The Technology of Self-Tracking: From the Microbiome to Continuous Glucose Monitoring
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Overview of my self-experiments in microbiome diagnostics, continuous glucose monitoring and more. Presentation for Me Convention, Frankfurt Germany, Sept 12, 2019
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The Technology of Self-Tracking: From the Microbiome to Continuous Glucose Monitoring
- 1. The Technology of Self-Tracking From the Microbiome to Continuous Glucose Monitoring @sprague Richard Sprague
- 2. Microbiome
- 3. #science
- 7. http://betabeat.com/2014/04/seth-roberts-final-column-butter-makes-me- smarter/ Learning from Brain Reaction Time Worse Better
- 8. BrainReaction Time test is remarkablystable
- 9. Worse Better
- 15. 0 - 6 6 - 7 7 - 8 8 - 9 0 - 2 16 62 84 34 2 - 6 0 1 0 2 6 - 10 0 9 5 2 10 - 15 1 4 3 4 Z (hrs) mg Welch Two Sample t-test t = -1.1048, df = 34.861, p-value = 0.2768 95 percent confidence interval: -0.85 … 0.25 sample estimates mean of x: 6.93 mean of y: 7.23 N = 32 (CBD) N = 172 (no CBD) No Effect on Sleep
- 16. Microbes are everywhere The vast majority of the DNA in and on your body comes from microbes, most of them co- evolved with humans and much older than we are.
- 17. You can test your microbiome
- 20. Blue line represents days on which I drank kombucha (3+ bottles/day) GT’s drinksadd the patented Bacillus coagulans GBI-30,6086, Kombuchadoesn’t domuch
- 22. Microbiome and Diet Tily, et al. Gut microbiome activity contributes to individual variation in glycemic response in adults Zeevi, D., Korem, T., Zmora, N., Israeli, D., Rothschild, D., Weinberger, A., … Segal, E. (2015). Personalized Nutrition by Prediction of Glycemic Responses. Cell, 163(5), 1079–1094. https://doi.org/10.1016/j.cell.2015.11.001
- 24. That’s not a needle. It’s a filament sprague@personalscience.com
- 30. Sleep
Editor's Notes
- We live in a Golden Age for personal science: New, lost-cost technology makes it much easier for all of us to be scientists.
- The first meaning – I think the most common one – is a sense of wonder about the world.
- Another meaning – very common as well – associates science with technology. “Cool stuff people have been able to do”
- Here are the results from his classic self-experiment. He found that he had better results on this test on days after he had eaten half a stick of butter. He was pretty sure of the results, having tested it many times over many years. He even got a bunch of you (working with Genomera) to crowdsource a bigger test.
- Imagine my surprise when, analyzing the data later, I found this. red lines are with fish oil; blue lines without [higher is better]
- Here’s the most popular wearable. Maybe you use it to track your activity – and there are many interesting things you can learn if you just use the built-in apps. But what else is there?
- http://darwinian-medicine.com/wp-content/uploads/2015/01/human_ecosystem.jpg https://68.media.tumblr.com/243136221766e8fd6c6d357ff0ce0fe8/tumblr_o0fx6nYXph1qio57co1_1280.jpg Also see: https://www.differencebetween.com/wp-content/uploads/2017/06/Difference-Between-Microbiome-and-Microbiota-1.jpg
- I’m a little bit crazy…I’ve tested myself quite a bit. Since 2014 I’ve been testing my microbiome a lot – almost daily.
- https://www.biorxiv.org/content/10.1101/641019v2
- https://www.nissinfoods.com/products/top-ramen-noodles