2. Pseudopods / streaks
Finger-like projections of
dark pigment at the
periphery of a lesion
May have small knobs at
the tip
Histologically represent
confluent junctional nests
of melanocytes
3. Confluent junctional nests of
melanocytes of varying sizes and
shapes in a melanoma
from Menzies et al. 2003 An atlas of surface microscopy of pigmented skin lesions
5. Blue-White (Veil)
An irregular indistinct
whitish film
superimposed on an area
of diffuse blue pigment
If overlying the raised
portion of the lesion it
represents dermal
melanin in combination
with compact
orthokeratosis
8. Regression
May occur in:
Melanocytic lesions
Solar lentigines
Seborrheic keratoses
Actinic keratoses
9. Regression characterized by:
Well localized blue-gray dots
or granules
Diffuse multiple blue-gray
dots or granules on a
background of hypomelanosis
Histologically represents
melanin and fibrosis in the
papillary dermis