13. Your patient is going into a coma. Give the mechanism for a patient to go into a coma for the patient with uremia. Mechanism for coma in uremia: 14. Systemic hypotension may develop in patients with renal failure. Give specific CAUSE for SY STEMIC HYPOTENSION to develop in renal failure. Cause of systemic hypotension in renal failure: Mechanism for systemic hypotension in renal failure: 15. Bleeding tendencies may develop in patients with renal failure. Give the mechanism for the development of bleeding tendencies in renal failure. Mechanism:.