Cancer and life style

Life style and cellular changes
What is the story?
Dr. S. Mohammadpour

Lifestyle modification involves altering long-term habits, typically of eating or physical activity,
and maintaining the new behavior for months or years. Lifestyle modification can be used to treat
a range of diseases,
The term lifestyle can denote the interests, opinions, behaviors, and behavioral
orientations of an individual, group, or culture and may include views on politics,
religion, health, intimacy, and more
A lifestyle typically reflects an individual's attitudes, way of life, values, or world view.
lifestyle definition
S.Mohammadpour Sep 2018

Most of the stories have three parts:
Villain
Hero
battle

Diseases are bad guys: like cancers

The role of genes and environment in the development of cancer

Emotions
The mind sends signals, the brain releases chemicals, and these messages are sent to our
cells.
someone that is in love, they are producing huge amounts of the feel-good hormones,
dopamine and oxytocin. These hormones alter our brain chemistry to fulfill the growth potential
of cells.
Fear, releases a different set of chemicals (mainly stress hormones and inflammatory
agents), which signals the cells to stop growing.
nocebo effect= negative thought
placebo effect= positive thoughts

Grandma’s behaviors Leave a Mark on Your Genes
Your ancestors' lousy childhoods or excellent adventures might change your personality, bequeathing anxiety
or resilience by altering the epigenetic expressions of genes in the brain.
•Positive beliefs
•Yoga
•Spirituality
•Prayers
•Positive Images and visualizations
•Electromagnetic shifts
•Optimism
•Intention
•Energy Medicine
•Energy Psychology
•Positive Thinking
•Nurturing
•Gratitude
•Happy Social Networks
•Acts of Kindness
•Meditation
•CompassionS.Mohammadpour Sep 2018

how nurture shapes nature, where nature refers to biological heredity and nurture refers to virtually
everything that occurs during the life-span

Characteristics common to many cancers:

Epigenetic changes:

Epigenetic changes: how the genome learns from experience
you can hack your environment to change your gene expression by epigenetic changes
Epigenetics doesn’t change the genetic code, it changes how that’s read.

Telomeres ‐ non‐coding repeat sequences of DNA; cap and protect chromosomes
– Telomeres shorten with cell division and DNA damage
– Critically short telomeres can lead to
• Cellular senescence
• Genomic instability
– Implications for disease risk
Lifestyle and Environmental Factors Associated with Telomere Length

Your body is made up of 50 trillion cells. Every second your body produces 25 million new cells.
This cell represents any cell of the body a brain cell, skin cell, liver cell etc.
All cells need to be in close proximity to normal circulation or blood flow so they can continue to function properly.
Happy Cells vs. Unhappy Cells
“The Happy Cell”

“The Unhappy Cell”
When food is digested the
nutrients are first processed by
the liver and are then released
into the circulation or blood
stream to feed the cells of our
bodies.
When circulation is
blocked or partially
blocked the required
nutrients can not reach
the cell. We call that cell
“The Unhappy Cell”

 Unhappy cells in our brain are called: headaches, anxiety,
depression, memory loss, alzheimer's or stroke
 Unhappy cells in our chest are called: chest pain, palpitations,
arrhythmia, congestive heart failure, angina, heart attack
 We can do this with any cell in our body and come back with a
cause of poor circulation – even with cancer!

So the heroes??

The battle !!!!!

Carcinogens activate and chemopreventive agents suppress NF-κB activation, a major mediator of
inflammation

The other side of coin …

Various cancers that have been linked to environmental carcinogens. The carcinogens linked
to each cancer is shown inside bracket

Cancers that have been linked to alcohol and smoking. Percentages represent the cancer
mortality attributable to alcohol and smoking in men and women

Cancer deaths (%) linked to diet

Various cancers that have been linked to obesity. In the USA overweight and obesity could
account for 14% of all deaths from cancer in men and 20% of those in women

Now we know Health and Lifestyle Choices Can
Change our Genetic Make-Up

So let’s
BE KIND TO OUR GENES

Cancer and life style

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