A LOV2 Domain-Based Optogenetic Tool to Control Protein Degradation and Cellu...Feynman Liang
The document describes the development of a photosensitive degron (psd) module that allows for light-activated and reversible protein degradation. The psd module is based on a light-oxygen-voltage (LOV) domain from plants and a degradation domain. Testing showed that the psd module enables specific, cryptic, quantitative, and reversible degradation of target proteins in yeast cells. The technique was applied to control the yeast cell cycle and conditionally degrade various yeast genes. Compartmentalized modeling supported the experimental findings.
Este documento describe la importancia de la tecnología y el internet en la educación y la sociedad. Actualmente estamos experimentando grandes cambios sociales y culturales debido al desarrollo de las tecnologías de la información y la comunicación. El internet es una herramienta perfecta para eliminar distancias y permitir la libre expresión, pero también conlleva riesgos si no se usa de forma adecuada y responsable.
Project management involves planning and controlling temporary endeavors to achieve unique goals within constraints. A project has defined start and end dates, resources, and deliverables. It requires leadership and coordination across interdependent tasks. Common project management techniques include work breakdown structures, Gantt charts, critical path methods, and network diagrams to schedule activities and monitor progress. The critical path is the longest sequence of dependent tasks that determines the project's duration.
The document provides instructions for constructing a network diagram for a construction project to build a new gymnasium. It includes an activity list with 37 tasks required to complete the project, along with the duration and predecessor tasks for each. To construct the network diagram, one must identify each task as a node and use arrows to show the precedence relationships between tasks based on which must be completed before others can begin. This will provide the schedule for the construction of the new gymnasium.
The document discusses a proposed Seoul Jar Project. The project would involve selling jars that people can fill with items representing different parts of Seoul, such as dirt, leaves, or water. The filled jars would then be exhibited with the creators' names to introduce others to Seoul. A group would organize the project, exhibit the jars, and provide suggestions for filling them. Funding methods and timelines are considered, with the goal of helping people feel proud to represent their city through creative works.
The document discusses project scheduling and network diagrams. It defines key terms like activity duration, early start/finish times, late start/finish times, float, free float, and critical path. It explains that activity durations are determined based on crew size and output. Network calculations are used to determine the early and late start/finish times to establish the critical path and project duration. The critical path is the longest path through the network with the least amount of float.
Detecting paraphrases using recursive autoencodersFeynman Liang
Presentation on deep learning applied to natural language processing, presented at University of Cambridge Machine Learning Group's Research and Communication Club 2-11-2015 meeting.
A LOV2 Domain-Based Optogenetic Tool to Control Protein Degradation and Cellu...Feynman Liang
The document describes the development of a photosensitive degron (psd) module that allows for light-activated and reversible protein degradation. The psd module is based on a light-oxygen-voltage (LOV) domain from plants and a degradation domain. Testing showed that the psd module enables specific, cryptic, quantitative, and reversible degradation of target proteins in yeast cells. The technique was applied to control the yeast cell cycle and conditionally degrade various yeast genes. Compartmentalized modeling supported the experimental findings.
Este documento describe la importancia de la tecnología y el internet en la educación y la sociedad. Actualmente estamos experimentando grandes cambios sociales y culturales debido al desarrollo de las tecnologías de la información y la comunicación. El internet es una herramienta perfecta para eliminar distancias y permitir la libre expresión, pero también conlleva riesgos si no se usa de forma adecuada y responsable.
Project management involves planning and controlling temporary endeavors to achieve unique goals within constraints. A project has defined start and end dates, resources, and deliverables. It requires leadership and coordination across interdependent tasks. Common project management techniques include work breakdown structures, Gantt charts, critical path methods, and network diagrams to schedule activities and monitor progress. The critical path is the longest sequence of dependent tasks that determines the project's duration.
The document provides instructions for constructing a network diagram for a construction project to build a new gymnasium. It includes an activity list with 37 tasks required to complete the project, along with the duration and predecessor tasks for each. To construct the network diagram, one must identify each task as a node and use arrows to show the precedence relationships between tasks based on which must be completed before others can begin. This will provide the schedule for the construction of the new gymnasium.
The document discusses a proposed Seoul Jar Project. The project would involve selling jars that people can fill with items representing different parts of Seoul, such as dirt, leaves, or water. The filled jars would then be exhibited with the creators' names to introduce others to Seoul. A group would organize the project, exhibit the jars, and provide suggestions for filling them. Funding methods and timelines are considered, with the goal of helping people feel proud to represent their city through creative works.
The document discusses project scheduling and network diagrams. It defines key terms like activity duration, early start/finish times, late start/finish times, float, free float, and critical path. It explains that activity durations are determined based on crew size and output. Network calculations are used to determine the early and late start/finish times to establish the critical path and project duration. The critical path is the longest path through the network with the least amount of float.
Detecting paraphrases using recursive autoencodersFeynman Liang
Presentation on deep learning applied to natural language processing, presented at University of Cambridge Machine Learning Group's Research and Communication Club 2-11-2015 meeting.
This document discusses project management. It defines a project as a collection of linked activities with a start and end point to achieve a specific result. Project management is described as a dynamic process that utilizes resources in a controlled manner to achieve clearly defined objectives. The key aspects of project management are planning, organizing, controlling, and measuring. It explains that project management is important as it helps map out a course of action, think systematically, and monitor progress against the plan. Consequences of not using project management include delay, cost overruns, waste of resources, lower quality, and dissatisfaction.
El documento describe los recursos tecnológicos como las computadoras e Internet y su importancia en la educación y la sociedad. Explica que Internet es una poderosa herramienta para buscar, crear y transferir información de manera libre, pero también conlleva riesgos si no se usa de forma responsable y cuidadosa, especialmente para los niños.
This document discusses key aspects of software project management from Ian Sommerville's Software Engineering textbook. It covers objectives of project management, including planning, scheduling, and risk management. It also describes distinctive characteristics of software projects, such as intangible products and flexible requirements. Project management aims to deliver software on time and on budget by establishing plans, estimating timelines, and identifying/mitigating risks.
The document discusses project scheduling and network diagrams. It defines key terms like work breakdown structure and activities. It explains that a network schedule graphically shows the logical sequence of project events. A network diagram is developed by defining activities and determining which must precede or follow others. The diagram shows the efficient order that work will follow to complete the project. Milestones mark important points but do not consume time or resources like activities.
Scheduling is important during the pre-construction, construction, and post-construction phases of a project. A bar chart or Gantt chart is a simple scheduling method that shows project activities as horizontal bars along a timeline, indicating start and end dates. A network-based schedule is a more complex method that depicts all project activities and their logical relationships in a network diagram. It assigns duration and sequence to each activity. Network scheduling is the most powerful tool for accurately planning and managing construction projects.
This presentation summarizes a mid-term project on designing jars to introduce Seoul. It discusses research conducted on similar projects, jar materials, and a project prototype. It presented the project workflow, from buying a jar, filling it with items from Seoul and labeling it, to group exhibition. It also addressed problems identified in pre-research like location limits, and solutions like adding delivery and targeting student groups. A project website was launched for promotion.
This document discusses project management. It defines a project as a collection of linked activities with a start and end point to achieve a specific result. Project management is described as a dynamic process that utilizes resources in a controlled manner to achieve clearly defined objectives. The key aspects of project management are planning, organizing, controlling, and measuring. It explains that project management is important as it helps map out a course of action, think systematically, and monitor progress against the plan. Consequences of not using project management include delay, cost overruns, waste of resources, lower quality, and dissatisfaction.
El documento describe los recursos tecnológicos como las computadoras e Internet y su importancia en la educación y la sociedad. Explica que Internet es una poderosa herramienta para buscar, crear y transferir información de manera libre, pero también conlleva riesgos si no se usa de forma responsable y cuidadosa, especialmente para los niños.
This document discusses key aspects of software project management from Ian Sommerville's Software Engineering textbook. It covers objectives of project management, including planning, scheduling, and risk management. It also describes distinctive characteristics of software projects, such as intangible products and flexible requirements. Project management aims to deliver software on time and on budget by establishing plans, estimating timelines, and identifying/mitigating risks.
The document discusses project scheduling and network diagrams. It defines key terms like work breakdown structure and activities. It explains that a network schedule graphically shows the logical sequence of project events. A network diagram is developed by defining activities and determining which must precede or follow others. The diagram shows the efficient order that work will follow to complete the project. Milestones mark important points but do not consume time or resources like activities.
Scheduling is important during the pre-construction, construction, and post-construction phases of a project. A bar chart or Gantt chart is a simple scheduling method that shows project activities as horizontal bars along a timeline, indicating start and end dates. A network-based schedule is a more complex method that depicts all project activities and their logical relationships in a network diagram. It assigns duration and sequence to each activity. Network scheduling is the most powerful tool for accurately planning and managing construction projects.
This presentation summarizes a mid-term project on designing jars to introduce Seoul. It discusses research conducted on similar projects, jar materials, and a project prototype. It presented the project workflow, from buying a jar, filling it with items from Seoul and labeling it, to group exhibition. It also addressed problems identified in pre-research like location limits, and solutions like adding delivery and targeting student groups. A project website was launched for promotion.