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INTRODUCTION TO
CLINICAL
RESEARCH
Mona nafea MD
The goal of scientific research
build scientific
knowledge.
knowledge may
be imperfect or
even quite far
from the truth.
Introduction
The basic principles of the research is to
build knowledge or to improve and update
in every part in our life
Today Brainstorm
The pearl of designing a good research
Significance of good research question
Characteristics of the ideal research question
Brainstorm
Research usually begin
with the research question
To formulate your
question
You should maintain
certain steps
The ideal research question
Focused
Novel
Researchabl
e
Interesting
Feasible
ethical
Specifi
c Relevant
TYPES OF
RESEARCH
QUESTION
1- Quantitative
2-Qualitative
The following table illustrates the differences between
quantitative and qualitative research questions.
This Photo by Unknown Author is licensed under CC BY-SA-NC
Quantitative versus qualitative research
Quantitative research questions

Quantitative research questions usually seek to understand particular social,
familial, or educational experiences or processes that occur in a particular
context and/or location (Marshall & Rossman, 2011).

They can be further categorized into three types:
descriptive,
comparative,
and relationship.
Features of Quantitative research questions
Precise.
population based
Dependent and independent variables, and the research design to be used.
They are usually framed and finalized at the start of the study (Berger, 2015).
Features of Quantitative research questions
establish a link between the research
question and the research design.
Moreover,
these questions are not answerable with
“yes” or “no” responses. As a result,
quantitative research questions don’t use
words such as “is,” “are,” “do,” or “does.”
Qualitative research questions
. Unlike their quantitative counterparts, though,
qualitative research questions are usually
adaptable,
non-directional,
and more flexible (Creswell, 2013).
As a result, studies using these questions
generally aim to “discover,” “explain,” or
“explore.”
Descriptive research questions attempt to describe a
phenomenon.
Emancipatory research questions aim to produce knowledge
that allows for engagement in social action, especially for the
benefit of disadvantaged people.
Evaluative research questions assess the effectiveness of
existing methods or paradigms.
Explanatory research questions seek to expound on a
phenomenon or examine reasons for and associations
between what exists.
Exploratory research questions investigate little-known areas
of a particular topic.
Generative research questions aim to provide new ideas for
the development of theories and actions.
Ideological research questions are used in research that aims
to advance specific ideologies of a position.
5. Construct your research question properly.
Research questions should be structured properly to ensure clarity.
There are several frameworks that you can use for properly constructing a research question. The two
most used frameworks are explained below.
PICOT framework
The PICOT framework was first introduced in 1995 by Richardson et al. Using
PICOT framework; research questions can be constructed to address
elements of the study, including the population to be studied, the expected
outcomes, and the time it takes to achieve the outcome. With these elements,
the framework is more commonly used in clinical research and evidence-
studies.
PICOT
P – population, patients, or problem
I – intervention or indicator being studied
C – comparison group
O – outcome of interest
T – timeframe of the study
EXAMPLES
PANIC DURING COVID-19 PANDEMIC!
A QUALITATIVE INVESTIGATION INTO
THE PSYCHOSOCIAL EXPERIENCES
OF A SAMPLE OF INDIAN PEOPLE
This Photo by Unknown Author is licensed under CC BY
A QUALITATIVE STUDY ABOUT THE MENTAL
HEALTH AND WELLBEING OF OLDER ADULTS
IN THE UK DURING THE COVID-19 PANDEMIC
IMPACT OF THE COVID-19 PANDEMIC
ON MENTAL HEALTH AND WELL-BEING
OF COMMUNITIES: AN EXPLORATORY
QUALITATIVE STUDY PROTOCOL
LENVATINIB VERSUS SORAFENIB IN FIRST-LINE
TREATMENT OF PATIENTS WITH UNRESECTABLE
HEPATOCELLULAR CARCINOMA: A RANDOMIZED
PHASE 3 NON-INFERIORITY TRIAL
This Photo by Unknown Author is licensed under CC BY
QUIZ
HOW CAN WE IMPROVE THE NUMBER OF GRADUATES IN THE COLLEGE OF
ADMINISTRATIVE SCIENCE
(TOO LONG NOT FOCUSED NOT SPECIFIC
Select the best question of all of the following and
comment on the other
Is the remote or online learning helpful for the student
Not specific
Yes or no
Non analytic
Wide
The effect of online learning versus physical on medical student in 5 th year on the
intended learning outcome during the covid era
FOR JOINING MY
IDEAS..FROM
HEART

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intro to clinical research.pptx

  • 2. The goal of scientific research build scientific knowledge. knowledge may be imperfect or even quite far from the truth.
  • 3. Introduction The basic principles of the research is to build knowledge or to improve and update in every part in our life
  • 4. Today Brainstorm The pearl of designing a good research Significance of good research question Characteristics of the ideal research question
  • 5. Brainstorm Research usually begin with the research question To formulate your question You should maintain certain steps
  • 6. The ideal research question Focused Novel Researchabl e Interesting Feasible ethical Specifi c Relevant
  • 8. The following table illustrates the differences between quantitative and qualitative research questions. This Photo by Unknown Author is licensed under CC BY-SA-NC
  • 10. Quantitative research questions  Quantitative research questions usually seek to understand particular social, familial, or educational experiences or processes that occur in a particular context and/or location (Marshall & Rossman, 2011).  They can be further categorized into three types: descriptive, comparative, and relationship.
  • 11. Features of Quantitative research questions Precise. population based Dependent and independent variables, and the research design to be used. They are usually framed and finalized at the start of the study (Berger, 2015).
  • 12. Features of Quantitative research questions establish a link between the research question and the research design. Moreover, these questions are not answerable with “yes” or “no” responses. As a result, quantitative research questions don’t use words such as “is,” “are,” “do,” or “does.”
  • 13. Qualitative research questions . Unlike their quantitative counterparts, though, qualitative research questions are usually adaptable, non-directional, and more flexible (Creswell, 2013). As a result, studies using these questions generally aim to “discover,” “explain,” or “explore.”
  • 14. Descriptive research questions attempt to describe a phenomenon. Emancipatory research questions aim to produce knowledge that allows for engagement in social action, especially for the benefit of disadvantaged people. Evaluative research questions assess the effectiveness of existing methods or paradigms. Explanatory research questions seek to expound on a phenomenon or examine reasons for and associations between what exists. Exploratory research questions investigate little-known areas of a particular topic. Generative research questions aim to provide new ideas for the development of theories and actions. Ideological research questions are used in research that aims to advance specific ideologies of a position.
  • 15. 5. Construct your research question properly. Research questions should be structured properly to ensure clarity. There are several frameworks that you can use for properly constructing a research question. The two most used frameworks are explained below.
  • 16. PICOT framework The PICOT framework was first introduced in 1995 by Richardson et al. Using PICOT framework; research questions can be constructed to address elements of the study, including the population to be studied, the expected outcomes, and the time it takes to achieve the outcome. With these elements, the framework is more commonly used in clinical research and evidence- studies.
  • 17. PICOT P – population, patients, or problem I – intervention or indicator being studied C – comparison group O – outcome of interest T – timeframe of the study
  • 19. PANIC DURING COVID-19 PANDEMIC! A QUALITATIVE INVESTIGATION INTO THE PSYCHOSOCIAL EXPERIENCES OF A SAMPLE OF INDIAN PEOPLE This Photo by Unknown Author is licensed under CC BY
  • 20. A QUALITATIVE STUDY ABOUT THE MENTAL HEALTH AND WELLBEING OF OLDER ADULTS IN THE UK DURING THE COVID-19 PANDEMIC
  • 21. IMPACT OF THE COVID-19 PANDEMIC ON MENTAL HEALTH AND WELL-BEING OF COMMUNITIES: AN EXPLORATORY QUALITATIVE STUDY PROTOCOL
  • 22. LENVATINIB VERSUS SORAFENIB IN FIRST-LINE TREATMENT OF PATIENTS WITH UNRESECTABLE HEPATOCELLULAR CARCINOMA: A RANDOMIZED PHASE 3 NON-INFERIORITY TRIAL This Photo by Unknown Author is licensed under CC BY
  • 23. QUIZ
  • 24. HOW CAN WE IMPROVE THE NUMBER OF GRADUATES IN THE COLLEGE OF ADMINISTRATIVE SCIENCE (TOO LONG NOT FOCUSED NOT SPECIFIC Select the best question of all of the following and comment on the other
  • 25. Is the remote or online learning helpful for the student Not specific Yes or no Non analytic Wide
  • 26. The effect of online learning versus physical on medical student in 5 th year on the intended learning outcome during the covid era

Editor's Notes

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