The document discusses using mobile phones to measure lung function through sound analysis of breath. It describes developing a method called SpiroSmart that uses a phone's microphone to record breath sounds and analyze the audio signals to estimate lung function metrics like FEV1 and FVC. An initial study was conducted where pulmonologists evaluated lung function curves generated by SpiroSmart for 10 patients and were able to accurately diagnose 64% of cases, with 10% needing further tests and 14% receiving false positives. The results suggest SpiroSmart may be able to provide basic lung function assessments using only a smartphone.
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Mobilizing mHealth: interdisciplinary computer science and engineering
1. eric c. larson | eclarson.com
interdisciplinary computer science and engineering
mobilizing mhealth
Assistant Professor Computer Science and Engineering
Wednesday, September 11, 13
64. study enrollment
participants 52
18-75 years old, mostly healthy18-75 years old, mostly healthy
study a
participants 10
12-17 years old, mixed healthy/abnormal12-17 years old, mixed healthy/abnormal
study b
Wednesday, September 11, 13
65. study enrollment
participants 52
18-75 years old, mostly healthy18-75 years old, mostly healthy
study a
participants 10
12-17 years old, mixed healthy/abnormal12-17 years old, mixed healthy/abnormal
study b
participants 56
10-69 years old, mostly abnormal10-69 years old, mostly abnormal
study c
enrolledby
pulmonologists
Wednesday, September 11, 13
121. neonatal jaundice in the US
kernicterus:
21
hazardous
jaundice: 1158
extreme jaundice:
2,317
severe jaundice: 35,000
phototherapy: 290,000
visible jaundice: 3.5 million
births/year: 4.1 million
Wednesday, September 11, 13
122. Method Accuracy Disadvantages
TSB
Gold standard
(r=1.0)
Painful, costly,
inconvenient, delayed
TcB
Accurate
(r= 0.75 -0.93)
Meter = $7000
tips $5
unavailable in most
physician offices
Visual assessment
(provider or parent)
not accurate
(r= 0.36 - 0.7),
underestimates
severity
No standardization
lighting, pigmentation
Wednesday, September 11, 13
131. • near term: screening
Wednesday, September 11, 13
132. • near term: screening
• medium term: TSB study
Wednesday, September 11, 13
133. • near term: screening
• medium term: TSB study
• long term: developing world
Wednesday, September 11, 13
134. • near term: screening
• medium term: TSB study
• long term: developing world
“in many resource poor nations,
hyperbilirubinemia is the second or
third leading cause of infant
mortality and disability”
Wednesday, September 11, 13
142. activity detection
elder care
daily activity logs
congestive heart failure
health markers via phone
blood pressure
pulse oximetry
stress
opportunistic sensing
pain management
detecting circulation
Wednesday, September 11, 13
143. activity detection
elder care
daily activity logs
congestive heart failure
health markers via phone
blood pressure
pulse oximetry
stress
opportunistic sensing
pain management
detecting circulation
developing world
Wednesday, September 11, 13
144. take away
• CSE has a large role in the coming evolution of
mHealth, equal to doctors
• sensing and clinical utility
• deploy in clinic, deploy in world, then release
• ... look for a new mobile application sensing
course ...
Wednesday, September 11, 13
145. eric c. larson | eclarson.com
interdisciplinary computer science and engineering
mobilizing mhealth
Assistant Professor Computer Science and Engineering
eclarson.com
eclarson@lyle.smu.edu
@ec_larson Thank You!
Wednesday, September 11, 13