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ANGINA PECTORIS
By : Ishika Choudhary
ARKA JAIN UNIVERSITRY
Jamshedpur
INTRODUCTION
• It is defined as the chest
pain towards left arm
shoulder due to less
supply of O2more
demand of O2 .
• Due to imbalance
between myocardium O2
requirement and O2
supply .
• TYPES :-stable, unstable,
variant .
Stable angina :
• Typical, classic, common angina.
• Occurs during emotional stress, heavy exercise
• Treating more by rest
• Easily predictable
• Due to atherosclerosis
• Depression of ST-segment in ECG.
Variant angina :
• Prize metal angina
• Occurs in rest also
• Due to spasm of coronary artery
• Treatment : vasodilators like nitroglycerin
• ECG show ST-segment elevation due to transmural
ischaemia .
Unstable angina
• Uncommon  atypical type
• Occurs in exercise and also during rest.
• Prolonged angina may lead to myocardial infarction
• Unpredictable
• Non ST-segment elevation MI .
ETIOLOGY
• Coronary artery disease (CAD) : most common cause
rather than coronary artery spasm that may be due to :-
• Diabetes
• Elevated cholesterol
• High BP
• Smoking
•
Classification of anti-anginal drugs
• Nitrates (nitroglycerin)
• Calcium channel blockers (amlodipine)
• Beta-blockers
• Vasodilators
• Miscellaneous
Drug therapy
• Nitrates : improves blood flow by relaxing and dilating
veins and arteries .
• side effect : headache, increase HR
• Beta-blockers : decrease HR ,BP, and force of contraction
and amount of O2 heart required to pump blood .
• side effect : brandycardia, hallucination .
• Combination therapy :
• Nitrates + beta-blockers -stable angina
• Nitrates + calcium blockers unstable angina
Diagnosis :
• Electrocardiogram
• Stress test
• Chest X-ray
• Blood tests
• Coronary angiography
SYMPTOMS
Management :
• NON-PHARMACEUTICAL APPROACH :
• Quit smoking
• Controlling weight
• PHARMACOLOGICAL APPROACH :
• Nitrates
• Beta-blockers
• Calcium-channel blockers
• SURGICAL APPROACH :
• Angioplasty
• Coronary artery bypass surgery .
Angina pectoris

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Angina pectoris

  • 1. ANGINA PECTORIS By : Ishika Choudhary ARKA JAIN UNIVERSITRY Jamshedpur
  • 2. INTRODUCTION • It is defined as the chest pain towards left arm shoulder due to less supply of O2more demand of O2 . • Due to imbalance between myocardium O2 requirement and O2 supply . • TYPES :-stable, unstable, variant .
  • 3. Stable angina : • Typical, classic, common angina. • Occurs during emotional stress, heavy exercise • Treating more by rest • Easily predictable • Due to atherosclerosis • Depression of ST-segment in ECG.
  • 4. Variant angina : • Prize metal angina • Occurs in rest also • Due to spasm of coronary artery • Treatment : vasodilators like nitroglycerin • ECG show ST-segment elevation due to transmural ischaemia .
  • 5. Unstable angina • Uncommon atypical type • Occurs in exercise and also during rest. • Prolonged angina may lead to myocardial infarction • Unpredictable • Non ST-segment elevation MI .
  • 6. ETIOLOGY • Coronary artery disease (CAD) : most common cause rather than coronary artery spasm that may be due to :- • Diabetes • Elevated cholesterol • High BP • Smoking •
  • 7. Classification of anti-anginal drugs • Nitrates (nitroglycerin) • Calcium channel blockers (amlodipine) • Beta-blockers • Vasodilators • Miscellaneous
  • 8.
  • 9. Drug therapy • Nitrates : improves blood flow by relaxing and dilating veins and arteries . • side effect : headache, increase HR • Beta-blockers : decrease HR ,BP, and force of contraction and amount of O2 heart required to pump blood . • side effect : brandycardia, hallucination . • Combination therapy : • Nitrates + beta-blockers -stable angina • Nitrates + calcium blockers unstable angina
  • 10. Diagnosis : • Electrocardiogram • Stress test • Chest X-ray • Blood tests • Coronary angiography
  • 12. Management : • NON-PHARMACEUTICAL APPROACH : • Quit smoking • Controlling weight • PHARMACOLOGICAL APPROACH : • Nitrates • Beta-blockers • Calcium-channel blockers • SURGICAL APPROACH : • Angioplasty • Coronary artery bypass surgery .