Mendel studied inheritance of traits in pea plants through selective breeding experiments. He found that traits are passed from parents to offspring through discrete units called genes. Some traits, like tallness in pea plants, are dominant and mask recessive traits. Punnett squares can predict potential combinations of traits in offspring based on parental genes. Selective breeding by humans promotes desirable inherited traits in animals and plants.
This pdf comprises of Basic of Genetics: Purpose: To convey that “Genetics is to biology what Newton’s
laws are to Physical Sciences”. Mendel’s laws, Concept of segregation and
independent assortment. Concept of allele. Gene mapping, Gene
interaction, Epistasis. Meiosis and Mitosis be taught as a part of
genetics. Emphasis to be give not to the mechanics of cell division nor the
phases but how genetic material passes from parent to offspring. Concepts
of recessiveness and dominance. Concept of mapping of phenotype to
genes. Discuss about the single gene disorders in humans. Discuss the
concept of complementation using human genetics.
This pdf comprises of Basic of Genetics: Purpose: To convey that “Genetics is to biology what Newton’s
laws are to Physical Sciences”. Mendel’s laws, Concept of segregation and
independent assortment. Concept of allele. Gene mapping, Gene
interaction, Epistasis. Meiosis and Mitosis be taught as a part of
genetics. Emphasis to be give not to the mechanics of cell division nor the
phases but how genetic material passes from parent to offspring. Concepts
of recessiveness and dominance. Concept of mapping of phenotype to
genes. Discuss about the single gene disorders in humans. Discuss the
concept of complementation using human genetics.
Human body cells contain 46 chromosomes- The first 22 pairs are called.pdfkrishnac481
Human body cells contain 46 chromosomes. The first 22 pairs are called autosomes, and they
contain numerous genes that affect the traits of the individual. The last pair, number 23, are the
sex chromosomes. The sex chromosomes determine gender (i.e., either male or female), but there
are other genes on this pair of chromosomes as well. Males sex chromosomes are XY, while
female sex chromosomes are XX . The gametes in a human (either egg cells or sperm cells)
contain only 23 chromosomes. Fertilization, the fusion of an egg and a sperm, restores the total
of 46 chromosomes in a human zygote. Non-gamete cells are called somatic cells, and they have
all 46 chromosomes in them. 1. Your sex chromosomes: XX Just as in Mendel's pea plant
experiments, genes in humans can be dominant or recessive, and the results of "crosses" can be
predicted using Punnett squares. A phenotype is the physical expression of a gene (made up of a
pair of alleles). The genotype is the actual genetic makeup of the allele pair. An individual
having two identical alleles for a gene is said to be homozygous. There can be homozygous
dominant or homozygous recessive combinations. Dominant traits are represented by capital
letters; recessive by lower case letters. An individual having non-identical alleles for a gene is
said to be heterozygous. Note that the phenotype of a heterozygous individual is determined by
the dominant gene. Dominant alleles tend to cover up the presence of any recessive alleles. In a
case of alleles that show simple dominance / recessiveness, it is not possible to know if an
individual who possesses a dominant trait has the homozygous dominant or the hatarnzunniic
nanntune haced an nhanntuns tha onlv nne wo knnwe for rertain is the Accessibility: Investigate
Example: What phenotypes and genotypes could one expect from a cross between two pea
plants, one true-breeding for yellow seeds and the other true-breeding for green seeds? Yellow
seeds are dominant to green. Complete the Punnett square below. Y The true-breeding The true-
breeding green seed plant yellow seed plant can only contribute can only contribute a recessive
allele. a dominant allele. Many human traits are controlled by a single pair of alleles and through
simple dominant and recessive rules. Example: Tongue rolling - If you can roll your tongue
lengthwise, you have the trait controlled by the dominant allele. Let " R " represent the dominant
allele in your genotype and r represent the recessive allele. If you have the dominant phenotype,
how do you know if you are homozygous dominant or heterozygous. That depends upon
knowing if one of your parents couldn't roll their tongue. For example, my Dad cannot roll his
tongue but I can. So, my genotype is Rr for this trait. If you do know know about your parents,
then you have to put both possible genotypes for yourself, i.e. RR or Rr . 2. What is your
phenotype (roller or non-roller)? 3. What is your genotype? A. If you and your parents can both
ro.
KEY CONCEPTS
14.1 Mendel used the scientific approach to identify two laws of inheritance
14.2 Probability laws govern Mendelian inheritance
14.3 Inheritance patterns are often more complex than predicted by simple Mendelian genetics
14.4 Many human traits follow Mendelian patterns of
inheritance
Professional air quality monitoring systems provide immediate, on-site data for analysis, compliance, and decision-making.
Monitor common gases, weather parameters, particulates.
Salas, V. (2024) "John of St. Thomas (Poinsot) on the Science of Sacred Theol...Studia Poinsotiana
I Introduction
II Subalternation and Theology
III Theology and Dogmatic Declarations
IV The Mixed Principles of Theology
V Virtual Revelation: The Unity of Theology
VI Theology as a Natural Science
VII Theology’s Certitude
VIII Conclusion
Notes
Bibliography
All the contents are fully attributable to the author, Doctor Victor Salas. Should you wish to get this text republished, get in touch with the author or the editorial committee of the Studia Poinsotiana. Insofar as possible, we will be happy to broker your contact.
Human body cells contain 46 chromosomes- The first 22 pairs are called.pdfkrishnac481
Human body cells contain 46 chromosomes. The first 22 pairs are called autosomes, and they
contain numerous genes that affect the traits of the individual. The last pair, number 23, are the
sex chromosomes. The sex chromosomes determine gender (i.e., either male or female), but there
are other genes on this pair of chromosomes as well. Males sex chromosomes are XY, while
female sex chromosomes are XX . The gametes in a human (either egg cells or sperm cells)
contain only 23 chromosomes. Fertilization, the fusion of an egg and a sperm, restores the total
of 46 chromosomes in a human zygote. Non-gamete cells are called somatic cells, and they have
all 46 chromosomes in them. 1. Your sex chromosomes: XX Just as in Mendel's pea plant
experiments, genes in humans can be dominant or recessive, and the results of "crosses" can be
predicted using Punnett squares. A phenotype is the physical expression of a gene (made up of a
pair of alleles). The genotype is the actual genetic makeup of the allele pair. An individual
having two identical alleles for a gene is said to be homozygous. There can be homozygous
dominant or homozygous recessive combinations. Dominant traits are represented by capital
letters; recessive by lower case letters. An individual having non-identical alleles for a gene is
said to be heterozygous. Note that the phenotype of a heterozygous individual is determined by
the dominant gene. Dominant alleles tend to cover up the presence of any recessive alleles. In a
case of alleles that show simple dominance / recessiveness, it is not possible to know if an
individual who possesses a dominant trait has the homozygous dominant or the hatarnzunniic
nanntune haced an nhanntuns tha onlv nne wo knnwe for rertain is the Accessibility: Investigate
Example: What phenotypes and genotypes could one expect from a cross between two pea
plants, one true-breeding for yellow seeds and the other true-breeding for green seeds? Yellow
seeds are dominant to green. Complete the Punnett square below. Y The true-breeding The true-
breeding green seed plant yellow seed plant can only contribute can only contribute a recessive
allele. a dominant allele. Many human traits are controlled by a single pair of alleles and through
simple dominant and recessive rules. Example: Tongue rolling - If you can roll your tongue
lengthwise, you have the trait controlled by the dominant allele. Let " R " represent the dominant
allele in your genotype and r represent the recessive allele. If you have the dominant phenotype,
how do you know if you are homozygous dominant or heterozygous. That depends upon
knowing if one of your parents couldn't roll their tongue. For example, my Dad cannot roll his
tongue but I can. So, my genotype is Rr for this trait. If you do know know about your parents,
then you have to put both possible genotypes for yourself, i.e. RR or Rr . 2. What is your
phenotype (roller or non-roller)? 3. What is your genotype? A. If you and your parents can both
ro.
KEY CONCEPTS
14.1 Mendel used the scientific approach to identify two laws of inheritance
14.2 Probability laws govern Mendelian inheritance
14.3 Inheritance patterns are often more complex than predicted by simple Mendelian genetics
14.4 Many human traits follow Mendelian patterns of
inheritance
Professional air quality monitoring systems provide immediate, on-site data for analysis, compliance, and decision-making.
Monitor common gases, weather parameters, particulates.
Salas, V. (2024) "John of St. Thomas (Poinsot) on the Science of Sacred Theol...Studia Poinsotiana
I Introduction
II Subalternation and Theology
III Theology and Dogmatic Declarations
IV The Mixed Principles of Theology
V Virtual Revelation: The Unity of Theology
VI Theology as a Natural Science
VII Theology’s Certitude
VIII Conclusion
Notes
Bibliography
All the contents are fully attributable to the author, Doctor Victor Salas. Should you wish to get this text republished, get in touch with the author or the editorial committee of the Studia Poinsotiana. Insofar as possible, we will be happy to broker your contact.
Earliest Galaxies in the JADES Origins Field: Luminosity Function and Cosmic ...Sérgio Sacani
We characterize the earliest galaxy population in the JADES Origins Field (JOF), the deepest
imaging field observed with JWST. We make use of the ancillary Hubble optical images (5 filters
spanning 0.4−0.9µm) and novel JWST images with 14 filters spanning 0.8−5µm, including 7 mediumband filters, and reaching total exposure times of up to 46 hours per filter. We combine all our data
at > 2.3µm to construct an ultradeep image, reaching as deep as ≈ 31.4 AB mag in the stack and
30.3-31.0 AB mag (5σ, r = 0.1” circular aperture) in individual filters. We measure photometric
redshifts and use robust selection criteria to identify a sample of eight galaxy candidates at redshifts
z = 11.5 − 15. These objects show compact half-light radii of R1/2 ∼ 50 − 200pc, stellar masses of
M⋆ ∼ 107−108M⊙, and star-formation rates of SFR ∼ 0.1−1 M⊙ yr−1
. Our search finds no candidates
at 15 < z < 20, placing upper limits at these redshifts. We develop a forward modeling approach to
infer the properties of the evolving luminosity function without binning in redshift or luminosity that
marginalizes over the photometric redshift uncertainty of our candidate galaxies and incorporates the
impact of non-detections. We find a z = 12 luminosity function in good agreement with prior results,
and that the luminosity function normalization and UV luminosity density decline by a factor of ∼ 2.5
from z = 12 to z = 14. We discuss the possible implications of our results in the context of theoretical
models for evolution of the dark matter halo mass function.
Slide 1: Title Slide
Extrachromosomal Inheritance
Slide 2: Introduction to Extrachromosomal Inheritance
Definition: Extrachromosomal inheritance refers to the transmission of genetic material that is not found within the nucleus.
Key Components: Involves genes located in mitochondria, chloroplasts, and plasmids.
Slide 3: Mitochondrial Inheritance
Mitochondria: Organelles responsible for energy production.
Mitochondrial DNA (mtDNA): Circular DNA molecule found in mitochondria.
Inheritance Pattern: Maternally inherited, meaning it is passed from mothers to all their offspring.
Diseases: Examples include Leber’s hereditary optic neuropathy (LHON) and mitochondrial myopathy.
Slide 4: Chloroplast Inheritance
Chloroplasts: Organelles responsible for photosynthesis in plants.
Chloroplast DNA (cpDNA): Circular DNA molecule found in chloroplasts.
Inheritance Pattern: Often maternally inherited in most plants, but can vary in some species.
Examples: Variegation in plants, where leaf color patterns are determined by chloroplast DNA.
Slide 5: Plasmid Inheritance
Plasmids: Small, circular DNA molecules found in bacteria and some eukaryotes.
Features: Can carry antibiotic resistance genes and can be transferred between cells through processes like conjugation.
Significance: Important in biotechnology for gene cloning and genetic engineering.
Slide 6: Mechanisms of Extrachromosomal Inheritance
Non-Mendelian Patterns: Do not follow Mendel’s laws of inheritance.
Cytoplasmic Segregation: During cell division, organelles like mitochondria and chloroplasts are randomly distributed to daughter cells.
Heteroplasmy: Presence of more than one type of organellar genome within a cell, leading to variation in expression.
Slide 7: Examples of Extrachromosomal Inheritance
Four O’clock Plant (Mirabilis jalapa): Shows variegated leaves due to different cpDNA in leaf cells.
Petite Mutants in Yeast: Result from mutations in mitochondrial DNA affecting respiration.
Slide 8: Importance of Extrachromosomal Inheritance
Evolution: Provides insight into the evolution of eukaryotic cells.
Medicine: Understanding mitochondrial inheritance helps in diagnosing and treating mitochondrial diseases.
Agriculture: Chloroplast inheritance can be used in plant breeding and genetic modification.
Slide 9: Recent Research and Advances
Gene Editing: Techniques like CRISPR-Cas9 are being used to edit mitochondrial and chloroplast DNA.
Therapies: Development of mitochondrial replacement therapy (MRT) for preventing mitochondrial diseases.
Slide 10: Conclusion
Summary: Extrachromosomal inheritance involves the transmission of genetic material outside the nucleus and plays a crucial role in genetics, medicine, and biotechnology.
Future Directions: Continued research and technological advancements hold promise for new treatments and applications.
Slide 11: Questions and Discussion
Invite Audience: Open the floor for any questions or further discussion on the topic.
Comparing Evolved Extractive Text Summary Scores of Bidirectional Encoder Rep...University of Maribor
Slides from:
11th International Conference on Electrical, Electronics and Computer Engineering (IcETRAN), Niš, 3-6 June 2024
Track: Artificial Intelligence
https://www.etran.rs/2024/en/home-english/
THE IMPORTANCE OF MARTIAN ATMOSPHERE SAMPLE RETURN.Sérgio Sacani
The return of a sample of near-surface atmosphere from Mars would facilitate answers to several first-order science questions surrounding the formation and evolution of the planet. One of the important aspects of terrestrial planet formation in general is the role that primary atmospheres played in influencing the chemistry and structure of the planets and their antecedents. Studies of the martian atmosphere can be used to investigate the role of a primary atmosphere in its history. Atmosphere samples would also inform our understanding of the near-surface chemistry of the planet, and ultimately the prospects for life. High-precision isotopic analyses of constituent gases are needed to address these questions, requiring that the analyses are made on returned samples rather than in situ.
The ability to recreate computational results with minimal effort and actionable metrics provides a solid foundation for scientific research and software development. When people can replicate an analysis at the touch of a button using open-source software, open data, and methods to assess and compare proposals, it significantly eases verification of results, engagement with a diverse range of contributors, and progress. However, we have yet to fully achieve this; there are still many sociotechnical frictions.
Inspired by David Donoho's vision, this talk aims to revisit the three crucial pillars of frictionless reproducibility (data sharing, code sharing, and competitive challenges) with the perspective of deep software variability.
Our observation is that multiple layers — hardware, operating systems, third-party libraries, software versions, input data, compile-time options, and parameters — are subject to variability that exacerbates frictions but is also essential for achieving robust, generalizable results and fostering innovation. I will first review the literature, providing evidence of how the complex variability interactions across these layers affect qualitative and quantitative software properties, thereby complicating the reproduction and replication of scientific studies in various fields.
I will then present some software engineering and AI techniques that can support the strategic exploration of variability spaces. These include the use of abstractions and models (e.g., feature models), sampling strategies (e.g., uniform, random), cost-effective measurements (e.g., incremental build of software configurations), and dimensionality reduction methods (e.g., transfer learning, feature selection, software debloating).
I will finally argue that deep variability is both the problem and solution of frictionless reproducibility, calling the software science community to develop new methods and tools to manage variability and foster reproducibility in software systems.
Exposé invité Journées Nationales du GDR GPL 2024
Observation of Io’s Resurfacing via Plume Deposition Using Ground-based Adapt...Sérgio Sacani
Since volcanic activity was first discovered on Io from Voyager images in 1979, changes
on Io’s surface have been monitored from both spacecraft and ground-based telescopes.
Here, we present the highest spatial resolution images of Io ever obtained from a groundbased telescope. These images, acquired by the SHARK-VIS instrument on the Large
Binocular Telescope, show evidence of a major resurfacing event on Io’s trailing hemisphere. When compared to the most recent spacecraft images, the SHARK-VIS images
show that a plume deposit from a powerful eruption at Pillan Patera has covered part
of the long-lived Pele plume deposit. Although this type of resurfacing event may be common on Io, few have been detected due to the rarity of spacecraft visits and the previously low spatial resolution available from Earth-based telescopes. The SHARK-VIS instrument ushers in a new era of high resolution imaging of Io’s surface using adaptive
optics at visible wavelengths.
Observation of Io’s Resurfacing via Plume Deposition Using Ground-based Adapt...
3.1-compressed.pptx
1. Whom do you look like?
Why do you look more like your relatives than other people?
Where do traits, such as eye color and shape, come from?
The parts of your cells that determine these traits are called genes.
Q: What are traits?
A: The characteristics that an organism has are called traits.
Look at the photo of seal on pg. 138
Q: what traits do you feel these seals received from their parents?
A: color, size ,eyes, ears.
Q: how do you think these traits are passed from parents to offspring?
A: by fertilization of male and female cells in sexual reproduction.
2. Enquiry Activity
ALB pg 69
Materials: Coin
Purpose: In this activity, students predict whether a tossed coin
will turn up heads or tails for different number of tosses.
Students will toss the coin and record the results to determine
whether their predictions were correct.
3. Pg. 140 What is heredity?
The passing of inherited traits from parents to offspring
Q: What are the different types of traits?
Traits
Inherited traits Acquired traits
traits that are passed from parent to offspring
example:
1. dogs pass their fur color to their puppies
traits that are influenced by experience or environment
example:
1. nutrition affects how large a kitten grow
2. Inherited trait in humans include height ,eye color,
dimples, freckles
2. practice may help musician gain musical skills.
5. Q: What is Genetics?
A: Genetics is the study of heredity.
Genetics is the study of how genes and how traits are passed down from one generation to the next.
Our genes carry information that affects our health, our appearance, and even our personality!
A gene is the portion of a chromosome that controls a particular inherited trait
Genes come in pairs.
You get half of your genes from your mother
and the other half from your father.
6. Some scientists were curious about basic questions of life: Where did it come from? Why is it so varied?
Why do children look like their parents?
To answer these questions, they study a type of biology called GENetics (juh-net-icks).
"Gen" means beginning.
The science of genetics began in the 1800s when Gregor Mendel, an Austrian monk,
figured out how traits are inherited by studying peas.
7. Pg. 142 What did Mendel do?
v Mendel cultivated thousands of pea plants in his garden.
v He kept precise records of the pea plants.
v He experimented with pea plants to study how traits are passed from parent plants to their
offspring.
v Through this work Mendel revealed for himself some basic properties of heredity.
v Today, many consider Mendel to be the founder of genetics.
9. Q: Why did Mendel chose pea plants for his study?
A: To study genetics, Mendel chose to work with pea plants because
1. they have identifiable traits.
example - pea plant is either tall or short which is an easy trait to observe.
2. pea plants grow quickly
so Mendel could complete many experiments in a short period of time.
3. pea plants can either self-pollinate or cross-pollinate.
Self-pollination- the transfer of pollen from the anther of a flower to the stigma of the same flower.
Cross-pollination- the transfer of pollen from the anther of a flower to the stigma of the another flower
10. In one of his early experiments, Mendel crossed a tall pea plant and a tall pea plant.
What do you think the offspring of these plants were?
11. Next, Mendel crossed a tall pea plant and a short pea plant.
What do you think the offspring of these plants were?
Mendel observed that every one of the hybrid was tall.
Hybrid: Organisms that have inherited two different forms of the same trait, one from each paren
12. Why were the hybrids tall? What happened to the short trait?
Mendel believed that the trait of short plant was present but was hidden by the trait of tall plant.
He hypothesized that the presence of tall trait prevented the short trait from appearing.
Mendel named the tall traits as dominant trait while the short hidden trait as the recessive trait.
According to the law of dominance, one trait in a gene pair will be dominant over the other.
For example,
1. When pea plants with smooth seeds were crossed with plants with wrinkled seeds
all seeds in first generation were found to be round.
Q: Identify the dominant and recessive trait in seeds of pea plant
A: Dominant – smooth Recessive - wrinkled
2. When pea plants with purple flowers were crossed with plants with white flowers.
all flowers in first generation were found to be purple.
Q: Identify the dominant and recessive trait in flowers of pea plant
A: Dominant – purple Recessive - white
13. Q: Differentiate between Dominant trait and recessive trait.
Dominant Recessive
The trait that masks the other form of the trait is called
Dominant trait
The hidden form of the trait is the recessive trait..
The dominant trait is represented in capital letters.
Example : tall pea plant (T)
The recessive trait is represented in small letters.
Example: short pea plant (t)
Some of the dominant features observed in humans are:- Some of the recessive features observed in humans are:-
Right handedness
Almond- shaped eyes
Detached earlobes
Left- handedness,
Round eyes
Attached earlobes
15. Pg. 144 Why is Mendel’s work important?
Mendel’s work can be used to predict the traits of offspring from crossing two organism.
To further understand heredity,Mendel used the concept of mathematical relationship called ratios.
In 1905, English geneticist Reginald Punnett created a technique to illustrate some of
Mendel’s discoveries. His technique employs what we now call a Punnett square.
Q: What is a Punnett Square?
A: This is a simple graphical way of discovering all of the potential combinations of traits that can occur in
children, given the traits of their parents.
Punnett square predicts the possible outcomes of genetic crosses
16. Q: How is a Punnett square made?
A: To make a Punnett square:
1. First, divide a large square evenly into 4 smaller squares.
2. Next, the female’s genes are written outside down the left and the male’s genes are written outside along to top
3. The results of a cross between them is found by carrying the letters downward and across into the boxes.
17. TT = pure tall
Tt = hybrid tall
tt= pure short
18. Draw a Punnett square to determine the possible outcomes of a cross for an offspring with one parent
having brown eyes and the other blue.
Use the capital letter 'B' to represent brown color of the eye and the lowercase letter ‘b' to represent blue.
(to be done in class)
What is the probability that the offspring will have blue eyes?
a.
b.
25%
50%
c. 75%
d. 100%
19. Activity: Pompom/Beads Punnett Squares
1.Fill lunch-size paper bags with 12 yellow and 12 green pompoms. Divide students into groups
of four. Provide each student with a Punnett Square activity sheet, a Punnett square chart and a
bag of yellow and green pompoms.
1.In each group, students will take turns being Parent 1 and Parent 2. Each parent will close
their eyes and choose two pompoms from the bag. They will then begin creating a Punnett
square on their chart by placing their pompoms in the space provided for Parent 1 and for
Parent 2. The group will use the remaining pompoms to fill out the rest of the Punnett square.
3. Each student will record the results on their Punnett Square activity sheet using a Y to
represent yellow seeds and a g to represent green seeds. Underneath each Punnett square,
students can record the probability of the offspring having yellow or green seeds.
Example:
When a hybrid pea plant with yellow seeds is crossed
with another hybrid pea plant with yellow seeds,
there is a 75% probability that the offspring will have
yellow seeds and a 25% probability that the offspring
will have green seeds. It is important to note that in
the case of a hybrid, the dominant trait is what will be
expressed.
21. Pg. 146 What is selective breeding?
Mating certain organisms in order to promote offspring with desirable trait is called selective breeding.
Q: What is a breed?
A: Members of an animal species with similar traits are part of a group called a breed.
Selective breeding is when humans choose which animals or plants breed together.
For example: Dairy farmers use selective breeding to produce cows that give large volumes of milk
and chickens that produce large eggs.
22. Discussion Questions
•Why would people use selective breeding?
•What might go wrong if a breed of animal or variety of plant is constantly used to breed others?
Q: What are the advantages and disadvantages of selective breeding?
A:
Advantages Disadvantages
Produces animals with specific desirable traits Decreased variation.
that humans want.
Can bring out harmful recessive traits or
Example: Small schnauzers were bred to hunt diseases can accumulate in the population
rats.
Example: deaf dalmatians, boxers with heart
disease, Labradors with hip problem.
Example: Milk cows produce more milk