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Predictors of Failure in
Bicuspid Aortic Valve Repair
The key overall conceptual question in
front of the cardiothoracic surgical
community is:
Can we repair virtually every pure
BAV AI presentation as we
presently perform in the mitral
valve repair arena?
BAV - Pathogenesis
Genetics
• Autosomal dominant, variable penetrance
• 9% prevalence in first-degree relatives
• 24% if >1 person affected
• Causal genes largely unknown
• NOTCH1 (9q34.3)
Caliper to measure leaflet Height
Bicuspid aortic valve
Bicuspid aortic valve
Bicuspid aortic valve
Bicuspid aortic valve
Bicuspid aortic valve
Bicuspid aortic valve
Bicuspid aortic valve
Bicuspid aortic valve
Bicuspid aortic valve
Bicuspid aortic valve

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Bicuspid aortic valve

  • 1. Predictors of Failure in Bicuspid Aortic Valve Repair
  • 2. The key overall conceptual question in front of the cardiothoracic surgical community is: Can we repair virtually every pure BAV AI presentation as we presently perform in the mitral valve repair arena?
  • 3.
  • 4. BAV - Pathogenesis Genetics • Autosomal dominant, variable penetrance • 9% prevalence in first-degree relatives • 24% if >1 person affected • Causal genes largely unknown • NOTCH1 (9q34.3)
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  • 44. Caliper to measure leaflet Height