This thesis submitted by Sameh Mohamed Naguib Ahmed to Zagazig University's Faculty of Medicine examines single-incision laparoscopic cholecystectomy with intraoperative cholangiography. The thesis is submitted under the supervision of Prof. Tarek Ezzat Abdellatif, Prof. Emad Mohammed Salah, and Dr. Wael Mahmoud Awad to fulfill the requirements for a Master's degree in General Surgery from Zagazig University's Faculty of Medicine.