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Hypoglycemia
HYPOGLYCEMIA
Characterized by an abnormally low level of blood sugar
below a set point
Normal range : 70-110 mg/dL or 3.9-6.1mmol/L
 Glucose is body’s main energy source
 Hypoglycemia is Not a disease in itself
 But the Indicator of health problems
SYMPTOMS:
The main symptoms
associated with
hypoglycemia are:
Mild symptoms
•Sweating
•Fatigue
•Heart palpitation
•dizziness
•Shakiness
•weakness
•Anxiety
•irritability
•Hunger
•Pale skin
•Tingling sensation
Severe Symptoms
when hypoglycemia is more severe then following signs and
symptoms are possible
Abnormal behavior
Confusion
Convulsions
Loss of consciousness (uncommon)
Blurred vision
Clumsiness
seizures ( uncommon)
And in extreme cases, coma
Demographics
• Occur most common in people
with type 1 or type 2 diabetes
• Occur in men ,women ,children,
the elderly
• Not race specific
• Genetically dependent
Blood Sugar
Regulation Breakdown of
carbohydrates
Various Sugar
molecules
One of these
molecules is
glucose
Glucose
absorbed into
blood stream
But it can’t enter
most of the cells
without the help
of insulin
ISLET OF
LANGERHANS
( group of pancreatic
cells ) directly respond
to level of blood
glucose.
Contain BETA-cell
These are associated
with INSULIN
production.
Contain ALFA-cell
They secrete
GLUCAGON.
Level of glucose
rises
Signals to beta
cells to release
insulin
Insulin unlocks the
cells
Provide fuel,
glucose to cells
Extra glucose
stored in liver and
muscles
in form of glycogen
This process lowers
the glucose level in
blood stream
Prevent it from
reaching dangerously
high levels.
HIGH
• Increased
Glucose Level
Level of glucose
decrease
Signals to alpha
cells to secrete
glucagon
Signals to the liver
break down the
stored glycogen
Release glucose
back to blood
stream
Keep sugar level
in normal range
• Aside from breaking
of glycogen into
glucose by liver, body
has ability to
manufacture glucose
in a process called
Gluconeogenesis
• primarily occur in
liver but also in
kidneys
Low
• Decreased
Glucose Level
TYPES OF HYPOGLYCEMIA
DIABETIC HYPOGLYCEMIA
Related to low blood glucose level occurring in a person
with diabetes mellitus.
One of the most common types of hypoglycemia seen in emergency
departments and hospitals.
NON-DIABETIC HYPOGLYCEMIA
Related to some disease, They have further two categories.
 REACTIVE HYPOGLYCEMIA
 NON-REACTIVE HYPOGLYCEMIA
These are also known as causes of Hypoglycemia.
CAUSES OF HYPOGLYCEMIA:
Reactive hypoglycemia:(Postprandial hypoglycemia)
 Reactive hypoglycemia occurs within a few hours after a
meal.
 Occur in people having sugary stomach
Causes:
An over-production of insulin
an indication for developing diabetes.
NON-REACTIVE HYPOGLYCEMIA:(Fasting
hypoglycemia)
Isn't necessarily related to meal, may be due to an underlying
disease.
Causes:
Some medications, like those used in adults and children
with kidney failure
excess amounts of alcohol
any disorder that affects the liver, heart, or kidneys
Anorexia nervosa
Rare tumor of pancreas (insulinoma)
hormonal deficiency
Prevention
• Checking blood glucose levels - keep a regular check
on blood sugar levels and identify the onset of
symptoms.
• Eat regularly - keep to your eating routine.
• Alcohol - a heavy drinking session can trigger
hypoglycemia so prevent alcohol consumption
• Exercise - make sure you have eaten some carbo
 NOTE
Recognize the signs and symptoms of hypoglycemia
early because untreated hypoglycemia can lead to:
• Seizure
• Loss of consciousness
• Deathhydrate-rich food before you do any exercise
Unawareness of hypoglycemia
Overtime repeated episodes of hypoglycemia can lead to
unawareness of hypoglycemia
Body and brain no longer produce signs and symptoms that warn
of low blood sugar level such as
shakiness
Irregular heart beats
when this happen risk of life threaten hypoglycemia is increased.

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Hypoglycemia

  • 1.
  • 3. HYPOGLYCEMIA Characterized by an abnormally low level of blood sugar below a set point Normal range : 70-110 mg/dL or 3.9-6.1mmol/L  Glucose is body’s main energy source  Hypoglycemia is Not a disease in itself  But the Indicator of health problems
  • 4. SYMPTOMS: The main symptoms associated with hypoglycemia are: Mild symptoms •Sweating •Fatigue •Heart palpitation •dizziness •Shakiness •weakness •Anxiety •irritability •Hunger •Pale skin •Tingling sensation
  • 5. Severe Symptoms when hypoglycemia is more severe then following signs and symptoms are possible Abnormal behavior Confusion Convulsions Loss of consciousness (uncommon) Blurred vision Clumsiness seizures ( uncommon) And in extreme cases, coma
  • 6. Demographics • Occur most common in people with type 1 or type 2 diabetes • Occur in men ,women ,children, the elderly • Not race specific • Genetically dependent
  • 7. Blood Sugar Regulation Breakdown of carbohydrates Various Sugar molecules One of these molecules is glucose Glucose absorbed into blood stream But it can’t enter most of the cells without the help of insulin ISLET OF LANGERHANS ( group of pancreatic cells ) directly respond to level of blood glucose. Contain BETA-cell These are associated with INSULIN production. Contain ALFA-cell They secrete GLUCAGON.
  • 8. Level of glucose rises Signals to beta cells to release insulin Insulin unlocks the cells Provide fuel, glucose to cells Extra glucose stored in liver and muscles in form of glycogen This process lowers the glucose level in blood stream Prevent it from reaching dangerously high levels. HIGH • Increased Glucose Level
  • 9. Level of glucose decrease Signals to alpha cells to secrete glucagon Signals to the liver break down the stored glycogen Release glucose back to blood stream Keep sugar level in normal range • Aside from breaking of glycogen into glucose by liver, body has ability to manufacture glucose in a process called Gluconeogenesis • primarily occur in liver but also in kidneys Low • Decreased Glucose Level
  • 10.
  • 11. TYPES OF HYPOGLYCEMIA DIABETIC HYPOGLYCEMIA Related to low blood glucose level occurring in a person with diabetes mellitus. One of the most common types of hypoglycemia seen in emergency departments and hospitals. NON-DIABETIC HYPOGLYCEMIA Related to some disease, They have further two categories.  REACTIVE HYPOGLYCEMIA  NON-REACTIVE HYPOGLYCEMIA These are also known as causes of Hypoglycemia.
  • 12. CAUSES OF HYPOGLYCEMIA: Reactive hypoglycemia:(Postprandial hypoglycemia)  Reactive hypoglycemia occurs within a few hours after a meal.  Occur in people having sugary stomach Causes: An over-production of insulin an indication for developing diabetes.
  • 13. NON-REACTIVE HYPOGLYCEMIA:(Fasting hypoglycemia) Isn't necessarily related to meal, may be due to an underlying disease. Causes: Some medications, like those used in adults and children with kidney failure excess amounts of alcohol any disorder that affects the liver, heart, or kidneys Anorexia nervosa Rare tumor of pancreas (insulinoma) hormonal deficiency
  • 14.
  • 15.
  • 16. Prevention • Checking blood glucose levels - keep a regular check on blood sugar levels and identify the onset of symptoms. • Eat regularly - keep to your eating routine. • Alcohol - a heavy drinking session can trigger hypoglycemia so prevent alcohol consumption • Exercise - make sure you have eaten some carbo  NOTE Recognize the signs and symptoms of hypoglycemia early because untreated hypoglycemia can lead to: • Seizure • Loss of consciousness • Deathhydrate-rich food before you do any exercise
  • 17. Unawareness of hypoglycemia Overtime repeated episodes of hypoglycemia can lead to unawareness of hypoglycemia Body and brain no longer produce signs and symptoms that warn of low blood sugar level such as shakiness Irregular heart beats when this happen risk of life threaten hypoglycemia is increased.