secondary Infection
Management:-
Mild cases:
Counsel parent about the disease:
 Usually auto limiting disease in 5-7 days.
 Future chance of recurrent wheeze.
Home Care:
 Head up position
 Normal feeding
 Cleaning nose with normal salaine drop
 Bathing with lukewarm water
 Advice when to return hospital
Moderate Cases:-
Hospitalization:
 Oxygen inhalation: continued until
clinical improvement.
Nebulization with
Salbutamol,Budesonide
Normal feeding or NG Feeding
Supporative management
Severe cases:-
Hospitalization:
 Oxygen inhalation
Monitoring oxygen saturation by pulse oxymeter.
When severe respiratory distress & falling oxygen
saturation giving ventilator support.
NPO & give IV fluid.
Supporative management.
Although having no conclusive
benefits but other treatments are:
Steroids:
Parenteral dexamethasone may be tried only in severe
cases.
Antibiotics:
No role in bronchiolitis ( given only when secondary
bacterial infection is suspected)
Cluster clues to clinical diagnosis
Bronchiolitis:
 Age up to 2 years, peak 2-6 months
 Runny nose
 Fast breathing
 Respiratory distress
 Afebrile/ low grade fever
 Wheeze
 Normal blood count
 CXR-hypertranslucency and hyperinflation
Mind that:-
Laughing, coughing and
wheezing in a lap baby is
bronchiolitis
†Kv‡ji wkïinvwm, KvwkI ey‡KeuvwkB
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Acute bronchiolitis

  • 1. Presented by Md Sujan Hossain DMF(State Medical Faculty)
  • 2. Outline Definition Epidemiology Etiology Risk Factor Pathogenesis Clinical Features Examination of Chest Investigations Diagnosis Assesment of Severity Differential Diagnosis Complication Management
  • 3. Definition:-  It is an acute viral infection of the bronchiole and is characterized by cough, respiratory distress and wheeze resulting in inflammatory obstruction.
  • 4. Epidemiology:- Occurs in children less than 2 years of age, mostly between 2-6 months. Highest incidence in winter, rainy season and early spring occurs sprodically and epidemically. Leading cause of hospitalizations in infants and young children. Commonest cause of lower respiratory tract infection in infancy.
  • 5. Etiology:- Typically caused by viruses: i. Respiratory Syncital virus ii. Influenza virus iii. Parainfluenza virus iv. Human metapneumo virus v. Rhino virus vi. Corona virus Occasionaly associated with mycoplasma pneumonia infection. Fig: Some viruses
  • 6. Risk Factor:-  Prematurity  LBW  Winter season  Low socio-economic status  Non breast feeding  Crowded environment  Passive smoking  Indoor air pollution
  • 7. Pathogenesis:-  This infection of bronchioles gives rise to Inflammatory swelling of walls of bronchioles. Profuse mucous secretion. Narrowing of lumen of bronchioles & Air trapping in alveoli. In bronchiolitis the airways becomes obstructed from swelling of the bronchiole walls.
  • 8. Clinical Features:-  Severe respiratory distress  Poor feeding  Wheeze  Cough  Noisy respiration  Low grade fever or no fever  Sleeping difficulty  Tachypnoea  Apnoea  Cyanosis Fig:-A patient with acute bronchiolitis
  • 9. Examination of chest:-  Inspection:  Fast breathing  Suprasternal recession  Chest indrawing  Hyper inflated chest  Palpation:  No characteristic finding  Percussion:  Hyper resonant  Auscultation:  Breath sound is vesicular with prolong expiration  Widespread rhonchi  Sometimes fine crepitations may present
  • 10. Investigations:- X-ray of chest: The characteristic findings are:  Hypertranslucency: (More blackish lung fields)  Hyperinflation: (depression of the dome of diaphragm and horizonatal ribs)  Increased hilar bronchial marking CBC,CRP: Unremarkable Fig:- A chest x-ray of bronchiolitis patient
  • 11. Diagnosis:- Based on clinical features & relevant investigations.
  • 12. Assesment of severity:- Mild Moderate Severe Behaviour Normal Intermittent irritability Increasing irritability/Lethargy Respiratory Rate Normal Increased Markded increase Feeding Normal May have difficulty Unable to feed Oxygen No requirement SaO2 (>93%) Mild hypoxaemia SaO2 (90-93%) Hypoxaemia SaO2 (<90%) Apnoeic episodes None May have Prolonged apnoeas
  • 13. Differential Diagnosis:- oPneumonia oAsthma oCongestive Heart Failure oForeign body aspiration oCystic Fibrosis
  • 14. Complications:- Most Common complicatios are:  Apnoea  Rspiratory Failure  Secondary Infection
  • 15. Management:- Mild cases: Counsel parent about the disease:  Usually auto limiting disease in 5-7 days.  Future chance of recurrent wheeze. Home Care:  Head up position  Normal feeding  Cleaning nose with normal salaine drop  Bathing with lukewarm water  Advice when to return hospital
  • 16. Moderate Cases:- Hospitalization:  Oxygen inhalation: continued until clinical improvement. Nebulization with Salbutamol,Budesonide Normal feeding or NG Feeding Supporative management
  • 17. Severe cases:- Hospitalization:  Oxygen inhalation Monitoring oxygen saturation by pulse oxymeter. When severe respiratory distress & falling oxygen saturation giving ventilator support. NPO & give IV fluid. Supporative management.
  • 18. Although having no conclusive benefits but other treatments are: Steroids: Parenteral dexamethasone may be tried only in severe cases. Antibiotics: No role in bronchiolitis ( given only when secondary bacterial infection is suspected)
  • 19. Cluster clues to clinical diagnosis Bronchiolitis:  Age up to 2 years, peak 2-6 months  Runny nose  Fast breathing  Respiratory distress  Afebrile/ low grade fever  Wheeze  Normal blood count  CXR-hypertranslucency and hyperinflation
  • 20. Mind that:- Laughing, coughing and wheezing in a lap baby is bronchiolitis †Kv‡ji wkïinvwm, KvwkI ey‡KeuvwkB eªw¼IjvBwUm