1. 1) Which of the following congenital cardiovascular malformation is most
commonly associated with maternal rubella infection?
A) Isolated dextrocardia
B) Patent Ductusarteriosus
C) Persistent truncusarteriosos
D) Coarctation of aorta
E) Double Aortic Arch
2) The most common atrial septaldefect (ASD) seen clinically is
A) Common atrium
B) Foramen secundum defect
C) Premature closure of the foramen ovale
D) Persistent truncusarteriosus
E) Probe patency of foramen ovale.
3) Which of the following is responsible for the proper alignment of the
atrioventricular canal?
A) Lateral folds of the embryo
B) Craniocaudal folding of the embryo
C) Programed cell migration
D) Formation of the AP septum
E) Dextral looping.
4) The hepatic sinusoids that can be observed histologically in an adult liver are
derived from the
A) Supracardinal Veins
B) Anterior cardiac veins
C) Posterior cardiac veins
D) Vitelline veins
E) Subcardial veins.
5) Which of the following arterial malformation is very common in premature
infants?
A) Patent ductusarteriosus
B) Coarctation of aorta
C) Right aorta arch
D) Double aortic arch
E) Abnormal origin of the right subclavian artery.
6) Patent DuctusArteriosus. How soon after birth should this murmur normally
disappear?
A) 1-2 months
B) 1-2 weeks
C) 1-2 hours
D) 1-2 days
E) Immediately.

2. 7) The coronary sinsus is a collection of veins joined together to form a large
vessel that collects blood from the myocardium of the heart. It delivers
deoxygenated blood to the right atrium in conjunction with the superior and
inferior vena cava. Embryologically the coronary sinus is derived from which
of the following?
A) Truncusarteriosus
B) Bulbuscordis
C) Primitive ventrible
D) Primitive atrium
E) Sinus venosus
8) The proximal part of the aorta is derived from which of the following?
A) Truncusarteriosus
B) Bulbuscordis
C) Primitive ventricle
D) Primitive atrium
E) Sinus venosus
9) The trabculated part of the right atrium is derived from which of the
following?
A) Truncharteriosus
B) Bulbuscordis
C) Primitive ventricle
D) Primitive atrium
E) Sinus venosus
10)Tricuspid atresia is a cardiac malformation that involved which of the
following septa?
A) Aortiopulmonary septum
B) Atrial septum
C) Atrioventricularseptum
D) Interventericular septum
11)A muscular VSD is a malformation that involves which of the following septa?
A) Aortiopulmonary septum
B) Atrial septum
C) Atrioventricular septum
D) Interventricular septum
12)Tetralogy of fallot is a cardiac malformation that involves which of the
following septa?
A) Aorticopulmonary septum
B) Atrial septum
C) Atrioventricular septum
D) Interventricular septum

3. 13)Transposition of the great arteries is a cardiac malformation that involves
which of the following septa?
A) Aorticopulmonary septum
B) Atrial septum
C) Atricoventricular septum
D) Interventricular septum
14)An insufficient of AV cushion material will result in which of the following?
A) Persistent truncusarteriosus
B) Ebstein anomaly – abnormal
C) Transposition of great arteries
D) Common ventricle
E) Tricuspid atresia
15)A partial development of AP septum results in which of the following?
A) Persistent trancusarteriosus
B) Ebstein anomaly
C) Transposition of great arteries
D) Common ventricle
E) Tricuspid atresia
16)A faulty fusion of the right and left bulbar ridges and AV cushion result in
which of the following?
A) Persistent truncusarterisos
B) Ebstein’s anomaly
C) Transposition of great arteries
D) Common ventricles
E) Membranous VSD
17)The portal vein develops from the
A) Umbilical veins
B) Common cardiac veins
C) Vitelline veins
D) Hepatic veins
18)Which veins follow the yolk stalk into the embryo?
A) Umbilical veins
B) Common cardiac veins
C) Vitelline veins
D) Hepatic veins
E) Portal veins
19)A 17-year old was brought into the ER in the late stages of labor. Her vital
signs are normal, but she appears emaciated. She relates that she is 9 months
pregnant and reports that she has experienced no medical problems during
her pregnancy. Two hours after admission, she gives brith by vaginal delivery

4. to a male infant weighing 3100grams. Despite his low but normal birth
weight. The neonate shows sign of cyanosis shortly after birth. Which of the
following is the most likely explanation for this condition?
A) Coronary arteriovenous fistula
B) Tetralogy of fallot
C) Patent ductusarteriosus
D) ASD
E) VSD
20)A 5 day old baby presents with SOB, Tachypnea, cyanosis, and diaphoresis.
Chest x-ray shows cardiomegaly with increased pulmonary vascularization.
The ECHO shows a single arterial trunk arising from the ventricle. Which best
describes the great vessel abnormality in the patient?
A) Anteriosuperios displacement of the aorticopulmonary septum
B) Failure of the arotopulmonary septum to turn in a spiral
C) Partial development of the aorticopulmonary septum
D) Patent ductusarteriosus
E) Premature closure of foramen ovale.
21)In a newborn nursery, a neonate develops a bluish color when crying. Which
of the following congenital defects may be the cause of cyanosis?
A) Patent foramen ovale
B) Persistent truncusarteriosus
C) Primium type ASD
D) Secundum type ASD
E) VSD
22)Interventricularseptal defect (VSD) is caused by faulty fusion of the right
bulbar, left bulbar ridge and the AV cushion. It results in a condition in which
an opening between the right and left ventricle allows few flow of blood. The
most common VSD seen clinically is
A) Persistent truncusarteriosus
B) Membranous VSD
C) Common ventricle
D) Muscular VSD
E) Premature closure of foramen ovale.
23)A 78 year old man comes to the ER with SOB, dizziness, and fainting spells.
Physical examination shows distended neck veins and peripheral edema. A
plopping sound is heard on auscultation of the heart. An ECHO shows a large
mass arising from the smooth part of the right atrium. The region of the
atrium dervies from which of the following embryonic structures?
A) Bubluscordis
B) Primitive atrium
C) Primitive ventricle
D) Sinus venosus

5. E) Truncusarteriosis
24)A 10 year old by is brought to the ER because of easy fatigability during
exercise. His mother says that he is unable to run more than a few minutes
without developing SOB and that his symptoms have become progressively
worst over the past 6 months. A loud systolic ejection murmur over the
midsternal boarder and a wide fixed split s2 are heard on auscultation.
Which of the following is the most likely diagnosis?
A) Aortic valve stenosis
B) ASD
C) PDA
D) Persistence of foramen ovale
E) VSD
A 35-year-old pregnant diabetic woman shows up at the ER in stage 3 of labor. She
has not received proper prenatal care. A baby girl is born without complications, but
a few hours later the child presents with cyanosis and shortness of breath. The
echocardiography shows a pulmonary artery originated in the posterior left
ventricle and a VSD. Which is the best description for the pulmonary abnormality in
this patient?
Answer Choices:
AAnterosuperior displacement of the aorticopulmonary septum
B Failure of the aortopulmonary septum to turn in a spiral
C Partial development of the aorticopulmonary septum
D Patent ductusarteriosus
E Premature closure of the foramen ovale
[10:55:15 AM] Ragithan: answer is B
A 5-day-old baby boy presents with shortness of breath, tachypnea, cyanosis, and
diaphoresis. Chest X-ray shows cardiomegaly with increased pulmonary
vascularization. The echocardiogram shows a single arterial trunk arising from the
ventricles. Which best describes the great vessel abnormality in this patient?
Answer Choices:
AAnterosuperior displacement of the aorticopulmonary septum
B Failure of the aortopulmonar septum to turn in a spiral
C Partial development of the aorticopulmonary septum
D Patent ductusarteriosus
E Premature closure of the foramen ovale
[10:56:35 AM] Ragithan: ans C

6. A researcher employs site-directed mutagenesis to produce mutations in a gene that
is important for development of the ureteric bud in a rat embryo. The embryo
develops abnormally and is delivered stillborn 20 days later.
A Ascending loop of Henle
B Bowman's capsule
C Collecting duct
D Descending loop of Henle
E Glomerular tuft
A 35-year-old pregnant diabetic woman shows up at the ER in stage 3 of labor. She
has not received proper prenatal care. A baby girl is born without complications, but
a few hours later the child presents with cyanosis and shortness of breath. The
echocardiography shows a pulmonary artery originated in the posterior left
ventricle and a VSD. Which is the best description for the pulmonary abnormality in
this patient?
Answer Choices:
AAnterosuperior displacement of the aorticopulmonary septum
B Failure of the aortopulmonary septum to turn in a spiral
C Partial development of the aorticopulmonary septum
D Patent ductusarteriosus
E Premature closure of the foramen ovale
[10:59:01 AM] Ragithan: remember the researcher q!!!!
[10:59:13 AM] Ragithan: answer to that is C: collecting duct
[10:59:36 AM] Ragithan: anster to pregnant diabetic women is : B failure of the
aortopulmonary...