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Stem Cell Therapy Market By
Treatments (Allogeneic Stem Cell
Therapy, Autologous Stem Cell
Therapy), Applications (Oncology, Eye
Diseases, Central Nervous System
Diseases, Musculoskeletal Diseases,
Wound & Injuries, Metabolic Disorders,
Cardiovascular Disorders, Immune
System Disorders), End-users
(Hospitals, Ambulatory Surgical
Centers) and Geography – Global
Opportunity Analysis and Industry
Forecast, 2014-2022
SCALAR MARKET RESEARCH INC.
OCTOBER 2016
2
Table of Contents
1 Introduction ..................................................................................................................................11
2 Market Overview ..........................................................................................................................12
2.1 Definitions.............................................................................................................................12
2.2 Research Methodology.........................................................................................................13
2.3 Market Segmentation...........................................................................................................15
2.4 Assumptions..........................................................................................................................16
3 Executive Summary.......................................................................................................................17
4 Market Dynamics..........................................................................................................................23
4.1 Drivers...................................................................................................................................24
4.2 Restraints ..............................................................................................................................26
4.3 Opportunities........................................................................................................................27
4.4 Trends ...................................................................................................................................27
5 Industry Analysis...........................................................................................................................28
5.1 Industry Overview.................................................................................................................28
5.2 Regulatory Analysis...............................................................................................................30
5.2.1 Europe...........................................................................................................................30
5.2.2 U.S. FDA.........................................................................................................................30
5.3 Pipeline Analysis....................................................................................................................31
5.4 Pricing Analysis......................................................................................................................34
6 Stem Cell Therapy Market, by Treatments...................................................................................35
6.1 Market Overview ..................................................................................................................35
6.2 Market Share Segmentation.................................................................................................36
6.3 Revenue Segmentation.........................................................................................................38
6.4 Treatments............................................................................................................................39
6.4.1 Allogeneic Stem Cell Therapy........................................................................................39
6.4.2 Autologous Stem Cell Therapy......................................................................................41
7 Stem Cell Therapy Market, by Applications..................................................................................43
7.1 Market Overview ..................................................................................................................43
7.2 Market Share Segmentation.................................................................................................45
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7.3 Revenue Segmentation.........................................................................................................47
7.4 Applications...........................................................................................................................48
7.4.1 Oncology .......................................................................................................................48
7.4.2 Eye Diseases..................................................................................................................50
7.4.3 Central Nervous System Diseases.................................................................................51
7.4.4 Musculoskeletal Diseases .............................................................................................52
7.4.5 Wound & Injuries..........................................................................................................53
7.4.6 Metabolic Disorders......................................................................................................54
7.4.7 Cardiovascular Disorders ..............................................................................................55
7.4.8 Immune System Disorders............................................................................................56
8 Stem Cell Therapy Market, by End-Users .....................................................................................58
8.1 Market Overview ..................................................................................................................58
8.2 Market Share Segmentation.................................................................................................59
8.3 Revenue Share Segmentation...............................................................................................61
8.4 End-Users..............................................................................................................................62
8.4.1 Hospitals........................................................................................................................62
8.4.2 Ambulatory Surgical Centers ........................................................................................63
9 Stem Cell Therapy Market, By Regions.........................................................................................64
9.1 Market Share Segmentation.................................................................................................65
9.2 Revenue Segmentation.........................................................................................................67
9.3 North America.......................................................................................................................68
9.3.1 By Regions.....................................................................................................................69
9.3.1.1 U.S.............................................................................................................................69
9.3.1.2 Canada ......................................................................................................................69
9.3.2 By Treatments...............................................................................................................70
9.3.3 By Applications..............................................................................................................71
9.3.4 By End-Users .................................................................................................................72
9.4 Europe...................................................................................................................................73
9.4.1 By Regions.....................................................................................................................74
9.4.1.1 Germany....................................................................................................................74
9.4.1.2 U.K.............................................................................................................................74
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9.4.1.3 France........................................................................................................................74
9.4.1.4 Spain..........................................................................................................................74
9.4.1.5 Rest of Europe...........................................................................................................75
9.4.2 By Treatments...............................................................................................................76
9.4.3 By Applications..............................................................................................................77
9.4.4 By End-Users .................................................................................................................78
9.5 Asia-Pacific ............................................................................................................................79
9.5.1 By Regions.....................................................................................................................80
9.5.1.1 China .........................................................................................................................80
9.5.1.2 India...........................................................................................................................80
9.5.1.3 Japan .........................................................................................................................80
9.5.1.4 South Korea...............................................................................................................80
9.5.2 By Treatments...............................................................................................................82
9.5.3 By Applications..............................................................................................................83
9.5.4 By End-Users .................................................................................................................84
9.6 Rest of the World (ROW) ......................................................................................................85
9.6.1 By Regions.....................................................................................................................86
9.6.1.1 Latin America ............................................................................................................86
9.6.1.2 Middle East & Africa..................................................................................................86
9.6.2 By Treatments...............................................................................................................87
9.6.3 By Applications..............................................................................................................88
9.6.4 By End-Users .................................................................................................................89
10 Competitive Landscape.................................................................................................................90
10.1 Key Innovator Companies.....................................................................................................90
11 Key Market Players .......................................................................................................................92
11.1 Vericel Corporation...............................................................................................................92
11.1.1 Overview .......................................................................................................................92
11.1.2 Key Strategies................................................................................................................92
11.1.3 Recent Developments...................................................................................................92
11.2 Stem Cells, Inc.......................................................................................................................93
11.2.1 Overview .......................................................................................................................93
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11.2.2 Key Strategies................................................................................................................93
11.2.3 Recent Developments...................................................................................................93
11.3 Mesoblast Ltd........................................................................................................................94
11.3.1 Overview .......................................................................................................................94
11.3.2 Key Strategies................................................................................................................94
11.3.3 Recent Developments...................................................................................................94
11.4 Gamida Cell...........................................................................................................................95
11.4.1 Overview .......................................................................................................................95
11.4.2 Key Strategies................................................................................................................95
11.4.3 Recent Developments...................................................................................................95
11.5 Osiris Therapeutics, Inc.........................................................................................................96
11.5.1 Overview .......................................................................................................................96
11.5.2 Key Strategies................................................................................................................96
11.5.3 Recent Developments...................................................................................................96
11.6 Chiesi Farmaceutici S.p.A......................................................................................................97
11.6.1 Overview .......................................................................................................................97
11.6.2 Key Strategies................................................................................................................97
11.6.3 Recent Developments...................................................................................................97
11.7 ReNeuron Group, plc ............................................................................................................98
11.7.1 Overview .......................................................................................................................98
11.7.2 Key Strategies................................................................................................................98
11.7.3 Recent Developments...................................................................................................98
12 Scalar 360 Degree Market Perspective.........................................................................................99
13 Appendix .....................................................................................................................................100
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List of Tables
Table 1. Research Methodology.....................................................................................................13
Table 2. Assumptions......................................................................................................................16
Table 3. Global Stem Cell Therapy Market Size (US$ billion), (2016-2022)....................................18
Table 4. Global Stem Cell Therapy Market Summary.....................................................................22
Table 5. Stem Cell Therapy Market in emerging countries ............................................................27
Table 6. Stem Cell Therapeutic Products Available in the Market .................................................28
Table 7. Stem Cell Therapies in Phase 3 & Pre-registration Stage of the Development (2015).....33
Table 8. Companies with Number of Stem Cell Therapies in Pipeline (2015)................................34
Table 9. Average Treatment Costs..................................................................................................34
Table 10. Global Stem Cell Therapy Market Size (US$ billion), By Treatments (2014-2022) ...........38
Table 11. Global Allogeneic Stem Cell Therapy Market Size (US$ billion), By Regions (2014-2022)39
Table 12. Global Autologous Stem Cell Therapy Market Size (US$ billion),By Regions (2014-2022)
41
Table 13. Global Stem Cell Therapy Market Size (US$ billion), By Applications (2014-2022)..........47
Table 14. Focused Areas in Oncology for Stem Cell Therapies.........................................................48
Table 15. Global Stem Cell Therapy Market for Oncology; Market Size (US$ billion) (2014-2022).49
Table 16. Global Stem Cell Therapy Market for Eye Diseases; Market Size (US$ billion) (2014-2022)
50
Table 17. Global Stem Cell Therapy Market for Central Nervous System Diseases; Market Size (US$
billion) (2014-2022)...............................................................................................................................51
Table 18. Global Stem Cell Therapy Market for Musculoskeletal Diseases; Market Size (US$ billion)
(2014-2022)52
Table 19. Global Stem Cell Therapy Market for Wound & Injuries; Market Size (US$ billion) (2014-
2022) 53
Table 20. Global Stem Cell Therapy Market for Metabolic Disorders; Market Size (US$ billion)
(2014-2022)54
Table 21. Global Stem Cell Therapy Market for Cardiovascular Disorders; Market Size (US$ billion)
(2014-2022)55
Table 22. Focused Areas in Immune System Disorders for Stem Cell Therapies .............................56
Table 23. Global Stem Cell Therapy Market for Immune System Disorders; Market Size (US$
billion) (2014-2022)...............................................................................................................................57
Table 24. Global Stem Cell Therapy Market Size (US$ billion), By End-users (2014-2022)..............61
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Table 25. Global Stem Cell Therapy Market for Hospitals; Market Size (US$ billion) (2014-2022) .62
Table 26. Global Stem Cell Therapy Market for Ambulatory Surgical Centers; Market Size (US$
billion) (2014-2022)...............................................................................................................................63
Table 27. Global Stem Cell Therapy Market Size (US$ billion), By Regions (2014-2022) .................67
Table 28. Stem Cell Therapy Market in North America; Market Size (US$ billion) (2014-2022)......68
Table 29. Stem Cell Therapy Market in U.S; Market Size (US$ billion), (2014-2022).......................69
Table 30. Stem Cell Therapy Market in Canada; Market Size (US$ billion), (2014-2022) ................69
Table 31. Stem Cell Therapy Market in North America; Market Size (US$ billion), By Treatment
(2014-2022)..........................................................................................................................................70
Table 32. Stem Cell Therapy Market in North America; Market Size (US$ billion), By Applications
(2014-2022)..........................................................................................................................................71
Table 33. Stem Cell Therapy Market in North America; Market Size (US$ billion), By End-users
(2014-2022)...........................................................................................................................................72
Table 34. Stem Cell Therapy Market in Europe; Market Size (US$ billion).......................................73
Table 35. Stem Cell Therapy Market in Germany; Market Size (US$ billion),(2014-2022) ..............74
Table 36. Stem Cell Therapy Market in U.K; Market Size (US$ billion), (2014-2022).......................74
Table 37. Stem Cell Therapy Market in France; Market Size (US$ billion),(2014-2022) ..................74
Table 38. Stem Cell Therapy Market in Spain; Market Size (US$ billion), (2014-2022)....................74
Table 39. Stem Cell Therapy Market in Rest of Europe; Market Size (US$ billion), (2014-2022).....75
Table 40. Stem Cell Therapy Market in Europe; Market Size (US$ billion), By Treatment (2014-
2022).....................................................................................................................................................76
Table 41. Stem Cell Therapy Market in Europe; Market Size (US$ billion), By Applications (2014-
2022).....................................................................................................................................................77
Table 42. Stem Cell Therapy Market in Europe; Market Size (US$ billion), By End-users (2014-
2022).....................................................................................................................................................78
Table 43. Stem Cell Therapy Market in Asia-Pacific; Market Size (US$ billion)................................79
Table 44. Stem Cell Therapy Market in China; Market Size (US$ billion), (2014-2022) ...................80
Table 45. Stem Cell Therapy Market in India; Market Size (US$ billion), (2014-2022) ....................80
Table 46. Stem Cell Therapy Market in Japan; Market Size (US$ billion), (2014-2022)...................80
Table 47. Stem Cell Therapy Market in South Korea; Market Size (US$ billion), (2014-2022).........80
Table 48. Stem Cell Therapy Market in Rest of Asia-Pacific; Market Size (US$ billion), (2014-2022)
81
Table 49. Stem Cell Therapy Market in Asia-Pacific; Market Size (US$ billion), By Treatment (2014-
2022) 82
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Table 50. Stem Cell Therapy Market in Asia-Pacific; Market Size (US$ billion), By Applications
(2014-2022)83
Table 51. Stem Cell Therapy Market in Asia-Pacific; Market Size (US$ billion), By End-users (2014-
2022) 84
Table 52. Stem Cell Therapy Market in Rest of the World (ROW); Market Size (US$ billion)..........85
Table 53. Stem Cell Therapy Market in Latin America; Market Size (US$ billion), (2014-2022) ......86
Table 54. Stem Cell Therapy Market in Middle East & Africa; Market Size (US$ billion), (2014-2022)
86
Table 55. Stem Cell Therapy Market in Rest of the World (ROW); Market Size (US$ billion), By
Treatment (2014-2022).........................................................................................................................87
Table 56. Stem Cell Therapy Market in Rest of the World (ROW); Market Size (US$ billion), By
Applications (2014-2022)......................................................................................................................88
Table 57. Stem Cell Therapy Market in Rest of the World; Market Size (US$ billion), By End-users
(2014-2022)..........................................................................................................................................89
Table 58. Key Innovator Companies.................................................................................................90
Table 59. Acronyms ........................................................................................................................100
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List of Figures
Figure 1. Research Methodology.....................................................................................................14
Figure 2. Global Stem Cell Therapy Market Share(%), By Regions (2016 & 2022) ..........................19
Figure 3. Global Stem Cell Therapy Market Share(%), By Treatments (2016 & 2022) ....................19
Figure 4. Global Stem Cell Therapy Market Share(%), By Applications (2017 & 2022)...................20
Figure 5. Global Stem Cell Therapy Market Share(%), By End-users (2016 & 2022).......................21
Figure 6. Stem Cell Therapy by Stage of Development (2015) ........................................................31
Figure 1. Stem Cell Therapy by Therapeutic Area (2015) ................................................................32
Figure 2. Global Stem Cell Therapy Market Size (US$ billion), By Treatments (2015) ....................35
Figure 3. Global Stem Cells Therapy Market Share (%), By Treatments (2016 & 2022).................36
Figure 4. Global Stem Cells Therapy Market Size (US$ billion), By Treatments (2014-2022).........38
Figure 5. Global Allogeneic Stem Cell Therapy Market Size (US$ billion), By Regions (2016 & 2022)
39
Figure 6. Global Autologous Stem Cell Therapy Market Size (US$ billion), By Regions (2015 & 2022
41
Figure 7. Market Attractiveness for Major Stem Cell Therapy Applications (2017)........................44
Figure 8. Forecasted Global Stem Cell Therapy Market Share (%), By Applications (2017 & 2022)45
Figure 9. Global Stem Cell Therapy Market Size (US$ billion), By Applications (2017 & 2022).......47
Figure 10. Global Stem Cells Therapy Market for Oncology; Market Size (US$ billion) (2017 &
2022) 49
Figure 11. Global Stem Cells Therapy Market for Eye Diseases; Market Size (US$ billion) (2017 &
2022) 50
Figure 12. Global Stem Cells Therapy Market for Central Nervous System Diseases; Market Size
(US$ billion) (2017 & 2022)...................................................................................................................51
Figure 13. Global Stem Cells Therapy Market for Musculoskeletal Diseases; Market Size (US$
billion) (2017 & 2022) ...........................................................................................................................52
Figure 14. Global Stem Cells Therapy Market for Wound & Injuries; Market Size (US$ billion)
(2017 & 2022) 53
Figure 15. Global Stem Cells Therapy Market for Eye Metabolic Disorders; Market Size (US$
billion) (2017 & 2022) ...........................................................................................................................54
Figure 16. Global Stem Cells Therapy Market for Cardiovascular Disorders; Market Size (US$
billion) (2017 & 2022) ...........................................................................................................................55
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Figure 17. Global Stem Cells Therapy Market for Immune System Disorders; Market Size (US$
billion) (2017 & 2022) ...........................................................................................................................56
Figure 18. Global Stem Cell Therapy Market Size (US$ billion), By End-users (2015) ...................58
Figure 19. Global Stem Cell Therapy Market Share(%), By End-Users (2016 & 2022)..................59
Figure 20. Global Stem Cells Therapy Market Size (US$ billion), By End-users (2014-2022) .......61
Figure 21. Global Stem Cells Therapy Market for Hospitals; Market Size (US$ billion) (2016 &
2022) 62
Figure 22. Global Stem Cells Therapy Market for Ambulatory Surgical Centers; Market Size (US$
billion) (2016 & 2022) ...........................................................................................................................63
Figure 23. Global Stem Cell Therapy Market Share (%), By Major Regions(2015 & 2022)............65
Figure 24. Top 5 Countries, By Market Share (%) (2016)...............................................................66
Figure 25. Stem Cell Therapy Market in North America; Market Size (US$ billion)(2014-2022)...68
Figure 26. Stem Cell Therapy Market in North America; Market Size (US$ billion), By Treatment
(2014-2022) 70
Figure 27. Stem Cell Therapy Market in North America; Market Size (US$ billion), By End-users
(2014- 2022) 72
Figure 28. Stem Cell Therapy Market in Europe; Market Size (US$ billion)(2014-2022)...............73
Figure 29. Stem Cell Therapy Market in Europe; Market Size (US$ billion), By Treatment (2014-
2022) 76
Figure 30. Stem Cell Therapy Market in Europe; Market Size (US$ billion), By End-users (2014-
2022) 78
Figure 31. Stem Cell Therapy Market in Asia-Pacific; Market Size (US$ billion)(2014-2022)........79
Figure 32. Stem Cell Therapy Market in Asia-Pacific; Market Size (US$ billion), By Treatment
(2014-2022) 82
Figure 33. Stem Cell Therapy Market in Asia-Pacific; Market Size (US$ billion), By End-users
(2014-2022) 84
Figure 34. Stem Cell Therapy Market in Rest of the World; Market Size (US$ billion) (2014-2022)
85
Figure 35. Stem Cell Therapy Market in Rest of the World; Market Size (US$ billion), By
Treatment (2014-2022).........................................................................................................................87
Figure 36. Stem Cell Therapy Market in Rest of the World (ROW); Market Size (US$ billion), By
End-users (2014-2022)..........................................................................................................................89
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2 Market Overview
2.1 Definitions
Global stem cell therapy market is defined as the market size and market share
estimation of the various segments of the stem cell therapy market, capturing
ongoing drivers, trends, challenges of the market, industry analysis involving the
regulatory analysis, and studying about the major participants and players in stem
cell therapy market environment.
The 'Global Stem Cell Therapy Market – Market Size and Forecast (2014–2022)'
report includes market size and forecast estimates for the period 2014 to 2022. The
scope of this report is commercially available regenerative stem cell therapy
products, pipeline analysis, and application of stem cell therapies in different
diseases. The report segments the market by treatments, applications, end-users,
and regions. The report has 2014 as the historic year, 2015 as base year and years
2016 to 2022 as forecast years.
This report defines stem cell therapy as–
Stem cell therapy is defined as the introduction of the stem cells into the damaged or
diseased tissue. These stem cells posses the ability to renew themselves and give
rise to other cells, which in turn replaces the damaged organs and tissues in the
body. Stem cell therapy comes under the umbrella of the global regenerative
medicines.
Allogeneic Stem cell therapy treatment type as–
Allogeneic transplant is stem cell transplant treatment in which the stem cell are
received by the donor which can be a relative, a family member, or a third person.
Autologous Stem cell therapy treatment type as–
Allogeneic transplant is stem cell transplant treatment in which the stem cell are
received by the patient from his own blood.
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2.2 Research Methodology
The market study of stem cell therapy market incorporates prolonged two-way
approaches, secondary and primary research to collect the information commercially
and study the market. The data collection part was focused, and related to capturing
the whole market from various perspective. Data collected from multiple sources was
logically linked and analyzed by our analysts.
Secondary Data
Secondary data gathering procedure, with subsequent references such as company
websites, journals, magazines, directories, databases such as Bloomberg, Hoovers,
Factiva, company annual reports, press releases, white papers, and government
publishing sources also have been taken into consideration. Data from these
sources has been used to obtain industry analysis, company profiles, and other key
areas such as market drivers, opportunities, and trends from stem cell therapy
market perspective.
Table 1. Research Methodology
Report Parameter Secondary Source
Market Size, Share, Revenue Company Annual Reports, SEC Filings, Financials,
Press Releases, Directories, Journals.
Industry Analysis Company websites, Market journals, White
papers, Magazines, other Market studies.
Competitive Landscape Company Annual Reports, Financials, Press
Releases, Investors Relations, Directories,
Journals.
Primary Data
Primary data is the most important data in the research study. Primary data has
been considered and linked to the report to make the study more crisp and
informative. Structured interviews with industry specialists, VPs, CEO’s, directors,
technology consultants were taken to collect the key primary data. The primary data
was focused on both, the demand and supply side of the market. Market Engineering
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was carried out from the data, and excessive analysis has been done on it. Primary
data was also considered extensively in validating the secondary content. Market
engineering process involved both top-down and bottom-up approach to estimate the
market size and market forecast and segment the market into more sub-segments.
Market size estimation
Both, top-down and bottom-up approaches were used to estimate the size of the
global stem cell therapy market.
Figure 1. Research Methodology
Global
Market
Size
Market-specific
Revenues of Key Market
Players
Revenues of Key Market Players
Global Market
Size
Segment-specific
Market Size
Regional
Market
Size
Bottom-up
Top-down
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2.3 Market Segmentation
Stem Cell Therapy Market
Treatments Applications End-users Regions
•Allogeneic Stem
Cell Therapy
• Autologous
StemCell
Therapy
•Oncology
•CentralNervous
SystemDiseases
•EyeDiseases
•Musculoskeletal
Diseases
•Wound & Injuries
•Metabolic
Disorders
•Cardiovascular
Disorders
•ImmuneSystem
Disorders
• Hospitals
• Ambulatory
SurgicalCenters
• North America
• Europe
• Asia-Pacific
• Rest of the
World
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3 Executive Summary
Stem cell therapy is defined as the introduction of the stem cells into the damaged or
diseased tissue. These stem cells posses the ability to renew themselves and give
rise to other cells, which in turn replaces the damaged organs and tissues in the
body. Stem cell therapy comes under the umbrella of the global regenerative
medicines.
The stem cell therapy market offers many growth opportunities and driving factors as
compared to the restraining factors. It is stated by various research scientists that
development of stem cell population and their preservation will be essential for
commercialization of stem cell therapies. Thus, large numbers of key companies
such as Baxter International., Teva Pharmaceutical, and others are in constant
efforts to develop stem cell therapies. For which, these companies are rigorously
increasing their research and development expenses on clinical trials to introduce
stem cell therapies which would ultimately drive the market growth. Furthermore,
demand for stem cell therapies is also expected to increase due to the rise in the
incidence of life-threatening diseases such as cancer, cardiovascular disorders, and
others. For these diseases, stem cell therapies have proven a promising option for
the disease diagnosis and mitigation. However, a strict regulatory framework for the
stem cell therapies to develop these products restricts companies to invest in this
market, leading to hampering the market growth during the future period.
The major revenue opportunities are expected to come from application sectors such
as Oncology, Cardiovascular disorders, and immune system disorders. Whereas
cardiovascular disorders will account for 50.4% of the total revenue generated by
2022, oncology and immune system disorders will demand a great potential towards
stem cell therapy market. Allogeneic based stem cell therapy will dominate in the
stem cell therapy market while autologous based stem cell therapy will see the
decrease during the forecast as large number of stem cell therapies for
cardiovascular diseases are already in phase 3 and pre-registration stages. Areas
for investment in the stem cell therapy market will focus on improving research and
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Figure 2. Global Stem Cell Therapy Market Share(%), By Regions (2016 & 2022)
59.1%
25.5%
12.0%
3.5%
57.1%
26.1%
13.2%
3.6%
North America
Europe
Asia-Pacific
Rest of the World
Source: Scalar Market Research Analysis
Figure 3. Global Stem Cell Therapy Market Share(%), By Treatments (2016 & 2022)
48.3%51.7%
37.7%
62.3%
Autologous
Allogeneic
Source: Scalar Market Research Analysis
Inside circle shows the market share for the year 2016 & outside circle shows market share
for the year 2022.
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Table 4. Global Stem Cell Therapy Market Summary
Global Stem Cell Therapy Market
Market Size (US$ billion) CAGR%
(2016-2022)2016 2022
Total 11.99 60.94 31.1
Treatment
Autologous Stem Cell Therapy
Allogeneic Stem Cell Therapy
Applications
Oncology
Eye Diseases
Central Nervous System Diseases
Musculoskeletal Diseases
Wound & Injuries
Metabolic Disorders
Cardiovascular Disorders
Immune System Disorders
End-users
Hospitals
Ambulatory Surgical Centers
Regions
North America
Europe
Asia-Pacific
Rest of the World
Source: Scalar Market Research Analysis
Note: '*’ represents CAGR (2017-2022) as stem cell therapies for these diseases are
still in experimental stages and are expected to enter the market in 2017-2018.
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4 Market Dynamics
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4.1 Drivers
Drivers Impact on the Market
2014-2016 2017-2019 2020-2022
Increase in aging population and
chronic diseases, and their need
of alternative medicines
●=High ◑=Medium ◔=Low
1. Increase in aging population and chronic diseases, and their need of
alternative medicines
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5 Industry Analysis
5.1 Industry Overview
The stem cell industry is still considered as an under-regulated industry. Large
numbers of companies are marketing unproven treatments which can be very
harmful to the patients. There are mostly 15 stem cell therapeutic products available
on the market and has been regulated. All other stem cell procedures are still in
experimental stages.
Hemacord; manufactured by New York Blood Center (NYBC); the cord blood product
was approved by FDA in 2011, is excluded from the list along with four more cord
blood products approved since 2011.
The following table gives the list of stem cell therapeutic products that are
commercially available in the market and regulated. All the following products are
authorized for sales and available in the market and are approved by or regulated by
the federal agency.
Table 6. Stem Cell Therapeutic Products Available in the Market
No. Product Company Country Year of
Release
Indication Regulation
1
2
3
4
5
6
7
8
9
10
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11
12
13
14
15
Source: Scalar Market Research Analysis
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6 Stem Cell Therapy Market, by Treatments
6.1 Market Overview
Figure 2. Global Stem Cell Therapy Market Size (US$ billion), By Treatments
(2015)
USD
9.60
Billion
On the basis of treatments, the global stem cell therapy market is segmented into
allogeneic stem cell therapy and autologous stem cell therapy. Allogeneic stem cell
treatment is expected to be the largest treatment segment of this market in 2016.
This segment was valued at US XX billion and is expected to be valued at US XX
billion in 2016. It is expected to have a XX% share of the total stem cell therapy
market in 2016. It is also expected to be the fastest-growing market segment. This
segment will grow at a CAGR of XX% between 2016 and 2022, to reach USXX
billion by 2022.
Allogeneic Stem Cell Therapy| US XX Billion
Autologous Stem Cell Therapy |US XX Billion
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6.3 Revenue Segmentation
Figure 4. Global Stem Cells Therapy Market Size (US$ billion), By Treatments
(2014-2022)
4.04
4.83
5.78
7.23
9.06
11.38
14.34
18.12
22.96
3.67
4.77
6.20
8.38
11.33
15.31
20.71
28.03
37.98
2014 2015 2016 2017 2018 2019 2020 2021 2022
Autologous Allogeneic
Source: Scalar Market Research Analysis
Table 10. Global Stem Cell Therapy Market Size (US$ billion), By Treatments
(2014-2022)
Treatment 2014 2015 2016 2017 2018 2019 2020 2021 2022 CAGR% (2016-2022)
Autologous
Allogeneic
TOTAL 31.1%
Source: Scalar Market Research Analysis
Allogeneic stem cell therapy treatment accounts for the largest treatment of the stem
cell therapy market in 2015. This market segment is expected to grow at a CAGR of
XX% from USXX billion in 2015 to US XX billion in 2022.
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7 Stem Cell Therapy Market, by Applications
7.1 Market Overview
The applications segment of the Stem Cell Therapy market included in this report are
Oncology diseases, Eye Diseases, Central Nervous System Diseases,
Musculoskeletal Diseases, Wound & Injuries, Metabolic Disorders, Cardiovascular
Diseases, and Immune system disorders. Musculoskeletal diseases, wound &
injuries, and eye diseases were the largest application segments in 2015, but is
expected to lose its market share to cardiovascular diseases and oncology diseases
during the forecast period.
This report gives the market size of stem cell therapy for eye diseases,
musculoskeletal diseases, and wound & injuries application segments for years 2014
to 2016, considering these applications as widely accepted as safe and effectively
proven by the medical community. All other application segments are still in
experimental stages and yet to be proven; thus their market sizes are forecasted
from 2017 to 2022 accordingly.
SAM
PLE
44
Figure 7. Market Attractiveness for Major Stem Cell Therapy Applications (2017)
Applications Market Size Growth Rate Overall Attractiveness
Wound & Injuries
Musculoskeletal
Diseases
Eye Diseases
Cardiovascular
Disorders
Immune System
Disorders
Metabolic disorders
Central Nervous System
Diseases
Oncology
●=Significantly Attractive ◑=Attractive ◔=Less Attractive
SAM
PLE
47
7.3 Revenue Segmentation
Figure 9. Global Stem Cell Therapy Market Size (US$ billion), By Applications
(2017 & 2022)
0.25
2.11
0.31
4.52
6.19
0.47
1.28
0.47
3.17
2.64
2.57
6.92
9.15
2.74
30.72
3.02
Oncology
Eye Diseases
Central Nervous System
Diseases
Musculoskeletal Diseases
Wound & Injuries
Metabololic Disorders
Cardiovascular Disorders
Immune System Disorders
2022
2017
Source: Scalar Market Research Analysis
Table 13. Global Stem Cell Therapy Market Size (US$ billion), By Applications
(2014-2022)
Applications 2014 2015 2016 2017 2018 2019 2020 2021 2022 CAGR%
(2017-2022)
Oncology
Eye Diseases
Central Nervous
System Diseases
Musculoskeletal
Diseases
Wound & Injuries
Metabolic
Disorders
Cardiovascular
Disorders
Immune System
Disorders
Total 31.3%
Source: Scalar Market Research Analysis
SAM
PLE
58
8 Stem Cell Therapy Market, by End-Users
8.1 Market Overview
Figure 18. Global Stem Cell Therapy Market Size (US$ billion), By End-users (2015)
USD
9.60
Billion
On the basis of end-users, the global stem cell therapy market is segmented into
hospitals and ambulatory surgical centers. Hospitals are expected to be the largest
end-user segment of this market in 2016. This segment is expected to be valued at
US XX billion in 2016. It is expected to have a XX% share of the total stem cell
therapy market in 2016. It is also expected to be the fastest-growing market
segment. This segment will grow at a CAGR of XX% between 2016 and 2022, to
reach US$ XX billion by 2022. However, the prevalence of ambulatory surgical
centers is more in regulated markets as compared to non-regulated markets.
Hospitals| US XX Billion
Ambulatory Surgical Centers |US XX Billion
SAM
PLE
61
8.3 Revenue Share Segmentation
Figure 20. Global Stem Cells Therapy Market Size (US$ billion), By End-users
(2014-2022)
4.87
6.10
7.65
10.00
13.12
17.25
22.75
30.08
39.89
2.83
3.50
4.34
5.61
7.27
9.45
12.31
16.07
21.05
2014 2015 2016 2017 2018 2019 2020 2021 2022
Hospitals Ambulatory Surgical Centres
Source: Scalar Market Research Analysis
Table 24. Global Stem Cell Therapy Market Size (US$ billion), By End-users (2014-
2022)
End-Users 2014 2015 2016 2017 2018 2019 2020 2021 2022 CAGR%
(2016-
2022)
Hospitals
Ambulatory
Surgical Centers
TOTAL 31.1%
Source: Scalar Market Research Analysis
SAM
PLE
64
9 Stem Cell Therapy Market, By Regions
The regional segments of the Stem Cell Therapy market included in this report are
North America (NA), Europe (EU), Asia-Pacific (APAC), and the Rest of the World
(ROW). North America was the largest regional segment in 2015, while North
America, and Asia Pacific is expected to be the fastest-growing regional segment in
the forecast period.
SAM
PLE
65
9.1 Market Share Segmentation
Figure 23. Global Stem Cell Therapy Market Share (%), By Major Regions (2015 &
2022)
59.1%
25.5%
12.0%
3.5%
57.1%
26.1%
13.2%
3.6%
North America
Europe
Asia-Pacific
Rest of the World
Source: Scalar Market Research Analysis
Inside circle shows the market share for the year 2016 & outside circle shows market share
for the year 2022.
SAM
PLE
90
10 Competitive Landscape
10.1 Key Innovator Companies
The stem cell therapy industry is highly fragmented, and there are many companies
in the world who are targeting stem cell therapeutic products. In Europe, itself there
are more than 100 companies developing stem cell therapies and there are more
than 400 clinics for stem cell therapy in U.S. alone. The following table gives the list
of key innovators in stem cell therapeutics products across the geography.
Table 58. Key Innovator Companies
Geography/Country Company
United States
Asia-Pacific
Europe
SAM
PLE
91
Israel
Source: Scalar Market Research AnalysisSAM
PLE
100
13 Appendix
Table 59. Acronyms
CAGR Compounded Annual Growth Rate
NA North America
EU Europe
APAC Asia-Pacific
ROW Rest of the World
LA Latin America
NR Not Reported
R&D Research & Development
EMA European Medicines Agency
CNS Central Nervous System
SC Stem Cell
SAM
PLE

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Stem cell therpay market global revenue, trends, growth, share, size and forecast to 2022

  • 1. 1 Stem Cell Therapy Market By Treatments (Allogeneic Stem Cell Therapy, Autologous Stem Cell Therapy), Applications (Oncology, Eye Diseases, Central Nervous System Diseases, Musculoskeletal Diseases, Wound & Injuries, Metabolic Disorders, Cardiovascular Disorders, Immune System Disorders), End-users (Hospitals, Ambulatory Surgical Centers) and Geography – Global Opportunity Analysis and Industry Forecast, 2014-2022 SCALAR MARKET RESEARCH INC. OCTOBER 2016
  • 2. 2 Table of Contents 1 Introduction ..................................................................................................................................11 2 Market Overview ..........................................................................................................................12 2.1 Definitions.............................................................................................................................12 2.2 Research Methodology.........................................................................................................13 2.3 Market Segmentation...........................................................................................................15 2.4 Assumptions..........................................................................................................................16 3 Executive Summary.......................................................................................................................17 4 Market Dynamics..........................................................................................................................23 4.1 Drivers...................................................................................................................................24 4.2 Restraints ..............................................................................................................................26 4.3 Opportunities........................................................................................................................27 4.4 Trends ...................................................................................................................................27 5 Industry Analysis...........................................................................................................................28 5.1 Industry Overview.................................................................................................................28 5.2 Regulatory Analysis...............................................................................................................30 5.2.1 Europe...........................................................................................................................30 5.2.2 U.S. FDA.........................................................................................................................30 5.3 Pipeline Analysis....................................................................................................................31 5.4 Pricing Analysis......................................................................................................................34 6 Stem Cell Therapy Market, by Treatments...................................................................................35 6.1 Market Overview ..................................................................................................................35 6.2 Market Share Segmentation.................................................................................................36 6.3 Revenue Segmentation.........................................................................................................38 6.4 Treatments............................................................................................................................39 6.4.1 Allogeneic Stem Cell Therapy........................................................................................39 6.4.2 Autologous Stem Cell Therapy......................................................................................41 7 Stem Cell Therapy Market, by Applications..................................................................................43 7.1 Market Overview ..................................................................................................................43 7.2 Market Share Segmentation.................................................................................................45 SAM PLE
  • 3. 3 7.3 Revenue Segmentation.........................................................................................................47 7.4 Applications...........................................................................................................................48 7.4.1 Oncology .......................................................................................................................48 7.4.2 Eye Diseases..................................................................................................................50 7.4.3 Central Nervous System Diseases.................................................................................51 7.4.4 Musculoskeletal Diseases .............................................................................................52 7.4.5 Wound & Injuries..........................................................................................................53 7.4.6 Metabolic Disorders......................................................................................................54 7.4.7 Cardiovascular Disorders ..............................................................................................55 7.4.8 Immune System Disorders............................................................................................56 8 Stem Cell Therapy Market, by End-Users .....................................................................................58 8.1 Market Overview ..................................................................................................................58 8.2 Market Share Segmentation.................................................................................................59 8.3 Revenue Share Segmentation...............................................................................................61 8.4 End-Users..............................................................................................................................62 8.4.1 Hospitals........................................................................................................................62 8.4.2 Ambulatory Surgical Centers ........................................................................................63 9 Stem Cell Therapy Market, By Regions.........................................................................................64 9.1 Market Share Segmentation.................................................................................................65 9.2 Revenue Segmentation.........................................................................................................67 9.3 North America.......................................................................................................................68 9.3.1 By Regions.....................................................................................................................69 9.3.1.1 U.S.............................................................................................................................69 9.3.1.2 Canada ......................................................................................................................69 9.3.2 By Treatments...............................................................................................................70 9.3.3 By Applications..............................................................................................................71 9.3.4 By End-Users .................................................................................................................72 9.4 Europe...................................................................................................................................73 9.4.1 By Regions.....................................................................................................................74 9.4.1.1 Germany....................................................................................................................74 9.4.1.2 U.K.............................................................................................................................74 SAM PLE
  • 4. 4 9.4.1.3 France........................................................................................................................74 9.4.1.4 Spain..........................................................................................................................74 9.4.1.5 Rest of Europe...........................................................................................................75 9.4.2 By Treatments...............................................................................................................76 9.4.3 By Applications..............................................................................................................77 9.4.4 By End-Users .................................................................................................................78 9.5 Asia-Pacific ............................................................................................................................79 9.5.1 By Regions.....................................................................................................................80 9.5.1.1 China .........................................................................................................................80 9.5.1.2 India...........................................................................................................................80 9.5.1.3 Japan .........................................................................................................................80 9.5.1.4 South Korea...............................................................................................................80 9.5.2 By Treatments...............................................................................................................82 9.5.3 By Applications..............................................................................................................83 9.5.4 By End-Users .................................................................................................................84 9.6 Rest of the World (ROW) ......................................................................................................85 9.6.1 By Regions.....................................................................................................................86 9.6.1.1 Latin America ............................................................................................................86 9.6.1.2 Middle East & Africa..................................................................................................86 9.6.2 By Treatments...............................................................................................................87 9.6.3 By Applications..............................................................................................................88 9.6.4 By End-Users .................................................................................................................89 10 Competitive Landscape.................................................................................................................90 10.1 Key Innovator Companies.....................................................................................................90 11 Key Market Players .......................................................................................................................92 11.1 Vericel Corporation...............................................................................................................92 11.1.1 Overview .......................................................................................................................92 11.1.2 Key Strategies................................................................................................................92 11.1.3 Recent Developments...................................................................................................92 11.2 Stem Cells, Inc.......................................................................................................................93 11.2.1 Overview .......................................................................................................................93 SAM PLE
  • 5. 5 11.2.2 Key Strategies................................................................................................................93 11.2.3 Recent Developments...................................................................................................93 11.3 Mesoblast Ltd........................................................................................................................94 11.3.1 Overview .......................................................................................................................94 11.3.2 Key Strategies................................................................................................................94 11.3.3 Recent Developments...................................................................................................94 11.4 Gamida Cell...........................................................................................................................95 11.4.1 Overview .......................................................................................................................95 11.4.2 Key Strategies................................................................................................................95 11.4.3 Recent Developments...................................................................................................95 11.5 Osiris Therapeutics, Inc.........................................................................................................96 11.5.1 Overview .......................................................................................................................96 11.5.2 Key Strategies................................................................................................................96 11.5.3 Recent Developments...................................................................................................96 11.6 Chiesi Farmaceutici S.p.A......................................................................................................97 11.6.1 Overview .......................................................................................................................97 11.6.2 Key Strategies................................................................................................................97 11.6.3 Recent Developments...................................................................................................97 11.7 ReNeuron Group, plc ............................................................................................................98 11.7.1 Overview .......................................................................................................................98 11.7.2 Key Strategies................................................................................................................98 11.7.3 Recent Developments...................................................................................................98 12 Scalar 360 Degree Market Perspective.........................................................................................99 13 Appendix .....................................................................................................................................100 SAM PLE
  • 6. 6 List of Tables Table 1. Research Methodology.....................................................................................................13 Table 2. Assumptions......................................................................................................................16 Table 3. Global Stem Cell Therapy Market Size (US$ billion), (2016-2022)....................................18 Table 4. Global Stem Cell Therapy Market Summary.....................................................................22 Table 5. Stem Cell Therapy Market in emerging countries ............................................................27 Table 6. Stem Cell Therapeutic Products Available in the Market .................................................28 Table 7. Stem Cell Therapies in Phase 3 & Pre-registration Stage of the Development (2015).....33 Table 8. Companies with Number of Stem Cell Therapies in Pipeline (2015)................................34 Table 9. Average Treatment Costs..................................................................................................34 Table 10. Global Stem Cell Therapy Market Size (US$ billion), By Treatments (2014-2022) ...........38 Table 11. Global Allogeneic Stem Cell Therapy Market Size (US$ billion), By Regions (2014-2022)39 Table 12. Global Autologous Stem Cell Therapy Market Size (US$ billion),By Regions (2014-2022) 41 Table 13. Global Stem Cell Therapy Market Size (US$ billion), By Applications (2014-2022)..........47 Table 14. Focused Areas in Oncology for Stem Cell Therapies.........................................................48 Table 15. Global Stem Cell Therapy Market for Oncology; Market Size (US$ billion) (2014-2022).49 Table 16. Global Stem Cell Therapy Market for Eye Diseases; Market Size (US$ billion) (2014-2022) 50 Table 17. Global Stem Cell Therapy Market for Central Nervous System Diseases; Market Size (US$ billion) (2014-2022)...............................................................................................................................51 Table 18. Global Stem Cell Therapy Market for Musculoskeletal Diseases; Market Size (US$ billion) (2014-2022)52 Table 19. Global Stem Cell Therapy Market for Wound & Injuries; Market Size (US$ billion) (2014- 2022) 53 Table 20. Global Stem Cell Therapy Market for Metabolic Disorders; Market Size (US$ billion) (2014-2022)54 Table 21. Global Stem Cell Therapy Market for Cardiovascular Disorders; Market Size (US$ billion) (2014-2022)55 Table 22. Focused Areas in Immune System Disorders for Stem Cell Therapies .............................56 Table 23. Global Stem Cell Therapy Market for Immune System Disorders; Market Size (US$ billion) (2014-2022)...............................................................................................................................57 Table 24. Global Stem Cell Therapy Market Size (US$ billion), By End-users (2014-2022)..............61 SAM PLE
  • 7. 7 Table 25. Global Stem Cell Therapy Market for Hospitals; Market Size (US$ billion) (2014-2022) .62 Table 26. Global Stem Cell Therapy Market for Ambulatory Surgical Centers; Market Size (US$ billion) (2014-2022)...............................................................................................................................63 Table 27. Global Stem Cell Therapy Market Size (US$ billion), By Regions (2014-2022) .................67 Table 28. Stem Cell Therapy Market in North America; Market Size (US$ billion) (2014-2022)......68 Table 29. Stem Cell Therapy Market in U.S; Market Size (US$ billion), (2014-2022).......................69 Table 30. Stem Cell Therapy Market in Canada; Market Size (US$ billion), (2014-2022) ................69 Table 31. Stem Cell Therapy Market in North America; Market Size (US$ billion), By Treatment (2014-2022)..........................................................................................................................................70 Table 32. Stem Cell Therapy Market in North America; Market Size (US$ billion), By Applications (2014-2022)..........................................................................................................................................71 Table 33. Stem Cell Therapy Market in North America; Market Size (US$ billion), By End-users (2014-2022)...........................................................................................................................................72 Table 34. Stem Cell Therapy Market in Europe; Market Size (US$ billion).......................................73 Table 35. Stem Cell Therapy Market in Germany; Market Size (US$ billion),(2014-2022) ..............74 Table 36. Stem Cell Therapy Market in U.K; Market Size (US$ billion), (2014-2022).......................74 Table 37. Stem Cell Therapy Market in France; Market Size (US$ billion),(2014-2022) ..................74 Table 38. Stem Cell Therapy Market in Spain; Market Size (US$ billion), (2014-2022)....................74 Table 39. Stem Cell Therapy Market in Rest of Europe; Market Size (US$ billion), (2014-2022).....75 Table 40. Stem Cell Therapy Market in Europe; Market Size (US$ billion), By Treatment (2014- 2022).....................................................................................................................................................76 Table 41. Stem Cell Therapy Market in Europe; Market Size (US$ billion), By Applications (2014- 2022).....................................................................................................................................................77 Table 42. Stem Cell Therapy Market in Europe; Market Size (US$ billion), By End-users (2014- 2022).....................................................................................................................................................78 Table 43. Stem Cell Therapy Market in Asia-Pacific; Market Size (US$ billion)................................79 Table 44. Stem Cell Therapy Market in China; Market Size (US$ billion), (2014-2022) ...................80 Table 45. Stem Cell Therapy Market in India; Market Size (US$ billion), (2014-2022) ....................80 Table 46. Stem Cell Therapy Market in Japan; Market Size (US$ billion), (2014-2022)...................80 Table 47. Stem Cell Therapy Market in South Korea; Market Size (US$ billion), (2014-2022).........80 Table 48. Stem Cell Therapy Market in Rest of Asia-Pacific; Market Size (US$ billion), (2014-2022) 81 Table 49. Stem Cell Therapy Market in Asia-Pacific; Market Size (US$ billion), By Treatment (2014- 2022) 82 SAM PLE
  • 8. 8 Table 50. Stem Cell Therapy Market in Asia-Pacific; Market Size (US$ billion), By Applications (2014-2022)83 Table 51. Stem Cell Therapy Market in Asia-Pacific; Market Size (US$ billion), By End-users (2014- 2022) 84 Table 52. Stem Cell Therapy Market in Rest of the World (ROW); Market Size (US$ billion)..........85 Table 53. Stem Cell Therapy Market in Latin America; Market Size (US$ billion), (2014-2022) ......86 Table 54. Stem Cell Therapy Market in Middle East & Africa; Market Size (US$ billion), (2014-2022) 86 Table 55. Stem Cell Therapy Market in Rest of the World (ROW); Market Size (US$ billion), By Treatment (2014-2022).........................................................................................................................87 Table 56. Stem Cell Therapy Market in Rest of the World (ROW); Market Size (US$ billion), By Applications (2014-2022)......................................................................................................................88 Table 57. Stem Cell Therapy Market in Rest of the World; Market Size (US$ billion), By End-users (2014-2022)..........................................................................................................................................89 Table 58. Key Innovator Companies.................................................................................................90 Table 59. Acronyms ........................................................................................................................100 SAM PLE
  • 9. 9 List of Figures Figure 1. Research Methodology.....................................................................................................14 Figure 2. Global Stem Cell Therapy Market Share(%), By Regions (2016 & 2022) ..........................19 Figure 3. Global Stem Cell Therapy Market Share(%), By Treatments (2016 & 2022) ....................19 Figure 4. Global Stem Cell Therapy Market Share(%), By Applications (2017 & 2022)...................20 Figure 5. Global Stem Cell Therapy Market Share(%), By End-users (2016 & 2022).......................21 Figure 6. Stem Cell Therapy by Stage of Development (2015) ........................................................31 Figure 1. Stem Cell Therapy by Therapeutic Area (2015) ................................................................32 Figure 2. Global Stem Cell Therapy Market Size (US$ billion), By Treatments (2015) ....................35 Figure 3. Global Stem Cells Therapy Market Share (%), By Treatments (2016 & 2022).................36 Figure 4. Global Stem Cells Therapy Market Size (US$ billion), By Treatments (2014-2022).........38 Figure 5. Global Allogeneic Stem Cell Therapy Market Size (US$ billion), By Regions (2016 & 2022) 39 Figure 6. Global Autologous Stem Cell Therapy Market Size (US$ billion), By Regions (2015 & 2022 41 Figure 7. Market Attractiveness for Major Stem Cell Therapy Applications (2017)........................44 Figure 8. Forecasted Global Stem Cell Therapy Market Share (%), By Applications (2017 & 2022)45 Figure 9. Global Stem Cell Therapy Market Size (US$ billion), By Applications (2017 & 2022).......47 Figure 10. Global Stem Cells Therapy Market for Oncology; Market Size (US$ billion) (2017 & 2022) 49 Figure 11. Global Stem Cells Therapy Market for Eye Diseases; Market Size (US$ billion) (2017 & 2022) 50 Figure 12. Global Stem Cells Therapy Market for Central Nervous System Diseases; Market Size (US$ billion) (2017 & 2022)...................................................................................................................51 Figure 13. Global Stem Cells Therapy Market for Musculoskeletal Diseases; Market Size (US$ billion) (2017 & 2022) ...........................................................................................................................52 Figure 14. Global Stem Cells Therapy Market for Wound & Injuries; Market Size (US$ billion) (2017 & 2022) 53 Figure 15. Global Stem Cells Therapy Market for Eye Metabolic Disorders; Market Size (US$ billion) (2017 & 2022) ...........................................................................................................................54 Figure 16. Global Stem Cells Therapy Market for Cardiovascular Disorders; Market Size (US$ billion) (2017 & 2022) ...........................................................................................................................55 SAM PLE
  • 10. 10 Figure 17. Global Stem Cells Therapy Market for Immune System Disorders; Market Size (US$ billion) (2017 & 2022) ...........................................................................................................................56 Figure 18. Global Stem Cell Therapy Market Size (US$ billion), By End-users (2015) ...................58 Figure 19. Global Stem Cell Therapy Market Share(%), By End-Users (2016 & 2022)..................59 Figure 20. Global Stem Cells Therapy Market Size (US$ billion), By End-users (2014-2022) .......61 Figure 21. Global Stem Cells Therapy Market for Hospitals; Market Size (US$ billion) (2016 & 2022) 62 Figure 22. Global Stem Cells Therapy Market for Ambulatory Surgical Centers; Market Size (US$ billion) (2016 & 2022) ...........................................................................................................................63 Figure 23. Global Stem Cell Therapy Market Share (%), By Major Regions(2015 & 2022)............65 Figure 24. Top 5 Countries, By Market Share (%) (2016)...............................................................66 Figure 25. Stem Cell Therapy Market in North America; Market Size (US$ billion)(2014-2022)...68 Figure 26. Stem Cell Therapy Market in North America; Market Size (US$ billion), By Treatment (2014-2022) 70 Figure 27. Stem Cell Therapy Market in North America; Market Size (US$ billion), By End-users (2014- 2022) 72 Figure 28. Stem Cell Therapy Market in Europe; Market Size (US$ billion)(2014-2022)...............73 Figure 29. Stem Cell Therapy Market in Europe; Market Size (US$ billion), By Treatment (2014- 2022) 76 Figure 30. Stem Cell Therapy Market in Europe; Market Size (US$ billion), By End-users (2014- 2022) 78 Figure 31. Stem Cell Therapy Market in Asia-Pacific; Market Size (US$ billion)(2014-2022)........79 Figure 32. Stem Cell Therapy Market in Asia-Pacific; Market Size (US$ billion), By Treatment (2014-2022) 82 Figure 33. Stem Cell Therapy Market in Asia-Pacific; Market Size (US$ billion), By End-users (2014-2022) 84 Figure 34. Stem Cell Therapy Market in Rest of the World; Market Size (US$ billion) (2014-2022) 85 Figure 35. Stem Cell Therapy Market in Rest of the World; Market Size (US$ billion), By Treatment (2014-2022).........................................................................................................................87 Figure 36. Stem Cell Therapy Market in Rest of the World (ROW); Market Size (US$ billion), By End-users (2014-2022)..........................................................................................................................89 SAM PLE
  • 11. 12 2 Market Overview 2.1 Definitions Global stem cell therapy market is defined as the market size and market share estimation of the various segments of the stem cell therapy market, capturing ongoing drivers, trends, challenges of the market, industry analysis involving the regulatory analysis, and studying about the major participants and players in stem cell therapy market environment. The 'Global Stem Cell Therapy Market – Market Size and Forecast (2014–2022)' report includes market size and forecast estimates for the period 2014 to 2022. The scope of this report is commercially available regenerative stem cell therapy products, pipeline analysis, and application of stem cell therapies in different diseases. The report segments the market by treatments, applications, end-users, and regions. The report has 2014 as the historic year, 2015 as base year and years 2016 to 2022 as forecast years. This report defines stem cell therapy as– Stem cell therapy is defined as the introduction of the stem cells into the damaged or diseased tissue. These stem cells posses the ability to renew themselves and give rise to other cells, which in turn replaces the damaged organs and tissues in the body. Stem cell therapy comes under the umbrella of the global regenerative medicines. Allogeneic Stem cell therapy treatment type as– Allogeneic transplant is stem cell transplant treatment in which the stem cell are received by the donor which can be a relative, a family member, or a third person. Autologous Stem cell therapy treatment type as– Allogeneic transplant is stem cell transplant treatment in which the stem cell are received by the patient from his own blood. SAM PLE
  • 12. 13 2.2 Research Methodology The market study of stem cell therapy market incorporates prolonged two-way approaches, secondary and primary research to collect the information commercially and study the market. The data collection part was focused, and related to capturing the whole market from various perspective. Data collected from multiple sources was logically linked and analyzed by our analysts. Secondary Data Secondary data gathering procedure, with subsequent references such as company websites, journals, magazines, directories, databases such as Bloomberg, Hoovers, Factiva, company annual reports, press releases, white papers, and government publishing sources also have been taken into consideration. Data from these sources has been used to obtain industry analysis, company profiles, and other key areas such as market drivers, opportunities, and trends from stem cell therapy market perspective. Table 1. Research Methodology Report Parameter Secondary Source Market Size, Share, Revenue Company Annual Reports, SEC Filings, Financials, Press Releases, Directories, Journals. Industry Analysis Company websites, Market journals, White papers, Magazines, other Market studies. Competitive Landscape Company Annual Reports, Financials, Press Releases, Investors Relations, Directories, Journals. Primary Data Primary data is the most important data in the research study. Primary data has been considered and linked to the report to make the study more crisp and informative. Structured interviews with industry specialists, VPs, CEO’s, directors, technology consultants were taken to collect the key primary data. The primary data was focused on both, the demand and supply side of the market. Market Engineering SAM PLE
  • 13. 14 was carried out from the data, and excessive analysis has been done on it. Primary data was also considered extensively in validating the secondary content. Market engineering process involved both top-down and bottom-up approach to estimate the market size and market forecast and segment the market into more sub-segments. Market size estimation Both, top-down and bottom-up approaches were used to estimate the size of the global stem cell therapy market. Figure 1. Research Methodology Global Market Size Market-specific Revenues of Key Market Players Revenues of Key Market Players Global Market Size Segment-specific Market Size Regional Market Size Bottom-up Top-down SAM PLE
  • 14. 15 2.3 Market Segmentation Stem Cell Therapy Market Treatments Applications End-users Regions •Allogeneic Stem Cell Therapy • Autologous StemCell Therapy •Oncology •CentralNervous SystemDiseases •EyeDiseases •Musculoskeletal Diseases •Wound & Injuries •Metabolic Disorders •Cardiovascular Disorders •ImmuneSystem Disorders • Hospitals • Ambulatory SurgicalCenters • North America • Europe • Asia-Pacific • Rest of the World SAM PLE
  • 15. 17 3 Executive Summary Stem cell therapy is defined as the introduction of the stem cells into the damaged or diseased tissue. These stem cells posses the ability to renew themselves and give rise to other cells, which in turn replaces the damaged organs and tissues in the body. Stem cell therapy comes under the umbrella of the global regenerative medicines. The stem cell therapy market offers many growth opportunities and driving factors as compared to the restraining factors. It is stated by various research scientists that development of stem cell population and their preservation will be essential for commercialization of stem cell therapies. Thus, large numbers of key companies such as Baxter International., Teva Pharmaceutical, and others are in constant efforts to develop stem cell therapies. For which, these companies are rigorously increasing their research and development expenses on clinical trials to introduce stem cell therapies which would ultimately drive the market growth. Furthermore, demand for stem cell therapies is also expected to increase due to the rise in the incidence of life-threatening diseases such as cancer, cardiovascular disorders, and others. For these diseases, stem cell therapies have proven a promising option for the disease diagnosis and mitigation. However, a strict regulatory framework for the stem cell therapies to develop these products restricts companies to invest in this market, leading to hampering the market growth during the future period. The major revenue opportunities are expected to come from application sectors such as Oncology, Cardiovascular disorders, and immune system disorders. Whereas cardiovascular disorders will account for 50.4% of the total revenue generated by 2022, oncology and immune system disorders will demand a great potential towards stem cell therapy market. Allogeneic based stem cell therapy will dominate in the stem cell therapy market while autologous based stem cell therapy will see the decrease during the forecast as large number of stem cell therapies for cardiovascular diseases are already in phase 3 and pre-registration stages. Areas for investment in the stem cell therapy market will focus on improving research and SAM PLE
  • 16. 19 Figure 2. Global Stem Cell Therapy Market Share(%), By Regions (2016 & 2022) 59.1% 25.5% 12.0% 3.5% 57.1% 26.1% 13.2% 3.6% North America Europe Asia-Pacific Rest of the World Source: Scalar Market Research Analysis Figure 3. Global Stem Cell Therapy Market Share(%), By Treatments (2016 & 2022) 48.3%51.7% 37.7% 62.3% Autologous Allogeneic Source: Scalar Market Research Analysis Inside circle shows the market share for the year 2016 & outside circle shows market share for the year 2022. SAM PLE
  • 17. 22 Table 4. Global Stem Cell Therapy Market Summary Global Stem Cell Therapy Market Market Size (US$ billion) CAGR% (2016-2022)2016 2022 Total 11.99 60.94 31.1 Treatment Autologous Stem Cell Therapy Allogeneic Stem Cell Therapy Applications Oncology Eye Diseases Central Nervous System Diseases Musculoskeletal Diseases Wound & Injuries Metabolic Disorders Cardiovascular Disorders Immune System Disorders End-users Hospitals Ambulatory Surgical Centers Regions North America Europe Asia-Pacific Rest of the World Source: Scalar Market Research Analysis Note: '*’ represents CAGR (2017-2022) as stem cell therapies for these diseases are still in experimental stages and are expected to enter the market in 2017-2018. SAM PLE
  • 19. 24 4.1 Drivers Drivers Impact on the Market 2014-2016 2017-2019 2020-2022 Increase in aging population and chronic diseases, and their need of alternative medicines ●=High ◑=Medium ◔=Low 1. Increase in aging population and chronic diseases, and their need of alternative medicines SAM PLE
  • 20. 28 5 Industry Analysis 5.1 Industry Overview The stem cell industry is still considered as an under-regulated industry. Large numbers of companies are marketing unproven treatments which can be very harmful to the patients. There are mostly 15 stem cell therapeutic products available on the market and has been regulated. All other stem cell procedures are still in experimental stages. Hemacord; manufactured by New York Blood Center (NYBC); the cord blood product was approved by FDA in 2011, is excluded from the list along with four more cord blood products approved since 2011. The following table gives the list of stem cell therapeutic products that are commercially available in the market and regulated. All the following products are authorized for sales and available in the market and are approved by or regulated by the federal agency. Table 6. Stem Cell Therapeutic Products Available in the Market No. Product Company Country Year of Release Indication Regulation 1 2 3 4 5 6 7 8 9 10 SAM PLE
  • 21. 29 11 12 13 14 15 Source: Scalar Market Research Analysis SAM PLE
  • 22. 35 6 Stem Cell Therapy Market, by Treatments 6.1 Market Overview Figure 2. Global Stem Cell Therapy Market Size (US$ billion), By Treatments (2015) USD 9.60 Billion On the basis of treatments, the global stem cell therapy market is segmented into allogeneic stem cell therapy and autologous stem cell therapy. Allogeneic stem cell treatment is expected to be the largest treatment segment of this market in 2016. This segment was valued at US XX billion and is expected to be valued at US XX billion in 2016. It is expected to have a XX% share of the total stem cell therapy market in 2016. It is also expected to be the fastest-growing market segment. This segment will grow at a CAGR of XX% between 2016 and 2022, to reach USXX billion by 2022. Allogeneic Stem Cell Therapy| US XX Billion Autologous Stem Cell Therapy |US XX Billion SAM PLE
  • 23. 38 6.3 Revenue Segmentation Figure 4. Global Stem Cells Therapy Market Size (US$ billion), By Treatments (2014-2022) 4.04 4.83 5.78 7.23 9.06 11.38 14.34 18.12 22.96 3.67 4.77 6.20 8.38 11.33 15.31 20.71 28.03 37.98 2014 2015 2016 2017 2018 2019 2020 2021 2022 Autologous Allogeneic Source: Scalar Market Research Analysis Table 10. Global Stem Cell Therapy Market Size (US$ billion), By Treatments (2014-2022) Treatment 2014 2015 2016 2017 2018 2019 2020 2021 2022 CAGR% (2016-2022) Autologous Allogeneic TOTAL 31.1% Source: Scalar Market Research Analysis Allogeneic stem cell therapy treatment accounts for the largest treatment of the stem cell therapy market in 2015. This market segment is expected to grow at a CAGR of XX% from USXX billion in 2015 to US XX billion in 2022. SAM PLE
  • 24. 43 7 Stem Cell Therapy Market, by Applications 7.1 Market Overview The applications segment of the Stem Cell Therapy market included in this report are Oncology diseases, Eye Diseases, Central Nervous System Diseases, Musculoskeletal Diseases, Wound & Injuries, Metabolic Disorders, Cardiovascular Diseases, and Immune system disorders. Musculoskeletal diseases, wound & injuries, and eye diseases were the largest application segments in 2015, but is expected to lose its market share to cardiovascular diseases and oncology diseases during the forecast period. This report gives the market size of stem cell therapy for eye diseases, musculoskeletal diseases, and wound & injuries application segments for years 2014 to 2016, considering these applications as widely accepted as safe and effectively proven by the medical community. All other application segments are still in experimental stages and yet to be proven; thus their market sizes are forecasted from 2017 to 2022 accordingly. SAM PLE
  • 25. 44 Figure 7. Market Attractiveness for Major Stem Cell Therapy Applications (2017) Applications Market Size Growth Rate Overall Attractiveness Wound & Injuries Musculoskeletal Diseases Eye Diseases Cardiovascular Disorders Immune System Disorders Metabolic disorders Central Nervous System Diseases Oncology ●=Significantly Attractive ◑=Attractive ◔=Less Attractive SAM PLE
  • 26. 47 7.3 Revenue Segmentation Figure 9. Global Stem Cell Therapy Market Size (US$ billion), By Applications (2017 & 2022) 0.25 2.11 0.31 4.52 6.19 0.47 1.28 0.47 3.17 2.64 2.57 6.92 9.15 2.74 30.72 3.02 Oncology Eye Diseases Central Nervous System Diseases Musculoskeletal Diseases Wound & Injuries Metabololic Disorders Cardiovascular Disorders Immune System Disorders 2022 2017 Source: Scalar Market Research Analysis Table 13. Global Stem Cell Therapy Market Size (US$ billion), By Applications (2014-2022) Applications 2014 2015 2016 2017 2018 2019 2020 2021 2022 CAGR% (2017-2022) Oncology Eye Diseases Central Nervous System Diseases Musculoskeletal Diseases Wound & Injuries Metabolic Disorders Cardiovascular Disorders Immune System Disorders Total 31.3% Source: Scalar Market Research Analysis SAM PLE
  • 27. 58 8 Stem Cell Therapy Market, by End-Users 8.1 Market Overview Figure 18. Global Stem Cell Therapy Market Size (US$ billion), By End-users (2015) USD 9.60 Billion On the basis of end-users, the global stem cell therapy market is segmented into hospitals and ambulatory surgical centers. Hospitals are expected to be the largest end-user segment of this market in 2016. This segment is expected to be valued at US XX billion in 2016. It is expected to have a XX% share of the total stem cell therapy market in 2016. It is also expected to be the fastest-growing market segment. This segment will grow at a CAGR of XX% between 2016 and 2022, to reach US$ XX billion by 2022. However, the prevalence of ambulatory surgical centers is more in regulated markets as compared to non-regulated markets. Hospitals| US XX Billion Ambulatory Surgical Centers |US XX Billion SAM PLE
  • 28. 61 8.3 Revenue Share Segmentation Figure 20. Global Stem Cells Therapy Market Size (US$ billion), By End-users (2014-2022) 4.87 6.10 7.65 10.00 13.12 17.25 22.75 30.08 39.89 2.83 3.50 4.34 5.61 7.27 9.45 12.31 16.07 21.05 2014 2015 2016 2017 2018 2019 2020 2021 2022 Hospitals Ambulatory Surgical Centres Source: Scalar Market Research Analysis Table 24. Global Stem Cell Therapy Market Size (US$ billion), By End-users (2014- 2022) End-Users 2014 2015 2016 2017 2018 2019 2020 2021 2022 CAGR% (2016- 2022) Hospitals Ambulatory Surgical Centers TOTAL 31.1% Source: Scalar Market Research Analysis SAM PLE
  • 29. 64 9 Stem Cell Therapy Market, By Regions The regional segments of the Stem Cell Therapy market included in this report are North America (NA), Europe (EU), Asia-Pacific (APAC), and the Rest of the World (ROW). North America was the largest regional segment in 2015, while North America, and Asia Pacific is expected to be the fastest-growing regional segment in the forecast period. SAM PLE
  • 30. 65 9.1 Market Share Segmentation Figure 23. Global Stem Cell Therapy Market Share (%), By Major Regions (2015 & 2022) 59.1% 25.5% 12.0% 3.5% 57.1% 26.1% 13.2% 3.6% North America Europe Asia-Pacific Rest of the World Source: Scalar Market Research Analysis Inside circle shows the market share for the year 2016 & outside circle shows market share for the year 2022. SAM PLE
  • 31. 90 10 Competitive Landscape 10.1 Key Innovator Companies The stem cell therapy industry is highly fragmented, and there are many companies in the world who are targeting stem cell therapeutic products. In Europe, itself there are more than 100 companies developing stem cell therapies and there are more than 400 clinics for stem cell therapy in U.S. alone. The following table gives the list of key innovators in stem cell therapeutics products across the geography. Table 58. Key Innovator Companies Geography/Country Company United States Asia-Pacific Europe SAM PLE
  • 32. 91 Israel Source: Scalar Market Research AnalysisSAM PLE
  • 33. 100 13 Appendix Table 59. Acronyms CAGR Compounded Annual Growth Rate NA North America EU Europe APAC Asia-Pacific ROW Rest of the World LA Latin America NR Not Reported R&D Research & Development EMA European Medicines Agency CNS Central Nervous System SC Stem Cell SAM PLE