This document summarizes a presentation given at the 4th International Conference on Advances in Energy Research titled "Pinch Analysis for MultiDimensional Sustainable Energy Systems Planning". It discusses how pinch analysis, a process integration technique, can be applied to model multi-objective optimization problems in sustainable energy system planning by considering factors like energy return on investment, cost, and carbon emissions. A case study applying this approach to the energy system in the Philippines is presented, showing a Pareto optimal front of solutions balancing these objectives.
This document advertises artisanal and ecological products including extra virgin olive oil produced using mills, presses, and containers. It lists a price of 3.50 euros and indicates the sale is prohibited. The document dates from December 7, 2013 through February 2014.
The document describes Microsoft Lync, an integrated communications system that provides unified communications and collaboration capabilities including instant messaging, audio and video conferencing, persistent chat, and integration with Skype and other systems. It can be deployed on-premise, as a hybrid system, or fully in Microsoft Online. Key capabilities include secure communication, scalability, virtualization support, compliance features, and federation with other systems.
Christians are being persecuted and attacked by other religious groups like Muslims in parts of the Middle East, especially in Egypt and Pakistan. Articles report on attacks from the perspective of bystanders and authorities, but often do not explain the attackers' motivations. Some attacks on Christians have no clear cause, while others stem from political issues like Christians opposing leaders or supporting military actions.
This document presents a life cycle energy analysis of various cooking fuel sources used in Indian households. It details the methodology used to determine the average daily cooking energy requirement, the energy equivalent of manual labor involved in collecting biomass fuels, and the life cycle energy efficiency of 10 cooking fuels. The results found that commercial fossil fuels like LPG and kerosene have significantly higher life cycle energy efficiencies than traditional biomass fuels. Biogas was identified as a potentially suitable and sustainable cooking fuel option for India with a life cycle energy efficiency comparable to LPG from natural gas.
Este documento presenta un libro titulado "Motivación para Emprendedores" publicado por Centro Emprende!. El libro enseña 25 hábitos para tener una vida feliz en las áreas de superación personal y relaciones sociales. El objetivo es demostrar que las personas pueden elegir y construir una vida feliz desarrollando buenos hábitos mentales y de comportamiento.
Pemerintah akan terus menyediakan SNMPTN secara gratis untuk memberi kesempatan yang sama bagi lulusan SMA/SMK untuk melanjutkan pendidikan ke PTN. SNMPTN 2014 akan diikuti oleh siswa dari 14 ribu sekolah dan akan bersaing untuk 150 ribu kursi di 63 PTN. SNMPTN memberi kesempatan khusus bagi siswa berprestasi dari keluarga kurang mampu atau daerah 3T.
Life is beautiful, though God may take things away so we can appreciate what we have been given. Sometimes losing everything teaches us the true value of what we once possessed from God. A deep breath can help in difficult times when facing loss.
This document summarizes a presentation given at the 4th International Conference on Advances in Energy Research titled "Pinch Analysis for MultiDimensional Sustainable Energy Systems Planning". It discusses how pinch analysis, a process integration technique, can be applied to model multi-objective optimization problems in sustainable energy system planning by considering factors like energy return on investment, cost, and carbon emissions. A case study applying this approach to the energy system in the Philippines is presented, showing a Pareto optimal front of solutions balancing these objectives.
This document advertises artisanal and ecological products including extra virgin olive oil produced using mills, presses, and containers. It lists a price of 3.50 euros and indicates the sale is prohibited. The document dates from December 7, 2013 through February 2014.
The document describes Microsoft Lync, an integrated communications system that provides unified communications and collaboration capabilities including instant messaging, audio and video conferencing, persistent chat, and integration with Skype and other systems. It can be deployed on-premise, as a hybrid system, or fully in Microsoft Online. Key capabilities include secure communication, scalability, virtualization support, compliance features, and federation with other systems.
Christians are being persecuted and attacked by other religious groups like Muslims in parts of the Middle East, especially in Egypt and Pakistan. Articles report on attacks from the perspective of bystanders and authorities, but often do not explain the attackers' motivations. Some attacks on Christians have no clear cause, while others stem from political issues like Christians opposing leaders or supporting military actions.
This document presents a life cycle energy analysis of various cooking fuel sources used in Indian households. It details the methodology used to determine the average daily cooking energy requirement, the energy equivalent of manual labor involved in collecting biomass fuels, and the life cycle energy efficiency of 10 cooking fuels. The results found that commercial fossil fuels like LPG and kerosene have significantly higher life cycle energy efficiencies than traditional biomass fuels. Biogas was identified as a potentially suitable and sustainable cooking fuel option for India with a life cycle energy efficiency comparable to LPG from natural gas.
Este documento presenta un libro titulado "Motivación para Emprendedores" publicado por Centro Emprende!. El libro enseña 25 hábitos para tener una vida feliz en las áreas de superación personal y relaciones sociales. El objetivo es demostrar que las personas pueden elegir y construir una vida feliz desarrollando buenos hábitos mentales y de comportamiento.
Pemerintah akan terus menyediakan SNMPTN secara gratis untuk memberi kesempatan yang sama bagi lulusan SMA/SMK untuk melanjutkan pendidikan ke PTN. SNMPTN 2014 akan diikuti oleh siswa dari 14 ribu sekolah dan akan bersaing untuk 150 ribu kursi di 63 PTN. SNMPTN memberi kesempatan khusus bagi siswa berprestasi dari keluarga kurang mampu atau daerah 3T.
Life is beautiful, though God may take things away so we can appreciate what we have been given. Sometimes losing everything teaches us the true value of what we once possessed from God. A deep breath can help in difficult times when facing loss.
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Fig.21 Indoor temperature variation in RCC and
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Fig.22 Indoor temperature variation in RCC and
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1) The document discusses the development of novel roof structures for thermal comfort and energy savings in buildings, with a focus on structures with and without phase change materials (PCMs).
2) It outlines the theoretical simulation and modeling analysis conducted
Lync2013 Deploy, Architecture and ManagmentOleg Kovalenko
The document describes Microsoft Lync, an integrated communications system that provides unified communications capabilities including audio/video conferencing, persistent chat, mobility features, and integration with Skype and other systems. It can be deployed on-premise, as a hybrid system, or fully hosted online. Key capabilities include scalability, security, compliance, efficiency and modern management features. Diagrams show example deployment architectures with on-premise, online and hybrid configurations.
The document discusses optimization of a novel photobioreactor (PBR) design using computational fluid dynamics (CFD). It proposes a new PBR design that combines features of airlift and flat plate designs. CFD simulations are used to model fluid flow and optimize design parameters. The optimized design shows improved light/dark cycling and mixing compared to conventional designs. CFD is a useful tool for virtual prototyping and optimization of novel PBR designs before physical construction.
This document discusses 10 competitors that Cisco has been unable to eliminate from the networking market. It provides brief summaries of each competitor's strategy for differentiating themselves from Cisco and sustaining their business, including a focus on specific markets (F5 Networks, Riverbed), continually leapfrogging Cisco in technology (Juniper), focusing on a niche like the data center (Arista), taking advantage of opportunities created by Cisco's actions (Polycom, Aruba), dominance in Fibre Channel switching (Brocade), grabbing share through value offerings (HP), leverage of customer familiarity (Microsoft), and continued threat in unified communications (Avaya).
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Fig.21 Indoor temperature variation in RCC and
PCM rooms January 2009
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Fig.22 Indoor temperature variation in RCC and
PCM rooms February 2009
1) The document discusses the development of novel roof structures for thermal comfort and energy savings in buildings, with a focus on structures with and without phase change materials (PCMs).
2) It outlines the theoretical simulation and modeling analysis conducted
Lync2013 Deploy, Architecture and ManagmentOleg Kovalenko
The document describes Microsoft Lync, an integrated communications system that provides unified communications capabilities including audio/video conferencing, persistent chat, mobility features, and integration with Skype and other systems. It can be deployed on-premise, as a hybrid system, or fully hosted online. Key capabilities include scalability, security, compliance, efficiency and modern management features. Diagrams show example deployment architectures with on-premise, online and hybrid configurations.
The document discusses optimization of a novel photobioreactor (PBR) design using computational fluid dynamics (CFD). It proposes a new PBR design that combines features of airlift and flat plate designs. CFD simulations are used to model fluid flow and optimize design parameters. The optimized design shows improved light/dark cycling and mixing compared to conventional designs. CFD is a useful tool for virtual prototyping and optimization of novel PBR designs before physical construction.
This document discusses 10 competitors that Cisco has been unable to eliminate from the networking market. It provides brief summaries of each competitor's strategy for differentiating themselves from Cisco and sustaining their business, including a focus on specific markets (F5 Networks, Riverbed), continually leapfrogging Cisco in technology (Juniper), focusing on a niche like the data center (Arista), taking advantage of opportunities created by Cisco's actions (Polycom, Aruba), dominance in Fibre Channel switching (Brocade), grabbing share through value offerings (HP), leverage of customer familiarity (Microsoft), and continued threat in unified communications (Avaya).
STUDIES IN SUPPORT OF SPECIAL POPULATIONS: GERIATRICS E7shruti jagirdar
Unit 4: MRA 103T Regulatory affairs
This guideline is directed principally toward new Molecular Entities that are
likely to have significant use in the elderly, either because the disease intended
to be treated is characteristically a disease of aging ( e.g., Alzheimer's disease) or
because the population to be treated is known to include substantial numbers of
geriatric patients (e.g., hypertension).
Giloy in Ayurveda - Classical Categorization and SynonymsPlanet Ayurveda
Giloy, also known as Guduchi or Amrita in classical Ayurvedic texts, is a revered herb renowned for its myriad health benefits. It is categorized as a Rasayana, meaning it has rejuvenating properties that enhance vitality and longevity. Giloy is celebrated for its ability to boost the immune system, detoxify the body, and promote overall wellness. Its anti-inflammatory, antipyretic, and antioxidant properties make it a staple in managing conditions like fever, diabetes, and stress. The versatility and efficacy of Giloy in supporting health naturally highlight its importance in Ayurveda. At Planet Ayurveda, we provide a comprehensive range of health services and 100% herbal supplements that harness the power of natural ingredients like Giloy. Our products are globally available and affordable, ensuring that everyone can benefit from the ancient wisdom of Ayurveda. If you or your loved ones are dealing with health issues, contact Planet Ayurveda at 01725214040 to book an online video consultation with our professional doctors. Let us help you achieve optimal health and wellness naturally.
Travel Clinic Cardiff: Health Advice for International TravelersNX Healthcare
Travel Clinic Cardiff offers comprehensive travel health services, including vaccinations, travel advice, and preventive care for international travelers. Our expert team ensures you are well-prepared and protected for your journey, providing personalized consultations tailored to your destination. Conveniently located in Cardiff, we help you travel with confidence and peace of mind. Visit us: www.nxhealthcare.co.uk
The biomechanics of running involves the study of the mechanical principles underlying running movements. It includes the analysis of the running gait cycle, which consists of the stance phase (foot contact to push-off) and the swing phase (foot lift-off to next contact). Key aspects include kinematics (joint angles and movements, stride length and frequency) and kinetics (forces involved in running, including ground reaction and muscle forces). Understanding these factors helps in improving running performance, optimizing technique, and preventing injuries.
Discover the benefits of homeopathic medicine for irregular periods with our guide on 5 common remedies. Learn how these natural treatments can help regulate menstrual cycles and improve overall menstrual health.
Visit Us: https://drdeepikashomeopathy.com/service/irregular-periods-treatment/
Histololgy of Female Reproductive System.pptxAyeshaZaid1
Dive into an in-depth exploration of the histological structure of female reproductive system with this comprehensive lecture. Presented by Dr. Ayesha Irfan, Assistant Professor of Anatomy, this presentation covers the Gross anatomy and functional histology of the female reproductive organs. Ideal for students, educators, and anyone interested in medical science, this lecture provides clear explanations, detailed diagrams, and valuable insights into female reproductive system. Enhance your knowledge and understanding of this essential aspect of human biology.
The skin is the largest organ and its health plays a vital role among the other sense organs. The skin concerns like acne breakout, psoriasis, or anything similar along the lines, finding a qualified and experienced dermatologist becomes paramount.
PGx Analysis in VarSeq: A User’s PerspectiveGolden Helix
Since our release of the PGx capabilities in VarSeq, we’ve had a few months to gather some insights from various use cases. Some users approach PGx workflows by means of array genotyping or what seems to be a growing trend of adding the star allele calling to the existing NGS pipeline for whole genome data. Luckily, both approaches are supported with the VarSeq software platform. The genotyping method being used will also dictate what the scope of the tertiary analysis will be. For example, are your PGx reports a standalone pipeline or would your lab’s goal be to handle a dual-purpose workflow and report on PGx + Diagnostic findings.
The purpose of this webcast is to:
Discuss and demonstrate the approaches with array and NGS genotyping methods for star allele calling to prep for downstream analysis.
Following genotyping, explore alternative tertiary workflow concepts in VarSeq to handle PGx reporting.
Moreover, we will include insights users will need to consider when validating their PGx workflow for all possible star alleles and options you have for automating your PGx analysis for large number of samples. Please join us for a session dedicated to the application of star allele genotyping and subsequent PGx workflows in our VarSeq software.
Pictorial and detailed description of patellar instability with sign and symptoms and how to diagnose , what investigations you should go with and how to approach with treatment options . I have presented this slide in my 2nd year junior residency in orthopedics at LLRM medical college Meerut and got good reviews for it
After getting it read you will definitely understand the topic.
“Psychiatry and the Humanities”: An Innovative Course at the University of Mo...Université de Montréal
“Psychiatry and the Humanities”: An Innovative Course at the University of Montreal Expanding the medical model to embrace the humanities. Link: https://www.psychiatrictimes.com/view/-psychiatry-and-the-humanities-an-innovative-course-at-the-university-of-montreal
Summer is a time for fun in the sun, but the heat and humidity can also wreak havoc on your skin. From itchy rashes to unwanted pigmentation, several skin conditions become more prevalent during these warmer months.
Nano-gold for Cancer Therapy chemistry investigatory projectSIVAVINAYAKPK
chemistry investigatory project
The development of nanogold-based cancer therapy could revolutionize oncology by providing a more targeted, less invasive treatment option. This project contributes to the growing body of research aimed at harnessing nanotechnology for medical applications, paving the way for future clinical trials and potential commercial applications.
Cancer remains one of the leading causes of death worldwide, prompting the need for innovative treatment methods. Nanotechnology offers promising new approaches, including the use of gold nanoparticles (nanogold) for targeted cancer therapy. Nanogold particles possess unique physical and chemical properties that make them suitable for drug delivery, imaging, and photothermal therapy.
NAVIGATING THE HORIZONS OF TIME LAPSE EMBRYO MONITORING.pdfRahul Sen
Time-lapse embryo monitoring is an advanced imaging technique used in IVF to continuously observe embryo development. It captures high-resolution images at regular intervals, allowing embryologists to select the most viable embryos for transfer based on detailed growth patterns. This technology enhances embryo selection, potentially increasing pregnancy success rates.
Breast cancer: Post menopausal endocrine therapyDr. Sumit KUMAR
Breast cancer in postmenopausal women with hormone receptor-positive (HR+) status is a common and complex condition that necessitates a multifaceted approach to management. HR+ breast cancer means that the cancer cells grow in response to hormones such as estrogen and progesterone. This subtype is prevalent among postmenopausal women and typically exhibits a more indolent course compared to other forms of breast cancer, which allows for a variety of treatment options.
Diagnosis and Staging
The diagnosis of HR+ breast cancer begins with clinical evaluation, imaging, and biopsy. Imaging modalities such as mammography, ultrasound, and MRI help in assessing the extent of the disease. Histopathological examination and immunohistochemical staining of the biopsy sample confirm the diagnosis and hormone receptor status by identifying the presence of estrogen receptors (ER) and progesterone receptors (PR) on the tumor cells.
Staging involves determining the size of the tumor (T), the involvement of regional lymph nodes (N), and the presence of distant metastasis (M). The American Joint Committee on Cancer (AJCC) staging system is commonly used. Accurate staging is critical as it guides treatment decisions.
Treatment Options
Endocrine Therapy
Endocrine therapy is the cornerstone of treatment for HR+ breast cancer in postmenopausal women. The primary goal is to reduce the levels of estrogen or block its effects on cancer cells. Commonly used agents include:
Selective Estrogen Receptor Modulators (SERMs): Tamoxifen is a SERM that binds to estrogen receptors, blocking estrogen from stimulating breast cancer cells. It is effective but may have side effects such as increased risk of endometrial cancer and thromboembolic events.
Aromatase Inhibitors (AIs): These drugs, including anastrozole, letrozole, and exemestane, lower estrogen levels by inhibiting the aromatase enzyme, which converts androgens to estrogen in peripheral tissues. AIs are generally preferred in postmenopausal women due to their efficacy and safety profile compared to tamoxifen.
Selective Estrogen Receptor Downregulators (SERDs): Fulvestrant is a SERD that degrades estrogen receptors and is used in cases where resistance to other endocrine therapies develops.
Combination Therapies
Combining endocrine therapy with other treatments enhances efficacy. Examples include:
Endocrine Therapy with CDK4/6 Inhibitors: Palbociclib, ribociclib, and abemaciclib are CDK4/6 inhibitors that, when combined with endocrine therapy, significantly improve progression-free survival in advanced HR+ breast cancer.
Endocrine Therapy with mTOR Inhibitors: Everolimus, an mTOR inhibitor, can be added to endocrine therapy for patients who have developed resistance to aromatase inhibitors.
Chemotherapy
Chemotherapy is generally reserved for patients with high-risk features, such as large tumor size, high-grade histology, or extensive lymph node involvement. Regimens often include anthracyclines and taxanes.