11. Demographics
• Bimodal distribution
– young individuals with significant trauma
– older individuals that have minor trauma compounded by
degenerative spinal canal narrowing
• It is estimated that 3-25% of all spinal cord injuries occur after
initial traumatic episode due to improper immobilization and
transport.
12. Pathophysiology
• primary injury
– damage to neural tissue due to direct trauma
(usually irreversible)
• secondary injury
– injury to adjacent tissue due to decreased
perfusion
– lipid peroxidation
– free radical / cytokines
– cell apoptosis
13. Spinal Cord Injury
• Spinal shock - transient loss of function below
the level of injury (rarely lasts for more than
48 hours)
• Neurogenic Shock - functional
sympathomectomy, ↓BP & ↓HR (not
responsive to IVH)
14. Classification
• Complete: Absence of sensory & Motor function in lowest
sacral segments after resolution of spinal shock
• Incomplete (preservation of any sensory or motor function –
esp. sacral sparing = big toe flexion, perianal sensation and
bulbocavernosus reflex)
15. Types Of Incomplete Injuries
• Central Cord Syndrome -
hyperextension
• Anterior Cord Syndrome –
flexion/rotation
• Brown-Séquard Syndrome – knife in
the back
• Posterior Cord Syndrome – rare.
Hyperextension/knife
• Cord Concussion = full resolution
within 48hrs
16. Central cord Syndrome
• Hyperextension
• Common in elderly with
preexisting Spondylosis
and cervical stenosis
• Motor: Arm > Leg
weakness
• Sensory: Arms>Legs
• Reflexes: may vary
• Usually sacral sensory
sparing
17.
18. Anterior Cord Syndrome
• Anterior spinal artery
compressed by bone
fragments
• Primarily affects motor
– paralysis
(corticospinal tracts)
• Rarely involves dorsal
columns
• Can occur with AAA
23. • Penetrating Injuries or rotational or
fracture/dislocation
• Ipsilateral motor loss (corticospinal) &
proprioception
• Contralateral sensory (pain/temp) loss
(spinothalamic)
24. Posterior Cord Syndrome
• Rare
• Loss of proprioception
and vibration
• Good prognosis
• Penetrating back
trauma or
hyperextension – with
# vertebral arch
25. Cauda Equina Syndrome
• Not a cord syndrome. Technically a LMN lesion.
• LMN lesion = loss of knee reflexes. Leg weakness
• Bladder/bowel dysfunction
• Loss of anal tone
• Sexual dysfunction
26. • SCIWORA
– (spinal cord injury without radiological
abnormality)
• Dx = no bony or ligamentous injury on x-ray or
CT
– With MRI real “SCIWORA” is rare.
– There is usually cord/ligament injury on MRI
– More common in children – spine more flexible
and less likely to #
– Typically in the cervical region
27. Examination
• Primary survey first
• Cord and vertebral injuries will be picked up on 2° survey
• Head – toe approach
• Look – head, neck, mouth (prevertebral haematoma), paradoxical breathing, lap
seatbelt sign, gross deformity, priapism usually reflects a complete cord injury,
bilateral horner’s syndrome (>T1 and sometimes >T4)
• Feel – feel along the midline of the neck – feeling for deformity and areas of
maximal tenderness. Log Roll
• Examine each modality separately. Head – neck – upper limbs – torso – lower
limbs
• Motor – grading /5
• Sensory – soft touch (dorsal columns) and pain (spinothalamic). ?just pain?
• Reflexes – especially anal tone
• Documentation….
31. Xrays
40 years old man with hx of
falling into a +/- 40m well,
Presented with no motor
activity below Knees,
Sensation is Intact but
reduced below the knees
as well
32.
33. 34 years male involved in an MVA, driver
unrestrained, presented with backpain.
O/E: no neurological fall out but there
was swelling and tendernerness around
L1
34.
35.
36.
37.
38. Initial Management
• Steroids (controversial)
• Neck Immobilization Collar
• Back Immobilization with back support
• Traction with weights and pulleys
39. Cochrane 2012
• Found that methylprednisolone within 8 hrs gave a
significant recovery of motor function
• Contraindications: heavily contaminated wounds,
bowel perforation , sepsis
• Considerations: Type 2 DM, peptic ulcer risk
40. Surgical Management
• Surgical Decompression
• Fixation/ stabilization with a steel rod
• External Immobilization with a brace/cast
42. References
• Louis Solomon et al, 2010, Apley’s System of Orthopaedics
and fratures. 9th edition. Hodder Education
• Derek Moore, 2006. Spinal Cord Injuries. Updated:
8/9/2019.
https://www.orthobullets.com/spine/2006/spinal-cord-
injuries
• Members of the Orthopaedic Department at Oshakati State
Hospital, 2018. Intern Doctors Handbook by Orthopaedic
Department at IHO
• Bracken M, 2012. Steroids for Acute Spinal cord Injury.
Cochrane Review.
https://www.cochrane.org/CD001046/INJ_steroids-acute-
spinal-cord-injury
Editor's Notes
Extends from the medulla oblongata to L1
Lower part is tapered to form the conus Medullaris
Important in determining the level of the injury
Most common at C5,6,7 due to greatest mobility at these levels
The pt with a spinal cord injury will usually have other devastating injuries – therefore cord injuries are to be found on the secondary survey
Steroids used to prevent secondary injury by improving perfusion, inhibiting lipid peroxidation, and decreasing the release of free radicals.
IV dexamethasone 48mg stat, then 8mg tds for 2/7
Neurogenic shock is produced by high spinal injury, which disrupts the sympathetic nerves controlling vasoconstriction. The peripheral vasculature relaxes and becomes profoundly dilated reducing preload and afterload. Even with increased cardiac output the patient cannot maintain an adequate BP/HR
Cauda Equina Syndrome: Consists of lower limb weakness, absent reflexes, impaired sensation and urinary retention.
Herniated Disc Syndrome: displacement of the disc with the escape cartliage
upper extremity motor pathways are more medial(central) which explains why a central cord injury affects the upper extremities more than the lower extremities
Vibration and Proprioception are Spared
CES mainly affects middle-aged individuals, particularly those in their forties and fifties, and presents more often in men
American Spinal Injury Association
Non-haemorrhagic – high signal = oedema
Haemorrhagic (low attenuation areas in the cord oedema
Recovery is low in cases of cord hemorrhage compared to oedema
Length of cord injury: long=bad
IV dexamethasone 48mg stat, then 8mg tds for 2/7
High-dose methylprednisolone steroid therapy is the only pharmacologic therapy shown to have efficacy in a phase three randomized trial when administered within eight hours of injury.
One trial indicates additional benefit by extending the maintenance dose from 24 to 48 hours, if start of treatment must be delayed to between three and eight hours after injury.
There is an urgent need for more randomized trials of pharmacologic therapy for acute spinal cord injury.