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SUBARACHNOID HEMORRHAGE
SAH
SAH
• Extravasation of blood into the subarachnoid space
between the pial and arachnoid membranes
• Incidence: aneurysmal SAH 6-8/100.000
ETIOLOGIES
• Trauma: the most common cause
• Spontaneous:
- Ruptured intracranial aneurysms: 70-80%
- AVM: 4-5%
- Certain vasculitides involved the CNS
- Tumor: rarely
- Cerebral artery dissection ( post-traumatic):
carotid & vertebral artery
ETIOLOGIES
• Spontaneous:
- Rupture of a small superfacial artery
- Rupture of an infundibulum
- Coagulation disorders
- Dural sinus thrombosis
- Spinal AVM
- Pretruncal nonaneurysmal SAH
- Drugs, sickle cell anemia, pituitary apoplexy
- No cause: 14-22%
RISK FACTORS
• Hypertension
• Oral contraceptives
• Substance abuse: smoking, cocaine, alcohol
• Diurnal variations in BP
• Pregnancy & parturition
• Advancing age
• LP and/or cerebral angiography in patient with
cerebral aneurysm
• Conditions with an increased incidence of cerebral
aneurysms
CLINICAL FEATURES
• Symtoms: Severe H/A, voimiting, syncope, neck
pain, low back pain,photophobia, LOC, diplopia,
ptosis
• Signs: meningismus, hypertension, focal neurologic
deficit, coma, ocular hemorrhage
RADIOGRAPHIC FINDINGS
• CT-scan: detect > 95% of cases within 48 hrs of
SAH
• Assesses: ventricular size, hematoma, infarct,
amount of blood in cisterns & fissures, predict
aneurysm location
LUMPAR PUNCTURE
• The most sensitive test for SAH
• Xanthochromia and ghost cell
• >100000 RBCs/mm3
• Protein, glucose
RADIOGRAPHIC FINDINGS
• MRI: not sensitive in the first 24-48hrs
• FLAIR MRI: the most sensitive imaging study
for detecting blood in the subarachnoid space
RADIOGRAPHIC FINDINGS
• MRA: sensitive 87% , specificity 92%
• Assesses: aneurysm size, rate and direction of
blood flow, aneurysmal thrombosis and
calcification
RADIOGRAPHIC FINDINGS
• CTA: 97% Aneurysms
• Sfe and effective when used as the initial and
sole imaging study for ruptured and
unruptured cerebral aneurysms
• Evaluation of vasospasm
CEREBRAL ANGIOGRAM
• Gold standard
• 80-85%
• Assesses primary feeding arteries
Hunt & Hess 1968
GRADE Signs and symptoms Survival
1
Asymtomatic or minimal headache and slight neck stiffness 70%
2 Moderate to severe headache; neck stiffness; no neurologic deficit except
cranial nerve palsy
60%
3 Drowsy; minimal neurologic deficit 50%
4 Stuporous; moderate to severe hemiparesis; possibly early decerebrate
rigidity and vegetative disturbances
20%
5 Deep coma; decerebrate rigidity; moribund 10%
Fisher
GRADE Appearance of hemorrhage
1 None evident
2 Less than 1 mm thick
3 More than 1 mm thick
4 Diffuse or none with intraventricular hemorrhage or parenchymal extension
The World Federation of Neurosurgeons
(WFNS)
GRADE GCS Focal neurological deficit
1 15 Absent
2 13-14 Absent
3 13-14 Present
4 7-12 Present or absent
5 <7 Present or absent
TREATMENT
• Calcium channel blockers
• Surgery
• Rebleeding: EACA, AMCA
• Activatad tissue plasminogen

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Subarachnoid hemorrhage

  • 2. SAH • Extravasation of blood into the subarachnoid space between the pial and arachnoid membranes • Incidence: aneurysmal SAH 6-8/100.000
  • 3. ETIOLOGIES • Trauma: the most common cause • Spontaneous: - Ruptured intracranial aneurysms: 70-80% - AVM: 4-5% - Certain vasculitides involved the CNS - Tumor: rarely - Cerebral artery dissection ( post-traumatic): carotid & vertebral artery
  • 4. ETIOLOGIES • Spontaneous: - Rupture of a small superfacial artery - Rupture of an infundibulum - Coagulation disorders - Dural sinus thrombosis - Spinal AVM - Pretruncal nonaneurysmal SAH - Drugs, sickle cell anemia, pituitary apoplexy - No cause: 14-22%
  • 5. RISK FACTORS • Hypertension • Oral contraceptives • Substance abuse: smoking, cocaine, alcohol • Diurnal variations in BP • Pregnancy & parturition • Advancing age • LP and/or cerebral angiography in patient with cerebral aneurysm • Conditions with an increased incidence of cerebral aneurysms
  • 6. CLINICAL FEATURES • Symtoms: Severe H/A, voimiting, syncope, neck pain, low back pain,photophobia, LOC, diplopia, ptosis • Signs: meningismus, hypertension, focal neurologic deficit, coma, ocular hemorrhage
  • 7. RADIOGRAPHIC FINDINGS • CT-scan: detect > 95% of cases within 48 hrs of SAH • Assesses: ventricular size, hematoma, infarct, amount of blood in cisterns & fissures, predict aneurysm location
  • 8. LUMPAR PUNCTURE • The most sensitive test for SAH • Xanthochromia and ghost cell • >100000 RBCs/mm3 • Protein, glucose
  • 9. RADIOGRAPHIC FINDINGS • MRI: not sensitive in the first 24-48hrs • FLAIR MRI: the most sensitive imaging study for detecting blood in the subarachnoid space
  • 10. RADIOGRAPHIC FINDINGS • MRA: sensitive 87% , specificity 92% • Assesses: aneurysm size, rate and direction of blood flow, aneurysmal thrombosis and calcification
  • 11. RADIOGRAPHIC FINDINGS • CTA: 97% Aneurysms • Sfe and effective when used as the initial and sole imaging study for ruptured and unruptured cerebral aneurysms • Evaluation of vasospasm
  • 12. CEREBRAL ANGIOGRAM • Gold standard • 80-85% • Assesses primary feeding arteries
  • 13. Hunt & Hess 1968 GRADE Signs and symptoms Survival 1 Asymtomatic or minimal headache and slight neck stiffness 70% 2 Moderate to severe headache; neck stiffness; no neurologic deficit except cranial nerve palsy 60% 3 Drowsy; minimal neurologic deficit 50% 4 Stuporous; moderate to severe hemiparesis; possibly early decerebrate rigidity and vegetative disturbances 20% 5 Deep coma; decerebrate rigidity; moribund 10%
  • 14. Fisher GRADE Appearance of hemorrhage 1 None evident 2 Less than 1 mm thick 3 More than 1 mm thick 4 Diffuse or none with intraventricular hemorrhage or parenchymal extension
  • 15. The World Federation of Neurosurgeons (WFNS) GRADE GCS Focal neurological deficit 1 15 Absent 2 13-14 Absent 3 13-14 Present 4 7-12 Present or absent 5 <7 Present or absent
  • 16. TREATMENT • Calcium channel blockers • Surgery • Rebleeding: EACA, AMCA • Activatad tissue plasminogen