10 1 = 3. 6 7 8 10 11) 12 RNA, and protein is made daring this period, therefore, it is 2 petiod when metabolic activity Propbase. In rhis phase, which is the first observable stage of cell division at a microscopicle cach chromosome becomes visible as two identical chromatids moving toward the center of the cell is at its greatest. cell. The centrioles separatc, begin to move apart, and spindle fibers extend from one cent to the other. The nucleolus is no longer evident, and the nuclear envelope begins to fragmen Prometapbase. This stage is the first part of metaphase. The spindle becomes larger, ar centrioles are clearly visible at its poles. The chromosomes move toward the center of the Metaphase. At this time the doublestranded chromosomes align at the center of the nuch the spindle fibers can be seen attached to the centromeres. The array of chromosomes A napbase. During this phase the chromosomes, which are now single stranded due to th to the spindle is called the equatorial plate. of the centromere, move toward opposite poles of the cell..