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CASE REPORT December 2022
Journal of Ayurveda and Integrated Medical Sciences | December 2022 | Vol. 7 | Issue 11 255
Effective management of newly diagnosed case of
Prameha with Vasanthika Vamana - A single case study
Bhagyashree1
, Shaila Borannavar2
1
Post Graduate Scholar, Dept. of PG Studies in Panchakarma, Govt. Ayurveda Medical College, Bengaluru, Karnataka, India.
2
Associate Professor, Dept. of PG Studies in Panchakarma, Govt. Ayurveda Medical College, Bengaluru, Karnataka, India.
INTRODUCTION
Diabetes mellitus is a syndrome of disordered
metabolism and inappropriate hyperglycaemia
secondary to an absolute relative deficiency of insulin
or reduction in biological effectiveness of insulin or
both.[1]
It is considered as the fastest growing disorder
of present era in public sector, affecting about 9.3% of
world population (2019) and may rise up to 10.2% by
the end of 2030.[2]
By the year 2035, nearly 592 million
people are predicted to die of diabetes.[3]
Listed under
Address for correspondence:
Dr. Bhagyashree
Post Graduate Scholar, Dept. of PG Studies in Panchakarma,
Govt. Ayurveda Medical College, Bengaluru, Karnataka, India.
E-mail: shreebhagyabhat13@gmail.com
Submission Date: 09/10/2022 Accepted Date: 16/11/2022
Access this article online
Quick Response Code
Website: www.jaims.in
Published by Maharshi Charaka
Ayurveda Organization, Vijayapur,
Karnataka (Regd) under the license
CC-by-NC-SA
metabolic disorder, DM caused mainly by improper
lifestyle and with very high rate of morbidity and
mortality.
Based on pathology the disease is classified into two
types:
1. Type 1 DM (insulin deficiency) - Autoimmune
condition due to reduced or complete absence of
insulin production.
2. Type 2 DM - a heterogeneous group of disorder
characterised by variable degree of insulin
resistance, impaired insulin secretion and
excessive hepatic glucose production.
The signs and symptoms of the disease are polyuria,
polydipsia, weight loss, fatigue, increased frequency of
micturition, frequent infection, poor wound healing
etc. In early type 2 DM, symptoms may be more subtle
and consist of fatigue, poor wound healing, and
paresthesias. The lack of symptoms is the main reason
for the delayed diagnosis of type 2 DM.
Without the proper treatment, the disease will easily
move into grievous compilatory stages like
A B S T R A C T
Diabetes mellitus is the group of metabolic conditions with constant hyperglycaemia results from defects
in insulin production or uptake. Type 2 Diabetes is the most common reason for hyperglycaemia mainly
affecting people around age of 40 with lack of exercises and sedentary lifestyle. The increase in incidence
of disease and its easy growing complications have become threat to healthcare sector even after the
discovery of various hypoglycaemic agents and synthetic insulin. These medicines with long term use
are reported to have hazardous side effects. In Ayurveda similar condition has been mentioned under
the disease spectrum of Prameha. The line of management of Prameha is to aim at the control of
hyperglycaemia along with removing the root cause of the disease. Samshodhana is the line of treatment
mentioned for the treatment of Prameha and proper Rutu Shodhana will help to get rid of many
Santharpanotha Vyadhis as they do timely elimination of vitiated Dosha. The purpose of this study to
evaluate the efficacy of Vasanthika Vamana in Diabetes mellitus in preventing and curative way. In
present study, Vasanthika Vamana Karma proved as best treatment in controlling subjective symptoms
and blood sugar levels.
Key words: Case Report, Diabetes mellitus, Vasanthika Vamana Karma, Emesis, Shodhana
Bhagyashree et al. Effective management of newly diagnosed case of Prameha
ISSN: 2456-3110 CASE REPORT December 2022
Journal of Ayurveda and Integrated Medical Sciences | December 2022 | Vol. 7 | Issue 11 256
▪ Ocular: Diabetic retinopathy, macular oedema,
glaucoma.
▪ Renal: Proteinuria, end-stage renal disease (ESRD),
type IV renal tubular acidosis
▪ Neurologic: Distal symmetric polyneuropathy,
polyradiculopathy, mononeuropathy, autonomic
neuropathy
▪ Gastrointestinal: Gastroparesis, diarrhoea,
constipation
▪ Genitourinary: Cystopathy, erectile dysfunction,
female sexual dysfunction, vaginal candidiasis
▪ Cardiovascular: Coronary artery disease,
congestive heart failure, peripheral vascular
disease, stroke
▪ Lower extremity: Foot deformity (hammer toe,
claw toe, Charcot foot), ulceration, amputation
▪ Dermatologic: Infections (folliculitis, furunculosis,
cellulitis), necrobiosis, poor healing, ulcers,
gangrene.[4]
Even with highly developed medical field, with the
existing treatment strategies it has been difficult to
stop the progress of the disease and to prevent the
development of complications. Thus, effective
prevention and management of disease has become
the need of an hour.
The disease is considered under the broad spectrum of
the Prameha Vyadhi in Ayurveda which is given as
common name for collective group of 20 disease
condition with similar Prathyatma Lakshana. It is
characterised by increased excessive turbid urine.[5]
The vitiation Kapha along with Kleda, Abaddha Meda
and other Dhatu leads to Prameha. As the disease
progress, involvement of Tridosha and Dasha Dushyas
i.e., Rasa, Rakta, Mamsa, Meda, Majja, Shukra,
Shareera Kleda, Vasa, Laseeka and Ojus are also
seen.[6]
When aggravated Kapha vitiates Meda,
Mamsa, increased Kleda in body, brings them to
Moothrashaya and forms 10 types of Kaphaja
Prameha.[7]
Similarly other types of Prameha with
vitiation of Pitta and Vata Dosha causes 6 types Pittaja
Prameha and 4 types of Vataja Prameha respectively.
For Chikitsa purpose this Pramehi can be further
classified into Sthula Pramehi and Krisha Pramehi.[8]
Samshodhana is the line of treatment in Sthula
Pramehi where as in Krisha Pramehi Santharpana is the
main line of treatment. Further Sushrutha Acharya
mentions when the disease is fully developed with
signs and symptoms one should do Shodhana
Chikitsa.[9]
Under Shodhana both Vamana and
Virechana is indicated for which Dalhana Acharya
specifies, in Kaphaja Meha Vamana is the indicated
treatment whereas in Pittaja Meha Virechana.[10]
For
the understanding the pathology, Madhumeha a type
of Vataja Meha can be considered as 2 types-
Apatarpaniya or Dhatukshayaja Samprapti and
Santarpaniya or Avarana Janya Samprapti. With the
factors causing vitiation of Vata dosha causes vitiation
of other Dhatus and leads to Dhatukshayaja Prameha.
Tha nidanas causing vitiation of Kapha and Pitta leads
to Dusti of Dhatus and leads to Avarana Janya
Prameha.[11]
Samshodhana specilly Vamana is helpful
in the Sthula Pramehi with Avarana Janya
Samprapti.Thus, for prevention and control of the
disease Samshodhana especially Rutu Shodhana,
Pathya Ahara and proper Vyayama plays important
role.
CASE REPORT
A female patient of 47 years age is K/c/o
Hypothyroidism for 5 years, under regular Ayurvedic
medication for the same. She was complaining of
generalised body ache, increased thirst and appetite,
dryness of mouth for 4 months along with increased
frequency nocturnal micturition and excessive
sweating. There were no complaints of burning
sensation or numbness over bilateral feet, weight loss
etc. Along with these symptoms she was also having
pain in low back region radiating to right thigh. For all
these complaints she consulted Panchakarma Opd (6A)
of SJIIM Bengaluru. After analysing all the complaints,
we asked her to undergo haematological investigation,
where results showed there was increase in Fasting
blood sugar and Post Prandial blood sugar, and HbA1C
was 6.4. After assessing all the symptoms, we
conducted Vasanthika Vamana.
Bhagyashree et al. Effective management of newly diagnosed case of Prameha
ISSN: 2456-3110 CASE REPORT December 2022
Journal of Ayurveda and Integrated Medical Sciences | December 2022 | Vol. 7 | Issue 11 257
Past history: K/c/o Hypothyroidism since years and is
taking Ayurvedic medications.
Family history: Mother was k/c/o Hypothyroidism.
Menstrual history: 2-3 days /30-35 days – regular
cycle, No dysmenorrhea, white discharge.
Personal history
Diet: Both veg and non veg food. She has the habit of
taking curd daily, food article with dominance of sweet
taste and Occasionally bakery food item.
Appetite: Increased. (Abhyavarana Shakti - Pravara,
Jarana Shakti - Madhyama)
Mala: Baddha, once in 2 days
Mutra: Increased frequency (9-10 times /day, 2-3
times / night), Colour - whitish yellow (burning
micturition occasionally, no foul smell) Nidra - Sound
sleep. Habit of taking day sleep of 30min.
Examinations
Table 1: Showing Examination finding in the patient
General Examination
Appearance - Healthy
Consciousness - Alert
Height - 5.3 feet (158.5 cm)
Weight - 80 kg
BMI - 32
BP - 110/70 mm hg
Pulse - 64/min
Temperature - 98.6°F
Pallor - absent
Icterus - absent
Cyanosis - absent
Clubbing - absent
Lymphadenopathy - absent
Central Nervous System Examination
▪ Higher mental functions - normal
▪ Oriented to time place and person
▪ No abnormality detected.
Gastro Intestinal System Examination
Shape of abdomen - slightly protuberant
Palpation
No Abnormality detected
Cardio Vascular System Examination
S1 S2 heard, no abnormality detected
Respiratory System Examination
NVBS heard, no abnormality detected
Musculoskeletal system examination
Doorbel sign - + ve at L3-L4 level
SLR – negative
Gait- Normal
ROM of spine - Restricted.
Astasthana Pareeksha
Table 2: Showing Astasthana Pareeksha
Pareeksha Findings
Nadi Manda Gati, 64b/min
Moothra Prabhoota, 9-10 times / day; 2-3 times / night
Mala Baddha (once in 2 days)
Jihva Ishat Lipta
Shabda Prakrita
Sparsha Prakritha
Drik Prakrita
Akriti Sthula
Bhagyashree et al. Effective management of newly diagnosed case of Prameha
ISSN: 2456-3110 CASE REPORT December 2022
Journal of Ayurveda and Integrated Medical Sciences | December 2022 | Vol. 7 | Issue 11 258
Dashavidha Pareeksha
Table 3: Showing Dashavidha Pareeksha
Prakruthi Kapha Vata
Vikrathi Kaphapradhana Tridosha
Sara Twak, Mamsa, Medo Sara
Samhanana Uttama
Satva Madhyama
Sathmya Madhyama
Ahara Abhyavaharana Shakthi - Pravara
Jarana Shakthi - Madhyama
Vyayama Shakti Avara
Pramana Supramanitha
Vaya Madhyama
Investigations
Table 4: Showing investigations
Investigation (20/4/2022) Findings
FBS 169
PPBS 232
HbA1C 6.4%
Treatment Protocol
Table 5: Showing treatment protocol
Deepana
Pachana
For 3 days with Bhoonimbadi Choorna :
5gm-5gm-5gm B/f with Warm water
Shodananga
Snehapana
Varunadi Gritha
D1-30 ml
D2-70 ml
D3-130 ml
D4-180 ml
D5-200 ml
Vishramakala 1 day - Abhyanga with Dhanvantaram
Taila f/b Ushnajala Snana
2 day - Kaphotkleshakara Ahara (Idli, curd
rice, Dhoodpeda, Ksheera Payasa )
Vamana Karma With Madnaphala Yoga - 15 gm
(Madanaphala Pippali Choorna: 5gm
Yesti Madhu Choorna: 3 gm
Vacha: 1 gm
Honey: 5 gm
Saindhava: 1gm)
Samsarjana
Krama
For 5 days
Shamanoushadhi Nishakatakadi Kashyaya 15ml -0-15 ml b/f
Shilajithwadi Vati 1-1-1 A/F
Simhanada Guggulu 2-2-2 A/F for 2
months
Assessment
Objective Criteria
Table 6: Showing objective assessment of criteria
Before
Treatm
ent
After Treatment
Date 20/4/20
22
08/05/20
22
8/6/20
22
18/6/20
22
09/09/20
22
FBS 169 96 70 87 72
PPBS 232 110 101 119 112
HbA
1c
6.4% - - - 5.5 %
Subjective Criteria
Table 7: Showing subjective assessment of criteria
Before Treatment After Treatment
Fatigue +++ +
Bhagyashree et al. Effective management of newly diagnosed case of Prameha
ISSN: 2456-3110 CASE REPORT December 2022
Journal of Ayurveda and Integrated Medical Sciences | December 2022 | Vol. 7 | Issue 11 259
Excessive
nocturnal
micturition
+++ 0
Increased hunger +++ +
Excessive sweating +++ 0
+++ : severe form of symptoms, ++ : moderate form of symptoms, + :
mild form of symptoms, 0 : absence of symptoms.
DISCUSSION
Diabetes mellitus (DM) comprises a group of metabolic
disorder that share the common feature of
inappropriately elevated blood glucose levels. Among
two types, type 2 DM is most common and mainly
affecting people around the age group 40. Diabetes
mellitus has already become a leading threat to public
health globally with its increased incidence. In India
over the past 3 decades, the burden of DM in terms of
deaths and disabilities has reached more than double.
In Ayurveda the disease is mentioned under the
category of Prameha. Prameha is one among
Astamahagada considered as Agrya among Anushangi
Vyadhi. It is mentioned in Brihatrayis with well
elaborated etiologies, prodromal symptoms,
Lakshanas and complications. While considering
Chikitsa of any Vyadhi we come across
Nidanaparivarjana Chikitsa, Samprapti Vighatana
Chikitsa and Lakshanika Chikitsa etc. classifications. In
the disease like Prameha, achieving the Nidana
Parivarjana and Samprapti Vighatana are utmost
important.
When we look into Samprapti, Kapha Pradhana
Tridosha along with Shareera Kleda, Meda and Mamsa
are predominantly vitiated leading to symptoms of
Prabhoota Avila Moothrata. To breakdown the
Samprapti, Shodhana especially Vamana Karma is
useful. Samshodhana Karma plays important role in
eliminating the vitiated doshas out of the body from its
root there by leaving less chance for its
reoccurrence.[12]
Vasanthika Vamana helps in
removing the Prakupitha Kapha Dosha which is
accumulated and aggravated due to Rutu Prabhava of
previous Sheetha Rutus, also easy elimination of Dosha
with proper Shuddhi and without complications
compared to other Rutu.[13]
In the present study, the patient of Kapha Pitta Prakriti,
we conducted classical Vasanthika Vamana. As part of
Poorvakarma, Deepana Pachana was given with
Bhoonimbadi Choorna. It is helpful in increasing
Jataragni, causes Amapachana and thereby prepares
the body for Snehapana.
Arohana Krama Shodananga Snehapana in Madhyama
Matra is given using Varunadi Gritha which is having
drugs mainly acts as Kapha Medohara. This helps the
Doshas undergo Vridhi, Vishyandhana there by helps in
bringing Doshas from Kosta To Shaka.
After proper Samyak Snigdha Lakshanas, patient was
given two days of Vishramakala during which
Abhyanga with Ksheerabala Taila and Ushna Jala
Snana was advised. Second day of Vishrama Kala
patient was given with Kaphotkleshakara Ahara.
Bahyasnehana and Swedana helps in liquefaction and
disintegration of Dosha and brings them to Kosta.
Kaphotkleshakara Ahara aids in smooth conduction of
Vamana Karma.
Vamana Karma was conducted in early morning 6 to 8
AM, Akanta Pana was given with Ksheera as it was
palatable to patient and Madanaphala Yoga is given as
Vamaka Dravya along with Yastimadhu Phanta as
Vamanopaga Dravya till Pittanta Darshana. There
were 7 Vega and 3 Upavega with Uttama Shudhi and
followed the Samsarjana Krama of 5 days by following
the food articles mentioned in the Ayurvedic classics.
After Samsarjana it was found out that there was
marked reduction in signs and symptoms in patients
especially increased frequency of urination, fatigue,
excessive hunger and after completion of Samsarjana
Krama, previously increased FBS and PPBS came to
normal range and maintained within normal limit for
consecutive 3 months with Shamanoushadhi.
CONCLUSION
Rutu Shodhana helps to remove the embedded Doshas
out of the body timely, Vasanthika Vamana does the
abolishment of Kaphadosha thus helps in breakdown
the Samprapti of the disease Prameha. It was observed
Bhagyashree et al. Effective management of newly diagnosed case of Prameha
ISSN: 2456-3110 CASE REPORT December 2022
Journal of Ayurveda and Integrated Medical Sciences | December 2022 | Vol. 7 | Issue 11 260
the Vasanthika Vamana showed significant effect in
controlling blood glucose level and managing signs and
symptoms of Prameha like Prahoota Moothrata, Ati
Kshud, Galatalu Shosha, Atisweda etc. With proper
Samshodhana along with Vyayama and dietary habits
one can prevent and control the disease Prameha
without the use of any antiglycemic agents.
REFERENCES
1. DL Kasper et al. 19th edition, Harrisons Manual of medicine,
Endocrinology- Diabetes mellitus, MC Graw Hill Education,
2016, P904.
2. https://www.diabetesresearchclinicalpractice.com/article/SO
168-8227(19)31230-6/fulltext.
3. Tao Z, Shi A, Zhao J. Epidemiological perspectives of diabetes,
Cell Biochem Biophys 20015;73:181-5.
4. DL Kasper et al., 19th edition, Harrisons Manual of Medicine,
Endocrinology - Diabetes mellitus, MC Graw Hill Education,
2016, P905-6.
5. Acharya YT (ed.), Susruta Samhita of Susruta with the
Nibandhasangraha Commentary of Sri Dalhanacharya and the
Nyayachandrika Panjika of Sri Gayadasacharya on
Nidanastana, Nidana sthana 32nd chapter, 6th verse Varanasi:
Chaukhamba Surbharati Prakashan, 2014, Pn.290.
6. Acharya YT (ed.), Charaka Samhita of Agnivesha elaborated by
Charaka and Drdhabala with Ayurveda Dipika commentary by
Sri Chakrapanidatta, Nidana sthana 4th chapter 7th verse,
Varanasi: Chaukhamba Surbharati Prakashan, 2014, pn.212.
7. Acharya YT (ed.), Charaka Samhita of Agnivesha elaborated by
Charaka and Drdhabala with Ayurveda Dipika commentary by
Sri Chakrapanidatta, Nidana sthana 4th chapter 9 verse,
Varanasi: Chaukhamba Surbharati Prakashan, 2014, pn.213.
8. Acharya YT (ed.), Charaka Samhita of Agnivesha elaborated by
Charaka and Drdhabala with Ayurveda Dipika commentary by
Sri Chakrapanidatta, Chikitsa sthana 6th chapter 15th verse,
Varanasi: Chaukhamba Surbharati Prakashan, 2014, p446.
9. Acharya YT (ed.), Susruta Samhita of Susruta with the
Nibandhasangraha Commentary of Sri Dalhanacharya and the
Nyayachandrika Panjika of Sri Gayadasacharya on
Nidanastana, Chikitsasthana 12th chapter 4th verse, Varanasi:
Chaukhamba Surbharati Prakashan, 2014, P454.
10. Acharya YT (ed.), Susruta Samhita of Susruta with the
Nibandhasangraha Commentary of Sri Dalhanacharya and the
Nyayachandrika Panjika of Sri Gayadasacharya on
Nidanastana,chikitsa sthana 11th chapter, Varanasi:
Chaukhamba Surbharati Prakashan, 2014, P452.
11. Paradakara HSS (ed.), Astanga Hrdaya of Vagbhata with the
commentaries Sarvangasudara of Arunadatta and
Ayurvedarasayana of Hemadri, Nidanastana 10th chapter 18-
19th verse, Chaukhamba Sanskrit Samsthan, Varanasi, 2016,
P504.
12. Acharya YT (ed.), Charaka Samhita of Agnivesha elaborated by
Charaka and Drdhabala with Ayurveda deepika commentary
by Sri Chakrapanidatta, Sutrasthana 16th chapter 21st verse,
Varanasi: Choukamba Surbharati Prakashan, 2014,P97.
13. Paradakara HSS (ed.), Astanga Hrdaya of Vagbhata with the
commentaries Sarvangasudara of Arunadatta and Ayurveda
Rasayana of Hemadri, Sutrasthana 4th Chapter, 35th verse,
Chaukhamba Sanskrit Samsthan, Varanasi, 2016, P59.
*******************************
How to cite this article: Bhagyashree, Shaila
Borannavar. Effective management of newly diagnosed
case of Prameha with Vasanthika Vamana - A single case
study. J Ayurveda Integr Med Sci 2022;11:255-260.
Source of Support: Nil, Conflict of Interest: None
declared.
Copyright © 2022 The Author(s); Published by Maharshi Charaka Ayurveda Organization, Vijayapur (Regd). This is an open-access article distributed under the terms
of the Creative Commons Attribution License (https://creativecommons.org/licenses/by-nc-sa/4.0), which permits unrestricted use, distribution, and perform the
work and make derivative works based on it only for non-commercial purposes, provided the original work is properly cited.

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Diabetes mellitus
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2106-Article Text-4978-1-10-20230119.pdf

  • 1.
  • 2. CASE REPORT December 2022 Journal of Ayurveda and Integrated Medical Sciences | December 2022 | Vol. 7 | Issue 11 255 Effective management of newly diagnosed case of Prameha with Vasanthika Vamana - A single case study Bhagyashree1 , Shaila Borannavar2 1 Post Graduate Scholar, Dept. of PG Studies in Panchakarma, Govt. Ayurveda Medical College, Bengaluru, Karnataka, India. 2 Associate Professor, Dept. of PG Studies in Panchakarma, Govt. Ayurveda Medical College, Bengaluru, Karnataka, India. INTRODUCTION Diabetes mellitus is a syndrome of disordered metabolism and inappropriate hyperglycaemia secondary to an absolute relative deficiency of insulin or reduction in biological effectiveness of insulin or both.[1] It is considered as the fastest growing disorder of present era in public sector, affecting about 9.3% of world population (2019) and may rise up to 10.2% by the end of 2030.[2] By the year 2035, nearly 592 million people are predicted to die of diabetes.[3] Listed under Address for correspondence: Dr. Bhagyashree Post Graduate Scholar, Dept. of PG Studies in Panchakarma, Govt. Ayurveda Medical College, Bengaluru, Karnataka, India. E-mail: shreebhagyabhat13@gmail.com Submission Date: 09/10/2022 Accepted Date: 16/11/2022 Access this article online Quick Response Code Website: www.jaims.in Published by Maharshi Charaka Ayurveda Organization, Vijayapur, Karnataka (Regd) under the license CC-by-NC-SA metabolic disorder, DM caused mainly by improper lifestyle and with very high rate of morbidity and mortality. Based on pathology the disease is classified into two types: 1. Type 1 DM (insulin deficiency) - Autoimmune condition due to reduced or complete absence of insulin production. 2. Type 2 DM - a heterogeneous group of disorder characterised by variable degree of insulin resistance, impaired insulin secretion and excessive hepatic glucose production. The signs and symptoms of the disease are polyuria, polydipsia, weight loss, fatigue, increased frequency of micturition, frequent infection, poor wound healing etc. In early type 2 DM, symptoms may be more subtle and consist of fatigue, poor wound healing, and paresthesias. The lack of symptoms is the main reason for the delayed diagnosis of type 2 DM. Without the proper treatment, the disease will easily move into grievous compilatory stages like A B S T R A C T Diabetes mellitus is the group of metabolic conditions with constant hyperglycaemia results from defects in insulin production or uptake. Type 2 Diabetes is the most common reason for hyperglycaemia mainly affecting people around age of 40 with lack of exercises and sedentary lifestyle. The increase in incidence of disease and its easy growing complications have become threat to healthcare sector even after the discovery of various hypoglycaemic agents and synthetic insulin. These medicines with long term use are reported to have hazardous side effects. In Ayurveda similar condition has been mentioned under the disease spectrum of Prameha. The line of management of Prameha is to aim at the control of hyperglycaemia along with removing the root cause of the disease. Samshodhana is the line of treatment mentioned for the treatment of Prameha and proper Rutu Shodhana will help to get rid of many Santharpanotha Vyadhis as they do timely elimination of vitiated Dosha. The purpose of this study to evaluate the efficacy of Vasanthika Vamana in Diabetes mellitus in preventing and curative way. In present study, Vasanthika Vamana Karma proved as best treatment in controlling subjective symptoms and blood sugar levels. Key words: Case Report, Diabetes mellitus, Vasanthika Vamana Karma, Emesis, Shodhana
  • 3. Bhagyashree et al. Effective management of newly diagnosed case of Prameha ISSN: 2456-3110 CASE REPORT December 2022 Journal of Ayurveda and Integrated Medical Sciences | December 2022 | Vol. 7 | Issue 11 256 ▪ Ocular: Diabetic retinopathy, macular oedema, glaucoma. ▪ Renal: Proteinuria, end-stage renal disease (ESRD), type IV renal tubular acidosis ▪ Neurologic: Distal symmetric polyneuropathy, polyradiculopathy, mononeuropathy, autonomic neuropathy ▪ Gastrointestinal: Gastroparesis, diarrhoea, constipation ▪ Genitourinary: Cystopathy, erectile dysfunction, female sexual dysfunction, vaginal candidiasis ▪ Cardiovascular: Coronary artery disease, congestive heart failure, peripheral vascular disease, stroke ▪ Lower extremity: Foot deformity (hammer toe, claw toe, Charcot foot), ulceration, amputation ▪ Dermatologic: Infections (folliculitis, furunculosis, cellulitis), necrobiosis, poor healing, ulcers, gangrene.[4] Even with highly developed medical field, with the existing treatment strategies it has been difficult to stop the progress of the disease and to prevent the development of complications. Thus, effective prevention and management of disease has become the need of an hour. The disease is considered under the broad spectrum of the Prameha Vyadhi in Ayurveda which is given as common name for collective group of 20 disease condition with similar Prathyatma Lakshana. It is characterised by increased excessive turbid urine.[5] The vitiation Kapha along with Kleda, Abaddha Meda and other Dhatu leads to Prameha. As the disease progress, involvement of Tridosha and Dasha Dushyas i.e., Rasa, Rakta, Mamsa, Meda, Majja, Shukra, Shareera Kleda, Vasa, Laseeka and Ojus are also seen.[6] When aggravated Kapha vitiates Meda, Mamsa, increased Kleda in body, brings them to Moothrashaya and forms 10 types of Kaphaja Prameha.[7] Similarly other types of Prameha with vitiation of Pitta and Vata Dosha causes 6 types Pittaja Prameha and 4 types of Vataja Prameha respectively. For Chikitsa purpose this Pramehi can be further classified into Sthula Pramehi and Krisha Pramehi.[8] Samshodhana is the line of treatment in Sthula Pramehi where as in Krisha Pramehi Santharpana is the main line of treatment. Further Sushrutha Acharya mentions when the disease is fully developed with signs and symptoms one should do Shodhana Chikitsa.[9] Under Shodhana both Vamana and Virechana is indicated for which Dalhana Acharya specifies, in Kaphaja Meha Vamana is the indicated treatment whereas in Pittaja Meha Virechana.[10] For the understanding the pathology, Madhumeha a type of Vataja Meha can be considered as 2 types- Apatarpaniya or Dhatukshayaja Samprapti and Santarpaniya or Avarana Janya Samprapti. With the factors causing vitiation of Vata dosha causes vitiation of other Dhatus and leads to Dhatukshayaja Prameha. Tha nidanas causing vitiation of Kapha and Pitta leads to Dusti of Dhatus and leads to Avarana Janya Prameha.[11] Samshodhana specilly Vamana is helpful in the Sthula Pramehi with Avarana Janya Samprapti.Thus, for prevention and control of the disease Samshodhana especially Rutu Shodhana, Pathya Ahara and proper Vyayama plays important role. CASE REPORT A female patient of 47 years age is K/c/o Hypothyroidism for 5 years, under regular Ayurvedic medication for the same. She was complaining of generalised body ache, increased thirst and appetite, dryness of mouth for 4 months along with increased frequency nocturnal micturition and excessive sweating. There were no complaints of burning sensation or numbness over bilateral feet, weight loss etc. Along with these symptoms she was also having pain in low back region radiating to right thigh. For all these complaints she consulted Panchakarma Opd (6A) of SJIIM Bengaluru. After analysing all the complaints, we asked her to undergo haematological investigation, where results showed there was increase in Fasting blood sugar and Post Prandial blood sugar, and HbA1C was 6.4. After assessing all the symptoms, we conducted Vasanthika Vamana.
  • 4. Bhagyashree et al. Effective management of newly diagnosed case of Prameha ISSN: 2456-3110 CASE REPORT December 2022 Journal of Ayurveda and Integrated Medical Sciences | December 2022 | Vol. 7 | Issue 11 257 Past history: K/c/o Hypothyroidism since years and is taking Ayurvedic medications. Family history: Mother was k/c/o Hypothyroidism. Menstrual history: 2-3 days /30-35 days – regular cycle, No dysmenorrhea, white discharge. Personal history Diet: Both veg and non veg food. She has the habit of taking curd daily, food article with dominance of sweet taste and Occasionally bakery food item. Appetite: Increased. (Abhyavarana Shakti - Pravara, Jarana Shakti - Madhyama) Mala: Baddha, once in 2 days Mutra: Increased frequency (9-10 times /day, 2-3 times / night), Colour - whitish yellow (burning micturition occasionally, no foul smell) Nidra - Sound sleep. Habit of taking day sleep of 30min. Examinations Table 1: Showing Examination finding in the patient General Examination Appearance - Healthy Consciousness - Alert Height - 5.3 feet (158.5 cm) Weight - 80 kg BMI - 32 BP - 110/70 mm hg Pulse - 64/min Temperature - 98.6°F Pallor - absent Icterus - absent Cyanosis - absent Clubbing - absent Lymphadenopathy - absent Central Nervous System Examination ▪ Higher mental functions - normal ▪ Oriented to time place and person ▪ No abnormality detected. Gastro Intestinal System Examination Shape of abdomen - slightly protuberant Palpation No Abnormality detected Cardio Vascular System Examination S1 S2 heard, no abnormality detected Respiratory System Examination NVBS heard, no abnormality detected Musculoskeletal system examination Doorbel sign - + ve at L3-L4 level SLR – negative Gait- Normal ROM of spine - Restricted. Astasthana Pareeksha Table 2: Showing Astasthana Pareeksha Pareeksha Findings Nadi Manda Gati, 64b/min Moothra Prabhoota, 9-10 times / day; 2-3 times / night Mala Baddha (once in 2 days) Jihva Ishat Lipta Shabda Prakrita Sparsha Prakritha Drik Prakrita Akriti Sthula
  • 5. Bhagyashree et al. Effective management of newly diagnosed case of Prameha ISSN: 2456-3110 CASE REPORT December 2022 Journal of Ayurveda and Integrated Medical Sciences | December 2022 | Vol. 7 | Issue 11 258 Dashavidha Pareeksha Table 3: Showing Dashavidha Pareeksha Prakruthi Kapha Vata Vikrathi Kaphapradhana Tridosha Sara Twak, Mamsa, Medo Sara Samhanana Uttama Satva Madhyama Sathmya Madhyama Ahara Abhyavaharana Shakthi - Pravara Jarana Shakthi - Madhyama Vyayama Shakti Avara Pramana Supramanitha Vaya Madhyama Investigations Table 4: Showing investigations Investigation (20/4/2022) Findings FBS 169 PPBS 232 HbA1C 6.4% Treatment Protocol Table 5: Showing treatment protocol Deepana Pachana For 3 days with Bhoonimbadi Choorna : 5gm-5gm-5gm B/f with Warm water Shodananga Snehapana Varunadi Gritha D1-30 ml D2-70 ml D3-130 ml D4-180 ml D5-200 ml Vishramakala 1 day - Abhyanga with Dhanvantaram Taila f/b Ushnajala Snana 2 day - Kaphotkleshakara Ahara (Idli, curd rice, Dhoodpeda, Ksheera Payasa ) Vamana Karma With Madnaphala Yoga - 15 gm (Madanaphala Pippali Choorna: 5gm Yesti Madhu Choorna: 3 gm Vacha: 1 gm Honey: 5 gm Saindhava: 1gm) Samsarjana Krama For 5 days Shamanoushadhi Nishakatakadi Kashyaya 15ml -0-15 ml b/f Shilajithwadi Vati 1-1-1 A/F Simhanada Guggulu 2-2-2 A/F for 2 months Assessment Objective Criteria Table 6: Showing objective assessment of criteria Before Treatm ent After Treatment Date 20/4/20 22 08/05/20 22 8/6/20 22 18/6/20 22 09/09/20 22 FBS 169 96 70 87 72 PPBS 232 110 101 119 112 HbA 1c 6.4% - - - 5.5 % Subjective Criteria Table 7: Showing subjective assessment of criteria Before Treatment After Treatment Fatigue +++ +
  • 6. Bhagyashree et al. Effective management of newly diagnosed case of Prameha ISSN: 2456-3110 CASE REPORT December 2022 Journal of Ayurveda and Integrated Medical Sciences | December 2022 | Vol. 7 | Issue 11 259 Excessive nocturnal micturition +++ 0 Increased hunger +++ + Excessive sweating +++ 0 +++ : severe form of symptoms, ++ : moderate form of symptoms, + : mild form of symptoms, 0 : absence of symptoms. DISCUSSION Diabetes mellitus (DM) comprises a group of metabolic disorder that share the common feature of inappropriately elevated blood glucose levels. Among two types, type 2 DM is most common and mainly affecting people around the age group 40. Diabetes mellitus has already become a leading threat to public health globally with its increased incidence. In India over the past 3 decades, the burden of DM in terms of deaths and disabilities has reached more than double. In Ayurveda the disease is mentioned under the category of Prameha. Prameha is one among Astamahagada considered as Agrya among Anushangi Vyadhi. It is mentioned in Brihatrayis with well elaborated etiologies, prodromal symptoms, Lakshanas and complications. While considering Chikitsa of any Vyadhi we come across Nidanaparivarjana Chikitsa, Samprapti Vighatana Chikitsa and Lakshanika Chikitsa etc. classifications. In the disease like Prameha, achieving the Nidana Parivarjana and Samprapti Vighatana are utmost important. When we look into Samprapti, Kapha Pradhana Tridosha along with Shareera Kleda, Meda and Mamsa are predominantly vitiated leading to symptoms of Prabhoota Avila Moothrata. To breakdown the Samprapti, Shodhana especially Vamana Karma is useful. Samshodhana Karma plays important role in eliminating the vitiated doshas out of the body from its root there by leaving less chance for its reoccurrence.[12] Vasanthika Vamana helps in removing the Prakupitha Kapha Dosha which is accumulated and aggravated due to Rutu Prabhava of previous Sheetha Rutus, also easy elimination of Dosha with proper Shuddhi and without complications compared to other Rutu.[13] In the present study, the patient of Kapha Pitta Prakriti, we conducted classical Vasanthika Vamana. As part of Poorvakarma, Deepana Pachana was given with Bhoonimbadi Choorna. It is helpful in increasing Jataragni, causes Amapachana and thereby prepares the body for Snehapana. Arohana Krama Shodananga Snehapana in Madhyama Matra is given using Varunadi Gritha which is having drugs mainly acts as Kapha Medohara. This helps the Doshas undergo Vridhi, Vishyandhana there by helps in bringing Doshas from Kosta To Shaka. After proper Samyak Snigdha Lakshanas, patient was given two days of Vishramakala during which Abhyanga with Ksheerabala Taila and Ushna Jala Snana was advised. Second day of Vishrama Kala patient was given with Kaphotkleshakara Ahara. Bahyasnehana and Swedana helps in liquefaction and disintegration of Dosha and brings them to Kosta. Kaphotkleshakara Ahara aids in smooth conduction of Vamana Karma. Vamana Karma was conducted in early morning 6 to 8 AM, Akanta Pana was given with Ksheera as it was palatable to patient and Madanaphala Yoga is given as Vamaka Dravya along with Yastimadhu Phanta as Vamanopaga Dravya till Pittanta Darshana. There were 7 Vega and 3 Upavega with Uttama Shudhi and followed the Samsarjana Krama of 5 days by following the food articles mentioned in the Ayurvedic classics. After Samsarjana it was found out that there was marked reduction in signs and symptoms in patients especially increased frequency of urination, fatigue, excessive hunger and after completion of Samsarjana Krama, previously increased FBS and PPBS came to normal range and maintained within normal limit for consecutive 3 months with Shamanoushadhi. CONCLUSION Rutu Shodhana helps to remove the embedded Doshas out of the body timely, Vasanthika Vamana does the abolishment of Kaphadosha thus helps in breakdown the Samprapti of the disease Prameha. It was observed
  • 7. Bhagyashree et al. Effective management of newly diagnosed case of Prameha ISSN: 2456-3110 CASE REPORT December 2022 Journal of Ayurveda and Integrated Medical Sciences | December 2022 | Vol. 7 | Issue 11 260 the Vasanthika Vamana showed significant effect in controlling blood glucose level and managing signs and symptoms of Prameha like Prahoota Moothrata, Ati Kshud, Galatalu Shosha, Atisweda etc. With proper Samshodhana along with Vyayama and dietary habits one can prevent and control the disease Prameha without the use of any antiglycemic agents. REFERENCES 1. DL Kasper et al. 19th edition, Harrisons Manual of medicine, Endocrinology- Diabetes mellitus, MC Graw Hill Education, 2016, P904. 2. https://www.diabetesresearchclinicalpractice.com/article/SO 168-8227(19)31230-6/fulltext. 3. Tao Z, Shi A, Zhao J. Epidemiological perspectives of diabetes, Cell Biochem Biophys 20015;73:181-5. 4. DL Kasper et al., 19th edition, Harrisons Manual of Medicine, Endocrinology - Diabetes mellitus, MC Graw Hill Education, 2016, P905-6. 5. Acharya YT (ed.), Susruta Samhita of Susruta with the Nibandhasangraha Commentary of Sri Dalhanacharya and the Nyayachandrika Panjika of Sri Gayadasacharya on Nidanastana, Nidana sthana 32nd chapter, 6th verse Varanasi: Chaukhamba Surbharati Prakashan, 2014, Pn.290. 6. Acharya YT (ed.), Charaka Samhita of Agnivesha elaborated by Charaka and Drdhabala with Ayurveda Dipika commentary by Sri Chakrapanidatta, Nidana sthana 4th chapter 7th verse, Varanasi: Chaukhamba Surbharati Prakashan, 2014, pn.212. 7. Acharya YT (ed.), Charaka Samhita of Agnivesha elaborated by Charaka and Drdhabala with Ayurveda Dipika commentary by Sri Chakrapanidatta, Nidana sthana 4th chapter 9 verse, Varanasi: Chaukhamba Surbharati Prakashan, 2014, pn.213. 8. Acharya YT (ed.), Charaka Samhita of Agnivesha elaborated by Charaka and Drdhabala with Ayurveda Dipika commentary by Sri Chakrapanidatta, Chikitsa sthana 6th chapter 15th verse, Varanasi: Chaukhamba Surbharati Prakashan, 2014, p446. 9. Acharya YT (ed.), Susruta Samhita of Susruta with the Nibandhasangraha Commentary of Sri Dalhanacharya and the Nyayachandrika Panjika of Sri Gayadasacharya on Nidanastana, Chikitsasthana 12th chapter 4th verse, Varanasi: Chaukhamba Surbharati Prakashan, 2014, P454. 10. Acharya YT (ed.), Susruta Samhita of Susruta with the Nibandhasangraha Commentary of Sri Dalhanacharya and the Nyayachandrika Panjika of Sri Gayadasacharya on Nidanastana,chikitsa sthana 11th chapter, Varanasi: Chaukhamba Surbharati Prakashan, 2014, P452. 11. Paradakara HSS (ed.), Astanga Hrdaya of Vagbhata with the commentaries Sarvangasudara of Arunadatta and Ayurvedarasayana of Hemadri, Nidanastana 10th chapter 18- 19th verse, Chaukhamba Sanskrit Samsthan, Varanasi, 2016, P504. 12. Acharya YT (ed.), Charaka Samhita of Agnivesha elaborated by Charaka and Drdhabala with Ayurveda deepika commentary by Sri Chakrapanidatta, Sutrasthana 16th chapter 21st verse, Varanasi: Choukamba Surbharati Prakashan, 2014,P97. 13. Paradakara HSS (ed.), Astanga Hrdaya of Vagbhata with the commentaries Sarvangasudara of Arunadatta and Ayurveda Rasayana of Hemadri, Sutrasthana 4th Chapter, 35th verse, Chaukhamba Sanskrit Samsthan, Varanasi, 2016, P59. ******************************* How to cite this article: Bhagyashree, Shaila Borannavar. Effective management of newly diagnosed case of Prameha with Vasanthika Vamana - A single case study. J Ayurveda Integr Med Sci 2022;11:255-260. Source of Support: Nil, Conflict of Interest: None declared. Copyright © 2022 The Author(s); Published by Maharshi Charaka Ayurveda Organization, Vijayapur (Regd). This is an open-access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by-nc-sa/4.0), which permits unrestricted use, distribution, and perform the work and make derivative works based on it only for non-commercial purposes, provided the original work is properly cited.