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AN INHERITED DISEASE THAT AFFECTS  THE RED BLOOD CELL BY TINA E. COLEMAN, MPH Overview of Sickle Cell Disease
What is sickle cell disease ? ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],06/04/09 Tina E. Coleman, MPH
Characteristics of  sickle cell disease ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],06/04/09 Tina E. Coleman, MPH
How common is  sickle cell disease? ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],06/04/09 Tina E. Coleman, MPH
Life Expectancy ,[object Object],[object Object],[object Object],[object Object],06/04/09 Tina E. Coleman, MPH
Who does sickle cell disease affect? ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],06/04/09 Tina E. Coleman, MPH
What are the rates for sickle cell disease by ethnic groups?  ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],06/04/09 Tina E. Coleman, MPH
Are there different types of hemoglobin? ,[object Object],[object Object],[object Object],06/04/09 Tina E. Coleman, MPH
Are their different types of  sickle cell disease ? ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],06/04/09 Tina E. Coleman, MPH
How do you get sickle cell disease? ,[object Object],[object Object],[object Object],[object Object],06/04/09 Tina E. Coleman, MPH
How do you inherit the sickle cell gene? ,[object Object],[object Object],06/04/09 Tina E. Coleman, MPH 46 pairs of chromosomes
Genes are messengers ,[object Object],06/04/09 Tina E. Coleman, MPH  This  represents  a gene.  A gene carries messages (DNA )
So what are genes? ,[object Object],[object Object],[object Object],06/04/09 Tina E. Coleman, MPH
Genes determine your hemoglobin type ,[object Object],[object Object],[object Object],[object Object],[object Object],06/04/09 Tina E. Coleman, MPH
How are your hemoglobin genes affected? ,[object Object],[object Object],06/04/09 Tina E. Coleman, MPH
What is sickle cell trait? ,[object Object],[object Object],[object Object],[object Object],[object Object],06/04/09 Tina E. Coleman, MPH
Other things you need to know about  sickle cell trait ,[object Object],[object Object],[object Object],[object Object],[object Object],06/04/09 Tina E. Coleman, MPH
What causes people to have medical problems ? ,[object Object],06/04/09 Tina E. Coleman, MPH
The Red Blood Cell ,[object Object],[object Object],[object Object],06/04/09 Tina E. Coleman, MPH
The Red Blood Cell (cont.) ,[object Object],06/04/09 Tina E. Coleman, MPH
The sickle red blood cell  ,[object Object],[object Object],[object Object],06/04/09 Tina E. Coleman, MPH Note the different distorted shapes of cells with sickle hemoglobin
The sickle shaped red blood cell (cont. 1) ,[object Object],[object Object],[object Object],06/04/09 Tina E. Coleman, MPH Red blood cells clumping and sticking  together is called vaso-occlusion
The sickle shaped red blood cell (cont. 2) ,[object Object],[object Object],[object Object],[object Object],06/04/09 Tina E. Coleman, MPH
What will be covered in the other units? ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],06/04/09 Tina E. Coleman, MPH

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Moodle Overviewof Scd.97to2003 Revised33008

  • 1. AN INHERITED DISEASE THAT AFFECTS THE RED BLOOD CELL BY TINA E. COLEMAN, MPH Overview of Sickle Cell Disease
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Editor's Notes

  1. Welcome to class. This is Unit 1. This PowerPoint presentation will provide a brief overview of sickle cell disease and sickle cell trait. We will go into greater detail on this subject throughout the course. I just wanted to provide you with some very basic information so that you that you can build a solid understanding of the disorder. The picture on the left hand side of the slide is a double helix representing the model for DNA structure. The picture on the right hand of this slide is a picture of an actual red blood cell that has collapsed into a sickle shaped cell. We will learn more about that collapsed red blood cell throughout the course. Sickle Cell Disease 101 06/04/09 Tina E. Coleman, MPH