1. Curriculum vitae-Ester Malka Kitayner
Qualifications and Skills
• Experience in bio-medical research and in bioinformatics. Thorough understanding of state-of-the-art
techniques in proteomics and bioinformatics with strong emphasis on next generation sequencing (NGS)
of RNA/DNA.
• Pipeline development experience of NGS data, including RNA-seq, QC.
• Good understanding of Exome-Seq, DNA methylation, Chip-seq.
• Work experience with protein structure, cancer genomics, annotation and motif analysis.
• Proficiency using NGS algorithms and tools, such as Samtools, Bedtools, Varscan, BWA and so on.
• Strong programing skills in bash (Linux), Python, Perl, C, Matlab, Octave, R.
• Ability to manage parallel tasks, work in deadline-oriented environments, mentoring experience.
Research experience
2015-present Bioinformatics, Bar-Ilan University, Faculty of Medicine, Safed, Israel
shRNA project, data mining
Programming in Perl, R, PHP/JavaScript, usage of bioinformatics programs; scripting;
Databases: NCBI, Ensemble, Cosmic, KEGG, DAVID and so on
2013-2015 Consultant, Molecular modeling and programming. Weizmann Institute of Science (WIS),
Department of Structural Biology, Rehovot, Israel
Programming at the Computer Center of WIS, participation in the project to create a web interface
in PHP/JavaScript language, interaction with SQL.
2010-2012 Intern, Molecular modeling, WIS, Department of Structural Biology, Rehovot, Israel
Programming in Perl, processing and presentation of multiple data with emphasis on efficiency
and user friendliness.
2009-2010 Postdoctoral fellow, Structure analysis and modeling of protein-DNA complexes, WIS,
Department of Structural Biology, Rehovot, Israel
Programming in Perl/Matlab, processing of multiple data with emphasis on efficiency and user
friendliness.
2003-2009 PhD degree Structure analysis of protein-DNA complexes. WIS, Department of Structural
Biology, Rehovot, Israel
Usage of complicated computer programs and programming in Perl for structural analysis based
on multiple experimental data.
2000-2003 MSc degree Structural analysis of the DNA. WIS, Department of Structural Biology,
Rehovot, Israel
Usage of complicated computer programs and programming in Perl for structural analysis based
on multiple experimental data. Development of protein and DNA purification protocols.
1996-1998 Researcher in solid-state physics, The Shubnikov Institute of Crystallography (IC RAS),
Moscow, Russia
Programming in C, with emphasis on efficiency
Education
2016 Course “machine learning” from Stanford
2012 Course on PHP
2009-2010 Postdoctoral fellow, Weizmann Institute of Science (WIS), Department of Structural
Biology, Rehovot, Israel
2003-2009 PhD degree, WIS, Department of Structural Biology, Rehovot, Israel
2000-2003 MSc degree in Bioinformatics, WIS, Department of Structural Biology, Rehovot, Israel
2. 1986-1993 Combined BSc/MSc program in Physics, calculations in hydrodynamics, Moscow Institute
of Physics and Technology, Department of Molecular and Chemical Physics, Moscow, Russia
Technical skills
• Programming languages: Perl, Matlab, Java, Java script, C, Python, PHP, SQL, jQuery, R
• Ready programs: Tophat, Cufflinks, Samtools and so on
• Data bases: NCBI, KEGG, COSMIC, Ensemble and so on
• Others: Photoshop, Gimp, EndNote, Office
• Operating systems: Linux, Windows
Personal characteristics
Ability to learn independently, excellently and quickly, ability to work in a group or autonomously, good
relationships with people, responsible and meticulous
Languages: Hebrew, English, Russian
PUBLICATIONS:
1. Markeeva (Kitayner) MB, Sergeev YA, Ryazantsev YS. "Chemicapillary motion of a drop in a solution
with simultaneous diffusion and chemical-reaction at the interface", Theoretical foundations of chemical
engineering 1995; 29(5):440-445
2. Kitayner M, Rozenberg H, Rabinovich D, Shakked Z. “Structures of the DNA-binding site of Runt-
domain transcription regulators”, Acta Crystallogr D Biol Crystallogr. 2005; 61(Pt 3):236-246.
3. Kitayner M, Rozenberg H, Kessler N, Rabinovich D, Shaulov L, Haran TE, Shakked Z. “Structural
basis of DNA recognition by p53 tetramers”, Mol Cell. 2006; 22(6):741-753.
4. Kitayner M, Rozenberg H, Rohs R, Suad O, Rabinovich D, Honig B, Shakked Z. “Diversity in DNA
recognition by p53 revealed by crystal structures with Hoogsteen base pairs.”, Nat Struct Mol Biol. 2010;
17(4):423-429.
5. Vyas P, Beno I, Xi Z, Kessler N, Kitayner M, Crothers D, Shakked Z, Haran TE. “Structural and
binding properties of DNA response elements bound to p53 proteins and the role of spacer sequences in
p53-DNA interactions.” J Biomol Struct Dyn. 2015; 33: 16-17
Recommendations will be delivered upon request