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Restoration of Facial Defects
             Etiology and Basic Principles




               John Beumer III DDS, MS
Division of Advanced Prosthodontics, Biomaterials and
                 Hospital Dentistry
              UCLA School of Dentistry
*The material in this program of instruction is protected by copyright ©. No
part of this program of instruction may be reproduced, recorded, or
transmitted by any means, electronic,digital, photographic, mechanical, etc.
or by any information storage or retrieval system, without prior permission.
Restoration of Facial Defects
A difficult challenge. Both surgical reconstruction and
prosthetic rehabilitation have distinct limitations
v   The surgeon is limited by the complexity of the structures to
     be reconstructed, the availability of tissue, compromise of
     the local vascular bed by radiation in tumor patients and the
     need for visual inspection of oncologic defects

v   The prosthodontist is limited by the properties of the
     materials available, mobility of the tissues adjacent to the
     defects and difficulty of establishing adequate retention for
     large combination facial prostheses.
Table of Contents
v   Etiology of facial defects
v   Presurgical consultation
v   Surgical reconstruction vs prosthetic rehabilitation
v   Materials
v   Alterations at surgery to enhance the prosthetic prognosis
     v   Nasal defects
     v   Orbital defects
     v   Auricular defects
     v   Large midfacial defects
v   Basic principles
     v   Form and symmetry
     v   Surface texture
     v   Lines of juncture
     v   Coloration
Etiology
v Facial   neoplasms
  v Basal cell carcinoma
  v Squamous carcinoma
  v Malignant melanoma

v Craniofacial     anomalies
  v   Microtia
v Trauma
  v   Self inflicted gunshot wounds
Facial Neoplasms
Basal cell carcinoma
   v   Benign
   v   Chronic immunosuppression dramatically
        increases the rate (Berg and Otley, 2002;
        Euvrad et al, 2003; Hasegawa et al,
        2005).
   v   Locally destructive when unattended
   v   Clinical presentations:
         v   Small nodular lesions with a central ulcer
              often covered with a crusted core
Basal cell carcinoma
v Treatment
v Surgical excision
v Mohs’ chemosurgery (Mohs,
   1976; Nelson et al, 1997)
v Radiation
     v   45-60 Gy
Facial Neoplasms
                  Basal cell carcinoma
Large defects result when:
v Tumors are left untreated for a number years
v Extensive recurrences
Facial Neoplasms
Large extensive basal cell carcinoma
Facial Neoplasms
These recurrent basal cell carcinomas extended far
  beyond their original sites and required aggressive re-
  resections resulting in large facial defects.
Facial Neoplasms
              Basal Cell Carcinomas
These recurrent basal cell carcinomas extended far
beyond their original sites and required aggressive re-
resections resulting in large facial defects.
Facial Neoplasms – Basal cell carcinoma
                 Radiation therapy

Before                                        After




  In large tumors such as this one that have invaded
  cartilage, only about 30% fail and require surgery
Basal cell carcinoma
              Radiation Therapy




                        Patient developed a
Postradiation – Note
                        recurrence several
destruction of local
                        years later requiring
structures
                        extensive resection
Basal cell carcinoma
Mohs’ chemosurgery
 v   A tissue fixative is applied to the tumor volume
 v   These tissues are then removed surgically and the specimen is tagged
 v   The specimen is imbedded, sectioned and immediately examined
      microscopically
 v   Persistent tumor is identified, its location confirmed and these tissue
      areas are re-resected on the patient until the specimens are tumor free.
 v   The defects created are irregular and often residual facial structures
      such as portion of the nose remain
Basal cell carcinoma
Mohs’ chemosurgery
 These defects are more challenging to restore
 prosthodontically because:
  v The defect tissues are not lined with skin grafts. This makes it difficult to
     engage the defect so as to enhance retention and the stability of the
     prosthesis
  v Residual facial structures are often displaced making it difficult to restore
     the appearance of size and symmetry of the lost facial structures
Facial neoplasms
Malignant
  v   Usually well differentiated
  v   Can be locally destructive
  v   Advanced tumors can spread to the regional nodes
  v   Squamous carcinomas associated with chronic
       immunosuppression and organ transplantation behave more
Facial neoplasms
              Squamous carcinoma
Treatment
  v Surgery
  v Radiation therapy
Facial neoplasms
            Squamous carcinoma

This tumor has been present for many years
and has destroyed much local tissue
Carcinomas arising from the nasal septum
  These tumors are usually discovered late and require large
  resections of the nose, upper lip and the maxilla.
Facial neoplasms
              Malignant melanoma

These tumors require aggressive surgical excision.
Congenital anomalies
Microtia
    Implant retained auricular prostheses have
    become a viable option. Why?
     v High  levels of implant predictability (Parel and
        Tjellstrom, 1991; Jacobsson et al, 1992; Sugar and
        Beumer, 1994; Roumanas et al, 2002).
     v Consistently excellent esthetic results
     v Fewer and less invasive surgical procedures
     v Reduced cost as compared with surgical reconstruction
Trauma
l   Self inflicted gunshot wounds
Mucormycosis and aspergillosis




This patient required removal of the orbital contents to
control the infection resulting in facial disfigurement.
Surgical reconstruction vs prosthetic
         restoration of large facial defects
v   Many patients prefer that their defects be
     masked with their own tissues rather than
     with a prosthesis
v   Not all patients can accept an artificial
     facial prosthesis
v   Surgical reconstruction is preferred with
     small nasal defects.
v   Acceptable results have been achieved by
     some surgeons with staged reconstruction
     of congenital ear defects (Brent, 2002)

The tip and left ala have been surgically reconstructed in
this patient.
Surgical reconstruction vs prosthetic
 restoration of large facial defects




              Reconstruction of total rhinectomy
              defects is extremely difficult with
              current techniques and the results
              are unpredictable
Surgical reconstruction vs prosthetic
      restoration of large facial defects
Perceptions have changed
regarding facial prostheses
v Improvements in materials used in
   facial prosthetics
v Facial prostheses achieve superior
   esthetic results
v Implant retained facial prostheses
   have achieved wide acceptance
   among surgeons, prosthodontists
   and patients (Flood et al, 1998;
   Markt et al, 2001;Chang et al 2005)

 Prosthesis for a total rhinectomy defect
Patient acceptance – Implant retained
           facial prostheses
Improved because:
 v Quality of the retention
 v Improved esthetics that
    result from accurate
    and repeatable
    positioning
 v Thinner margins
    possible to better
    accommodate mobile
    tissues
 v Ease of maintenance
Surgical reconstruction vs prosthetic
   restoration of large facial defects
Prosthetic restorations are favored
  v When    recurrence of tumor is likely
  v Because of the need to monitor surgical
     site for recurrence
  v With large defects – Reconstruction of
     large defects is difficult, time consuming
     and technically difficult and the outcomes
     are unpredictable
  v When the defect tissues are heavily
     irradiated
Presurgical Consultation




Issues
  v Psychosocial
  v Impressions
  v Photographs
  v Explain  the limits of the prosthetic rehabilitation
  v Brief review of prosthetic care procedures
Presurgical Consultation




Psychosocial issues
  v   Challenges confronting patients
        v   Mortality
        v   Morbidity
               v   Functional impairments
               v   Esthetics
               v   Quality of life - Social function
  v   Challenges confronting the provider
        v   Establish lines of communication
        v   Maintain empathy and compassion while at the same time maintaining
             the ability to motivate the patient to perform needed home care
             procedures
Presurgical Consultation




Psychosocial issues
v   Family members or significant others may be important
     assets in communicating needed information to the patients.
     v   Because these initial consultations are often conducted under
          stressful conditions (the patient has frequently jus been informed of
          the diagnosis and treatment) patients frequently do not absorb all the
          information delivered by the prosthodontist.
v   When the patient and/or their families are having difficulty
     understanding the challenges and their responsibilities for
     home care referral to a clinical psychologist or social worker
     is advised.
Presurgical Consultation




v Impressions
v Photographs
v Explain the benefits and limits of prosthetic rehabilitation
      v   Esthetics – Prostheses in movable tissues
            v   Limits of the physical properties of facial materials
      v   Retention – Skin adhesives vs Implants
v   Brief review of prosthetic care procedures
Materials used for facials prostheses
  Ideal biologic properties of
    processed facial materials
  v   The cured and any released materials should
       not irritate the supporting tissues
  v   The cured and any released materials should
       be non-allergenic
  v   The cured and any released materials should
       be nontoxic
Materials used for facials prostheses
v   Ideal physical and mechanical properties of
     processed facial materials
     v   The cured material should not transfer heat or cold to supporting
          tissues
     v   The cured material should be resistant to abrasion
     v   The cured material should be light weight
     v   The cured material should have high tensile strength
     v   The cured material should have low surface tension and low water
          sorption to resist staining
     v   The cured material should not be dissolved by solvents, primers or
          adhesives
     v   The cured material should be odorless
     v   The cured material should not support the growth of micro-
          organisms
Materials used for facials prostheses
v   Ideal physical and mechanical properties of
     processed facial materials
     v   The cured material should be chemically inert
     v   The cured material should be cleansable with common
          disinfectants without loss of detail at the surface or margins
     v   The cured material should be dimensionally stable
     v   The cured materials’ flexibility should mimic that of the tissues it
          replaces
     v   The cured material should be stable at a range of temperatures
     v   Thin feather edges of the material should not tear
     v   The material should be inexpensive
     v   The material should have lifelike translucency
Materials used for facials prostheses
       v Methyl methacrylate
       v Polyurethanes
       v Silicones
Methyl methacrylate
  Developed in the 1930’s
  Desirable properties
    v Color stable
    v Easy to color
    v Easy to process
    v Margins can be feathered
    v Excellent cosmetic results

  Undesirable properties
    v Rigidity
    v The material transfers heat or
      cold to supporting tissues
Polyurethane elastomers
  Desirable properties
    v Excellent edge strength
    v Margins can be feathered
    v Elasticity
    v Colorability
    v Excellent cosmetic results

  Undesirable properties
    v Not color stable when exposed to
       ultraviolet light secondary to surface
       oxidation
    v Limited life span (3-6 months)
    v Difficult to process particularly under
       humid conditions
    v Poor compatibility with adhesive
       systems
Silicone elastomers*
    Desirable properties
         v Color Stable
         v Easy to process
         v Colorability
         v Reasonable edge strength
         v Margins can be feathered
         v Color stable when exposed to
            ultraviolet light
         v Lifespan – 1-3 years

    Undesirable properties
         v Lack of flexibility
         v Extrinsic coloration tends to wear off

*A detailed discussion of the silicone elastomers can be
found in Powers J and Kiat-annuay. ”Materials” in
Rehabilitation of Facial Defects (Ch 5) in Maxillofacial
Rehabiliation 3rd edition. Eds Beumer J, Marunick M
and Esposito S. Quintessence Publishing Co. Chicago,
Ill 2011. pgs. 260-71
Materials used for facial prostheses
Common problems
 To date, none of the commercial materials satisfy all
 the requirements of the ideal material. Each of the
 materials available has its strengths and weaknesses.
 Even though each type of maxillofacial elastomer has
 its own unique physical and mechanical properties,
 they all share a few common clinical problems which
 can be grouped into two categories.
 v Discoloration of the prosthesis over time
 v Degradation of static and dynamic mechanical
    properties of the polymeric materials.
Materials used for facials prostheses
Future research should concentrate on several
   major goals:
v   Improvement of the physical and mechanical properties of
     existing materials available or development of new alternative
     materials so that replacement materials will behave more like
     human tissue and increase the service life of the prosthesis
v   Identification of color stable coloring agents for coloring facial
     prostheses that are compatible with different types of
     elastomers
v   Development of a scientific method of color matching to
     human skin
v   Development of a scientific color formulation system that
     conforms to the color matching tool to objectively replicate
     human skin shades
Alterations at Surgery to Enhance the
                 Prosthetic Prognosis

 v Nasal   defects

 v Auricular   defects

 v Orbital   defects

 v Large   midfacial defects
Key factor: During resection and
closure surgeon should attempt to
leave adjacent tissues undisturbed
Alterations at Surgery to Enhance the Prosthetic
            Prognosis - Nasal Defects

These are ideal defects. Why?
  v The nasal bones have been resected
  v The nasal labial folds are in normal
     position and of normal depth
  v Cheek contours are undisturbed
  v The upper lip is in normal position and of
     normal contour
  v The floor of the nose has been lined with
     skin
  v The anterior portion of the septum has
     been removed providing good access to
     the defect
Alterations at Surgery to Enhance the
    Prosthetic Prognosis – Nasal Defects




With ideal defects such as these an excellent
cosmetic result can be obtained and the prosthesis
will be well retained
Unfavorable nasal defects
	
                      In this patient,
                      primary closure of
                      wound resulted in
                      deficient lip
                      contours and
                      distortion of left
                      nasolabial fold. The
                      lip is retracted and
                      elevated.
Unfavorable defect.
Note deficient cheek lip contours and superior displacement
of upper lip. Because of distortion of cheeks and retraction
of lip, size and contours of prosthesis were made to be
compatible with existing contours and did not reproduce
preresection nasal size and contour. The angle formed lip
and bottom of the nasal prosthesis is unfavorable
Unfavorable nasal defects
	
                 The nasal bones have
                 been retained and the
                 lip was tied to the nasal
                 mucosa resulting in
                 significant superior
                 retraction of the upper
                 lip. It is not possible to
                 fabricate an acceptable
                 nasal prosthesis on
                 such a patient.
Unfavorable nasal defects
                       	
v   Retention of the nasal bones
v   Retraction of the upper lip




                                Problems created
                                a)   Nasal bones affect position of the nasal tip
                                b)   Lip will always appear too short even if
                                     nasal tip of the prosthesis is shortened
     Result: Unesthetic         c)   Nasal prosthesis will always appear too
     prosthesis                      large because of the lip retraction and
                                     presence of the nasal bones
Unfavorable nasal defects
     Total rhinectomy defects better than partial
                 rhinectomy defects




v Margins are more exposed
v Distortions and displacement of residual nasal
   elements make it difficult to restore proper size and
   symmetry
Alterations at Surgery to Enhance the
                Prosthetic Prognosis




Lining the floor of the nose with a skin graft
  v Limits contracture and elevation of the upper lip
  v Maintains the position of nasolabial folds (the alar
     groove should blend continuously with nasolabial fold)
  v Provides a platform upon which the prosthesis sits
Alterations at surgery to enhance the
         prosthetic prognosis
Orbital defects
  v Linethe orbit with skin
  v Avoid distortion of the eye brow
  v Do not close the defect with flaps
  v Do not retain the eyelids
Alterations at Surgery to Enhance the
           Prosthetic Prognosis
                  Orbital Defects




This orbital exenteration defect is close to ideal. The
entire contents of the orbit have been removed and
the orbital walls lined with skin. However, the position
of the eyebrow is somewhat distorted.
Alterations at Surgery to Enhance the
               Prosthetic Prognosis
                       Orbital Defects




v Lateral facial orbital defect resurfaced with a free flap
   leaving sufficient space for an orbital prosthesis.
v Orbital prosthesis in position.
Alterations at Surgery to Enhance the




The lids were retained following orbital exenteration. There is
insufficient space for an orbital prosthesis. If an orbital
prosthesis is contemplated, they should be removed.
Alterations at Surgery to Enhance the




 This orbital defect was filled with a flap. As a result,
 there is insufficient space for a prosthesis.
Alterations at Surgery to Enhance the




The eyebrow has been altered in this patient
making it more difficult to restore facial
symmetry with an orbital prosthesis
Alterations at surgery to enhance the
         prosthetic prognosis
Ear defects
  v Total auriculectomy defects are easier to
     restore than partial auriculectomy defects
  v Retain the tragus
  v Line the defect with a split thickness skin
     graft
  v Avoid the use of flaps with hair follicles
  v When appropriate, place osseointegrated
     implants
Alterations at surgery to enhance
           the prosthetic prognosis
v Retain the tragus.
v Line site with split thickness skin graft. Why?




The tragus helps hide the anterior margin of the prosthesis
a


     Alterations at surgery to enhance the
              prosthetic prognosis
                Unfavorable ear defects




	
 Large displaced ear fragments. Bilateral symmetry with
  opposite ear cannot be achieved with the prosthesis
Alterations at surgery to enhance the
                   prosthetic prognosis
                      Unfavorable ear defects




Partial ear defects are more difficult to restore because:
   v   Blending margins is more difficult
   v   Bilateral symmetry may be impossible to restore
Alterations at surgery to enhance the
                prosthetic prognosis
                    Unfavorable ear defects




This defect has been lined with a hair bearing scalp flap.
Problems that result:
v   Difficult to use skin adhesives
v   We are unable to place osseointegrated implants through skin with hair
     follicles.
Large Midfacial Defects




v   Skin grafts should be used to line
     v   All raw tissue surfaces
     v   All potential support surfaces
     v   All useful undercuts
v   Attempt to avoid distortion of facial contours adjacent to the
     defect. Avoid primary closure
v   If the upper lip is resected do not attempt to reconstruct it
v   Place implants at the time of surgical ablation
Large Midfacial Defects




Skin grafts should be used to line
  v All raw tissue surfaces
  v All potential support surfaces
  v All useful undercuts
Large Midfacial Defects
                    Favorable vs Unfavorable Defect
                    Skin lined vs nonskin lined defect
         a                                    b




Compare these two defects. In “a” the maxillary sinus is lined with respiratory
mucosa and the septum has been retained. Such a defect cannot be
effectively engaged to help retain, support or stabilize the oral – facial
prostheses. Patient “b” presents with a more favorable defect. The walls of
the maxillary sinus have lined with skin and the septum has been removed.
Hence, the defect can be positively engaged with the facial prosthesis to
facilitate retention, stability and support of the oral – facial prostheses.
Large Midfacial Defects
If the more than half of the upper lip is resected do not
                 attempt to reconstruct it




Problems
vScarring of the reconstructed lip may limit oral access
vThe reconstructed upper lip retracts superiorly and is unable
      to interact effectively with the lower lip to achieve lip
      seal. Speech and saliva control are thereby rendered
      ineffective
vThe cosmetic result is usually unacceptable
Large Midfacial Defects
   a
                                              b




In the previous two patients the non functional
reconstructed lip was overlaid with the facial
prosthesis. Both speech and the esthetic result were
enhanced. In patient (b) a moustache has been used
to camouflage the lip margin.
Large Midfacial Defects
     Placement of implants at the time of tumor resection




v   Lateral portion of defect was restored with a free flap
v   Implants were placed at the time of tumor ablation. When the
     surgical site is healed the implants are fully osseointegrated
     and can be used to retain, stabilized and support the proposed
     oral – facial prostheses
Alterations at surgery to enhance the
                   prosthetic prognosis




Advantages:                               Placement of implants at the time
  vLimits the number of surgeries        of surgical ablation is particularly
  vAccelerates rehabilitation – When     necessary when large facial
  the surgical site is healed and ready   defects are anticipated
  for a prosthesis, the implants are
  osseointegrated
Alterations at surgery to enhance the
                   prosthetic prognosis




Advantages:                               This practice is recommended
  vLimits the number of surgeries        even if the patient is to receive
  vAccelerates rehabilitation – When     postoperative radiation (see
  the surgical site is healed and ready   lecture “Implants in Irradiated
  for a prosthesis, the implants are      Patients”)
  osseointegrated
Basic Principles
v   Form and symmetry


v   Surface texture


v   Lines of juncture



v   Coloration
Form and Symmetry
Issues
  Ideal, and symmetrical contours?
    v Yes,but only if the defect is favorable. However, if there
      are significant distortions of existing facial contours, the
      prosthesis must be tailored accordingly
  Restore bilateral symmetry?
    v Usually   not, particularly if the defect is unfavorable
Form and Symmetry




If the defect is favorable ideal symmetrical
contours are developed. Note the various
sizes, shapes, colors and surface textures
Form and Symmetry
     There were distortions of the existing facial contours in
     both of these patients and the prosthesis was adjusted to
     accommodate to these alterations.




v   Nasal defect with significant        v Patient presented with naso-
     elevation of the lip on the right.   labial fold higher on the right
     Nasal prosthesis in position.        than on left. The note
     Right ala was reduced in size        difference in size of ala
     and elevated to better blend with    between right and left.
     existing contours.
Form and Symmetry
v    Maxillectomy-orbital exenteration
     defect. Note deficient cheek
     contours.

v   Orbital prosthesis in position.
     Symmetry is restored in orbital
     region but not in cheek. The
     contour of zygomatic-malar area
     was not restored. Cheek portion
     was blended with existing cheek
     contours.

v   Note how eyeglass frames and
     shadows cast by them help
     camouflage the defect.
Form and Symmetry




v Contour of columella
v The margin is visible on the upper lip. In most
   patients it is advisable to place margin beneath
   the height of contour of columella
Form and Symmetry




After recontouring the columella and tucking its
margin beneath the tip of nose the appearance of the
prosthesis is improved.
Surface Texture




A simple stipple is required for most ear prostheses.
Surface texture




       v Stipple, lines and grooves
          must be slightly more
          prominent than those on the
          adjacent skin. Why?
       v Some of the surface detail is
          lost during flasking, processing
          and the application of extrinsic
          colorants.
Surface Texture
 Orbital defects require much more surface detail




Large orbital defect. Surface texture of suborbital area and
cheek have been faithfully reproduced. Note that texture of
sculpting is slightly more prominent than skin. This is so because
some detail is lost during processing and extrinsic coloration.
Surface Texture




Proper surface texture for an orbital prosthesis.
Note orbital skin folds are carefully reproduced.
Surface Texture




v   Ideal orbital exenteration defect. Defect is lined with skin,
     eyebrow is in reasonable position and adjacent facial contours
     are not distorted.
v   Orbital prosthesis in position. The globe is properly
     positioned, the lid contours are excellent as is the coloration.
v   What is lacking in this prosthesis?
     v   Sub orbital skin texture has not been reproduced
Margins (Lines of Juncture)
Nasal Defects
  v Blend alar groove with
     nasolabial folds
  v Hide columella margin
     beneath the nasal tip
  v Feather exposed margins
  v Hide exposed margins
     beneath eyeglass frames
Margins – Lines of Juncture




Note the margins (lines of junction) are difficult
 to detect in these patients
Margins (Lines of Juncture)
       A                        B




vTragus hides some of the anterior margin (A)
vWithout a tragus the margin anteriorly is carefully thinned (B)
vEar lobe margins represented by a line in the skin
Margins (Lines of Juncture)

                  v   The eye glass frames
                       help to hide the
                       margins of orbital
                       prostheses

                  v   In this orbital prosthesis
                       the surface texture has
                       been faithfully
                       reproduced
Coloration
                       Intrinsic vs extrinsic




I prefer extrinsic coloration to create and highlight the
surface detail because:
vIt is easier to train residents in this technique as opposed to intrinsic
         coloration methods
vMore consistent esthetic results can be obtained with this method
vThis method is more time efficient. Multiple prostheses can be efficiently
         fabricated with this technique
Coloration - Extrinsic




     v   Shade guides will ensure consistency in
          color and translucence of base.
     v   Coloration is accomplished under
          corrected light conditions.
Coloration - Extrinsic




v   Small ear defect.
v   Prosthesis engages undercuts behind ear and in concha.
v   Completed prosthesis.
Coloration - Extrinsic




	
 Nasal and ear prosthesis. Note excellent color
  matching, surface texture reproduction and marginal
  adaptation.
Coloration - Extrinsic




Shadows and skin creases must be embellished with
paint because of the translucence of the material.
Coloration - Extrinsic




Shadows must be embellished with paint
because of the translucence of the material
Coloration - Intrinsic
 a             b               c




Some clinicians prefer
intrinsic methods              d
because:
v The surface detail does
   not wear off as easily as
   compared to extrinsic
   methods.
v Surface texture is better
   maintained
Coloration - Intrinsic
      a                 b                    c




     Method and Technique:
v   Catalyzed silicone colors (a).          d
v   Painting initial color into mold (b).
v   Each layer is allowed to partially
     catalyze before the subsequent
     one is added (c)
v   Subsequent color layers in mold.
v   Base shade added to mold (d).
Coming soon
vRestoration of nasal defects
vRestoration of auricular defects
vRestoration of orbital defects
vRestoration of midfacial defects
v Visit ffofr.org for hundreds of additional lectures
   on Complete Dentures, Implant Dentistry,
   Removable Partial Dentures, Esthetic Dentistry
   and Maxillofacial Prosthetics.
v The lectures are free and available upon
   registering for the site
v Our objective is to create the best and most
   comprehensive online programs of instruction in
   Prosthodontics

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(New) restoration of facial defects basic priniciples

  • 1. Restoration of Facial Defects Etiology and Basic Principles John Beumer III DDS, MS Division of Advanced Prosthodontics, Biomaterials and Hospital Dentistry UCLA School of Dentistry *The material in this program of instruction is protected by copyright ©. No part of this program of instruction may be reproduced, recorded, or transmitted by any means, electronic,digital, photographic, mechanical, etc. or by any information storage or retrieval system, without prior permission.
  • 2. Restoration of Facial Defects A difficult challenge. Both surgical reconstruction and prosthetic rehabilitation have distinct limitations v The surgeon is limited by the complexity of the structures to be reconstructed, the availability of tissue, compromise of the local vascular bed by radiation in tumor patients and the need for visual inspection of oncologic defects v The prosthodontist is limited by the properties of the materials available, mobility of the tissues adjacent to the defects and difficulty of establishing adequate retention for large combination facial prostheses.
  • 3. Table of Contents v Etiology of facial defects v Presurgical consultation v Surgical reconstruction vs prosthetic rehabilitation v Materials v Alterations at surgery to enhance the prosthetic prognosis v Nasal defects v Orbital defects v Auricular defects v Large midfacial defects v Basic principles v Form and symmetry v Surface texture v Lines of juncture v Coloration
  • 4. Etiology v Facial neoplasms v Basal cell carcinoma v Squamous carcinoma v Malignant melanoma v Craniofacial anomalies v Microtia v Trauma v Self inflicted gunshot wounds
  • 5. Facial Neoplasms Basal cell carcinoma v Benign v Chronic immunosuppression dramatically increases the rate (Berg and Otley, 2002; Euvrad et al, 2003; Hasegawa et al, 2005). v Locally destructive when unattended v Clinical presentations: v Small nodular lesions with a central ulcer often covered with a crusted core
  • 6. Basal cell carcinoma v Treatment v Surgical excision v Mohs’ chemosurgery (Mohs, 1976; Nelson et al, 1997) v Radiation v 45-60 Gy
  • 7. Facial Neoplasms Basal cell carcinoma Large defects result when: v Tumors are left untreated for a number years v Extensive recurrences
  • 8. Facial Neoplasms Large extensive basal cell carcinoma
  • 9. Facial Neoplasms These recurrent basal cell carcinomas extended far beyond their original sites and required aggressive re- resections resulting in large facial defects.
  • 10. Facial Neoplasms Basal Cell Carcinomas These recurrent basal cell carcinomas extended far beyond their original sites and required aggressive re- resections resulting in large facial defects.
  • 11. Facial Neoplasms – Basal cell carcinoma Radiation therapy Before After In large tumors such as this one that have invaded cartilage, only about 30% fail and require surgery
  • 12. Basal cell carcinoma Radiation Therapy Patient developed a Postradiation – Note recurrence several destruction of local years later requiring structures extensive resection
  • 13. Basal cell carcinoma Mohs’ chemosurgery v A tissue fixative is applied to the tumor volume v These tissues are then removed surgically and the specimen is tagged v The specimen is imbedded, sectioned and immediately examined microscopically v Persistent tumor is identified, its location confirmed and these tissue areas are re-resected on the patient until the specimens are tumor free. v The defects created are irregular and often residual facial structures such as portion of the nose remain
  • 14. Basal cell carcinoma Mohs’ chemosurgery These defects are more challenging to restore prosthodontically because: v The defect tissues are not lined with skin grafts. This makes it difficult to engage the defect so as to enhance retention and the stability of the prosthesis v Residual facial structures are often displaced making it difficult to restore the appearance of size and symmetry of the lost facial structures
  • 15. Facial neoplasms Malignant v Usually well differentiated v Can be locally destructive v Advanced tumors can spread to the regional nodes v Squamous carcinomas associated with chronic immunosuppression and organ transplantation behave more
  • 16. Facial neoplasms Squamous carcinoma Treatment v Surgery v Radiation therapy
  • 17. Facial neoplasms Squamous carcinoma This tumor has been present for many years and has destroyed much local tissue
  • 18. Carcinomas arising from the nasal septum These tumors are usually discovered late and require large resections of the nose, upper lip and the maxilla.
  • 19. Facial neoplasms Malignant melanoma These tumors require aggressive surgical excision.
  • 20. Congenital anomalies Microtia Implant retained auricular prostheses have become a viable option. Why? v High levels of implant predictability (Parel and Tjellstrom, 1991; Jacobsson et al, 1992; Sugar and Beumer, 1994; Roumanas et al, 2002). v Consistently excellent esthetic results v Fewer and less invasive surgical procedures v Reduced cost as compared with surgical reconstruction
  • 21. Trauma l Self inflicted gunshot wounds
  • 22. Mucormycosis and aspergillosis This patient required removal of the orbital contents to control the infection resulting in facial disfigurement.
  • 23. Surgical reconstruction vs prosthetic restoration of large facial defects v Many patients prefer that their defects be masked with their own tissues rather than with a prosthesis v Not all patients can accept an artificial facial prosthesis v Surgical reconstruction is preferred with small nasal defects. v Acceptable results have been achieved by some surgeons with staged reconstruction of congenital ear defects (Brent, 2002) The tip and left ala have been surgically reconstructed in this patient.
  • 24. Surgical reconstruction vs prosthetic restoration of large facial defects Reconstruction of total rhinectomy defects is extremely difficult with current techniques and the results are unpredictable
  • 25. Surgical reconstruction vs prosthetic restoration of large facial defects Perceptions have changed regarding facial prostheses v Improvements in materials used in facial prosthetics v Facial prostheses achieve superior esthetic results v Implant retained facial prostheses have achieved wide acceptance among surgeons, prosthodontists and patients (Flood et al, 1998; Markt et al, 2001;Chang et al 2005) Prosthesis for a total rhinectomy defect
  • 26. Patient acceptance – Implant retained facial prostheses Improved because: v Quality of the retention v Improved esthetics that result from accurate and repeatable positioning v Thinner margins possible to better accommodate mobile tissues v Ease of maintenance
  • 27. Surgical reconstruction vs prosthetic restoration of large facial defects Prosthetic restorations are favored v When recurrence of tumor is likely v Because of the need to monitor surgical site for recurrence v With large defects – Reconstruction of large defects is difficult, time consuming and technically difficult and the outcomes are unpredictable v When the defect tissues are heavily irradiated
  • 28. Presurgical Consultation Issues v Psychosocial v Impressions v Photographs v Explain the limits of the prosthetic rehabilitation v Brief review of prosthetic care procedures
  • 29. Presurgical Consultation Psychosocial issues v Challenges confronting patients v Mortality v Morbidity v Functional impairments v Esthetics v Quality of life - Social function v Challenges confronting the provider v Establish lines of communication v Maintain empathy and compassion while at the same time maintaining the ability to motivate the patient to perform needed home care procedures
  • 30. Presurgical Consultation Psychosocial issues v Family members or significant others may be important assets in communicating needed information to the patients. v Because these initial consultations are often conducted under stressful conditions (the patient has frequently jus been informed of the diagnosis and treatment) patients frequently do not absorb all the information delivered by the prosthodontist. v When the patient and/or their families are having difficulty understanding the challenges and their responsibilities for home care referral to a clinical psychologist or social worker is advised.
  • 31. Presurgical Consultation v Impressions v Photographs v Explain the benefits and limits of prosthetic rehabilitation v Esthetics – Prostheses in movable tissues v Limits of the physical properties of facial materials v Retention – Skin adhesives vs Implants v Brief review of prosthetic care procedures
  • 32. Materials used for facials prostheses Ideal biologic properties of processed facial materials v The cured and any released materials should not irritate the supporting tissues v The cured and any released materials should be non-allergenic v The cured and any released materials should be nontoxic
  • 33. Materials used for facials prostheses v Ideal physical and mechanical properties of processed facial materials v The cured material should not transfer heat or cold to supporting tissues v The cured material should be resistant to abrasion v The cured material should be light weight v The cured material should have high tensile strength v The cured material should have low surface tension and low water sorption to resist staining v The cured material should not be dissolved by solvents, primers or adhesives v The cured material should be odorless v The cured material should not support the growth of micro- organisms
  • 34. Materials used for facials prostheses v Ideal physical and mechanical properties of processed facial materials v The cured material should be chemically inert v The cured material should be cleansable with common disinfectants without loss of detail at the surface or margins v The cured material should be dimensionally stable v The cured materials’ flexibility should mimic that of the tissues it replaces v The cured material should be stable at a range of temperatures v Thin feather edges of the material should not tear v The material should be inexpensive v The material should have lifelike translucency
  • 35. Materials used for facials prostheses v Methyl methacrylate v Polyurethanes v Silicones
  • 36. Methyl methacrylate Developed in the 1930’s Desirable properties v Color stable v Easy to color v Easy to process v Margins can be feathered v Excellent cosmetic results Undesirable properties v Rigidity v The material transfers heat or cold to supporting tissues
  • 37. Polyurethane elastomers Desirable properties v Excellent edge strength v Margins can be feathered v Elasticity v Colorability v Excellent cosmetic results Undesirable properties v Not color stable when exposed to ultraviolet light secondary to surface oxidation v Limited life span (3-6 months) v Difficult to process particularly under humid conditions v Poor compatibility with adhesive systems
  • 38. Silicone elastomers* Desirable properties v Color Stable v Easy to process v Colorability v Reasonable edge strength v Margins can be feathered v Color stable when exposed to ultraviolet light v Lifespan – 1-3 years Undesirable properties v Lack of flexibility v Extrinsic coloration tends to wear off *A detailed discussion of the silicone elastomers can be found in Powers J and Kiat-annuay. ”Materials” in Rehabilitation of Facial Defects (Ch 5) in Maxillofacial Rehabiliation 3rd edition. Eds Beumer J, Marunick M and Esposito S. Quintessence Publishing Co. Chicago, Ill 2011. pgs. 260-71
  • 39. Materials used for facial prostheses Common problems To date, none of the commercial materials satisfy all the requirements of the ideal material. Each of the materials available has its strengths and weaknesses. Even though each type of maxillofacial elastomer has its own unique physical and mechanical properties, they all share a few common clinical problems which can be grouped into two categories. v Discoloration of the prosthesis over time v Degradation of static and dynamic mechanical properties of the polymeric materials.
  • 40. Materials used for facials prostheses Future research should concentrate on several major goals: v Improvement of the physical and mechanical properties of existing materials available or development of new alternative materials so that replacement materials will behave more like human tissue and increase the service life of the prosthesis v Identification of color stable coloring agents for coloring facial prostheses that are compatible with different types of elastomers v Development of a scientific method of color matching to human skin v Development of a scientific color formulation system that conforms to the color matching tool to objectively replicate human skin shades
  • 41. Alterations at Surgery to Enhance the Prosthetic Prognosis v Nasal defects v Auricular defects v Orbital defects v Large midfacial defects Key factor: During resection and closure surgeon should attempt to leave adjacent tissues undisturbed
  • 42. Alterations at Surgery to Enhance the Prosthetic Prognosis - Nasal Defects These are ideal defects. Why? v The nasal bones have been resected v The nasal labial folds are in normal position and of normal depth v Cheek contours are undisturbed v The upper lip is in normal position and of normal contour v The floor of the nose has been lined with skin v The anterior portion of the septum has been removed providing good access to the defect
  • 43. Alterations at Surgery to Enhance the Prosthetic Prognosis – Nasal Defects With ideal defects such as these an excellent cosmetic result can be obtained and the prosthesis will be well retained
  • 44. Unfavorable nasal defects In this patient, primary closure of wound resulted in deficient lip contours and distortion of left nasolabial fold. The lip is retracted and elevated.
  • 45. Unfavorable defect. Note deficient cheek lip contours and superior displacement of upper lip. Because of distortion of cheeks and retraction of lip, size and contours of prosthesis were made to be compatible with existing contours and did not reproduce preresection nasal size and contour. The angle formed lip and bottom of the nasal prosthesis is unfavorable
  • 46. Unfavorable nasal defects The nasal bones have been retained and the lip was tied to the nasal mucosa resulting in significant superior retraction of the upper lip. It is not possible to fabricate an acceptable nasal prosthesis on such a patient.
  • 47. Unfavorable nasal defects v Retention of the nasal bones v Retraction of the upper lip Problems created a) Nasal bones affect position of the nasal tip b) Lip will always appear too short even if nasal tip of the prosthesis is shortened Result: Unesthetic c) Nasal prosthesis will always appear too prosthesis large because of the lip retraction and presence of the nasal bones
  • 48. Unfavorable nasal defects Total rhinectomy defects better than partial rhinectomy defects v Margins are more exposed v Distortions and displacement of residual nasal elements make it difficult to restore proper size and symmetry
  • 49. Alterations at Surgery to Enhance the Prosthetic Prognosis Lining the floor of the nose with a skin graft v Limits contracture and elevation of the upper lip v Maintains the position of nasolabial folds (the alar groove should blend continuously with nasolabial fold) v Provides a platform upon which the prosthesis sits
  • 50. Alterations at surgery to enhance the prosthetic prognosis Orbital defects v Linethe orbit with skin v Avoid distortion of the eye brow v Do not close the defect with flaps v Do not retain the eyelids
  • 51. Alterations at Surgery to Enhance the Prosthetic Prognosis Orbital Defects This orbital exenteration defect is close to ideal. The entire contents of the orbit have been removed and the orbital walls lined with skin. However, the position of the eyebrow is somewhat distorted.
  • 52. Alterations at Surgery to Enhance the Prosthetic Prognosis Orbital Defects v Lateral facial orbital defect resurfaced with a free flap leaving sufficient space for an orbital prosthesis. v Orbital prosthesis in position.
  • 53. Alterations at Surgery to Enhance the The lids were retained following orbital exenteration. There is insufficient space for an orbital prosthesis. If an orbital prosthesis is contemplated, they should be removed.
  • 54. Alterations at Surgery to Enhance the This orbital defect was filled with a flap. As a result, there is insufficient space for a prosthesis.
  • 55. Alterations at Surgery to Enhance the The eyebrow has been altered in this patient making it more difficult to restore facial symmetry with an orbital prosthesis
  • 56. Alterations at surgery to enhance the prosthetic prognosis Ear defects v Total auriculectomy defects are easier to restore than partial auriculectomy defects v Retain the tragus v Line the defect with a split thickness skin graft v Avoid the use of flaps with hair follicles v When appropriate, place osseointegrated implants
  • 57. Alterations at surgery to enhance the prosthetic prognosis v Retain the tragus. v Line site with split thickness skin graft. Why? The tragus helps hide the anterior margin of the prosthesis
  • 58. a Alterations at surgery to enhance the prosthetic prognosis Unfavorable ear defects Large displaced ear fragments. Bilateral symmetry with opposite ear cannot be achieved with the prosthesis
  • 59. Alterations at surgery to enhance the prosthetic prognosis Unfavorable ear defects Partial ear defects are more difficult to restore because: v Blending margins is more difficult v Bilateral symmetry may be impossible to restore
  • 60. Alterations at surgery to enhance the prosthetic prognosis Unfavorable ear defects This defect has been lined with a hair bearing scalp flap. Problems that result: v Difficult to use skin adhesives v We are unable to place osseointegrated implants through skin with hair follicles.
  • 61. Large Midfacial Defects v Skin grafts should be used to line v All raw tissue surfaces v All potential support surfaces v All useful undercuts v Attempt to avoid distortion of facial contours adjacent to the defect. Avoid primary closure v If the upper lip is resected do not attempt to reconstruct it v Place implants at the time of surgical ablation
  • 62. Large Midfacial Defects Skin grafts should be used to line v All raw tissue surfaces v All potential support surfaces v All useful undercuts
  • 63. Large Midfacial Defects Favorable vs Unfavorable Defect Skin lined vs nonskin lined defect a b Compare these two defects. In “a” the maxillary sinus is lined with respiratory mucosa and the septum has been retained. Such a defect cannot be effectively engaged to help retain, support or stabilize the oral – facial prostheses. Patient “b” presents with a more favorable defect. The walls of the maxillary sinus have lined with skin and the septum has been removed. Hence, the defect can be positively engaged with the facial prosthesis to facilitate retention, stability and support of the oral – facial prostheses.
  • 64. Large Midfacial Defects If the more than half of the upper lip is resected do not attempt to reconstruct it Problems vScarring of the reconstructed lip may limit oral access vThe reconstructed upper lip retracts superiorly and is unable to interact effectively with the lower lip to achieve lip seal. Speech and saliva control are thereby rendered ineffective vThe cosmetic result is usually unacceptable
  • 65. Large Midfacial Defects a b In the previous two patients the non functional reconstructed lip was overlaid with the facial prosthesis. Both speech and the esthetic result were enhanced. In patient (b) a moustache has been used to camouflage the lip margin.
  • 66. Large Midfacial Defects Placement of implants at the time of tumor resection v Lateral portion of defect was restored with a free flap v Implants were placed at the time of tumor ablation. When the surgical site is healed the implants are fully osseointegrated and can be used to retain, stabilized and support the proposed oral – facial prostheses
  • 67. Alterations at surgery to enhance the prosthetic prognosis Advantages: Placement of implants at the time vLimits the number of surgeries of surgical ablation is particularly vAccelerates rehabilitation – When necessary when large facial the surgical site is healed and ready defects are anticipated for a prosthesis, the implants are osseointegrated
  • 68. Alterations at surgery to enhance the prosthetic prognosis Advantages: This practice is recommended vLimits the number of surgeries even if the patient is to receive vAccelerates rehabilitation – When postoperative radiation (see the surgical site is healed and ready lecture “Implants in Irradiated for a prosthesis, the implants are Patients”) osseointegrated
  • 69. Basic Principles v Form and symmetry v Surface texture v Lines of juncture v Coloration
  • 70. Form and Symmetry Issues Ideal, and symmetrical contours? v Yes,but only if the defect is favorable. However, if there are significant distortions of existing facial contours, the prosthesis must be tailored accordingly Restore bilateral symmetry? v Usually not, particularly if the defect is unfavorable
  • 71. Form and Symmetry If the defect is favorable ideal symmetrical contours are developed. Note the various sizes, shapes, colors and surface textures
  • 72. Form and Symmetry There were distortions of the existing facial contours in both of these patients and the prosthesis was adjusted to accommodate to these alterations. v Nasal defect with significant v Patient presented with naso- elevation of the lip on the right. labial fold higher on the right Nasal prosthesis in position. than on left. The note Right ala was reduced in size difference in size of ala and elevated to better blend with between right and left. existing contours.
  • 73. Form and Symmetry v Maxillectomy-orbital exenteration defect. Note deficient cheek contours. v Orbital prosthesis in position. Symmetry is restored in orbital region but not in cheek. The contour of zygomatic-malar area was not restored. Cheek portion was blended with existing cheek contours. v Note how eyeglass frames and shadows cast by them help camouflage the defect.
  • 74. Form and Symmetry v Contour of columella v The margin is visible on the upper lip. In most patients it is advisable to place margin beneath the height of contour of columella
  • 75. Form and Symmetry After recontouring the columella and tucking its margin beneath the tip of nose the appearance of the prosthesis is improved.
  • 76. Surface Texture A simple stipple is required for most ear prostheses.
  • 77. Surface texture v Stipple, lines and grooves must be slightly more prominent than those on the adjacent skin. Why? v Some of the surface detail is lost during flasking, processing and the application of extrinsic colorants.
  • 78. Surface Texture Orbital defects require much more surface detail Large orbital defect. Surface texture of suborbital area and cheek have been faithfully reproduced. Note that texture of sculpting is slightly more prominent than skin. This is so because some detail is lost during processing and extrinsic coloration.
  • 79. Surface Texture Proper surface texture for an orbital prosthesis. Note orbital skin folds are carefully reproduced.
  • 80. Surface Texture v Ideal orbital exenteration defect. Defect is lined with skin, eyebrow is in reasonable position and adjacent facial contours are not distorted. v Orbital prosthesis in position. The globe is properly positioned, the lid contours are excellent as is the coloration. v What is lacking in this prosthesis? v Sub orbital skin texture has not been reproduced
  • 81. Margins (Lines of Juncture) Nasal Defects v Blend alar groove with nasolabial folds v Hide columella margin beneath the nasal tip v Feather exposed margins v Hide exposed margins beneath eyeglass frames
  • 82. Margins – Lines of Juncture Note the margins (lines of junction) are difficult to detect in these patients
  • 83. Margins (Lines of Juncture) A B vTragus hides some of the anterior margin (A) vWithout a tragus the margin anteriorly is carefully thinned (B) vEar lobe margins represented by a line in the skin
  • 84. Margins (Lines of Juncture) v The eye glass frames help to hide the margins of orbital prostheses v In this orbital prosthesis the surface texture has been faithfully reproduced
  • 85. Coloration Intrinsic vs extrinsic I prefer extrinsic coloration to create and highlight the surface detail because: vIt is easier to train residents in this technique as opposed to intrinsic coloration methods vMore consistent esthetic results can be obtained with this method vThis method is more time efficient. Multiple prostheses can be efficiently fabricated with this technique
  • 86. Coloration - Extrinsic v Shade guides will ensure consistency in color and translucence of base. v Coloration is accomplished under corrected light conditions.
  • 87. Coloration - Extrinsic v Small ear defect. v Prosthesis engages undercuts behind ear and in concha. v Completed prosthesis.
  • 88. Coloration - Extrinsic Nasal and ear prosthesis. Note excellent color matching, surface texture reproduction and marginal adaptation.
  • 89. Coloration - Extrinsic Shadows and skin creases must be embellished with paint because of the translucence of the material.
  • 90. Coloration - Extrinsic Shadows must be embellished with paint because of the translucence of the material
  • 91. Coloration - Intrinsic a b c Some clinicians prefer intrinsic methods d because: v The surface detail does not wear off as easily as compared to extrinsic methods. v Surface texture is better maintained
  • 92. Coloration - Intrinsic a b c Method and Technique: v Catalyzed silicone colors (a). d v Painting initial color into mold (b). v Each layer is allowed to partially catalyze before the subsequent one is added (c) v Subsequent color layers in mold. v Base shade added to mold (d).
  • 93. Coming soon vRestoration of nasal defects vRestoration of auricular defects vRestoration of orbital defects vRestoration of midfacial defects
  • 94. v Visit ffofr.org for hundreds of additional lectures on Complete Dentures, Implant Dentistry, Removable Partial Dentures, Esthetic Dentistry and Maxillofacial Prosthetics. v The lectures are free and available upon registering for the site v Our objective is to create the best and most comprehensive online programs of instruction in Prosthodontics