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Artificial hybrids & biofuels
In the last decade, the application of new molecular techniques has helped to identify Saccharomyces species and suggested many types of reticulated evolutionary events, such as hybridization, interspecies recombination, introgression, horizontal gene transfer, and admixture. Many strains isolated from fermentative environments, such as S. bayanus, which was isolated from beer or fermented beverages, and S. pastorianus, used in making lager beer, have been misidentified as distinct species when they have chromosome contributions from two or more natural Saccharomyces species. These hybridization events likely occurred in the stressful conditions found in industrial environments where hybrids were better suited. These hybrids do not have unique origins, suggesting that hybridization has a clear selective advantage. We have recently described two well-differentiated Patagonian populations of S. eubayanus, the wild contributor to S. pastorianus (S. cerevisiae x S. eubayanus) lager-brewing strains. The application of the state-of-the-art phylogenetic methods (Supernetworks and Bayesian concordance factor analysis) illuminated many reticulation events in S. eubayanus outside of Patagonia and uncovered the relationship between one population of S. eubayanus from Patagonia and its counterpart in S. bayanus and S. pastorianus. We also recently isolated S. eubayanus strains from Sheboygan, WI that originated by intraspecific hybridization (admixture) of the two Patagonian populations, and we used supernetworks to graphically represent the hybridization and recombination in S. bayanus and S. pastorianus from the brewing industry. With the knowledge gained by understanding the process of hybrid evolution that occurred in winemaking and brewing environments, we are developing new methods to generate artificial hybrids to repeat the hybridization process for the bioethanol industry.
1. Product Packaging Into
We want to improve our product packaging to better communicate with customers, attract the right talent, and meet customer needs. An internal approach would involve assessing current customers and their needs to analyze requirements. An external approach defines the key skills required from students and how to effectively communicate with them. Our method would create a value proposition for the talent management product, segment job descriptions, and define needs and priorities for sub-products.
Randomization
This document discusses randomized computation and algorithms. It begins with an introduction to randomized algorithms like randomized quicksort and polynomial identity testing. It then covers computational models for probabilistic Turing machines and complexity classes like BPP, RP and ZPP that are defined using randomization. The document also characterizes these classes using quantifiers and discusses error reduction techniques for BPP.
Prva tehnicka skola_2015_2016_upis
Прва техничка школа у Крагујевцу пружа широку лепезу занимања за упис у први разред средње школе.
3. Need Assessment Report SGH E&Y
The need assessment report identifies key competencies needed by employers versus those possessed by current students. It finds a significant gap, with students only meeting 4 of 10 important competencies. These competencies include language skills, open-mindedness, engagement, responsibility, ethics, prioritization, ability to work in teams, time management, flexibility, and effective communication. The report questions how to connect employer needs with educating students on the current job market.
Mining Saccharomyces diversity and experimental evolution for cellulosic biof...
The document summarizes research on using experimental evolution and hybridization of Saccharomyces yeasts to develop strains for improved cellulosic biofuel production. Key points include:
- The diversity of Saccharomyces yeasts was mapped and certain lineages were selected for hybridization based on traits like tolerance.
- Hybrids were generated between S. cerevisiae (the chassis strain) and other species and then experimentally evolved over 50 generations.
- The evolved hybrid strains showed improved utilization of xylose compared to ancestor strains, producing similar ethanol levels without accumulating byproducts.
- Genome analysis found the evolved hybrids were mostly triploid and had chromosomal rearrangements replacing parent genes.
- Further work aims to
Recommended
Artificial hybrids & biofuels
In the last decade, the application of new molecular techniques has helped to identify Saccharomyces species and suggested many types of reticulated evolutionary events, such as hybridization, interspecies recombination, introgression, horizontal gene transfer, and admixture. Many strains isolated from fermentative environments, such as S. bayanus, which was isolated from beer or fermented beverages, and S. pastorianus, used in making lager beer, have been misidentified as distinct species when they have chromosome contributions from two or more natural Saccharomyces species. These hybridization events likely occurred in the stressful conditions found in industrial environments where hybrids were better suited. These hybrids do not have unique origins, suggesting that hybridization has a clear selective advantage. We have recently described two well-differentiated Patagonian populations of S. eubayanus, the wild contributor to S. pastorianus (S. cerevisiae x S. eubayanus) lager-brewing strains. The application of the state-of-the-art phylogenetic methods (Supernetworks and Bayesian concordance factor analysis) illuminated many reticulation events in S. eubayanus outside of Patagonia and uncovered the relationship between one population of S. eubayanus from Patagonia and its counterpart in S. bayanus and S. pastorianus. We also recently isolated S. eubayanus strains from Sheboygan, WI that originated by intraspecific hybridization (admixture) of the two Patagonian populations, and we used supernetworks to graphically represent the hybridization and recombination in S. bayanus and S. pastorianus from the brewing industry. With the knowledge gained by understanding the process of hybrid evolution that occurred in winemaking and brewing environments, we are developing new methods to generate artificial hybrids to repeat the hybridization process for the bioethanol industry.
1. Product Packaging Into
We want to improve our product packaging to better communicate with customers, attract the right talent, and meet customer needs. An internal approach would involve assessing current customers and their needs to analyze requirements. An external approach defines the key skills required from students and how to effectively communicate with them. Our method would create a value proposition for the talent management product, segment job descriptions, and define needs and priorities for sub-products.
Randomization
This document discusses randomized computation and algorithms. It begins with an introduction to randomized algorithms like randomized quicksort and polynomial identity testing. It then covers computational models for probabilistic Turing machines and complexity classes like BPP, RP and ZPP that are defined using randomization. The document also characterizes these classes using quantifiers and discusses error reduction techniques for BPP.
Prva tehnicka skola_2015_2016_upis
Прва техничка школа у Крагујевцу пружа широку лепезу занимања за упис у први разред средње школе.
3. Need Assessment Report SGH E&Y
The need assessment report identifies key competencies needed by employers versus those possessed by current students. It finds a significant gap, with students only meeting 4 of 10 important competencies. These competencies include language skills, open-mindedness, engagement, responsibility, ethics, prioritization, ability to work in teams, time management, flexibility, and effective communication. The report questions how to connect employer needs with educating students on the current job market.
Mining Saccharomyces diversity and experimental evolution for cellulosic biof...
The document summarizes research on using experimental evolution and hybridization of Saccharomyces yeasts to develop strains for improved cellulosic biofuel production. Key points include:
- The diversity of Saccharomyces yeasts was mapped and certain lineages were selected for hybridization based on traits like tolerance.
- Hybrids were generated between S. cerevisiae (the chassis strain) and other species and then experimentally evolved over 50 generations.
- The evolved hybrid strains showed improved utilization of xylose compared to ancestor strains, producing similar ethanol levels without accumulating byproducts.
- Genome analysis found the evolved hybrids were mostly triploid and had chromosomal rearrangements replacing parent genes.
- Further work aims to
3. Need Assessment - To Upgrade
This document outlines a need assessment to upgrade processes for recruiting members. It examines both external factors like key skills employers need and youth values, as well as an internal review of competencies required, bottlenecks, and desired improvements. The internal approach analyzes requirements and assesses needs by comparing the current and desired states of recruitment processes. Areas identified for improvement include making the competency model and application process easier to understand, reducing mistakes, increasing diversity, and adjusting materials and flexibility to different locations.
S.eubayanus & reticulate evolution
Saccharomyces has become a model genus for evolution and genomics. Improvements in genome sequencing and isolation protocols will allow us to produce high-quality genome sequences for all the major populations and lineages. In the mean time, multilocus phylogenetic and population genetic approaches are helping classify our strain collection for population genomic studies. In this talk, I will introduce some of the advances we have made in the description of populations of the newly discovered species S. eubayanus, the wild stock of lager-brewing hybrids. Using a combined pipeline of population and phylogenetic studies, we have described two well-differentiated populations in Patagonia (Argentina), indicating that S. eubayanus is native. Although S. eubayanus may not be endemic to South America, it is likely native. Lager-brewing hybrids isolated in Europe showed shared alleles with the S. eubayanus population P-B (L) and had low genetic diversity, suggesting the S. eubayanus alleles involved in hybridization were drawn from a small subpopulation derived from P-B (L). From our Wild YEAST Program, a yeast isolation project conducted by undergraduate students and citizen scientists from across the world, we identified three new S. eubayanus strains from Sheboygan, WI (USA). In contrast to the clear population differentiation in Patagonia, the North American strains represent a recent and possibly transient admixture of the two Patagonian populations. To capture reticulation and summarize it in a phylogenetic framework, we combine state-of-the-art Bayesian methods with phylogenetic network analysis. Our findings support the hypothesis that genetically divergent microbes can produce rare but economically important hybrids when they migrate from their natural ecological context.
Wisconsin Science Festival - Spanish Scientists in USA
Science description of some members of ECUSA@Midwest. ECUSA members participated on 21st and 22nd in the Wisconsin Science Festival in Madison.
Ciencia desarrollada por miembros de ECUSA@Midwest. Los miembros de ECUSA participaron durante el 21 y el 22 de octubre en el Festival de Ciencia de Wisconsin, Madison.
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3. Need Assessment - To Upgrade
This document outlines a need assessment to upgrade processes for recruiting members. It examines both external factors like key skills employers need and youth values, as well as an internal review of competencies required, bottlenecks, and desired improvements. The internal approach analyzes requirements and assesses needs by comparing the current and desired states of recruitment processes. Areas identified for improvement include making the competency model and application process easier to understand, reducing mistakes, increasing diversity, and adjusting materials and flexibility to different locations.
S.eubayanus & reticulate evolution
Saccharomyces has become a model genus for evolution and genomics. Improvements in genome sequencing and isolation protocols will allow us to produce high-quality genome sequences for all the major populations and lineages. In the mean time, multilocus phylogenetic and population genetic approaches are helping classify our strain collection for population genomic studies. In this talk, I will introduce some of the advances we have made in the description of populations of the newly discovered species S. eubayanus, the wild stock of lager-brewing hybrids. Using a combined pipeline of population and phylogenetic studies, we have described two well-differentiated populations in Patagonia (Argentina), indicating that S. eubayanus is native. Although S. eubayanus may not be endemic to South America, it is likely native. Lager-brewing hybrids isolated in Europe showed shared alleles with the S. eubayanus population P-B (L) and had low genetic diversity, suggesting the S. eubayanus alleles involved in hybridization were drawn from a small subpopulation derived from P-B (L). From our Wild YEAST Program, a yeast isolation project conducted by undergraduate students and citizen scientists from across the world, we identified three new S. eubayanus strains from Sheboygan, WI (USA). In contrast to the clear population differentiation in Patagonia, the North American strains represent a recent and possibly transient admixture of the two Patagonian populations. To capture reticulation and summarize it in a phylogenetic framework, we combine state-of-the-art Bayesian methods with phylogenetic network analysis. Our findings support the hypothesis that genetically divergent microbes can produce rare but economically important hybrids when they migrate from their natural ecological context.
Wisconsin Science Festival - Spanish Scientists in USA
Science description of some members of ECUSA@Midwest. ECUSA members participated on 21st and 22nd in the Wisconsin Science Festival in Madison.
Ciencia desarrollada por miembros de ECUSA@Midwest. Los miembros de ECUSA participaron durante el 21 y el 22 de octubre en el Festival de Ciencia de Wisconsin, Madison.
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Wisconsin Science Festival - Spanish Scientists in USA
Wisconsin Science Festival - Spanish Scientists in USA
3. Need Assessment PARP
- 2. External approach ❑Key competencies and skills required from students ❑Students interest and values ❑Employment issues
- 3. Key Questions Key 21st century competencies? Employers needs in times of youth unemployment? Youth Values?
- 4. Key Questions of my report Key 21st century competencies? Employers needs in times of youth unemployment?
- 5. Key 21st century competencies? Odporność na stres Umiejętność przystosowania się do zmieniających warunków(zmiana miejsca zamieszkania, pracy, znajomych czy otoczenia) Pogodzenie życia prywatnego z zawodowym Chęć do rozwoju Umiejętność krytycznego myślenia i rozwiązywania problemów Praca zespołowa Podejmowanie inicjatywy Samodzielność i odpowiedzialność Efektywna komunikacja Ciekawość świata
- 6. What are the employers needs in times of youth unemployment?