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Quick Start Guide

         2012. 4




  http://www.mongkie.org


                           1/20
CONTENTS

 CONTENTS
  • Overview
  • Features
  • Installation
  • Tutorials
  • Development




                   2/20
Overview

 MONGKIE
   •   MONGKIE is an integrated network visualization platform which allows us to analyze inter-
       connected biological data in an interactive manner with knowledge integration environment. It
       provides Import/Export Network, Expression Overlay, Network Clustering/Grouping, Pathway
       Integration/Visualization, Over-Representing Analysis(GO/Pathway) and Analysis Pipelines
       consisting of other modules.




                                                                                                   3/20
Features (1/5)

 Features
   • Integration & Analysis
        Import/ Export Gene List & Network

        Network Exploring

        Network Clustering & Ranking

        Expression Overlay

        Over-representation Analysis(GO, Pathway)

        Pathway DB Integration Analysis OR Individual Analysis

        Network Pipeline Analysis consisting of integration and analysis
         modules(Commonly used network analysis)


                                                                            4/20
Features (2/5)

 Features
   • Visualization
       Supports various types of nodes, edges and arrows (To represent
        diverse types of biological entities, interactions and controls)

       Offers automatic graph layouts and graph manipulation techniques

       Customize visual properties through the integrated visual editor UI

       Explore networks in many ways through Expansion, Zooming, Panning,
        Highlighting, Dragging, Grouping, Filtering, search Functionalities

       Export as XML, CSV, EPS, SVG and various bitmap images




                                                                              5/20
Features (3/5)

 Features
   • Optimized Data
       Integrated Protein-Protein interaction data

       Integrated Pathway data (from KoPath, Integrated Human Pathway
        Database)

       Can be easily applied to any biological data which can be modeled as
        network structures (ex) gene-drug-disease interaction and association
        network)




                                                                           6/20
Features (4/5)

 Features
   • Architecture (1/2)
        Java-based application built on top of NetBeans platform that supports
         modular(plug-in) architecture

        Platform-independent & easily extendable with additional functionalities




                                                                             7/20
Features (5/5)

 Features
   • Architecture (2/2)




                          8/20
Installation

 Requirements
   • Java SE Download
        http://www.oracle.com/technetwork/java/javase/downloads/index.html

   • Download Mongkie :
        http://mongkie.org/index.php/download

 Installation
   • Windows
        mongkie-x.x-alpha-windows.exe file to run. Then, installer wizard runs

   • Linux
        #sh mongkie-x.x-alpha-linux.sh



                                                                              9/20
Tutorials

 case 1.
   • Import GraphML File
   • Network Exploring and Layout Setting
   • Clustering & Grouping
   • Export to Image




                                            10/20
Tutorials

 Create Network
   • Import file




                   11/20
Tutorials

 Create Network
   • Import file




                   12/20
Tutorials

 Create Network
   • Import file




                   13/20
Tutorials

 Create Network
   • Imported Network




                        14/20
Tutorials

 Network Exploring
   • find UBC (symbol name)




                              15/20
Tutorials

 Setting Layout




                   16/20
Tutorials

 Clutering & Grouping
   • Select Clustering Algorithm and run

            Select algorithm


                                    Run




                               Select Group




                                              17/20
Tutorials

 Export
   • Export to Image(JPEG)




                             18/20
 Export
  • Export to Image




                      19/20
Q&A

http://www.mongkie.org




                         20/20

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201204quickstartguide

  • 1. Quick Start Guide 2012. 4 http://www.mongkie.org 1/20
  • 2. CONTENTS  CONTENTS • Overview • Features • Installation • Tutorials • Development 2/20
  • 3. Overview  MONGKIE • MONGKIE is an integrated network visualization platform which allows us to analyze inter- connected biological data in an interactive manner with knowledge integration environment. It provides Import/Export Network, Expression Overlay, Network Clustering/Grouping, Pathway Integration/Visualization, Over-Representing Analysis(GO/Pathway) and Analysis Pipelines consisting of other modules. 3/20
  • 4. Features (1/5)  Features • Integration & Analysis  Import/ Export Gene List & Network  Network Exploring  Network Clustering & Ranking  Expression Overlay  Over-representation Analysis(GO, Pathway)  Pathway DB Integration Analysis OR Individual Analysis  Network Pipeline Analysis consisting of integration and analysis modules(Commonly used network analysis) 4/20
  • 5. Features (2/5)  Features • Visualization  Supports various types of nodes, edges and arrows (To represent diverse types of biological entities, interactions and controls)  Offers automatic graph layouts and graph manipulation techniques  Customize visual properties through the integrated visual editor UI  Explore networks in many ways through Expansion, Zooming, Panning, Highlighting, Dragging, Grouping, Filtering, search Functionalities  Export as XML, CSV, EPS, SVG and various bitmap images 5/20
  • 6. Features (3/5)  Features • Optimized Data  Integrated Protein-Protein interaction data  Integrated Pathway data (from KoPath, Integrated Human Pathway Database)  Can be easily applied to any biological data which can be modeled as network structures (ex) gene-drug-disease interaction and association network) 6/20
  • 7. Features (4/5)  Features • Architecture (1/2)  Java-based application built on top of NetBeans platform that supports modular(plug-in) architecture  Platform-independent & easily extendable with additional functionalities 7/20
  • 8. Features (5/5)  Features • Architecture (2/2) 8/20
  • 9. Installation  Requirements • Java SE Download  http://www.oracle.com/technetwork/java/javase/downloads/index.html • Download Mongkie :  http://mongkie.org/index.php/download  Installation • Windows  mongkie-x.x-alpha-windows.exe file to run. Then, installer wizard runs • Linux  #sh mongkie-x.x-alpha-linux.sh 9/20
  • 10. Tutorials  case 1. • Import GraphML File • Network Exploring and Layout Setting • Clustering & Grouping • Export to Image 10/20
  • 11. Tutorials  Create Network • Import file 11/20
  • 12. Tutorials  Create Network • Import file 12/20
  • 13. Tutorials  Create Network • Import file 13/20
  • 14. Tutorials  Create Network • Imported Network 14/20
  • 15. Tutorials  Network Exploring • find UBC (symbol name) 15/20
  • 17. Tutorials  Clutering & Grouping • Select Clustering Algorithm and run Select algorithm Run Select Group 17/20
  • 18. Tutorials  Export • Export to Image(JPEG) 18/20
  • 19.  Export • Export to Image 19/20