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APPLIED ORGANIC
  TECHNOLOGIES
U.S. Primary Manufacturer
    Specialty Alkynes
            &
 Downstream Derivatives
Research
     and
A n a l yt i c a l
Products
 Division
A World Leader in the Production
   of Alkynes and Downstream
              Derivatives
 Using our core synthetic chemistries, we build
 upon our alkyne base to make thousands of
specialty alkynes, olefins, silanes, halogenated
  organics, Grignards and heteroaromatics.
GFS Chemicals has Longevity

85 Years serving companies ranging from
   R&D labs to Pilot Plant to Full Scale
         Production Operations
Organic and Inorganic Expertise
CORE ORGANIC TECHNOLOGY
         BASE                         CORE INORGANIC
                                       TECHNOLOGY
 Liquid Ammonia Chemistry                 BASE
 Halogenation/Dehydrohalgenatio
  n                                    Oxidizers
 Sonogashira Coupling                 Catalysts
 Hydrogenations                       Perchlorates
 Birch Reductions                     Nitrates
 Gabriel Synthesis                     Anhydrous Salts
 Ammonia Borane Technology            Carbonates
 Grignard Synthesis                   Sulfates
 Diels-Alder Reactions
 Organometallic Synthesis (Li, Na,
  Mg, Zn)
Manufacturing Support
 Start up through Commercialization

 Proactive Project Management

 Packaging tailored to your process

 Kilos to Metric Tons

 Integrated Supply Chain

 Additional specifications to meet your
  needs
Alkyne Chemistry

Eliminations           Ethynylations

Sonogashira            Glaser
 Coupling

Cadiot-Chodkiewicz            “Click
 Chemistry”
New Modern Acetylene Handbook
Na & Li/Liquid Ammonia
Chemistry

     Alkylations
     Aminations
     Reductions (Birch, trans)
     Ethynylations

        Halogenations

   Brominations
   Chlorinations
   Iodinations
Heteroaromatics       Halogenated
                       Organics
  Quinolines
  Indoles           Alkynes
 Pyrimidines        Olefins
 Bipyridines        Alkyl
 Phenanthrolin      Aromatic
  es
 Terpyridines
LIQUID AMMONIA CHEMISTRY
ALKYNE CHEMISTRY
Core Synthetic Chemistry
              Specialty
              Alcohols
               Terminal Alkynes

              Internal Alkynes

              cis-/trans- Olefins

               Unsaturated Acids

              Alkynylamines
cis-
             /trans-
             Olefins   Symmetri
                           c
Conjugat
                           &
ed Ene-
                       Asymmet
  ynes
                          ric
                        Diynes
            Alkyne
           Chemistry
Internal
   &
Terminal               Alkynols
Alkynes
            Alkynoic
             Acids
               &
             Esters
Core Synthetic Structures
Alkynes         Olefins
  Aromatic       Cis/trans
  Terminal       En-yne
  Internal       Cyclic
  Alcohols       Grignards
  Ketones        Vinyl
  Acids          Aryl
  Conjugated     Alkyl
Organometallic Chemistry

  Grignard
 Synthesis       Alkyl    Palladium &   Li/Na
                            Copper
      &         Lithium    Catalysis    Amide
Manufacturing
Reactions In Liquid
                                  Ammonia


                                                                      Dehydro-
Ethynylations   Alkylations       Aminations        Reductions      halogenations



                                                Birch       trans
www.GFSOrganics.com for Organic
      Process Chemistry
Domestic Manufacturer with 85+ Years
       of Production Expertise

 ISO 9001:2008 certified
 Certified Member, SOCMA Chemstewards Program
 Member, Chemical & Specialties Management Council
  (CSMC)
 Personal Service and Technical Support
 Flexible Packaging to Meet Your Needs
 On-Site Laboratory with Certified Certificate of Analysis
 Custom Products and Specifications Tailored to Your
  Requirements
 No Minimum Orders
NIST Traceable UV/Vis Validation
           Standards
                  Spectrophotometer
                  Standards

                  Non-Toxic Alternative to
                  Potassium Dichromate

                  Ready-to-Use

                  www.in-spec.com
Quote contact:
     Development@gfschemicals.com
   Start up through Commercialization
   Proactive Project Management
   Packaging Tailored to your Process
   Kilos to Metric Tons
   Integrated Supply Chain
   Additional Specifications to Meet Your Needs

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Organic Overview

  • 1. APPLIED ORGANIC TECHNOLOGIES U.S. Primary Manufacturer Specialty Alkynes & Downstream Derivatives
  • 2. Research and A n a l yt i c a l Products Division
  • 3. A World Leader in the Production of Alkynes and Downstream Derivatives Using our core synthetic chemistries, we build upon our alkyne base to make thousands of specialty alkynes, olefins, silanes, halogenated organics, Grignards and heteroaromatics.
  • 4. GFS Chemicals has Longevity 85 Years serving companies ranging from R&D labs to Pilot Plant to Full Scale Production Operations
  • 5. Organic and Inorganic Expertise CORE ORGANIC TECHNOLOGY BASE CORE INORGANIC TECHNOLOGY  Liquid Ammonia Chemistry BASE  Halogenation/Dehydrohalgenatio n  Oxidizers  Sonogashira Coupling  Catalysts  Hydrogenations  Perchlorates  Birch Reductions  Nitrates  Gabriel Synthesis Anhydrous Salts  Ammonia Borane Technology  Carbonates  Grignard Synthesis  Sulfates  Diels-Alder Reactions  Organometallic Synthesis (Li, Na, Mg, Zn)
  • 6. Manufacturing Support  Start up through Commercialization  Proactive Project Management  Packaging tailored to your process  Kilos to Metric Tons  Integrated Supply Chain  Additional specifications to meet your needs
  • 7. Alkyne Chemistry Eliminations Ethynylations Sonogashira Glaser Coupling Cadiot-Chodkiewicz “Click Chemistry”
  • 9. Na & Li/Liquid Ammonia Chemistry  Alkylations  Aminations  Reductions (Birch, trans)  Ethynylations Halogenations  Brominations  Chlorinations  Iodinations
  • 10. Heteroaromatics Halogenated Organics  Quinolines  Indoles  Alkynes  Pyrimidines  Olefins  Bipyridines  Alkyl  Phenanthrolin  Aromatic es  Terpyridines
  • 13. Core Synthetic Chemistry Specialty Alcohols  Terminal Alkynes Internal Alkynes cis-/trans- Olefins  Unsaturated Acids Alkynylamines
  • 14. cis- /trans- Olefins Symmetri c Conjugat & ed Ene- Asymmet ynes ric Diynes Alkyne Chemistry Internal & Terminal Alkynols Alkynes Alkynoic Acids & Esters
  • 15. Core Synthetic Structures Alkynes Olefins  Aromatic  Cis/trans  Terminal  En-yne  Internal  Cyclic  Alcohols  Grignards  Ketones  Vinyl  Acids  Aryl  Conjugated  Alkyl
  • 16. Organometallic Chemistry Grignard Synthesis Alkyl Palladium & Li/Na Copper & Lithium Catalysis Amide Manufacturing
  • 17. Reactions In Liquid Ammonia Dehydro- Ethynylations Alkylations Aminations Reductions halogenations Birch trans
  • 18. www.GFSOrganics.com for Organic Process Chemistry
  • 19. Domestic Manufacturer with 85+ Years of Production Expertise  ISO 9001:2008 certified  Certified Member, SOCMA Chemstewards Program  Member, Chemical & Specialties Management Council (CSMC)  Personal Service and Technical Support  Flexible Packaging to Meet Your Needs  On-Site Laboratory with Certified Certificate of Analysis  Custom Products and Specifications Tailored to Your Requirements  No Minimum Orders
  • 20. NIST Traceable UV/Vis Validation Standards Spectrophotometer Standards Non-Toxic Alternative to Potassium Dichromate Ready-to-Use www.in-spec.com
  • 21. Quote contact: Development@gfschemicals.com  Start up through Commercialization  Proactive Project Management  Packaging Tailored to your Process  Kilos to Metric Tons  Integrated Supply Chain  Additional Specifications to Meet Your Needs