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Dr. Junaid Shahzad
Post-graduate Resident
Otolaryngology Department
Capital Hospital, Islamabad
 Name: XYZ
 Age: 62
 Gender:Female
 Residence: Islamabad
 Profession: Housewife
 Patient presented to OPD in OCTOBER 2013
with history of DYSPHAGIA- 4 months
 Patient was in normal state of health till 4
months back,when she experienced dysphagia
for solids which progressed slowly and for the
last one month she had dysphagia for liquids as
well.
 There are no alleviating factors
 Dysphagia was also associated with pain
(odynophagia) during swallowing.
 This was also associated with weight loss.
 There is no history of voice change and
breathlessness or otalgia.
 No history of cough or recurrent chest infection.
 Patient was a known hypertensive since the
past decade, but not compliant on
medication.
 Patient was a housewife.
 She has 3 children,2 daughters and 1 son, all
married.
 She lives with her son and daughter in law.
 Patient has been taking anti hypertensive
medications off and on since the past 10
years.
 Sone times takes medications for heartburn.
 No history of SMOKING or ADDICTION
 Belongs to a low socioeconomic back groung.
 An old lady sitting on bed, well oriented in
time,place and person.
 Jaundice
 Clubbing NAD
 Cyanosis
 GPE:
 BP: 50/90 mmHg
 TEMP: Afebrile
 R/R: 18/min
 PULSE: 80/min
 EAR EXAMINATION:
 External ear unremarkable
 Tympanic membranes intact bilaterally with
normal landmarks.
 Hearing test OK
 NOSE:
 Septum, turbinates and nasal mucosa appeared
normal.
 Normal patency
 THROAT:
 Lips, tongue, cheek mucosa, palate, floor of mouth,
gums, teeth, pillars, tonsills and PPW – Normal.
 Tongue mobility, Gag reflex, cough reflex and palatal
movements were normal
 Laryngeal crepitus was present
 Videolaryngoscopy: Revealed
 Epiglottis, Vallecular, Py. Sinuses, aryepiglottic fold,
vocal cords, PPW all appear normal
 Exophytic growth post cricoid area.
 Vocal cords mobile.
 NECK NODES:
 No neck nodes palpable
 CVS: S1+S2 audible in all four areas
 RESP: Normal vesicular breathing
 GIT:
NAD
 CNS:
 Hb: 11.9g/dl
 Na: 138mmol/l
 K: 3.6mmol/l
 Cl: 92mmol/l
 Urea: 22mg/dl
 Creatinine:0.8mg/dl
 DIRECT LARYNGOSCOPY AND
OESOPHAGOSCOPY:
 Exophytic growth involving post cricoid region
and extending to BOTH Pyriform Sinuses,and
Vallecula.
 Sample taken by punch biopsy, sent for
Histopathology.
 Glottis and subglottis clear.
 POORLY DIFFERTIATED NON KERATINIZING
SQUAMOUS CELL CARCINOMA
 IMMUNOHISTOCHEMISTRY:
 P-63- Positive.
 CT SCAN NECK AND CHEST WITH CONTRAST:
 Obliteration and stenosis oropharyngeal cavity
with effacement of vallecula and pyriform
sinuses.
 Enlarged lymph nodes in bilateral parapharyngeal
spaces and Carotid spaces.
 Non specific nodule in right middle lobe adjacent
to mediastinal pleura.
 Poorly differentiated Non keratinizing
Squamous Cell Carcinoma Hypopharynx.
 STAGE: T2 N2C M1
 SENT TO N.O.R.I for
CHEMOTHERAPY/RADIOTHERAPY.
 RADIOTHERAPY
 13 Cycles 39 Gy completted
 SUPPORTIVE
 Magic mouth wash
 Tab chymoral forte BD
 Syp Mucain 2tsf tds
 Syp Brufen 2tsf x tds
 Monthly follow up maintained.
 AT 5 months follow up:
 VIDEOLARYNGOSCOPY:
 Normal.
 DIRECT LARYNGOSCOPY/OESOPHAGOSCOPY:
 Normal.
 CT SCAN NECK AND CHEST WITH CONTRAST:
 Normal.
THANK YOU

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Hypopharyngeal case presentation

  • 1.
  • 2. Dr. Junaid Shahzad Post-graduate Resident Otolaryngology Department Capital Hospital, Islamabad
  • 3.
  • 4.  Name: XYZ  Age: 62  Gender:Female  Residence: Islamabad  Profession: Housewife
  • 5.  Patient presented to OPD in OCTOBER 2013 with history of DYSPHAGIA- 4 months
  • 6.  Patient was in normal state of health till 4 months back,when she experienced dysphagia for solids which progressed slowly and for the last one month she had dysphagia for liquids as well.  There are no alleviating factors  Dysphagia was also associated with pain (odynophagia) during swallowing.  This was also associated with weight loss.  There is no history of voice change and breathlessness or otalgia.  No history of cough or recurrent chest infection.
  • 7.  Patient was a known hypertensive since the past decade, but not compliant on medication.
  • 8.  Patient was a housewife.  She has 3 children,2 daughters and 1 son, all married.  She lives with her son and daughter in law.
  • 9.  Patient has been taking anti hypertensive medications off and on since the past 10 years.  Sone times takes medications for heartburn.  No history of SMOKING or ADDICTION
  • 10.  Belongs to a low socioeconomic back groung.
  • 11.  An old lady sitting on bed, well oriented in time,place and person.  Jaundice  Clubbing NAD  Cyanosis  GPE:  BP: 50/90 mmHg  TEMP: Afebrile  R/R: 18/min  PULSE: 80/min
  • 12.  EAR EXAMINATION:  External ear unremarkable  Tympanic membranes intact bilaterally with normal landmarks.  Hearing test OK  NOSE:  Septum, turbinates and nasal mucosa appeared normal.  Normal patency
  • 13.  THROAT:  Lips, tongue, cheek mucosa, palate, floor of mouth, gums, teeth, pillars, tonsills and PPW – Normal.  Tongue mobility, Gag reflex, cough reflex and palatal movements were normal  Laryngeal crepitus was present  Videolaryngoscopy: Revealed  Epiglottis, Vallecular, Py. Sinuses, aryepiglottic fold, vocal cords, PPW all appear normal  Exophytic growth post cricoid area.  Vocal cords mobile.  NECK NODES:  No neck nodes palpable
  • 14.  CVS: S1+S2 audible in all four areas  RESP: Normal vesicular breathing  GIT: NAD  CNS:
  • 15.  Hb: 11.9g/dl  Na: 138mmol/l  K: 3.6mmol/l  Cl: 92mmol/l  Urea: 22mg/dl  Creatinine:0.8mg/dl
  • 16.  DIRECT LARYNGOSCOPY AND OESOPHAGOSCOPY:  Exophytic growth involving post cricoid region and extending to BOTH Pyriform Sinuses,and Vallecula.  Sample taken by punch biopsy, sent for Histopathology.  Glottis and subglottis clear.
  • 17.  POORLY DIFFERTIATED NON KERATINIZING SQUAMOUS CELL CARCINOMA  IMMUNOHISTOCHEMISTRY:  P-63- Positive.
  • 18.  CT SCAN NECK AND CHEST WITH CONTRAST:  Obliteration and stenosis oropharyngeal cavity with effacement of vallecula and pyriform sinuses.  Enlarged lymph nodes in bilateral parapharyngeal spaces and Carotid spaces.  Non specific nodule in right middle lobe adjacent to mediastinal pleura.
  • 19.  Poorly differentiated Non keratinizing Squamous Cell Carcinoma Hypopharynx.  STAGE: T2 N2C M1
  • 20.  SENT TO N.O.R.I for CHEMOTHERAPY/RADIOTHERAPY.  RADIOTHERAPY  13 Cycles 39 Gy completted  SUPPORTIVE  Magic mouth wash  Tab chymoral forte BD  Syp Mucain 2tsf tds  Syp Brufen 2tsf x tds
  • 21.  Monthly follow up maintained.  AT 5 months follow up:  VIDEOLARYNGOSCOPY:  Normal.  DIRECT LARYNGOSCOPY/OESOPHAGOSCOPY:  Normal.  CT SCAN NECK AND CHEST WITH CONTRAST:  Normal.
  • 22.