The document discusses endoscopic retrograde cholangiopancreatography (ERCP)-related perforations, including risk factors, diagnosis, and treatment approaches. It notes that retroperitoneal duodenal perforations are the most common type of ERCP perforation. Conservative management can be successful for treating retroperitoneal perforations, though surgery may be needed in cases of ongoing leakage, sepsis, or fluid collection. Early diagnosis of perforations is important for better outcomes, and suspected cases should be monitored closely and treated promptly with antibiotics and intravenous fluids.