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For
gammel
til Intensiv?Camilla Strøm, Læge, Ph.d. @dr_stroem
Charles Eugester, startede bodybuilding @ 85 år
fysiologisk reserve
Modificeret fra Uptodate 2018
80år
80år
80år
80år
Mortalitet 80+
Flaaten, Intensive Care Med; 2015; 41: 1996–8
Becker, Ann Intensive Care 2015
indlæggelsesårsag
Funktionsniveau 65+
Sacanella, Crit Care Med 2011
Livskvalitet 80+
Sacanella, Crit Care Med 2011
Andersen Crit Care Med 2017
median VAS-EQ-5D scores
Tab: 61%
Tab > 20 point: 31%
Defineret klinisk
relevant forskel
sundhedsudgifter
Chin-Yee Crit Care 2017
Non-survivor
EUR 26,260
Evidens
interventioner 80+
80år
80år
”MIN MaveforNeMMelse..”
uskønne
Garrouste-Orgeas, Intensive Care Med 2003; 29:774-81
Garrouste-Orgeas, Intensive Care Med 2013;39-1574-83
OUTCOME
MILD KOGNITIV IMPAIRMENT ≠ UDE AF STAND TIL AT UDTRYKKE ØNSKER!
Okonkwo, Neurology 2008;71:1497-104
ice-cub 1
• 80+
• 15 Akutafdelinger i Frankrig
• 2115 patienter
• 13% blev spurgt om
behandlingspræference
• Faktorer associeret med at blive
spurgt
Demens
OR 0.47 95%CI 0.25-0.83
God funktionsevne
OR 2.10 95%CI 1.39-3.21
Inddraget pårørende
OR 5.46 95%CI 3.8-7.88
Senior læge
OR 0.48 95%CI 0.35-0.66
Boumendil, PLoS ONE 2012
Le Guen Age Ageing 2016
ethica
• 80+
• Tidligere indlagte bosiddende i
eget hjem samt gruppe
bosiddende på
plejehjem/beskyttet bolig
• 115 patienter
• 3 scenarier: NIV, IMV, RRT efter
IMV
• 81% og 71% var selvhjulpne (IADL)
• Frabad beh: NIV 27%/
• IMV 43%/RRT 63%
• Faktorer associeret med at ønske
behandling
Levende ægtefælle
Kvindeligt køn
Høj livskvalitet
Philippart, Int Care Med 2013
!
INTENSIV TRIAGE
Garroutste-Orgeas Crit Care Med 2009
Sprung Crit Care Med 2012
Andersen, Crit Care Med 2017
INTENSIV TRIAGE
• 80+
• Norsk multicentre studie
• 355 patienter
• 70% indlagt på ITA
Andersen, Crit Care Med 2017
INTENSIV TRIAGE
• 80+
• Norsk multicentre studie
• 355 patienter
• 70% indlagt på ITA
Systematisk TRIAGE
Guidet, JAMA 2017
24 hospitaler/Frankrig/cluster-
RCT/3037 kritisk
syge/75+/bevaret
funktionsniveau/god
ernæringsstatus/%aktiv cancer
Indlæggelse på ITA
RR 1.68; 95% CI 1.54-1.82
Mortalitet - hospital
RR 1.18; 95% CI 1.03-1.33
Mortalitet - 6 måneder
RR 1.05; 95% CI 0.96-1.14
Velkendte modeller er ikke
kalibreret til brug for de ekstremt
gamle (75+), performer dårligere
Funktionel status (afhængig/delvist
afhængig/uafhængig) før admission
påvirker performance af APACHE IV.
Særligt gør det sig gældende ved
lavere sygdoms ’severity’ scores
Prognostiske
modeller
APACHE
SOFA
SAPS
Rooij, Crit Care 2005
Krinsley, Crit Care 2017
FRAILTY
FRAILTY
bcguidelines.ca
FRAILTY
FRAILTY
FRAILTY & MORTAlitet 80+
Muscedere, Intensive Care Med 2016
Bagshaw, CMAJ 2014
FRAILTY
For
gammel
til Intensiv?
For gammel til
INTENSIV?
Camilla Strøm, Læge, PhD
#dr_stroem
camilla007@gmail.com

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