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The Value of
Innovation in Canada
Carole Watson, Director, Strategic Pricing, Janssen Inc.
Canadian Expert Patients in Health Technology Conference
Canadian Organization for Rare Disorders
November 7-8, Toronto.
Chris Halyk
President, Janssen Inc.
Canadian Expert Patients in Health Technology Conference
Canadian Organization for Rare Disorders
November 7-8, Toronto.
Artwork by Sebastian Ferreira
Janssen is proud to feature artwork created by people affected
by the illnesses and diseases we are committed to treating and preventing.
Dr. Paul Janssen
“There are still many diseases
for which there is no cure, and
effective medicines must be
found.
Although we have contributed to
the solutions for some of these
problems, we will continue our
research efforts, because so
much more needs to be done.”
Canadian Expert Patients in Health Technology Conference
Canadian Organization for Rare Disorders
November 7-8, Toronto.
16-11-09
Some Believe…
“Our healthcare system is not
sustainable because of the
cost of drugs.”
4
Canadian Expert Patients in Health Technology Conference
Canadian Organization for Rare Disorders
November 7-8, Toronto.
16-11-09
Medicines are responsible for the
increased costs of healthcare
Myth:
Canadian Expert Patients in Health Technology Conference
Canadian Organization for Rare Disorders
November 7-8, Toronto.
16-11-09
Innovative medicines make up just over 6% of
healthcare spending in Canada
Source: Canadian Health Policy Institute, Spending on Patented Drugs in Canada 1990-2014, February 23, 2016
Canadian Expert Patients in Health Technology Conference
Canadian Organization for Rare Disorders
November 7-8, Toronto.
16-11-09
In 15 years drug costs grew 0.5%, while all other
healthcare spending grew 13%
$0
$500
$1,000
$1,500
$2,000
$2,500
$3,000
Health Spending per capita
in Canada (Public & Private)
Hospitals, Institutions,
Capital
Physicians, Professionals
Public Health,
Administration, Health
Research, Other
Patented Drugs
Source: Canadian Health Policy Institute, Spending on Patented Drugs in Canada , 1990-2014, February 23, 2016;
7
Canadian Expert Patients in Health Technology Conference
Canadian Organization for Rare Disorders
November 7-8, Toronto.
16-11-09
8
Pharmaceutical companies are
free to charge whatever they want
Myth:
Canadian Expert Patients in Health Technology Conference
Canadian Organization for Rare Disorders
November 7-8, Toronto.
16-11-09
Canada has robust systems for assessing price
and reimbursement
Health Canada
Patented Medicine Prices
Review Board
HTA (CDR, INESSS,
pCODR)
Pan Canadian Pharmaceutical
Alliance (pCPA)
Private Insurer
Assessments
Provincial Payer Listings
(PLAs)
“Drugwatch” type
programs
Price and value
hurdles between
innovation and
patients in Canada
Canadian Expert Patients in Health Technology Conference
Canadian Organization for Rare Disorders
November 7-8, Toronto.
16-11-09
§  Patients are always at the center
§  Broad understanding of value –
to patients, healthcare system, society
§  Access for patients today
§  Incentive for investment in
biomedical innovation to transform the
lives of patients tomorrow
Medicines are priced to ensure patient access
today – and tomorrow
Canadian Expert Patients in Health Technology Conference
Canadian Organization for Rare Disorders
November 7-8, Toronto.
16-11-09
Developing innovative medicines is a long,
expensive, and risky process
Source: DiMasi et al 2016. Innovation in the pharmaceutical industry:
New estimates of R&D costs. J Health Econ. 47: 20-33.
Canadian Expert Patients in Health Technology Conference
Canadian Organization for Rare Disorders
November 7-8, Toronto.
16-11-09
Innovative medicines are simply
a cost to the healthcare system
and do not provide substantial
value
Myth:
Canadian Expert Patients in Health Technology Conference
Canadian Organization for Rare Disorders
November 7-8, Toronto.
16-11-09
Medicines help Canadians have longer,
healthier, more productive lives
73% of the
improvement in life
expectancy is estimated
to be due to medicines
over this decade
2 of 3 people diagnosed
with cancer today survive
5 years, compared to 1 in 3
in 1964
A 20-year-old diagnosed
with HIV today can expect
to live into his or her 70’s
Life expectancy: Lichtenberg, F. R., 2014. Health Policy and Technology 3, pp. 36-58. Cancer: National Cancer Institute website. Available at:
http://seer.cancer.gov/csr/1975_2012/browse_csr.php HIV: Samji, H. et al., 2012. PLOS ONE, 8(12), p. e81355.
13
Canadian Expert Patients in Health Technology Conference
Canadian Organization for Rare Disorders
November 7-8, Toronto.
16-11-09
Hepatitis C is curable
Medicines help Canadians have longer, healthier,
more productive lives and decrease healthcare
spending
Sources: PhRMA, 2014. http://www.phrma.org/sites/default/files/pdf/Hep-C-Report-2014-Stepping-Stones.pdf
Lichtenberg FR. Benefits and costs of newer drugs: An Update. National Bureau of Economic Research (NBER), Working Paper no. 8996, 2002.
http://www.myelomabeacon.com/news/2013/11/01/multiple-myeloma-survival-significantly-increases-last-decade/
http://www.myelomacanada.ca/docs/recent%20increase%20in%20survival%20110207.pdf
For every $1 spent on
innovative medicines, non-
medicine spending drops by $7
14
Canadian Expert Patients in Health Technology Conference
Canadian Organization for Rare Disorders
November 7-8, Toronto.
Patients treated for the
blood cancer Multiple
Myeloma have shown a 32%
increase in Survival – from
2000 to 2010.
16-11-09
Threats to the Value of Medicines within our
Healthcare System
Cost-Containment Focus
Ignoring the Value of Innovative Medicines
Therapeutic Substitution
Non-Medical Switching
Restricted Patient and HCP Choice
15
leading to…
Canadian Expert Patients in Health Technology Conference
Canadian Organization for Rare Disorders
November 7-8, Toronto.
16-11-09
Focus on cost-containment
16
Canadian Expert Patients in Health Technology Conference
Canadian Organization for Rare Disorders
November 7-8, Toronto.
PMPRB	
  reform	
  |	
  pCPA	
  |	
  Na1onal	
  Pharmacare	
  |Private	
  payers	
  |	
  SEB	
  first	
  principles	
  
	
  
How to balance today’s budgets with
support for future innovation?
16-11-09
Federal Innovation Agenda
•  Federal Ministry of Innovation, Science and Economic Development (ISED)
has defined a new vision to build Canada as a centre of global innovation
•  $800 million in funding starting in 2017-18
•  Three areas vital to Canadian innovation:
1.  Clean tech
2.  Life Sciences
3.  IT
Life Sciences Question:
Are provincial Ministries of
Health aligned with ensuring
timely access and health system
adoption of innovative
technologies to improve health
outcomes for Canadians?
Canadian Expert Patients in Health Technology Conference
Canadian Organization for Rare Disorders
November 7-8, Toronto.
16-11-09
So What Do We Need To Do?
u  Focus on our shared priorities
u  Ensure short-term decisions do not have long-
term negative impacts
u  Collaboration is key – a partnership for better
patient outcomes and healthcare sustainability
u  We encourage everyone to be informed on the
value of innovation and make your voices heard
18
Canadian Expert Patients in Health Technology Conference
Canadian Organization for Rare Disorders
November 7-8, Toronto.
16-11-09
The Value of Medicines
in Canada
Carole Watson, Director, Strategic Pricing, Janssen Inc.
Canadian Expert Patients in Health Technology Conference
Canadian Organization for Rare Disorders
November 7-8, Toronto.

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Value of Innovation: Carole Watson, Janssen

  • 1. The Value of Innovation in Canada Carole Watson, Director, Strategic Pricing, Janssen Inc. Canadian Expert Patients in Health Technology Conference Canadian Organization for Rare Disorders November 7-8, Toronto.
  • 2. Chris Halyk President, Janssen Inc. Canadian Expert Patients in Health Technology Conference Canadian Organization for Rare Disorders November 7-8, Toronto. Artwork by Sebastian Ferreira Janssen is proud to feature artwork created by people affected by the illnesses and diseases we are committed to treating and preventing.
  • 3. Dr. Paul Janssen “There are still many diseases for which there is no cure, and effective medicines must be found. Although we have contributed to the solutions for some of these problems, we will continue our research efforts, because so much more needs to be done.” Canadian Expert Patients in Health Technology Conference Canadian Organization for Rare Disorders November 7-8, Toronto. 16-11-09
  • 4. Some Believe… “Our healthcare system is not sustainable because of the cost of drugs.” 4 Canadian Expert Patients in Health Technology Conference Canadian Organization for Rare Disorders November 7-8, Toronto. 16-11-09
  • 5. Medicines are responsible for the increased costs of healthcare Myth: Canadian Expert Patients in Health Technology Conference Canadian Organization for Rare Disorders November 7-8, Toronto. 16-11-09
  • 6. Innovative medicines make up just over 6% of healthcare spending in Canada Source: Canadian Health Policy Institute, Spending on Patented Drugs in Canada 1990-2014, February 23, 2016 Canadian Expert Patients in Health Technology Conference Canadian Organization for Rare Disorders November 7-8, Toronto. 16-11-09
  • 7. In 15 years drug costs grew 0.5%, while all other healthcare spending grew 13% $0 $500 $1,000 $1,500 $2,000 $2,500 $3,000 Health Spending per capita in Canada (Public & Private) Hospitals, Institutions, Capital Physicians, Professionals Public Health, Administration, Health Research, Other Patented Drugs Source: Canadian Health Policy Institute, Spending on Patented Drugs in Canada , 1990-2014, February 23, 2016; 7 Canadian Expert Patients in Health Technology Conference Canadian Organization for Rare Disorders November 7-8, Toronto. 16-11-09
  • 8. 8 Pharmaceutical companies are free to charge whatever they want Myth: Canadian Expert Patients in Health Technology Conference Canadian Organization for Rare Disorders November 7-8, Toronto. 16-11-09
  • 9. Canada has robust systems for assessing price and reimbursement Health Canada Patented Medicine Prices Review Board HTA (CDR, INESSS, pCODR) Pan Canadian Pharmaceutical Alliance (pCPA) Private Insurer Assessments Provincial Payer Listings (PLAs) “Drugwatch” type programs Price and value hurdles between innovation and patients in Canada Canadian Expert Patients in Health Technology Conference Canadian Organization for Rare Disorders November 7-8, Toronto. 16-11-09
  • 10. §  Patients are always at the center §  Broad understanding of value – to patients, healthcare system, society §  Access for patients today §  Incentive for investment in biomedical innovation to transform the lives of patients tomorrow Medicines are priced to ensure patient access today – and tomorrow Canadian Expert Patients in Health Technology Conference Canadian Organization for Rare Disorders November 7-8, Toronto. 16-11-09
  • 11. Developing innovative medicines is a long, expensive, and risky process Source: DiMasi et al 2016. Innovation in the pharmaceutical industry: New estimates of R&D costs. J Health Econ. 47: 20-33. Canadian Expert Patients in Health Technology Conference Canadian Organization for Rare Disorders November 7-8, Toronto. 16-11-09
  • 12. Innovative medicines are simply a cost to the healthcare system and do not provide substantial value Myth: Canadian Expert Patients in Health Technology Conference Canadian Organization for Rare Disorders November 7-8, Toronto. 16-11-09
  • 13. Medicines help Canadians have longer, healthier, more productive lives 73% of the improvement in life expectancy is estimated to be due to medicines over this decade 2 of 3 people diagnosed with cancer today survive 5 years, compared to 1 in 3 in 1964 A 20-year-old diagnosed with HIV today can expect to live into his or her 70’s Life expectancy: Lichtenberg, F. R., 2014. Health Policy and Technology 3, pp. 36-58. Cancer: National Cancer Institute website. Available at: http://seer.cancer.gov/csr/1975_2012/browse_csr.php HIV: Samji, H. et al., 2012. PLOS ONE, 8(12), p. e81355. 13 Canadian Expert Patients in Health Technology Conference Canadian Organization for Rare Disorders November 7-8, Toronto. 16-11-09
  • 14. Hepatitis C is curable Medicines help Canadians have longer, healthier, more productive lives and decrease healthcare spending Sources: PhRMA, 2014. http://www.phrma.org/sites/default/files/pdf/Hep-C-Report-2014-Stepping-Stones.pdf Lichtenberg FR. Benefits and costs of newer drugs: An Update. National Bureau of Economic Research (NBER), Working Paper no. 8996, 2002. http://www.myelomabeacon.com/news/2013/11/01/multiple-myeloma-survival-significantly-increases-last-decade/ http://www.myelomacanada.ca/docs/recent%20increase%20in%20survival%20110207.pdf For every $1 spent on innovative medicines, non- medicine spending drops by $7 14 Canadian Expert Patients in Health Technology Conference Canadian Organization for Rare Disorders November 7-8, Toronto. Patients treated for the blood cancer Multiple Myeloma have shown a 32% increase in Survival – from 2000 to 2010. 16-11-09
  • 15. Threats to the Value of Medicines within our Healthcare System Cost-Containment Focus Ignoring the Value of Innovative Medicines Therapeutic Substitution Non-Medical Switching Restricted Patient and HCP Choice 15 leading to… Canadian Expert Patients in Health Technology Conference Canadian Organization for Rare Disorders November 7-8, Toronto. 16-11-09
  • 16. Focus on cost-containment 16 Canadian Expert Patients in Health Technology Conference Canadian Organization for Rare Disorders November 7-8, Toronto. PMPRB  reform  |  pCPA  |  Na1onal  Pharmacare  |Private  payers  |  SEB  first  principles     How to balance today’s budgets with support for future innovation? 16-11-09
  • 17. Federal Innovation Agenda •  Federal Ministry of Innovation, Science and Economic Development (ISED) has defined a new vision to build Canada as a centre of global innovation •  $800 million in funding starting in 2017-18 •  Three areas vital to Canadian innovation: 1.  Clean tech 2.  Life Sciences 3.  IT Life Sciences Question: Are provincial Ministries of Health aligned with ensuring timely access and health system adoption of innovative technologies to improve health outcomes for Canadians? Canadian Expert Patients in Health Technology Conference Canadian Organization for Rare Disorders November 7-8, Toronto. 16-11-09
  • 18. So What Do We Need To Do? u  Focus on our shared priorities u  Ensure short-term decisions do not have long- term negative impacts u  Collaboration is key – a partnership for better patient outcomes and healthcare sustainability u  We encourage everyone to be informed on the value of innovation and make your voices heard 18 Canadian Expert Patients in Health Technology Conference Canadian Organization for Rare Disorders November 7-8, Toronto. 16-11-09
  • 19. The Value of Medicines in Canada Carole Watson, Director, Strategic Pricing, Janssen Inc. Canadian Expert Patients in Health Technology Conference Canadian Organization for Rare Disorders November 7-8, Toronto.