The document proposes a global competitiveness strategy for the Cali Baja Bi-National Mega-Region, which combines the economies of San Diego County, Imperial County, and Baja California. It aims to attract high-tech industries like cleantech, biotech, manufacturing and logistics by leveraging the region's educated workforce, available land, low-cost manufacturing in Mexico, and potential for renewable energy development. The strategy addresses challenges like border security issues, ensuring adequate workforce training, and securing reliable sources of water and power for economic growth across the bi-national region.