The document summarizes global HIV/AIDS statistics from 2011. It reports that:
1) There were approximately 34.2 million people living with HIV globally in 2011, with the majority (23.5 million) residing in Sub-Saharan Africa.
2) An estimated 2.5 million people were newly infected with HIV in 2011, with most (1.7 million) infections occurring in Sub-Saharan Africa.
3) About 1.7 million people died from AIDS-related causes in 2011, with 1.2 million deaths in Sub-Saharan Africa.
UNAIDS Global Report 2012 - Epidemiology slidesUNAIDS
The document summarizes global HIV/AIDS statistics from 2011. It finds that 34 million people were living with HIV/AIDS globally in 2011, with 2.5 million new infections and 1.7 million AIDS-related deaths that year. It also provides regional breakdowns. Regarding children under 15, it estimates 3.3 million were living with HIV, 330,000 were newly infected, and 230,000 died of AIDS-related causes in 2011.
- There were an estimated 33.3 million people living with HIV globally in 2009, with 2.6 million new HIV infections and 1.8 million AIDS-related deaths that year.
- Sub-Saharan Africa accounted for over two-thirds of people living with HIV and deaths, and over 70% of new HIV infections occurred in this region.
- An estimated 2.5 million children were living with HIV globally in 2009, with 370,000 new pediatric infections and 260,000 AIDS-related deaths among children.
Hiv aids global report 2010 - world health organizationTommy Toy
The document summarizes global statistics on HIV/AIDS in 2009:
- There were an estimated 33.3 million people living with HIV/AIDS globally in 2009.
- An estimated 2.6 million people were newly infected with HIV in 2009, including 370,000 children.
- About 1.8 million people died of AIDS-related causes in 2009, including 260,000 children.
UNAIDS World AIDS Day Report 2011 - core slides UNAIDS
- In 2010, there were an estimated 34 million people living with HIV globally, with 2.7 million new HIV infections and 1.8 million AIDS-related deaths that year.
- Sub-Saharan Africa accounted for over two-thirds of people living with HIV and over 70% of new HIV infections and AIDS deaths.
- An estimated 3.4 million children were living with HIV in 2010, with 390,000 new pediatric infections and 250,000 AIDS-related deaths among children that year.
The document summarizes global statistics on AIDS for 2008. It estimates that 33.4 million people were living with HIV/AIDS worldwide in 2008, with 2.7 million new HIV infections and 2 million AIDS-related deaths that year. Sub-Saharan Africa had the most severe epidemic, with 22.4 million people living with HIV and 1.9 million new infections. An estimated 2.1 million children under 15 were living with HIV globally.
The document summarizes global statistics on AIDS for 2008. It estimates that 33.4 million people were living with HIV/AIDS worldwide in 2008, with 2.7 million new HIV infections and 2 million AIDS-related deaths that year. Sub-Saharan Africa had the most severe epidemic, with 22.4 million people living with HIV and 1.9 million new infections. An estimated 2.1 million children under 15 were living with HIV globally.
UNAIDS Global Report 2012 - Epidemiology slidesUNAIDS
The document summarizes global HIV/AIDS statistics from 2011. It finds that 34 million people were living with HIV/AIDS globally in 2011, with 2.5 million new infections and 1.7 million AIDS-related deaths that year. It also provides regional breakdowns. Regarding children under 15, it estimates 3.3 million were living with HIV, 330,000 were newly infected, and 230,000 died of AIDS-related causes in 2011.
- There were an estimated 33.3 million people living with HIV globally in 2009, with 2.6 million new HIV infections and 1.8 million AIDS-related deaths that year.
- Sub-Saharan Africa accounted for over two-thirds of people living with HIV and deaths, and over 70% of new HIV infections occurred in this region.
- An estimated 2.5 million children were living with HIV globally in 2009, with 370,000 new pediatric infections and 260,000 AIDS-related deaths among children.
Hiv aids global report 2010 - world health organizationTommy Toy
The document summarizes global statistics on HIV/AIDS in 2009:
- There were an estimated 33.3 million people living with HIV/AIDS globally in 2009.
- An estimated 2.6 million people were newly infected with HIV in 2009, including 370,000 children.
- About 1.8 million people died of AIDS-related causes in 2009, including 260,000 children.
UNAIDS World AIDS Day Report 2011 - core slides UNAIDS
- In 2010, there were an estimated 34 million people living with HIV globally, with 2.7 million new HIV infections and 1.8 million AIDS-related deaths that year.
- Sub-Saharan Africa accounted for over two-thirds of people living with HIV and over 70% of new HIV infections and AIDS deaths.
- An estimated 3.4 million children were living with HIV in 2010, with 390,000 new pediatric infections and 250,000 AIDS-related deaths among children that year.
The document summarizes global statistics on AIDS for 2008. It estimates that 33.4 million people were living with HIV/AIDS worldwide in 2008, with 2.7 million new HIV infections and 2 million AIDS-related deaths that year. Sub-Saharan Africa had the most severe epidemic, with 22.4 million people living with HIV and 1.9 million new infections. An estimated 2.1 million children under 15 were living with HIV globally.
The document summarizes global statistics on AIDS for 2008. It estimates that 33.4 million people were living with HIV/AIDS worldwide in 2008, with 2.7 million new HIV infections and 2 million AIDS-related deaths that year. Sub-Saharan Africa had the most severe epidemic, with 22.4 million people living with HIV and 1.9 million new infections. An estimated 2.1 million children under 15 were living with HIV globally.
The document summarizes global statistics on HIV/AIDS in 2009. It states that there were 33.3 million people living with HIV/AIDS globally, with 2.6 million new infections and 1.8 million AIDS-related deaths in 2009. Sub-Saharan Africa accounted for the majority of cases, with 22.5 million people living with HIV/AIDS, 1.8 million new infections, and 1.3 million deaths. There were also 2.5 million children living with HIV/AIDS globally in 2009.
This document summarizes global HIV/AIDS statistics for 2008. It reports that there were an estimated 33.4 million people living with HIV/AIDS globally in 2008, with 2.7 million new HIV infections and 2 million AIDS-related deaths that year. It also provides breakdowns of these statistics by region and for children under 15 and adults.
Global summary of the AIDS epidemic in 2009:
- 33.3 million people were living with HIV worldwide.
- 2.6 million people were newly infected with HIV in 2009.
- 1.8 million people died of AIDS-related causes in 2009.
This document provides global statistics on the HIV/AIDS pandemic from 1990 to 2007. It details the number of people living with HIV, new HIV infections, and AIDS-related deaths each year by region. The statistics show that the HIV prevalence and number of people living with HIV have stabilized in most parts of the world except for Sub-Saharan Africa, where prevalence continues to rise. Over 7,400 new infections still occur daily worldwide, with over 96% in low and middle income countries and around 1,000 among children under 15. The document also outlines the impact of HIV/AIDS and global efforts to address the pandemic.
The document provides global statistics on the HIV/AIDS pandemic in 2007:
- 33 million people were living with HIV/AIDS globally in 2007.
- 2.7 million people were newly infected with HIV in 2007, with over 96% of infections occurring in low and middle income countries.
- 2 million people died of AIDS-related causes in 2007, with sub-Saharan Africa accounting for 1.5 million of those deaths.
This document discusses progress and challenges in combating HIV/AIDS, malaria, and tuberculosis. It notes that HIV/AIDS continues to take a heavy toll, especially in sub-Saharan Africa, where the majority of people living with HIV reside. While encouraging developments like declining infection and death rates have occurred, prevention and treatment efforts have yet to meet global targets. Malaria prevention has increased but treatment utilization remains low. Tuberculosis detection has slowed and prevalence reduction targets are unlikely to be met. Overall, the document outlines both gains and remaining gaps in the fight against three major infectious diseases.
Hiv aids global report 2010 - world health organizationTommy Toy
The document summarizes global statistics on HIV/AIDS in 2009:
- There were an estimated 33.3 million people living with HIV/AIDS globally in 2009.
- An estimated 2.6 million people were newly infected with HIV in 2009, including 370,000 children.
- About 1.8 million people died of AIDS-related causes in 2009, including 260,000 children.
Witch-hunts, where people are accused of witchcraft, remain a serious social problem in parts of Africa. Cultural beliefs that illness or misfortune can be caused by witchcraft contribute to the problem. Those accused, usually women, face violence, abandonment, or death. Poverty, jealousy, religious beliefs, and lack of legal protections also enable witch-hunts. International organizations and some countries are working to address injustices and support victims through education, legal reforms, and empowerment programs.
2008 Unaids Report Global Stats SummaryRichard Walls
This document summarizes key facts about the global AIDS epidemic in 2008. It finds that an estimated 33 million people were living with HIV worldwide in 2007. There were 2.7 million new HIV infections and 2 million AIDS-related deaths that year. Sub-Saharan Africa remains most severely affected, accounting for 22 million people living with HIV. While treatment has expanded significantly in recent years, reaching nearly 3 million people in low- and middle-income countries by the end of 2007, this only represents 31% of estimated need. Tuberculosis also remains a major killer of people with HIV due to lack of coordinated treatment efforts. The resource needs to achieve universal access to HIV treatment by 2010 were estimated at $10 billion in 2007,
This document contains epidemiological data and statistics from UNAIDS on the global HIV/AIDS epidemic in 2013. Some key points:
- An estimated 35 million people were living with HIV globally in 2013.
- There were 2.1 million new HIV infections and 1.5 million AIDS-related deaths in 2013.
- Sub-Saharan Africa accounted for the majority of people living with and affected by HIV, with 24.7 million people living with HIV in the region.
The document provides global statistics on HIV/AIDS for 2021, including:
- There were 38.4 million people living with HIV globally, with 1.7 million being children.
- There were 1.5 million new HIV infections in 2021, including 160,000 among children.
- 650,000 people died of AIDS-related illnesses in 2021, including 98,000 children.
- Sub-Saharan Africa accounted for over half of people living with HIV worldwide.
1) Zimbabwe has experienced a severe HIV/AIDS epidemic, with prevalence peaking at over 33% in the late 1990s.
2) Multiple factors contributed to the rapid spread of HIV/AIDS in Zimbabwe, including high rates of STIs, low male circumcision rates, and economic hardship.
3) Since 2000, HIV prevalence has declined significantly to 13.7% in 2010 due to robust prevention programs, increased access to treatment, and a massive cultural shift in sexual behavior.
AIDS is a global issue that has affected over 33 million people worldwide and caused over 1.8 million deaths in 2009. It is transmitted through bodily fluids and weakens the immune system. While social media has helped increase awareness of AIDS, it has also enabled the spread of misinformation and promoted high-risk sexual behavior, exacerbating the pandemic. Controlling the spread of AIDS requires education about safe sex practices and increasing access to healthcare.
The document discusses the impact of socioeconomic changes on health and healthcare systems. It notes that total health expenditures in Thailand have been rising but remain stable at around 4% of GDP. The poor previously spent a larger percentage of their income on healthcare than the rich, but this gap has narrowed. Upcoming changes like an aging population and the ASEAN Economic Community will present challenges and opportunities for Thailand's health system and services sector. Cross-cultural factors, emerging technologies, and lifestyle choices will also impact population health.
This document reports on global progress toward universal access to HIV/AIDS prevention, treatment, and care. Some key points:
- An estimated 34 million people were living with HIV globally in 2010, with sub-Saharan Africa the most affected region at 22.9 million.
- New HIV infections and AIDS-related deaths declined between 2001 and 2010, but progress needs to accelerate to achieve international targets.
- The number of people receiving antiretroviral therapy has increased substantially in low- and middle-income countries, reaching 6.65 million by the end of 2010, but coverage remains inadequate in many areas.
- Preventing mother-to-child transmission has expanded significantly, but more work
Latest UNAIDS estimates of 2.4 million people living with HIV in Europe suggest that the reported cases represent just over half of all people living with HIV in Europe. Of these an estimated 1.5 million are in Eastern Europe and central Asia. This represents a 2.5 fold increase from the 410 000 cases in 2001 and more than 10 times the number in 1991. This presentation at AIDS 2012, the XIX International AIDS Conference in Washington, DC, on 23 July 2012, discusses the reasons behind this increase and what we need to do to halt it.
This document from July 2014 contains 12 slides with data on various populations. Each slide cites sources for the data such as UNAIDS, Demographic and Health Surveys, the Centers for Disease Control and Prevention, and the World Health Organization. The slides contain statistics on topics like HIV prevalence rates, incarceration rates, and funding for HIV programs.
This document is a collection of slides from July 2014 on regional data related to HIV/AIDS. It cites sources from organizations like UNAIDS, WHO, and the South African national HIV prevalence survey from 2012. It includes data on HIV prevalence rates in high school students in South Africa as well as statistics on AIDS-related deaths exceeding indirect maternal mortality rates in several southern African countries like Botswana, South Africa, and Zambia. The document is a compilation of sources and statistics on HIV/AIDS data from various international organizations.
The document discusses efforts to end the AIDS epidemic globally. It summarizes that low- and middle-income countries are on track to reach 15 million people on antiretroviral treatment by 2015 and that 54% of eligible people in those countries were receiving treatment in 2011. It also notes that coverage of antiretroviral regimens among pregnant women living with HIV increased between 2005 and 2011 but that maternal access needs to be consistent during breastfeeding to further increase coverage and prevent new HIV infections among children.
This document summarizes findings from a review of how health insurance systems in different countries integrate and provide coverage for HIV/AIDS services. Key findings include:
- Integrating HIV services into social health insurance (SHI) systems is more challenging for low-income countries due to factors like HIV prevalence and poverty rates.
- Countries that have included HIV services in SHI tend to already have functioning health insurance systems in place. Including HIV coverage is essentially a political decision.
- Coverage can be progressively increased to include more populations, costs, and services over time, supported by external aid including HIV financing.
- Case studies of Ghana and South Africa show integration of HIV services into their SHI systems is
The document announces a town hall event hosted by UNAIDS and the International AIDS Society on July 18, 2010 at the AIDS 2010 Conference. The town hall will bring together leaders in the AIDS response to discuss reshaping the future of AIDS and moving toward universal access to HIV prevention, treatment, care and support. Guest speakers will include government officials and leaders from UNAIDS, the International AIDS Society, and other organizations.
The document summarizes global statistics on HIV/AIDS in 2009. It states that there were 33.3 million people living with HIV/AIDS globally, with 2.6 million new infections and 1.8 million AIDS-related deaths in 2009. Sub-Saharan Africa accounted for the majority of cases, with 22.5 million people living with HIV/AIDS, 1.8 million new infections, and 1.3 million deaths. There were also 2.5 million children living with HIV/AIDS globally in 2009.
This document summarizes global HIV/AIDS statistics for 2008. It reports that there were an estimated 33.4 million people living with HIV/AIDS globally in 2008, with 2.7 million new HIV infections and 2 million AIDS-related deaths that year. It also provides breakdowns of these statistics by region and for children under 15 and adults.
Global summary of the AIDS epidemic in 2009:
- 33.3 million people were living with HIV worldwide.
- 2.6 million people were newly infected with HIV in 2009.
- 1.8 million people died of AIDS-related causes in 2009.
This document provides global statistics on the HIV/AIDS pandemic from 1990 to 2007. It details the number of people living with HIV, new HIV infections, and AIDS-related deaths each year by region. The statistics show that the HIV prevalence and number of people living with HIV have stabilized in most parts of the world except for Sub-Saharan Africa, where prevalence continues to rise. Over 7,400 new infections still occur daily worldwide, with over 96% in low and middle income countries and around 1,000 among children under 15. The document also outlines the impact of HIV/AIDS and global efforts to address the pandemic.
The document provides global statistics on the HIV/AIDS pandemic in 2007:
- 33 million people were living with HIV/AIDS globally in 2007.
- 2.7 million people were newly infected with HIV in 2007, with over 96% of infections occurring in low and middle income countries.
- 2 million people died of AIDS-related causes in 2007, with sub-Saharan Africa accounting for 1.5 million of those deaths.
This document discusses progress and challenges in combating HIV/AIDS, malaria, and tuberculosis. It notes that HIV/AIDS continues to take a heavy toll, especially in sub-Saharan Africa, where the majority of people living with HIV reside. While encouraging developments like declining infection and death rates have occurred, prevention and treatment efforts have yet to meet global targets. Malaria prevention has increased but treatment utilization remains low. Tuberculosis detection has slowed and prevalence reduction targets are unlikely to be met. Overall, the document outlines both gains and remaining gaps in the fight against three major infectious diseases.
Hiv aids global report 2010 - world health organizationTommy Toy
The document summarizes global statistics on HIV/AIDS in 2009:
- There were an estimated 33.3 million people living with HIV/AIDS globally in 2009.
- An estimated 2.6 million people were newly infected with HIV in 2009, including 370,000 children.
- About 1.8 million people died of AIDS-related causes in 2009, including 260,000 children.
Witch-hunts, where people are accused of witchcraft, remain a serious social problem in parts of Africa. Cultural beliefs that illness or misfortune can be caused by witchcraft contribute to the problem. Those accused, usually women, face violence, abandonment, or death. Poverty, jealousy, religious beliefs, and lack of legal protections also enable witch-hunts. International organizations and some countries are working to address injustices and support victims through education, legal reforms, and empowerment programs.
2008 Unaids Report Global Stats SummaryRichard Walls
This document summarizes key facts about the global AIDS epidemic in 2008. It finds that an estimated 33 million people were living with HIV worldwide in 2007. There were 2.7 million new HIV infections and 2 million AIDS-related deaths that year. Sub-Saharan Africa remains most severely affected, accounting for 22 million people living with HIV. While treatment has expanded significantly in recent years, reaching nearly 3 million people in low- and middle-income countries by the end of 2007, this only represents 31% of estimated need. Tuberculosis also remains a major killer of people with HIV due to lack of coordinated treatment efforts. The resource needs to achieve universal access to HIV treatment by 2010 were estimated at $10 billion in 2007,
This document contains epidemiological data and statistics from UNAIDS on the global HIV/AIDS epidemic in 2013. Some key points:
- An estimated 35 million people were living with HIV globally in 2013.
- There were 2.1 million new HIV infections and 1.5 million AIDS-related deaths in 2013.
- Sub-Saharan Africa accounted for the majority of people living with and affected by HIV, with 24.7 million people living with HIV in the region.
The document provides global statistics on HIV/AIDS for 2021, including:
- There were 38.4 million people living with HIV globally, with 1.7 million being children.
- There were 1.5 million new HIV infections in 2021, including 160,000 among children.
- 650,000 people died of AIDS-related illnesses in 2021, including 98,000 children.
- Sub-Saharan Africa accounted for over half of people living with HIV worldwide.
1) Zimbabwe has experienced a severe HIV/AIDS epidemic, with prevalence peaking at over 33% in the late 1990s.
2) Multiple factors contributed to the rapid spread of HIV/AIDS in Zimbabwe, including high rates of STIs, low male circumcision rates, and economic hardship.
3) Since 2000, HIV prevalence has declined significantly to 13.7% in 2010 due to robust prevention programs, increased access to treatment, and a massive cultural shift in sexual behavior.
AIDS is a global issue that has affected over 33 million people worldwide and caused over 1.8 million deaths in 2009. It is transmitted through bodily fluids and weakens the immune system. While social media has helped increase awareness of AIDS, it has also enabled the spread of misinformation and promoted high-risk sexual behavior, exacerbating the pandemic. Controlling the spread of AIDS requires education about safe sex practices and increasing access to healthcare.
The document discusses the impact of socioeconomic changes on health and healthcare systems. It notes that total health expenditures in Thailand have been rising but remain stable at around 4% of GDP. The poor previously spent a larger percentage of their income on healthcare than the rich, but this gap has narrowed. Upcoming changes like an aging population and the ASEAN Economic Community will present challenges and opportunities for Thailand's health system and services sector. Cross-cultural factors, emerging technologies, and lifestyle choices will also impact population health.
This document reports on global progress toward universal access to HIV/AIDS prevention, treatment, and care. Some key points:
- An estimated 34 million people were living with HIV globally in 2010, with sub-Saharan Africa the most affected region at 22.9 million.
- New HIV infections and AIDS-related deaths declined between 2001 and 2010, but progress needs to accelerate to achieve international targets.
- The number of people receiving antiretroviral therapy has increased substantially in low- and middle-income countries, reaching 6.65 million by the end of 2010, but coverage remains inadequate in many areas.
- Preventing mother-to-child transmission has expanded significantly, but more work
Latest UNAIDS estimates of 2.4 million people living with HIV in Europe suggest that the reported cases represent just over half of all people living with HIV in Europe. Of these an estimated 1.5 million are in Eastern Europe and central Asia. This represents a 2.5 fold increase from the 410 000 cases in 2001 and more than 10 times the number in 1991. This presentation at AIDS 2012, the XIX International AIDS Conference in Washington, DC, on 23 July 2012, discusses the reasons behind this increase and what we need to do to halt it.
This document from July 2014 contains 12 slides with data on various populations. Each slide cites sources for the data such as UNAIDS, Demographic and Health Surveys, the Centers for Disease Control and Prevention, and the World Health Organization. The slides contain statistics on topics like HIV prevalence rates, incarceration rates, and funding for HIV programs.
This document is a collection of slides from July 2014 on regional data related to HIV/AIDS. It cites sources from organizations like UNAIDS, WHO, and the South African national HIV prevalence survey from 2012. It includes data on HIV prevalence rates in high school students in South Africa as well as statistics on AIDS-related deaths exceeding indirect maternal mortality rates in several southern African countries like Botswana, South Africa, and Zambia. The document is a compilation of sources and statistics on HIV/AIDS data from various international organizations.
The document discusses efforts to end the AIDS epidemic globally. It summarizes that low- and middle-income countries are on track to reach 15 million people on antiretroviral treatment by 2015 and that 54% of eligible people in those countries were receiving treatment in 2011. It also notes that coverage of antiretroviral regimens among pregnant women living with HIV increased between 2005 and 2011 but that maternal access needs to be consistent during breastfeeding to further increase coverage and prevent new HIV infections among children.
This document summarizes findings from a review of how health insurance systems in different countries integrate and provide coverage for HIV/AIDS services. Key findings include:
- Integrating HIV services into social health insurance (SHI) systems is more challenging for low-income countries due to factors like HIV prevalence and poverty rates.
- Countries that have included HIV services in SHI tend to already have functioning health insurance systems in place. Including HIV coverage is essentially a political decision.
- Coverage can be progressively increased to include more populations, costs, and services over time, supported by external aid including HIV financing.
- Case studies of Ghana and South Africa show integration of HIV services into their SHI systems is
The document announces a town hall event hosted by UNAIDS and the International AIDS Society on July 18, 2010 at the AIDS 2010 Conference. The town hall will bring together leaders in the AIDS response to discuss reshaping the future of AIDS and moving toward universal access to HIV prevention, treatment, care and support. Guest speakers will include government officials and leaders from UNAIDS, the International AIDS Society, and other organizations.
Get smart - New ways of looking at HIV data.UNAIDS
The document discusses the global HIV/AIDS epidemic, including statistics on prevalence and numbers of people living with HIV in different countries and populations. It notes that prevalence and transmission modes vary significantly in different locations. Charts show trends in new infections, prevalence among women, and potential for virtual elimination of mother-to-child transmission.
The last 100 hiv infections (UNAIDS OUTLOOK report 2010)UNAIDS
One way countries are adapting is by using data to follow the source of new infections, or ‘modes of transmission’, and then basing HIV prevention programmes on the evidence they find.
This document shows estimates of new HIV infections in the United States from 1977 to 2006 broken down by transmission category. The majority of infections were among men who have sex with men, followed by injecting drug use, and a combination of men who have sex with men and injecting drug use. A smaller number of infections were attributed to heterosexual transmission. The estimates are based on an extended back calculation model that specified periods where the number of HIV infections was assumed to remain constant.
This document shows estimates of new HIV infections in the United States from 1977 to 2006 broken down by transmission category. The majority of infections were among men who have sex with men, with injecting drug use and heterosexual transmission also contributing to infection rates. Infection estimates remained highest among men who have sex with men throughout the entire time period.
This document provides an overview of key issues related to the global HIV/AIDS epidemic and response in 2010. It highlights statistics on new HIV infections and people living with HIV globally and by region. It also discusses progress towards universal access to HIV prevention, treatment, care and support. The document outlines UNAIDS' priority areas and provides case studies on efforts to scale up access to antiretroviral therapy through programs like the Global Fund. It also explores innovations in HIV prevention and ideas to strengthen the overall AIDS response.
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Cell Therapy Expansion and Challenges in Autoimmune DiseaseHealth Advances
There is increasing confidence that cell therapies will soon play a role in the treatment of autoimmune disorders, but the extent of this impact remains to be seen. Early readouts on autologous CAR-Ts in lupus are encouraging, but manufacturing and cost limitations are likely to restrict access to highly refractory patients. Allogeneic CAR-Ts have the potential to broaden access to earlier lines of treatment due to their inherent cost benefits, however they will need to demonstrate comparable or improved efficacy to established modalities.
In addition to infrastructure and capacity constraints, CAR-Ts face a very different risk-benefit dynamic in autoimmune compared to oncology, highlighting the need for tolerable therapies with low adverse event risk. CAR-NK and Treg-based therapies are also being developed in certain autoimmune disorders and may demonstrate favorable safety profiles. Several novel non-cell therapies such as bispecific antibodies, nanobodies, and RNAi drugs, may also offer future alternative competitive solutions with variable value propositions.
Widespread adoption of cell therapies will not only require strong efficacy and safety data, but also adapted pricing and access strategies. At oncology-based price points, CAR-Ts are unlikely to achieve broad market access in autoimmune disorders, with eligible patient populations that are potentially orders of magnitude greater than the number of currently addressable cancer patients. Developers have made strides towards reducing cell therapy COGS while improving manufacturing efficiency, but payors will inevitably restrict access until more sustainable pricing is achieved.
Despite these headwinds, industry leaders and investors remain confident that cell therapies are poised to address significant unmet need in patients suffering from autoimmune disorders. However, the extent of this impact on the treatment landscape remains to be seen, as the industry rapidly approaches an inflection point.
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2. Global summary of the AIDS epidemic 2011
Number of people Total 34.2 million [31.8 million–35.9 million]
living with HIV Adults 30.7 million [28.6 million–32.2 million]
Women 16.7 million [15.7 million–17.8 million]
Children (<15 years) 3.4 million [3.1 million–3.9 million]
People newly infected Total 2.5 million [2.2 million–2.8 million]
with HIV in 2011 Adults 2.2 million [2.0 million–2.4 million]
Children (<15 years) 330 000 [280 000–380 000]
AIDS deaths in 2011 Total 1.7 million [1.6 million–1.9 million]
Adults 1.5 million [1.3 million–1.7 million]
Children (<15 years) 230 000 [200 000–270 000]
3. Global estimates for adults and children 2011
People living with HIV 34.2 million [31.8 million – 35.9 million]
New HIV infections in 2011 2.5 million [2.2 million – 2.8 million]
Deaths due to AIDS in 2011 1.7 million [1.6 million – 1.9 million]
4. Regional HIV and AIDS statistics and features 2011
Adults and children Adults and children Adult prevalence Adult & child
living with HIV newly infected with HIV (15‒ 49) [%] deaths due to AIDS
Sub-Saharan Africa 23.5 million 1.7 million 4.8% 1.2 million
[22.2 million – 24.7 million] [1.6 million – 1.9 million] [4.6% – 5.1%] [1.1 million – 1.3 million]
Middle East and North Africa 330 000 39 000 0.2% 25 000
[250 000 – 450 000] [29 000 – 60 000] [0.1% – 0.2%] [17 000 – 35 000]
South and South-East Asia 4.2 million 300 000 0.3% 270 000
[3.1 million – 4.7 million] [220 000 – 340 000] [0.2% – 0.4%] [140 000 – 600 000]
East Asia 830 000 89 000 0.1% 60 000
[590 000 – 1.2 million] [44 000 – 170 000] [0.1% – 0.1%] [42 000 – 83 000]
Latin America 1.4 million 86 000 0.4% 57 000
[1.1 million – 1.7 million] [52 000 – 140 000] [0.3% – 0.5%] [35 000 – 86 000]
Caribbean 230 000 13 000 1.0% 10 000
[200 000 – 250 000] [9700 – 16 000] [0.8% – 1.1%] [8200 – 12 000]
Eastern Europe and Central Asia 1.5 million 170 000 1.0% 90 000
[1.3 million – 1.8 million] [110 000 – 220 000] [0.8% – 1.1%] [74 000 – 110 000]
Western and Central Europe 860 000 30 000 0.2% 9300
[780 000 – 960 000] [21 000 – 40 000] [0.2% – 0.2%] [8300 – 10 000]
North America 1.4 million 58 000 0.6% 20 000
[1.1 million – 2.0 million] [21 000 – 130 000] [0.5% – 1.0%] [16 000 – 27 000]
Oceania 53 000 2900 0.3% 1300
[47 000 – 60 000] [2200 – 3800] [0.2% – 0.3%] [<1000 – 1800]
TOTAL 34.2 million 2.5 million 0.8% 1.7 million
[31.8 million – 35.9 million] [2.2 million – 2.8 million] [0.7% - 0.8%] [1.6 million – 1.9 million]
The ranges around the estimates in this table define the boundaries within which the actual numbers lie, based on the best available information.
5. Adults and children estimated to be living with HIV 2011
Western & Eastern Europe
Central Europe & Central Asia
860 000 1.5 million
North America [780 000 – 960 000] [1.3 million – 1.8 million]
1.4 million East Asia
[1.1 million – 2.0 million] 830 000
Middle East & North Africa [590 000 – 1.2 million]
Caribbean 330 000
230 000 [250 000 – 450 000] South & South-East Asia
[200 000 – 250 000] 4.2 million
Sub-Saharan Africa [3.1 million – 4.7 million]
Latin America 23.5 million
1.4 million [22.2 million – 24.7 million] Oceania
[1.1 million – 1.7 million] 53 000
[47 000 – 60 000]
Total: 34.2 million [31.8 million – 35.9 million]
6. Estimated number of adults and children
newly infected with HIV 2011
Western & Eastern Europe
Central Europe & Central Asia
30 000 170 000
North America [21 000 – 40 000] [110 000 – 220 000]
58 000 East Asia
[21 000 – 130 000] 89 000
[44 000 – 170 000]
Middle East & North Africa
Caribbean 39 000
13 000 [29 000 – 60 000] South & South-East Asia
[9700 – 16 000] 300 000
Sub-Saharan Africa [220 000 – 340 000]
Latin America 1.7 million
86 000 [1.6 million – 1.9 million] Oceania
[52 000 – 140 000] 2900
[2200 – 3800]
Total: 2.5 million [2.2 million – 2.8 million]
7. Estimated adult and child deaths from AIDS 2011
Western & Eastern Europe
Central Europe & Central Asia
9300 90 000
North America [8300 – 10 000] [74 000 – 110 000]
20 000 East Asia
[16 000 – 27 000] 60 000
Middle East & North Africa [42 000 – 83 000]
Caribbean 25 000
10 000 [17 000 – 35 000] South & South-East Asia
[8200 – 12 000] 270 000
Sub-Saharan Africa [140 000 – 600 000]
Latin America 1.2 million
57 000 [1.1 million – 1.3 million] Oceania
[35 000 – 86 000] 1300
[<1000 – 1800]
Total: 1.7 million [1.6 million – 1.9 million]
8. Children (<15 years) estimated to be living with HIV 2011
Western & Eastern Europe
Central Europe & Central Asia
1800 17 000
North America [1400 – 2100] [14 000 – 21 000]
4500 East Asia
[4000 – 5800] 16 000
Middle East & North Africa [11 000 – 22 000]
Caribbean 19 000
18 000 [12 000 – 26 000] South & South-East Asia
[15 000 – 21 000] 180 000
Sub-Saharan Africa [100 000 – 230 000]
Latin America 3.1 million
40 000 [2.8 million – 3.4 million] Oceania
[29 000 – 54 000] 3600
[2800 – 4600]
Total: 3.4 million [3.1 million – 3.9 million]
9. Estimated number of children (<15 years)
newly infected with HIV 2011
Western & Eastern Europe
Central Europe & Central Asia
<200 1700
North America [<200] [1400 – 2200]
<100 East Asia
[<200] 2000
Middle East & North Africa [<1000 – 4100]
Caribbean 3100
1100 [2100 – 4500] South & South-East Asia
[<1000 – 1400] 21 000
Sub-Saharan Africa [14 000 – 27 000]
Latin America 300 000
2000 [250 000 – 350 000] Oceania
[<1000 – 3900] <500
[<200 – <500]
Total: 330 000 [280 000 – 380 000]
10. Estimated deaths in children (<15 years) from AIDS 2011
Western & Eastern Europe
Central Europe & Central Asia
<100 1100
North America [<100 - <200] [<1000 – 1500]
<100 East Asia
[<200] 1100
Middle East & North Africa [<1000 – 1700]
Caribbean 1800
1100 [1200 – 2600] South & South-East Asia
[<1000 – 1400] 15 000
Sub-Saharan Africa [9800 – 17 000]
Latin America 210 000
2200 [180 000 – 240 000] Oceania
[1100 – 3700] <500
[<200 – <500]
Total: 230 000 [200 000 – 270 000]
11. Over 7000 new HIV infections a day in 2011
About 97% are in low and middle income countries
About 900 are in children under 15 years of age
About 6000 are in adults aged 15 years and older, of whom:
─ almost 47% are among women
─ about 41% are among young people (15-24)
12. 2011 global HIV and AIDS estimates
Children (<15 years)
Children living with HIV 3.4 million [3.1 million – 3.9 million]
New HIV infections in 2011 330 000 [280 000 – 380 000]
Deaths due to AIDS in 2011 230 000 [200 000 – 270 000]