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3. FORT WORTH/DALLAS M.D. NEWS NOVEMBER 2008 | 1
VOL. 16, NO. 9contents
4 COVER STORY
BAYLOR ALL SAINTS:
ON THE FOREFRONT OF
PANCREATIC ISLET CELL
TRANSPLANTATION
RESEARCH
Worldwide research is being done on this
complex procedure in which islets are
taken from the pancreas of a nonliving
organ donor, purified, processed and
then transferred into the diabetic’s liver.
The beta cells begin to make and release
insulin once implanted, assuming the role
of a backup pancreas. The most effective
research stands on the shoulders of giants
and the researchers as Baylor works
closely with other scientists to achieve the
most beneficial data possible.
10 FEATURE
GERIATRIC UPDATE
A look at the issues, concerns and diseases
that affect the elderly and their caregivers
ON THE COVER
(Left to right) Marlon Levy, M.D., Surgical
Director of Transplantation at Baylor All
Saints Medical Center and Medical Director
of the Islet Cell Program, and Shinichi
Matsumoto, M.D., Ph.D., Director, All
Saints Islet Cell Research and Director,
Baylor Institute for Immunology Research
Islet Cell Transplantation Research
NOVEMBER 2008
DEPARTMENTS
2 from the publisher
3 news
7 adventure
8 restaurant review
14 perspective
24 news
4
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16 SPECIAL FEATURE
THE TEXAS CLINIC AT
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ON THE COVER
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ON THE COVER
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GERIATRIC
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GERIATRIC UPDATE
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UPDATE
A look at the issues, concerns and diseases© 2008 SUNSHINE MEDIA,INC.UNAUTHORIZED USE OFTHIS DOCUMENT IS STRICTLY PROHIBITED.
A look at the issues, concerns and diseases
review
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review
perspective
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perspective
24
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4. 2 | FORT WORTH/DALLAS M.D. NEWS NOVEMBER 2008
Hello again,
Overthepastyears,M.D.Newshascirculatedourcoverstoryand
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ketingandpublicrelationsdirectorsaswellasothersinthemedical
community. This form allows for recognition for many deserving
areaphysiciansthatareontheforefrontofmedicaladvances,surgical
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5. FORT WORTH/DALLAS M.D. NEWS NOVEMBER 2008 | 3
Baylor Health Care System Breaks Ground on
New Baylor Medical Center at McKinney
McKinney Development to be Baylor’s Fourth Hospital in Collin County
news
On Tuesday, September 23, Baylor
Health Care System will break ground
on 332,000-square-foot Baylor Medical
Center at McKinney, located on 58 acres
at the northwest corner of Highway 380
and Lake Forest Drive. Baylor will host
a groundbreaking at 10 a.m. Health care
system officials anticipate completion of
the estimated $212-million, 95-bed, four-
story hospital and medical office complex
by November 2010.
Services at the medical center will
include obstetrics and gynecology; gen-
eralsurgery;cardiovascularcareincluding
cardiac catheterization; gastroenterology,
including endoscopy services; orthopae-
dics;neurologyandneurosurgery;internal
medicine;afull-serviceemergencydepart-
ment and extensive outpatient services.
“The health care services provided by
this new hospital will meet the increasing
medicalneedsofthiscommunity,”saysJoel
Allison, President and CEO, Baylor Health
CareSystem.“Welookforwardtobuilding
what will prove to be an innovative facility
offering exemplary health care for the resi-
dents of McKinney, close to their homes.”
ThepopulationofMcKinneyandthesur-
rounding area is expected to grow 34.5%
between 2006 and 2011. According to the
mostrecentcensusdata(releasedMarch21,
2007), Collin County is the eighth fastest
growingcountyinthenationinnumbersof
people. In fact, Collin County is growing
faster than Denton and Dallas counties. As
thecommunitygrows,Baylorplanstogrow
withit.Theinfrastructureofthemainhos-
pitalwillbebuilttoaccommodateatotalof
12 floors and more than 400 beds.
“Baylor has a longstanding tradition
of partnering with physicians to provide
quality patient care,” says Michael Taylor,
Senior Vice President, Baylor. “We have
been working with a core group of physi-
cians and a clinical design team for the
past 12 months on an innovative design
that incorporates the latest advances in
information technology and supports our
commitment to quality.” Physician prac-
tices will be located in an adjacent medical
office building. ■
RR
dics;neurologyandneurosurgery;internal
R
dics;neurologyandneurosurgery;internal
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including endoscopy services; orthopae-
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including endoscopy services; orthopae-
dics;neurologyandneurosurgery;internal
E
dics;neurologyandneurosurgery;internal
VV
eralsurgery;cardiovascularcareincluding
V
eralsurgery;cardiovascularcareincluding
cardiac catheterization; gastroenterology,
V
cardiac catheterization; gastroenterology,
including endoscopy services; orthopae-
V
including endoscopy services; orthopae-
dics;neurologyandneurosurgery;internal
V
dics;neurologyandneurosurgery;internal
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I
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cardiac catheterization; gastroenterology,
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including endoscopy services; orthopae-
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dics;neurologyandneurosurgery;internal
Idics;neurologyandneurosurgery;internal
growingcountyinthenationinnumbersof
Igrowingcountyinthenationinnumbersof
people. In fact, Collin County is growing
Ipeople. In fact, Collin County is growing
E
rounding area is expected to grow 34.5%
E
rounding area is expected to grow 34.5%
between 2006 and 2011. According to the
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between 2006 and 2011. According to the
mostrecentcensusdata(releasedMarch21,
E
mostrecentcensusdata(releasedMarch21,
2007), Collin County is the eighth fastest
E2007), Collin County is the eighth fastest
growingcountyinthenationinnumbersof
Egrowingcountyinthenationinnumbersof
people. In fact, Collin County is growing
Epeople. In fact, Collin County is growingW
dents of McKinney, close to their homes.”
W
dents of McKinney, close to their homes.”
ThepopulationofMcKinneyandthesur-
W
ThepopulationofMcKinneyandthesur-
rounding area is expected to grow 34.5%
W
rounding area is expected to grow 34.5%
between 2006 and 2011. According to the
W
between 2006 and 2011. According to the
mostrecentcensusdata(releasedMarch21,
Wmostrecentcensusdata(releasedMarch21,
2007), Collin County is the eighth fastest
W2007), Collin County is the eighth fastest
growingcountyinthenationinnumbersof
Wgrowingcountyinthenationinnumbersof
people. In fact, Collin County is growingWpeople. In fact, Collin County is growing
O
offering exemplary health care for the resi-
O
offering exemplary health care for the resi-
dents of McKinney, close to their homes.”
O
dents of McKinney, close to their homes.”
ThepopulationofMcKinneyandthesur-
OThepopulationofMcKinneyandthesur-
rounding area is expected to grow 34.5%
Orounding area is expected to grow 34.5%
between 2006 and 2011. According to the
Obetween 2006 and 2011. According to the
quality patient care,” says Michael Taylor,
O
quality patient care,” says Michael Taylor,
Senior Vice President, Baylor. “We have
O
Senior Vice President, Baylor. “We have
been working with a core group of physi-
O
been working with a core group of physi-
cians and a clinical design team for the
Ocians and a clinical design team for the
past 12 months on an innovative design
Opast 12 months on an innovative design
that incorporates the latest advances in
Othat incorporates the latest advances in
information technology and supports ourOinformation technology and supports our
N
of partnering with physicians to provide
N
of partnering with physicians to provide
quality patient care,” says Michael Taylor,
N
quality patient care,” says Michael Taylor,
Senior Vice President, Baylor. “We have
N
Senior Vice President, Baylor. “We have
been working with a core group of physi-
Nbeen working with a core group of physi-
cians and a clinical design team for the
Ncians and a clinical design team for the
past 12 months on an innovative design
Npast 12 months on an innovative design
L
“Baylor has a longstanding tradition
L
“Baylor has a longstanding tradition
of partnering with physicians to provide
L
of partnering with physicians to provide
quality patient care,” says Michael Taylor,
Lquality patient care,” says Michael Taylor,
Senior Vice President, Baylor. “We have
LSenior Vice President, Baylor. “We have
been working with a core group of physi-
Lbeen working with a core group of physi-
cians and a clinical design team for theLcians and a clinical design team for the
Y
pitalwillbebuilttoaccommodateatotalof
Y
pitalwillbebuilttoaccommodateatotalof
Y
12 floors and more than 400 beds.
Y
12 floors and more than 400 beds.
“Baylor has a longstanding tradition
Y
“Baylor has a longstanding tradition
of partnering with physicians to provide
Yof partnering with physicians to provide
quality patient care,” says Michael Taylor,
Yquality patient care,” says Michael Taylor,
Senior Vice President, Baylor. “We have
YSenior Vice President, Baylor. “We have
been working with a core group of physi-Ybeen working with a core group of physi-
LYL
“Baylor has a longstanding tradition
L
“Baylor has a longstanding tradition
Y
“Baylor has a longstanding tradition
L
“Baylor has a longstanding tradition
of partnering with physicians to provide
L
of partnering with physicians to provide
Yof partnering with physicians to provide
L
of partnering with physicians to provide
quality patient care,” says Michael Taylor,
Lquality patient care,” says Michael Taylor,
Yquality patient care,” says Michael Taylor,
Lquality patient care,” says Michael Taylor,
Senior Vice President, Baylor. “We have
LSenior Vice President, Baylor. “We have
YSenior Vice President, Baylor. “We have
LSenior Vice President, Baylor. “We have
been working with a core group of physi-
Lbeen working with a core group of physi-Ybeen working with a core group of physi-
Lbeen working with a core group of physi-
© 2008 SUNSHINE MEDIA,INC.UNAUTHORIZED USE OFTHIS DOCUMENT IS STRICTLY PROHIBITED.been working with a core group of physi-
© 2008 SUNSHINE MEDIA,INC.UNAUTHORIZED USE OFTHIS DOCUMENT IS STRICTLY PROHIBITED.been working with a core group of physi-
cians and a clinical design team for the
© 2008 SUNSHINE MEDIA,INC.UNAUTHORIZED USE OFTHIS DOCUMENT IS STRICTLY PROHIBITED.
cians and a clinical design team for the
past 12 months on an innovative design
© 2008 SUNSHINE MEDIA,INC.UNAUTHORIZED USE OFTHIS DOCUMENT IS STRICTLY PROHIBITED.
past 12 months on an innovative design
© 2008 SUNSHINE MEDIA,INC.UNAUTHORIZED USE OFTHIS DOCUMENT IS STRICTLY PROHIBITED.
© 2008 SUNSHINE MEDIA,INC.UNAUTHORIZED USE OFTHIS DOCUMENT IS STRICTLY PROHIBITED.
2007), Collin County is the eighth fastest
© 2008 SUNSHINE MEDIA,INC.UNAUTHORIZED USE OFTHIS DOCUMENT IS STRICTLY PROHIBITED.
2007), Collin County is the eighth fastest
growingcountyinthenationinnumbersof
© 2008 SUNSHINE MEDIA,INC.UNAUTHORIZED USE OFTHIS DOCUMENT IS STRICTLY PROHIBITED.
growingcountyinthenationinnumbersof
people. In fact, Collin County is growing
© 2008 SUNSHINE MEDIA,INC.UNAUTHORIZED USE OFTHIS DOCUMENT IS STRICTLY PROHIBITED.
people. In fact, Collin County is growing
that incorporates the latest advances in
© 2008 SUNSHINE MEDIA,INC.UNAUTHORIZED USE OFTHIS DOCUMENT IS STRICTLY PROHIBITED.
that incorporates the latest advances in
information technology and supports our
© 2008 SUNSHINE MEDIA,INC.UNAUTHORIZED USE OFTHIS DOCUMENT IS STRICTLY PROHIBITED.
information technology and supports our
commitment to quality.” Physician prac-
© 2008 SUNSHINE MEDIA,INC.UNAUTHORIZED USE OFTHIS DOCUMENT IS STRICTLY PROHIBITED.
commitment to quality.” Physician prac-
6. 4 | FORT WORTH/DALLAS M.D. NEWS NOVEMBER 2008
cover
story
The future holds remarkable promise for patients with
type 1 diabetes, and the physician scientists at Baylor
Research Institute are striving to seize that promise as they
not only make advances in the management of this disease,
but also push to find a cure. In March 2006, Baylor Dallas
became the first center in Texas to receive FDA permission
to independently process pancreatic
islet cell for transplantation, a prom-
ising experimental procedure on
which they are currently conducting
research and clinical trials, and have
continued to make great strides.
COLLABORATION
Worldwide research is being done
on this complex procedure in which
islets are taken from the pancreas of
a nonliving organ donor, purified,
processed and then transferred into
the diabetic’s liver. The beta cells
begin to make and release insulin
once implanted, assuming the role of
a backup pancreas. The most effective
research stands on the shoulders of
giants, and the researchers at Baylor
works closely with other scientists
to achieve the most beneficial data
possible. “We were very excited
about the results as described by the
Edmonton protocol, and when we
started our program a collaboration
was developed with the Canadian
group to further the research and
its implementation,” says Marlon
Levy, M.D., Surgical Director of
Liver,KidneyandPancreasTransplant
Baylor All Saints: On the
Forefront of Pancreatic Islet Cell
Transplantation ResearchBy Jeanie Erwin
“Ultimately, this program will focus on finding cures for diabetes, not only type 1, but also
type 2. With improved efficacy and reduced side effects of islet transplantation, we will
perform a lot of this treatment to the diabetic patients. Currently, there are approximately 20
million diabetic patients in the United States. Advanced research should reduce this number
significantly,” says Marlon Levy, M.D., Surgical Director of Transplantation at Baylor All
Saints Medical Center and Medical Director of the Islet Cell Program.
RREVV
Saints Medical Center and Medical Director of the Islet Cell Program.
V
Saints Medical Center and Medical Director of the Islet Cell Program.
II
Marlon Levy, M.D., Surgical Director of Transplantation at Baylor All
I
Marlon Levy, M.D., Surgical Director of Transplantation at Baylor All
Saints Medical Center and Medical Director of the Islet Cell Program.
I
Saints Medical Center and Medical Director of the Islet Cell Program.
E
perform a lot of this treatment to the diabetic patients. Currently, there are approximately 20
E
perform a lot of this treatment to the diabetic patients. Currently, there are approximately 20
million diabetic patients in the United States. Advanced research should reduce this number
E
million diabetic patients in the United States. Advanced research should reduce this number
EE
Marlon Levy, M.D., Surgical Director of Transplantation at Baylor All
E
Marlon Levy, M.D., Surgical Director of Transplantation at Baylor All
Saints Medical Center and Medical Director of the Islet Cell Program.
ESaints Medical Center and Medical Director of the Islet Cell Program.
W
“Ultimately, this program will focus on finding cures for diabetes, not only type 1, but also
W
“Ultimately, this program will focus on finding cures for diabetes, not only type 1, but also
type 2. With improved efficacy and reduced side effects of islet transplantation, we will
W
type 2. With improved efficacy and reduced side effects of islet transplantation, we will
perform a lot of this treatment to the diabetic patients. Currently, there are approximately 20
W
perform a lot of this treatment to the diabetic patients. Currently, there are approximately 20
million diabetic patients in the United States. Advanced research should reduce this number
W
million diabetic patients in the United States. Advanced research should reduce this number
WWMarlon Levy, M.D., Surgical Director of Transplantation at Baylor All
WMarlon Levy, M.D., Surgical Director of Transplantation at Baylor All
Saints Medical Center and Medical Director of the Islet Cell Program.
WSaints Medical Center and Medical Director of the Islet Cell Program.
O
became the first center in Texas to receive FDA permission
O
became the first center in Texas to receive FDA permission
to independently process pancreatic
O
to independently process pancreatic
islet cell for transplantation, a prom-
Oislet cell for transplantation, a prom-
ising experimental procedure on
Oising experimental procedure on
which they are currently conducting
Owhich they are currently conducting
perform a lot of this treatment to the diabetic patients. Currently, there are approximately 20
Operform a lot of this treatment to the diabetic patients. Currently, there are approximately 20 N
but also push to find a cure. In March 2006, Baylor Dallas
N
but also push to find a cure. In March 2006, Baylor Dallas
became the first center in Texas to receive FDA permission
N
became the first center in Texas to receive FDA permission
to independently process pancreatic
Nto independently process pancreatic
islet cell for transplantation, a prom-
Nislet cell for transplantation, a prom-
ising experimental procedure on
Nising experimental procedure on
L
not only make advances in the management of this disease,
L
not only make advances in the management of this disease,
but also push to find a cure. In March 2006, Baylor Dallas
L
but also push to find a cure. In March 2006, Baylor Dallas
became the first center in Texas to receive FDA permission
Lbecame the first center in Texas to receive FDA permission
to independently process pancreatic
Lto independently process pancreatic
islet cell for transplantation, a prom-Lislet cell for transplantation, a prom-
Y
not only make advances in the management of this disease,
Y
not only make advances in the management of this disease,
but also push to find a cure. In March 2006, Baylor Dallas
Ybut also push to find a cure. In March 2006, Baylor Dallas
became the first center in Texas to receive FDA permission
Ybecame the first center in Texas to receive FDA permission
to independently process pancreatic
Yto independently process pancreatic
LYL
not only make advances in the management of this disease,
L
not only make advances in the management of this disease,
Y
not only make advances in the management of this disease,
L
not only make advances in the management of this disease,
but also push to find a cure. In March 2006, Baylor Dallas
L
but also push to find a cure. In March 2006, Baylor Dallas
Ybut also push to find a cure. In March 2006, Baylor Dallas
L
but also push to find a cure. In March 2006, Baylor Dallas
became the first center in Texas to receive FDA permission
Lbecame the first center in Texas to receive FDA permission
Ybecame the first center in Texas to receive FDA permission
Lbecame the first center in Texas to receive FDA permission
to independently process pancreatic
Lto independently process pancreatic
Yto independently process pancreatic
Lto independently process pancreatic
© 2008 SUNSHINE MEDIA,INC.UNAUTHORIZED USE OFTHIS DOCUMENT IS STRICTLY PROHIBITED.to independently process pancreatic
© 2008 SUNSHINE MEDIA,INC.UNAUTHORIZED USE OFTHIS DOCUMENT IS STRICTLY PROHIBITED.to independently process pancreatic
islet cell for transplantation, a prom-
© 2008 SUNSHINE MEDIA,INC.UNAUTHORIZED USE OFTHIS DOCUMENT IS STRICTLY PROHIBITED.
islet cell for transplantation, a prom-
ising experimental procedure on
© 2008 SUNSHINE MEDIA,INC.UNAUTHORIZED USE OFTHIS DOCUMENT IS STRICTLY PROHIBITED.
ising experimental procedure on
which they are currently conducting
© 2008 SUNSHINE MEDIA,INC.UNAUTHORIZED USE OFTHIS DOCUMENT IS STRICTLY PROHIBITED.
which they are currently conducting
research and clinical trials, and have
© 2008 SUNSHINE MEDIA,INC.UNAUTHORIZED USE OFTHIS DOCUMENT IS STRICTLY PROHIBITED.
research and clinical trials, and have
© 2008 SUNSHINE MEDIA,INC.UNAUTHORIZED USE OFTHIS DOCUMENT IS STRICTLY PROHIBITED.
7. FORT WORTH/DALLAS M.D. NEWS NOVEMBER 2008 | 5
at Baylor All Saints Medical Center at
Fort Worth and Medical Director of
the Islet Cell Transplant Program.
While much work needs to be done,
the procedure is already showing as-
tounding results and has researchers
hopeful in the possibility of eliminat-
ing the need for insulin injections for
most patients with type 1 diabetes.
DRAWING WORLD-
RENOWNED
RESEARCHERS
This major research program is
having an impact not only locally and
nationally, but also internationally
as well, drawing top researchers to
the state-of-the-art facilities. “The
addition of the world-renowned islet cell researcher
Shinichi Matsumoto, M.D., Ph.D., of Kyoto, Japan, not
only strengthens us, but is also an incredible validation
of our preparatory work up to this point,” says Dr. Levy.
“Dr. Matsumoto’s standing as a world-class investigator
in pancreatic islet cell transplantation propels Baylor All
Saints to the front ranks of this field, and brings to the Fort
Worth medical community exciting research in the area
of juvenile diabetes, transplantation and immunology.”
Dr. Matsumoto is the world’s only islet cell transplant
researcher to have performed an islet cell transplant
from a living donor. He was drawn to the Baylor All
Saints research facilities because of their implementation
of superior techniques and top technology of islet isola-
tion for islet transplantation. “When I was in Japan, we
did not have access to brain-dead donors. Therefore, we
had to isolate islets from nonheartbeating donors. Islet
isolation from a nonheartbeating donor is very difficult.”
He continues, “I performed more than 200 pig islet isola-
tions in order to develop the technology to isolate islets
even from nonheartbeating donors. This large amount
of research made it possible for us to achieve the highest
success rate of islet isolation.” He now serves as Director,
Baylor All Saints Islet Cell Research, and Director,
The addition of the
world-renowned islet
cell researcher Shinichi
Matsumoto, M.D., Ph.D.,
of Kyoto, Japan, not only
strengthens us, but is also
an incredible validation of
our preparatory work up
to this point.
— Marlon Levy, M.D., Surgical
Director of Transplantation at Baylor
All Saints Medical Center and Medical
Director of the Islet Cell Program
“Islet cell transplantation is considered to be a prototype of cell therapy and/or regenerative
medicine. Therefore, a lot of basic sciences are focusing on making islet cells using stem
cells, gene therapy or regenerative medicine,” says Shinichi Matsumoto, M.D., Ph.D.,
Director, All Saints Islet Cell Research, and Director, Baylor Institute for Immunology
Research Islet Cell Transplantation Research.
R
hopeful in the possibility of eliminat-
R
hopeful in the possibility of eliminat-
ing the need for insulin injections for
R
ing the need for insulin injections for
R
most patients with type 1 diabetes.
R
most patients with type 1 diabetes.
DRAWING WORLD-
RDRAWING WORLD-
RENOWNEDRRENOWNED
E
tounding results and has researchers
E
tounding results and has researchers
hopeful in the possibility of eliminat-
E
hopeful in the possibility of eliminat-
ing the need for insulin injections for
E
ing the need for insulin injections for
Emost patients with type 1 diabetes.
Emost patients with type 1 diabetes.
DRAWING WORLD-EDRAWING WORLD-
V
the procedure is already showing as-
V
the procedure is already showing as-
tounding results and has researchers
V
tounding results and has researchers
hopeful in the possibility of eliminat-
V
hopeful in the possibility of eliminat-
ing the need for insulin injections for
Ving the need for insulin injections for
Vmost patients with type 1 diabetes.
Vmost patients with type 1 diabetes.
II
the procedure is already showing as-
I
the procedure is already showing as-
tounding results and has researchers
Itounding results and has researchers
hopeful in the possibility of eliminat-
Ihopeful in the possibility of eliminat-
ing the need for insulin injections for
Iing the need for insulin injections for EEW ONLYYLYL
© 2008 SUNSHINE MEDIA,INC.UNAUTHORIZED USE OFTHIS DOCUMENT IS STRICTLY PROHIBITED.
© 2008 SUNSHINE MEDIA,INC.UNAUTHORIZED USE OFTHIS DOCUMENT IS STRICTLY PROHIBITED.
© 2008 SUNSHINE MEDIA,INC.UNAUTHORIZED USE OFTHIS DOCUMENT IS STRICTLY PROHIBITED.
most patients with type 1 diabetes.
© 2008 SUNSHINE MEDIA,INC.UNAUTHORIZED USE OFTHIS DOCUMENT IS STRICTLY PROHIBITED.
most patients with type 1 diabetes.
DRAWING WORLD-
© 2008 SUNSHINE MEDIA,INC.UNAUTHORIZED USE OFTHIS DOCUMENT IS STRICTLY PROHIBITED.
DRAWING WORLD-
RENOWNED
© 2008 SUNSHINE MEDIA,INC.UNAUTHORIZED USE OFTHIS DOCUMENT IS STRICTLY PROHIBITED.
RENOWNED
RESEARCHERS© 2008 SUNSHINE MEDIA,INC.UNAUTHORIZED USE OFTHIS DOCUMENT IS STRICTLY PROHIBITED.
RESEARCHERS
8. 6 | FORT WORTH/DALLAS M.D. NEWS NOVEMBER 2008
Baylor Institute for Immunology Research Islet Cell
Transplantation Research.
PHYSICIANS OFFERING SUPPORT
The program is also exciting news to area physicians who
want to see their patients receive the benefits of advanced
treatment. Patients in these studies have experienced an
extremely high rate of success, with many patients elimi-
nating the need for insulin or having a significantly reduced
need. “We are enjoying incredibly strong support in the
medical community and are honored every time a patient
is referred to us,” comments Dr. Levy about gratitude
toward local physicians. “Not only does it speak highly
of the level of trust put in our staff, but also the deep
commitment that physicians have for the well-being of
their patients who endure the substantial burden caused
by the disease.” With less than 20 islet research teams
nationwide, Baylor is the only hospital in the Southwest
performing islet cell transplantation and is an important
regional point of access to this groundbreaking treatment
for patients with diabetes.
RESEARCH FRONTS
The research has garnered interest on many major
fronts. “Islet cell transplantation is considered to be a
prototype of cell therapy and/or regenerative medicine.
Therefore, a lot of basic sciences are focusing on making
islet cells using stem cells, gene therapy or regenerative
medicine.” Explains Dr. Matsumoto, “In addition, islet
cell transplantation is considered to be the most promis-
ing treatment for using animal cells. If we were able to
use animal cells in a clinical setting, we would no longer
need to worry about organ donor shortage.” The yearly
increase of patients with diabetes coupled with an insuf-
ficient supply of islet donors is one of the barriers yet to
be overcome in islet cell transplantation. While the use
of xenographs and the generation of
islets from cell culture are possible
sources of an adequate supply of is-
lets and show some promise, there
are still many obstacles to overcome
before it becomes a clinical reality.
“This is why we have enormous grati-
tude for our donor families and their
generosity. This is life-changing research that could not
happen without them.” Dr. Levy reflectively adds, “That
significance is not lost to us.”
PERSONALLY GRATIFYING
Excitement is certainly contagious and the positive
results are fueling continued interest. “One of the most
personally gratifying patients recently was one of our own
transplant family. He has lived 20 years with diabetes and
has made his life’s work finding organs for transplant. His
diabetes was limiting in that his glucose would become
critically low with no clues. After treatment, he has done
very well and has continued to have good glucose control,”
says Dr. Levy. In fact, it is difficult for the staff not to be
enthusiastic when their patients can be among the first to
participate in the trials and receive the benefit of recent
breakthroughs. Dr. Matsumoto finds the possibilities
thrilling. “Ultimately, this program will focus on finding
cures for diabetes, not only type 1, but also type 2. With
improved efficacy and reduced side effects of islet trans-
plantation, we will perform a lot of this treatment to the
diabetic patients. Currently, there are approximately 20
million diabetic patients in the United States. Advanced
research should reduce this number significantly.”
“This work is extremely rewarding. Every challenge
brings new opportunity and fuels a desire to find a cure
that cannot be quenched,” says Dr. Levy. “Our staff has
a tremendous amount of gratitude for the patients who
share in this journey and the trust that they place in us.
Dr. Matusumoto adds, “We should not forget that every
advanced medicine is for patients. Therefore, we do every
research for patients’ satisfaction. Our best efforts should
always be about the patients.”
For more information on islet cell transplantation, please contact
1-800-4Baylor or visit www.BaylorHealth.com. ■
We should not forget that every advanced medicine
is for patients. Therefore, we do every research
for patients’ satisfaction. Our best efforts should always
be about the patients.
— Shinichi Matsumoto, M.D., Ph.D., Director, All Saints Islet
Cell Research, and Director, Baylor Institute for Immunology
Research Islet Cell Transplantation Research
R
of the level of trust put in our staff, but also the deep
R
of the level of trust put in our staff, but also the deep
commitment that physicians have for the well-being of
R
commitment that physicians have for the well-being of
their patients who endure the substantial burden caused
R
their patients who endure the substantial burden caused
by the disease.” With less than 20 islet research teams
Rby the disease.” With less than 20 islet research teams
nationwide, Baylor is the only hospital in the Southwest
Rnationwide, Baylor is the only hospital in the Southwest
performing islet cell transplantation and is an importantRperforming islet cell transplantation and is an important
E
toward local physicians. “Not only does it speak highly
E
toward local physicians. “Not only does it speak highly
of the level of trust put in our staff, but also the deep
E
of the level of trust put in our staff, but also the deep
commitment that physicians have for the well-being of
E
commitment that physicians have for the well-being of
their patients who endure the substantial burden caused
Etheir patients who endure the substantial burden caused
by the disease.” With less than 20 islet research teams
Eby the disease.” With less than 20 islet research teams
nationwide, Baylor is the only hospital in the SouthwestEnationwide, Baylor is the only hospital in the Southwest
V
is referred to us,” comments Dr. Levy about gratitude
V
is referred to us,” comments Dr. Levy about gratitude
toward local physicians. “Not only does it speak highly
V
toward local physicians. “Not only does it speak highly
of the level of trust put in our staff, but also the deep
Vof the level of trust put in our staff, but also the deep
commitment that physicians have for the well-being of
Vcommitment that physicians have for the well-being of
their patients who endure the substantial burden caused
Vtheir patients who endure the substantial burden caused
by the disease.” With less than 20 islet research teamsVby the disease.” With less than 20 islet research teams
I
medical community and are honored every time a patient
I
medical community and are honored every time a patient
is referred to us,” comments Dr. Levy about gratitude
I
is referred to us,” comments Dr. Levy about gratitude
toward local physicians. “Not only does it speak highly
Itoward local physicians. “Not only does it speak highly
of the level of trust put in our staff, but also the deep
Iof the level of trust put in our staff, but also the deep
commitment that physicians have for the well-being of
Icommitment that physicians have for the well-being ofE
need. “We are enjoying incredibly strong support in the
E
need. “We are enjoying incredibly strong support in the
medical community and are honored every time a patient
E
medical community and are honored every time a patient
is referred to us,” comments Dr. Levy about gratitude
Eis referred to us,” comments Dr. Levy about gratitude
toward local physicians. “Not only does it speak highly
Etoward local physicians. “Not only does it speak highly
of the level of trust put in our staff, but also the deep
Eof the level of trust put in our staff, but also the deep
commitment that physicians have for the well-being ofEcommitment that physicians have for the well-being of
W
nating the need for insulin or having a significantly reduced
W
nating the need for insulin or having a significantly reduced
need. “We are enjoying incredibly strong support in the
W
need. “We are enjoying incredibly strong support in the
medical community and are honored every time a patient
Wmedical community and are honored every time a patient
is referred to us,” comments Dr. Levy about gratitude
Wis referred to us,” comments Dr. Levy about gratitude
toward local physicians. “Not only does it speak highly
Wtoward local physicians. “Not only does it speak highly
of the level of trust put in our staff, but also the deep
Wof the level of trust put in our staff, but also the deep
personally gratifying patients recently was one of our own
W
personally gratifying patients recently was one of our own
transplant family. He has lived 20 years with diabetes and
W
transplant family. He has lived 20 years with diabetes and
has made his life’s work finding organs for transplant. His
W
has made his life’s work finding organs for transplant. His
diabetes was limiting in that his glucose would become
Wdiabetes was limiting in that his glucose would become
critically low with no clues. After treatment, he has done
Wcritically low with no clues. After treatment, he has done
very well and has continued to have good glucose control,”
Wvery well and has continued to have good glucose control,”
O
results are fueling continued interest. “One of the most
O
results are fueling continued interest. “One of the most
O
personally gratifying patients recently was one of our own
O
personally gratifying patients recently was one of our own
transplant family. He has lived 20 years with diabetes and
Otransplant family. He has lived 20 years with diabetes and
has made his life’s work finding organs for transplant. His
Ohas made his life’s work finding organs for transplant. His
diabetes was limiting in that his glucose would becomeOdiabetes was limiting in that his glucose would become
N
Excitement is certainly contagious and the positive
N
Excitement is certainly contagious and the positive
results are fueling continued interest. “One of the most
N
results are fueling continued interest. “One of the most
Npersonally gratifying patients recently was one of our own
Npersonally gratifying patients recently was one of our own
transplant family. He has lived 20 years with diabetes and
Ntransplant family. He has lived 20 years with diabetes and
has made his life’s work finding organs for transplant. HisNhas made his life’s work finding organs for transplant. His
L
PERSONALLY GRATIFYING
L
PERSONALLY GRATIFYING
Excitement is certainly contagious and the positive
L
Excitement is certainly contagious and the positive
results are fueling continued interest. “One of the most
Lresults are fueling continued interest. “One of the most
Lpersonally gratifying patients recently was one of our own
Lpersonally gratifying patients recently was one of our own
transplant family. He has lived 20 years with diabetes andLtransplant family. He has lived 20 years with diabetes and
YExcitement is certainly contagious and the positive
YExcitement is certainly contagious and the positive
results are fueling continued interest. “One of the most
Yresults are fueling continued interest. “One of the most
personally gratifying patients recently was one of our ownYpersonally gratifying patients recently was one of our own
LYL
Excitement is certainly contagious and the positive
L
Excitement is certainly contagious and the positive
YExcitement is certainly contagious and the positive
L
Excitement is certainly contagious and the positive
results are fueling continued interest. “One of the most
Lresults are fueling continued interest. “One of the most
Yresults are fueling continued interest. “One of the most
Lresults are fueling continued interest. “One of the most
LYLpersonally gratifying patients recently was one of our own
Lpersonally gratifying patients recently was one of our ownYpersonally gratifying patients recently was one of our own
Lpersonally gratifying patients recently was one of our own
© 2008 SUNSHINE MEDIA,INC.UNAUTHORIZED USE OFTHIS DOCUMENT IS STRICTLY PROHIBITED.personally gratifying patients recently was one of our own
© 2008 SUNSHINE MEDIA,INC.UNAUTHORIZED USE OFTHIS DOCUMENT IS STRICTLY PROHIBITED.personally gratifying patients recently was one of our own
transplant family. He has lived 20 years with diabetes and
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transplant family. He has lived 20 years with diabetes and
has made his life’s work finding organs for transplant. His
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has made his life’s work finding organs for transplant. His
diabetes was limiting in that his glucose would become
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diabetes was limiting in that his glucose would become
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of the level of trust put in our staff, but also the deep
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of the level of trust put in our staff, but also the deep
commitment that physicians have for the well-being of
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commitment that physicians have for the well-being of
their patients who endure the substantial burden caused
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their patients who endure the substantial burden caused
by the disease.” With less than 20 islet research teams
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by the disease.” With less than 20 islet research teams
nationwide, Baylor is the only hospital in the Southwest
© 2008 SUNSHINE MEDIA,INC.UNAUTHORIZED USE OFTHIS DOCUMENT IS STRICTLY PROHIBITED.
nationwide, Baylor is the only hospital in the Southwest
performing islet cell transplantation and is an important
© 2008 SUNSHINE MEDIA,INC.UNAUTHORIZED USE OFTHIS DOCUMENT IS STRICTLY PROHIBITED.
performing islet cell transplantation and is an important
regional point of access to this groundbreaking treatment© 2008 SUNSHINE MEDIA,INC.UNAUTHORIZED USE OFTHIS DOCUMENT IS STRICTLY PROHIBITED.
regional point of access to this groundbreaking treatment
critically low with no clues. After treatment, he has done
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critically low with no clues. After treatment, he has done
very well and has continued to have good glucose control,”
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very well and has continued to have good glucose control,”
says Dr. Levy. In fact, it is difficult for the staff not to be
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says Dr. Levy. In fact, it is difficult for the staff not to be
9. FORT WORTH/DALLAS M.D. NEWS NOVEMBER 2008 | 7
Cliff Diving: Not for the Faint of Heart
adventure
Cliff diving has become a popular sport,
due largely to the increased interest of the
mediaandtheincreasedexposureplatform
diving has received in recent times. It re-
mains, however, an extreme sport.
Professional cliff divers perform their
dives from platforms at a maximum height
of 28 meters. At this height, the body’s
impact into the water is nine times greater
than that from a platform of
10 meters.
You don’t have to be a pro-
fessional diver to enjoy cliff
diving. But be forewarned:
Cliff diving is not for the faint
of heart or feeble of body.
What you do need are cour-
age and an extra measure of
physical control. A will of steel
wouldn’t hurt, either.
Instead of heading straight
for the western cliffs of
Acapulco, where cliff diving
is a major pastime and tour-
ist attraction — and, most
importantly, reserved for the
elite of the cliff diving world
— a little cliff diving practice
is in order.
Here are some tips about
safety and technique for the
budding cliff diver:
Start out lower rather than
higher. Scout a safe location to
dive.Thismeansfindinganarea
thatisfreeofrocksinthewater,
one that is exposed to little or
no winds and one that has no
water current.
Start low. When you first
start your cliff diving career,
choose cliffs that are less than
10 feet high. This may seem
too low at first, but consider
this:Divingfroma10-foot-high
cliff will accelerate your body
to speeds of 17 mph as you hit
the water.
And, of course, thanks to
the laws of physics, this speed
accelerates proportionally
withtheheightyoujumpfrom.
So, for example, jumping
See Page 13
RREVIEW OON
of heart or feeble of body.
N
of heart or feeble of body.
What you do need are cour-
N
What you do need are cour-
age and an extra measure of
N
age and an extra measure of
physical control. A will of steel
Nphysical control. A will of steel
wouldn’t hurt, either.
Nwouldn’t hurt, either.
Instead of heading straight
NInstead of heading straight
for the western cliffs ofNfor the western cliffs ofNL
Cliff diving is not for the faint
L
Cliff diving is not for the faint
of heart or feeble of body.
L
of heart or feeble of body.
What you do need are cour-
L
What you do need are cour-
age and an extra measure of
Lage and an extra measure of
physical control. A will of steel
Lphysical control. A will of steel
wouldn’t hurt, either.
Lwouldn’t hurt, either.Y
diving. But be forewarned:
Y
diving. But be forewarned:
Cliff diving is not for the faint
Y
Cliff diving is not for the faint
of heart or feeble of body.
Y
of heart or feeble of body.
What you do need are cour-
YWhat you do need are cour-
age and an extra measure of
Yage and an extra measure of
physical control. A will of steel
Yphysical control. A will of steel
LYL
Cliff diving is not for the faint
L
Cliff diving is not for the faint
Y
Cliff diving is not for the faint
L
Cliff diving is not for the faint
of heart or feeble of body.
L
of heart or feeble of body.
Y
of heart or feeble of body.
L
of heart or feeble of body.
What you do need are cour-
L
What you do need are cour-
YWhat you do need are cour-
L
What you do need are cour-
age and an extra measure of
Lage and an extra measure of
Yage and an extra measure of
Lage and an extra measure of
physical control. A will of steel
Lphysical control. A will of steel
Yphysical control. A will of steel
Lphysical control. A will of steel
wouldn’t hurt, either.
Lwouldn’t hurt, either.Ywouldn’t hurt, either.
Lwouldn’t hurt, either.
© 2008 SUNSHINE MEDIA,INC.UNAUTHORIZED USE OFTHIS DOCUMENT IS STRICTLY PROHIBITED.physical control. A will of steel
© 2008 SUNSHINE MEDIA,INC.UNAUTHORIZED USE OFTHIS DOCUMENT IS STRICTLY PROHIBITED.physical control. A will of steel
wouldn’t hurt, either.
© 2008 SUNSHINE MEDIA,INC.UNAUTHORIZED USE OFTHIS DOCUMENT IS STRICTLY PROHIBITED.
wouldn’t hurt, either.
© 2008 SUNSHINE MEDIA,INC.UNAUTHORIZED USE OFTHIS DOCUMENT IS STRICTLY PROHIBITED.
Instead of heading straight
© 2008 SUNSHINE MEDIA,INC.UNAUTHORIZED USE OFTHIS DOCUMENT IS STRICTLY PROHIBITED.
Instead of heading straight
for the western cliffs of
© 2008 SUNSHINE MEDIA,INC.UNAUTHORIZED USE OFTHIS DOCUMENT IS STRICTLY PROHIBITED.
for the western cliffs of
Acapulco, where cliff diving
© 2008 SUNSHINE MEDIA,INC.UNAUTHORIZED USE OFTHIS DOCUMENT IS STRICTLY PROHIBITED.
Acapulco, where cliff diving
© 2008 SUNSHINE MEDIA,INC.UNAUTHORIZED USE OFTHIS DOCUMENT IS STRICTLY PROHIBITED.
10. 8 | FORT WORTH/DALLAS M.D. NEWS NOVEMBER 2008
N9NE Steakhouse: Leading Dallas
Down a Fresh Steakhouse PathBy Zoe Dunn
restaurant review
“…Tworoadsdivergedinawood,andI
— I took the one less traveled by, and that
has made all the difference.”
— Robert Frost
While a 1900s poem may not have been
going through the minds of the N9NE
Groupastheymasterfullydesignedandcre-
ated N9NE Steakhouse in Victory Park, I
believeittobetheperfectmetaphor.Before
enteringtherestaurant,manywouldexpect
the typical, dark wood, white tablecloth
ambience, commonly found at my daddy’s
steakhouse; instead, you are fascinated to
find the interior of N9NE to be contem-
porary and chic. For example, in place of
RR
porary and chic. For example, in place of
R
porary and chic. For example, in place of
EE
find the interior of N9NE to be contem-
E
find the interior of N9NE to be contem-
porary and chic. For example, in place of
E
porary and chic. For example, in place of
VV
ambience, commonly found at my daddy’s
V
ambience, commonly found at my daddy’s
steakhouse; instead, you are fascinated to
V
steakhouse; instead, you are fascinated to
find the interior of N9NE to be contem-
V
find the interior of N9NE to be contem-
porary and chic. For example, in place of
Vporary and chic. For example, in place of
II
ambience, commonly found at my daddy’s
I
ambience, commonly found at my daddy’s
steakhouse; instead, you are fascinated to
I
steakhouse; instead, you are fascinated to
find the interior of N9NE to be contem-
Ifind the interior of N9NE to be contem-
porary and chic. For example, in place of
Iporary and chic. For example, in place of
IEEW ONLYYLYL
© 2008 SUNSHINE MEDIA,INC.UNAUTHORIZED USE OFTHIS DOCUMENT IS STRICTLY PROHIBITED.
© 2008 SUNSHINE MEDIA,INC.UNAUTHORIZED USE OFTHIS DOCUMENT IS STRICTLY PROHIBITED.
© 2008 SUNSHINE MEDIA,INC.UNAUTHORIZED USE OFTHIS DOCUMENT IS STRICTLY PROHIBITED.
11. dimlightingandbulkyfurniture,N9NEhas
chosentocomplementtheirsleekaesthetic
with suede booths, large, mirrored mosaic
columns and colorful illumination. It is
precisely this bold decision to steer away
from the conventional concept that makes
N9NE so refreshing and luxurious.
Notonlyistheinnovativestyleevidentin
the restaurant’s décor, but also mimicked
throughouteveryelementofthediningex-
perience.Ifitwereme,Iwouldrecommend
starting off with the “shrooms” appetizer,
consisting of nine mushrooms stuffed with
Alaskankingcrabandservedwithlemon.If
youareinthemoodforasalad,thenIwould
suggest the Garbage Salad, made with
romaine lettuce, shrimp, salami, Maytag
blue cheese, cucumber, tomato, hearts of
palm,artichokes,olivesandtoppedoffwith
a tasty Dijon vinaigrette.
As far as entrées go, I would recommend
the Whole Fish Tempura, which is pieces
of fresh fish lightly fried in tempura batter
and presented whole-fish style. And those
looking for a more traditional steakhouse
main course, N9NE also offers a selection
of prime steaks, including the 8 oz. filet,
whichissuretomatchyourexpectations,as
it did mine. Can’t decide whether to order
seafoodorasteak?The“AllSteaksCanSurf”
option, which adds ½ of a Maine lobster to
yoursteak,willsurelysatisfyyourindecisive
desires. So, put away all of that “red meat,
cholesterol” mumbo jumbo, and take the
leap! You will not be disappointed.
To complement your entrée, I would
recommendthepotatognocchiside,served
with a white truffle cream sauce, as well
as — my personal favorite — the creamed
garlic spinach. To top off the meal, I would
suggest the vanilla vodka and Kahlúa
espresso shot … shaken, not stirred.
Commanderofthekitchen,ChefTommy
Simpson, has been a part of the Dallas din-
ingsceneforalongtime,workingforsome
of the city’s most noteworthy restaurants,
includingTheMansionandHotelZaZa.Itis
clear,afterhavingfinishedamealatN9NE,
that Chef Simpson truly understands the
tastes and preferences of his Dallas diners.
Becausetherestaurantislocatedafewfeet
from the American Airlines Center, N9NE
is the perfect place to grab cocktails before
and after the game. And while you will not
be the only one sporting your Mavericks
jersey on a game day, you never know who
youwillrunintoatN9NE(JessicaSimpson,
Mike Modano, etc.), and so most everyone
dressestoimpress.Rephrased:Iwouldsug-
gest leaving the scrubs at home.
On another note, if you are in need of
a venue for a company holiday party or a
room for a corporate event, the private
diningoptionsatN9NEarequiteextensive.
Theprivatediningroomlookedperfectfor
a more intimate gathering, and the restau-
rant is also large enough to accommodate
a sizeable guest list.
By tweaking the customary to fit a more
contemporary atmosphere, N9NE steak-
househascreatedanewwowfactorthatyou
must experience to comprehend. In other
words,N9NESteakhousehastraveleddown
analternativeroadtosteakhousesuccess…
and that has made all of the difference. ■