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Urologic Disorders
Abdulaziz Althunayan
Consultant Urologist
Assistant professor of Surgery
Urologic Disorders
Urinary tract infections
Urolithiasis
Benign Prostatic Hyperplasia and voiding
dysfunction
Urinary tract infections
Urethritis
Epididymitis/orchitis
Prostatitis
cystitis
Acute Pyelonephritis
Chronic Pyelonephritis
Renal Abscess
URETHRITIS
S&S
– urethral discharge
– burning on urination
– Asymptomatic
Gonococcal vs. Nongonococcal
DX:
– incubation period(3-10 days vs. 1-5 wks)
– Urethral swab
– Serum: Chlamydia-specific ribosomal RNA
URETHRITIS
Epididymitis
Acute : pain, swelling, of the epididymis <6wk
chronic :long-standing pain in the epididymis and
testicle, usu. no swelling.
DX
– Epididymitis vs. Torsion
– U/S
– Testicular scan
– Younger : N. gonorrhoeae or C. trachomatis
– Older : E. coli
Epididymitis
Prostatitis
Syndrome that presents with inflammation±
infection of the prostate gland including:
– Dysuria, frequency
– dysfunctional voiding
– Perineal pain
– Painful ejaculation
Prostatitis
Prostatitis
Acute Bacterial Prostatitis :
– Rare
– Acute pain
– Storage and voiding urinary symptoms
– Fever, chills, malaise, N/V
– Perineal and suprapubic pain
– Tender swollen hot prostate.
– Rx : Abx and urinary drainage
cystitis
S&S:
– dysuria, frequency, urgency, voiding of small
urine volumes,
– Suprapubic /lower abdominal pain
– ± Hematuria
– DX:
dip-stick
urinalysis
Urine culture
Pyelonephritis
Inflammation of the kidney and renal pelvis
S&S :
– Chills
– Fever
– Costovertebral angle tenderness (flank Pain)
– GI:abdo pain, N/V, and diarrhea
– Gr-ve sepsis
– Dysuria, frequency
Pyelonephritis
Investigation:
– Urine C&S :+VE(80%)
Enterobacteriaceae (E. coli), Enterococcus
– Urinalysis:↑ WBCs, RBCs,Bacteria
– (±) ↑serum Creatinine
– CBC : Leukocytosis
Pyelonephritis
Imaging:
– IVP
– U/S
– CT
Urolithiasis
Egyptian mummies
4800 BC
Prevalence of 2% to
3%,
Life time risk: Male :
20%, female 5-10%
Recurrence rate 50% at
10 years
Urolithiasis
Risk factors:
– Intrinsic Factors
Genetics
Age (2Os-4Os)
Sex M>F
Urolithiasis
Extrinsic Factors
– Geography (mountainous, desert, tropics )
– Climate (July - October)
– Water Intake
– Diet (purines , oxalates, Na )
– Occupation (sedentary occupations )
Urolithiasis
How do stones form
– supersaturated→ Crystal Growth
– Aggregation of crystals →stone
Urolithiasis
Most people have crystals in their urine, so why
not everyone gets stones?
– Anatomic abnormalities
– Modifiers of crystal formation: Inhibitors/promoters
Citrate
Mg,
urinary proteins(nephrocalcin)
oxalate
Urolithiasis
Common stone types
– Calcium stones 75%
(ca Ox )
– Uric acid stones
– Cystine stones
– Struvite stones
Urolithiasis
S&S
– Renal or ureteric colic
– Freq, dysuria
– Hematuria
– GI symptoms: N/V, ileus, or
diarrhea
– DDx :
Gastroenteritis
acute appendicitis
colitis
salpingitis
Urolithiasis
Cont. S&S
– Restless
↑HR, ↑ BP
fever (If UTI)
Tender CVA
Urolithiasis
Investigation
Urinalysis :
– RBC
– WBC
– Bacteria
– Crystals
Urolithiasis
Investigation
Imaging
– Plain Abdominal Films (KUB)
– Intravenous Urography (IVP)
– Ultrasonography (U/S)
– Computed Tomography (CT)
Urolithiasis
Management
Conservative
– Hydration
– Analgesia
– Antiemetic
– Stones (<5mm ) >90% spontaneous Passage
Indication for admission
– Renal impairment
– Refractory pain
– Pyelonephritis
– intractable N/V
Urolithiasis
Management
Extracorporeal Shock Wave lithotripsy (SWL)
Ureteroscopy
Percutaneous Nephrolithotripsy (PNL)
Open Sx
Extracorporeal Shock Wave
lithotripsy ( SWL)
Ureteroscopy
Ureteroscopy: Laser
Percutaneous Nephrolithotripsy (PNL)
Voiding Dysfunction
Voiding Dysfunction
Failure to store
– Bladder problems
overactivity
Hypersensitivity
– Outlet problem
Stress incontinence
Sphincter deficiency
– combination
Failure to Empty
– Bladder problems
Neurologic
Myogenic
idiopathic
– Outlet problem
BPH
Urethral stricture
Sphincter dyssynergia
– combination
Over Active Bladder
Benign Prostatic Hyperplasia
BPH
Clinically:
– LUTS
– poor bladder emptying
– urinary retention
– urinary tract infection
– Hematuria
– Renal insufficiency
Benign Prostatic Hyperplasia
Physical Examination
– 1-DRE 2- Focused
neurologic exam
Prostate Ca
rectal Ca
anal tone
neurologic problems
– Abdomen: distended
bladder
Benign Prostatic Hyperplasia
Urinalysis , culture
– UTI
– Hematuria
Serum Creatinine
Serum Prostate-Specific Antigen
Flow rate
Ultrasound (Kidney, Bladder And Prostate)
Benign Prostatic Hyperplasia
Treatment options
– medical therapy
α-Adrenergic Blockers
– Tamsulocin
– Alfuzocin
– Terazocin
Androgen Suppression
– Finasteride
Benign Prostatic Hyperplasia
Surgical Rx
– Endoscopic
– Transurethral Resection of the
Prostate TURP
– Laser ablation
– prostatic stents
Open Prostatectomy

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10- Urological Diorders .ppt