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A Vision for Personalized Medicine: Collaboration, Enablement, Technology
- 1. Personalized Medicine Vision built from Collaboration, Enablement, Technology Systems Biology Computational Biology & Chemistry Molecular Libraries Translational Research Clinical / Preclinical Research Diagnostics and Biobanks R &D Architecture Health Informatics Public / Private Partnerships Inter- Disciplinary Research Predictive Preventive Personalized Participatory Molecular Libraries • Biomarkers • Sequence • Structure • Pathways • Imaging • Chemistry Computational Biology & Chemistry • Similarity Search • Semantic Search • Structure and Function Analysis • Molecular Network Interactions • Visual Information Discovery • Virtual Screening Clinical /Preclinical Research • Adaptive Trials • Pharmacokinetics / Pharmacodynamics • Pharmacogenomics • Modeling Simulation Public Private Partnerships • Academic Research Centers • Genomic Testing Laboratories • Nanomedicine, Gene Chips • Biotech and Pharma Firms • Consulting Firms • Regulatory Agencies • Healthcare Providers, Clinics • Payers, Reimbursement Agencies • Federal Agencies - NIH, NCI Interdisciplinary Research • Academic Bioscientists • Molecular Biologists • Bioinformaticians • Cell Biologists • Chemists • Physicians Translational Research • TGEN on Demand • Early PoC in Man • Phase I safety and efficacy • Discovery- Early Development Bridging • Diagnostics for Targeted Treatment Health Informatics • Medical Imaging • Decision Support • Safety Surveillance • Disease Surveillance • Therapy Management • Personalized Health Records • Clinical Research Optimization • Health Outcomes, Econometrics Systems Biology • Integration and Mechanistic Models R&D Architecture • Flexible, scalable • Platform as service • Ease of use, Familiar, Convenient • Service Oriented Architecture Gene Sequence Analysis Comparative Genomics Functional Genomics Structural Genomics SNP Analysis Cheminformatics ADME/T Proteomics Medical Imaging Diagnostics Clinical Trials Virtual Drug Discovery P P P P Diagnostics, Biobanks • Theranostics Collaboration for Partnership, Stewardship, Outreach Enablement of the Pathways to Discovery Technology with Architecture, Infrastructure, Intelligence