24. Monday, November 19, 2018 24
-70mv
-59mv
(excitatory postsynaptic potential - EPSP)
Na
Na
Na
Na
Na
2. Summation
Na
Na
does not exceed 15 milliseconds
38. • It is the ability of the synapse (between two neurons) to change in
strength in response to either use or disuse of transmission over
synaptic pathway
39. • It is the ability of the synapse (between two neurons) to change in
strength in response to either use or disuse of transmission over
synaptic pathway
• i.e. synaptic conduction can be strengthen or weakened on the basis
of past experience.
40. • These changes are of great interest because they represent forms of
learning and memory.
43. Post tetanic facilitation
- Definition: This is production of enhanced (increased) PSPs in response to rapid successive stimulation of
the presynaptic neuron.
44. Post tetanic facilitation
- Mechanism: Successive stimulation → Ca++ accumulation in the presynaptic neuron → the elevated Ca++ level
causes more & more vesicles to release their transmitter → producing a greater (enhanced) response of the
postsynaptic neuron.
