second part of acute hepatitis causes and presentations

1. ACUTE HEPATITIS
Presented by
Maha Elsabaawy
Associate professor of hepatology
NLI- Menofia university

2.  The liver is the largest organ in the body

3. Inflammation of liver of
could be chronic or acute
when the onset is abrupt

4. Acute hepatitis

5. ACUTE HEPATITIS COULD BE CLASSIFIED ETIOLOGICALLY TO:
Acute viral
hepatitis
Acute non viral
hepatitis

6. ACUTE VIRAL INFECTION MAY BE:
•HAV- HBV HCV HEV
HDV HGVHepatotropic
• INFECTIOUS
MONONUCLEASIS
• CMV
• Herpes simplex
Non
Hepatotropic

27. Significat elevations of ferritin levels released from
destroyed hepatocytes and acute phase reactants
like ceruplasmin and alpha one antitrypsin can be
seen in cases of more severe acute hepatitis

31. ROIE OF LIVER BIOPSY IN ACUTE HEPATITIS
 Controversial because of invasiveness
 Indicated only if needed in treatment decision
 Non invasive measures a big question mark

32. LIVER BIOPSY
 Pathology Diffuse lymphocytic and plasmacytic inflamm
ation, patchy–
piecemeal necrosis, and liver cell degeneration in the for
m of either lytic–ballooning or coagulative–
acidophilic degeneration; AH may be accompanied by a
collapse of the central reticulin fibers
surrounding the hepatocytes; activated Kupffer cells ma
y be filled with phagocytic debris.

43. SEQUALE AND COMPLICATIONS

45. CASE 2
 MIDLLE AGED FEMALE PRESENTED WITH
JAUNDICE . SHE IS HEROIN ADDICT AND WAS
PREGNANT 6 MONTHS AGO