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big data, small data:
the future of sensing in health and
sustainability

eric c. larson | eclarson.com
Assistant Professo...
easy to get
hard to get

easy to get
application

hard to get

easy to get
application

application
hard to get

easy to get
data
data = knowledge
data

you
personalization

data

you
personalization

data

you
feedback
health and sustainability
small data in
health and sustainability
small data in
health and sustainability
sensing
you
small data in
health and sustainability
sensing

sensing
you
stakeholders

you
sustainability and water
sustainability and water

lake mead 1983
lake mead 2011
lake mead 2011
$2,994.83
eco-feedback

Geographic Comparisons

Dashboards

Metaphorical Unit Designs

Recommendations
eco-feedback

Geographic Comparisons

Dashboards

Metaphorical Unit Designs

Recommendations
types of eco-feedback

Annual % Savings

20%

20%

15%

12%

10%

6.8%

5%

8.4%

9.2%

3.8%
0%

Enhanced
1
Billing

Web
2...
types of eco-feedback

Annual % Savings

20%

20%

15%

aggregate

12%

10%

6.8%

5%

8.4%

9.2%

3.8%
0%

Enhanced
1
Bil...
types of eco-feedback

Annual % Savings

20%

disaggregated

20%

15%

aggregate

12%

10%

6.8%

5%

8.4%

9.2%

3.8%
0%
...
on average, a consumer can
save 15-25%
bathroom usage
leaky flapper valve
bathroom usage
mobile health
m health
iPhone 9

M

Now with iColon.

> slide to unlock
the promise of mhealth:
the promise of mhealth:
revolutionize medicine
the promise of mhealth:
revolutionize medicine
eliminate doctor visits
the promise of mhealth:
revolutionize medicine
eliminate doctor visits
remote / automatic diagnosis
the promise of mhealth:
revolutionize medicine
eliminate doctor visits
remote / automatic diagnosis
equalize developing co...
the promise of mhealth:
revolutionize medicine
eliminate doctor visits
remote / automatic diagnosis
equalize developing co...
the promise of mhealth:
revolutionize medicine
eliminate doctor visits
remote / automatic diagnosis
equalize developing co...
heart rate
zombie run

fitness trainer

stress check

current mhealth

glucose buddy
heart rate

stress check

zombie run

current mhealth
43,000 apps for health on the app store

fitness trainer

glucose bud...
heart rate

stress check

zombie run

current mhealth
43,000 apps for health on the app store
96% are for calorie counting...
heart rate

stress check

zombie run

current mhealth
43,000 apps for health on the app store
96% are for calorie counting...
heart rate

stress check

zombie run

current mhealth
43,000 apps for health on the app store
96% are for calorie counting...
consider physician’s needs
consider physician’s needs
connecting with patient
consider physician’s needs
connecting with patient
tracking baselines
consider physician’s needs
connecting with patient
tracking baselines
personalized trending data
consider physician’s needs
connecting with patient
tracking baselines
personalized trending data
managing chronic disease
consider physician’s needs
connecting with patient
tracking baselines
personalized trending data
managing chronic disease
...
mhealth and chronic disease
management
mhealth and chronic disease
management
compliance?
cost?
doctor patient?
data reliability?
compliance
compliance
baseline

sensor

quantity
phone as a sensor
baseline

sensor

quantity
phone as a sensor
baseline

embedded
sensors

sensor

quantity
phone as a sensor
baseline

embedded
sensors

sensor

estimated
quantity

processing
accelerometer
gyroscope
magnetometer /compass
dual camera / flash
1+ microphones
proximity sensor
capacitive sensor
gps
mot...
compliance++;
cost--;
dr_pat *= 10;

accelerometer
gyroscope
magnetometer /compass
dual camera / flash
1+ microphones
proxi...
accelerometer
gyroscope
magnetometer /compass
dual camera / flash
1+ microphones
compliance++;
proximity sensor
cost--;
cap...
what can the mobile phone
sense with clinical accuracy?
what can the mobile phone
sense with clinical accuracy?
which chronic diseases
should be targeted first?
volume

flow

spirometry testing

time

volume
volume

flow

spirometry testing

time

volume
volume

flow

spirometry testing

time

volume
spirometry
spirometry
standard of care for:
spirometry
standard of care for:
asthma
COPD
post-transplant breathing
cystic fibrosis
home spirometry
home spirometry

!

faster detection
rapid recovery
trending
challenges with

home spirometry

high cost barrier
patient compliance
less coaching
limited integration
flow rate
volume

airflow
sensor

lung function
flow rate
volume

airflow
sensor

sound
pressure

microphone

lung function
flow rate
volume

airflow
sensor

estimated
lung function

sound
pressure

microphone

processing
SpiroSmart
availability
cost
portability
more effective coaching interface
integrated uploading
Using SpiroSmart
SpiroSmart
SpiroSmart
within ~5-7% of a real spirometer

phone app

doctor visit
appropriate for
trending and screening
global health non-profit
global health non-profit

patient and doctors
global health non-profit

patient and doctors

pharmaceutical drug trials
currently undergoing
FDA 510k device approval
diagnostic deployment in India
started in January
other applications in health?
mhealth and newborns?
neonatal jaundice in the US
kernicterus:
21

hazardous
jaundice: 1158
extreme jaundice:
2,317
severe jaundice: 35,000

pho...
Method

Accuracy

Disadvantages

TSB

Gold standard
(r=1.0)

Painful, costly,
inconvenient, delayed

Accurate
(r= 0.75 -0....
bilirubin
level in blood

blood
draw

jaundice level
bilirubin
level in blood

blood
draw

yellowness

camera

jaundice level
bilirubin
level in blood

blood
draw

estimated
jaundice level

yellowness

camera

processing
bilicam
bilicam

correlates with TSB at 0.84
TcB correlates anywhere from 0.71 to 0.9
mobile apps are poised to
	 	 	 	 	 take over the market

nokia x-challenge:
grand prize:
mobile device that
monitors vita...
the future of mHealth?
the future of mHealth?
• new sensors will be integrated into phones
the future of mHealth?
• new sensors will be integrated into phones
• health sensing and mobile phone manufacturing
will b...
the future of mHealth?
• new sensors will be integrated into phones
• health sensing and mobile phone manufacturing
will b...
the future of mHealth?
• new sensors will be integrated into phones
• health sensing and mobile phone manufacturing
will b...
the future of mHealth?
• new sensors will be integrated into phones
• health sensing and mobile phone manufacturing
will b...
the future of mHealth?
• new sensors will be integrated into phones
• health sensing and mobile phone manufacturing
will b...
the future of mHealth?
• new sensors will be integrated into phones
• health sensing and mobile phone manufacturing
will b...
what app makes a phone a
	 	 	 medical device?
what app makes a phone a
	 	 	 medical device?
apps that transform a phone
or connect to a medical sensor
what app makes a phone a
	 	 	 medical device?
apps that transform a phone
or connect to a medical sensor
apps that contro...
what app makes a phone a
	 	 	 medical device?
apps that transform a phone
or connect to a medical sensor
apps that contro...
what app makes a phone a
	 	 	 medical device?
apps that transform a phone
or connect to a medical sensor
apps that contro...
m

ay

be

ye

s

ye

s

ye

s

	 what app makes a phone a
	 	 	 medical device?
apps that transform a phone
or connect to...
m

ay

be

ye

s

ye

s

ye

s

	 what app makes a phone a
	 	 	 medical device?
apps that transform a phone
or connect to...
m

ay

be

m

ay

be

ye

s

ye

s

ye

s

	 what app makes a phone a
	 	 	 medical device?
apps that transform a phone
or...
what app makes a phone a
	 	 	 medical device?

we will see?
some approved apps
some approved apps
some approved apps
some approved apps
some approved apps
my take
eclarson.com
eclarson@lyle.smu.edu
> slide to unlock
@ec_larson

Thank You!
big data, small data:
the future of sensing in
health and sustainability

eclarson.com
eclarson@lyle.smu.edu
> slide to un...
big data, small data:
the future of sensing in
health and sustainability

eclarson.com
eclarson@lyle.smu.edu
@ec_larson

c...
Big Data, Small Data
Big Data, Small Data
Big Data, Small Data
Big Data, Small Data
Big Data, Small Data
Big Data, Small Data
Big Data, Small Data
Big Data, Small Data
Big Data, Small Data
Big Data, Small Data
Big Data, Small Data
Big Data, Small Data
Big Data, Small Data
Big Data, Small Data
Big Data, Small Data
Big Data, Small Data
Big Data, Small Data
Big Data, Small Data
Big Data, Small Data
Big Data, Small Data
Big Data, Small Data
Big Data, Small Data
Big Data, Small Data
Big Data, Small Data
Big Data, Small Data
Big Data, Small Data
Big Data, Small Data
Big Data, Small Data
Big Data, Small Data
Big Data, Small Data
Big Data, Small Data
Big Data, Small Data
Big Data, Small Data
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The future of sensing in sustainability and health

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Big Data, Small Data

  1. 1. big data, small data: the future of sensing in health and sustainability eric c. larson | eclarson.com Assistant Professor Computer Science and Engineering
  2. 2. easy to get
  3. 3. hard to get easy to get
  4. 4. application hard to get easy to get
  5. 5. application application hard to get easy to get
  6. 6. data
  7. 7. data = knowledge
  8. 8. data you
  9. 9. personalization data you
  10. 10. personalization data you feedback
  11. 11. health and sustainability
  12. 12. small data in health and sustainability
  13. 13. small data in health and sustainability sensing you
  14. 14. small data in health and sustainability sensing sensing you stakeholders you
  15. 15. sustainability and water
  16. 16. sustainability and water lake mead 1983
  17. 17. lake mead 2011
  18. 18. lake mead 2011
  19. 19. $2,994.83
  20. 20. eco-feedback Geographic Comparisons Dashboards Metaphorical Unit Designs Recommendations
  21. 21. eco-feedback Geographic Comparisons Dashboards Metaphorical Unit Designs Recommendations
  22. 22. types of eco-feedback Annual % Savings 20% 20% 15% 12% 10% 6.8% 5% 8.4% 9.2% 3.8% 0% Enhanced 1 Billing Web 2 Based Daily 3 Feedback Realtime 4 Feedback Appliance Appliance Level 5 Untitled 1 + Personalized Level Feedback Based on 36 studies between 1995-2010. Summarized by Ehrhardt-Matinez et al.
 >20% reduction: Gardner et al. (2008) and Laitner et al. (2009)
  23. 23. types of eco-feedback Annual % Savings 20% 20% 15% aggregate 12% 10% 6.8% 5% 8.4% 9.2% 3.8% 0% Enhanced 1 Billing Web 2 Based Daily 3 Feedback Realtime 4 Feedback Appliance Appliance Level 5 Untitled 1 + Personalized Level Feedback Based on 36 studies between 1995-2010. Summarized by Ehrhardt-Matinez et al.
 >20% reduction: Gardner et al. (2008) and Laitner et al. (2009)
  24. 24. types of eco-feedback Annual % Savings 20% disaggregated 20% 15% aggregate 12% 10% 6.8% 5% 8.4% 9.2% 3.8% 0% Enhanced 1 Billing Web 2 Based Daily 3 Feedback Realtime 4 Feedback Appliance Appliance Level 5 Untitled 1 + Personalized Level Feedback Based on 36 studies between 1995-2010. Summarized by Ehrhardt-Matinez et al.
 >20% reduction: Gardner et al. (2008) and Laitner et al. (2009)
  25. 25. on average, a consumer can save 15-25%
  26. 26. bathroom usage
  27. 27. leaky flapper valve bathroom usage
  28. 28. mobile health
  29. 29. m health
  30. 30. iPhone 9 M Now with iColon. > slide to unlock
  31. 31. the promise of mhealth:
  32. 32. the promise of mhealth: revolutionize medicine
  33. 33. the promise of mhealth: revolutionize medicine eliminate doctor visits
  34. 34. the promise of mhealth: revolutionize medicine eliminate doctor visits remote / automatic diagnosis
  35. 35. the promise of mhealth: revolutionize medicine eliminate doctor visits remote / automatic diagnosis equalize developing countries
  36. 36. the promise of mhealth: revolutionize medicine eliminate doctor visits remote / automatic diagnosis equalize developing countries
  37. 37. the promise of mhealth: revolutionize medicine eliminate doctor visits remote / automatic diagnosis equalize developing countries
  38. 38. heart rate zombie run fitness trainer stress check current mhealth glucose buddy
  39. 39. heart rate stress check zombie run current mhealth 43,000 apps for health on the app store fitness trainer glucose buddy
  40. 40. heart rate stress check zombie run current mhealth 43,000 apps for health on the app store 96% are for calorie counting & exercise fitness trainer glucose buddy
  41. 41. heart rate stress check zombie run current mhealth 43,000 apps for health on the app store 96% are for calorie counting & exercise 4% are remote monitoring fitness trainer glucose buddy
  42. 42. heart rate stress check zombie run current mhealth 43,000 apps for health on the app store 96% are for calorie counting & exercise 4% are remote monitoring ~100 are cleared by the FDA fitness trainer glucose buddy
  43. 43. consider physician’s needs
  44. 44. consider physician’s needs connecting with patient
  45. 45. consider physician’s needs connecting with patient tracking baselines
  46. 46. consider physician’s needs connecting with patient tracking baselines personalized trending data
  47. 47. consider physician’s needs connecting with patient tracking baselines personalized trending data managing chronic disease
  48. 48. consider physician’s needs connecting with patient tracking baselines personalized trending data managing chronic disease 30% of all US healthcare spending is on chronic disease
  49. 49. mhealth and chronic disease management
  50. 50. mhealth and chronic disease management compliance? cost? doctor patient? data reliability?
  51. 51. compliance
  52. 52. compliance
  53. 53. baseline sensor quantity
  54. 54. phone as a sensor baseline sensor quantity
  55. 55. phone as a sensor baseline embedded sensors sensor quantity
  56. 56. phone as a sensor baseline embedded sensors sensor estimated quantity processing
  57. 57. accelerometer gyroscope magnetometer /compass dual camera / flash 1+ microphones proximity sensor capacitive sensor gps motorized actuator wireless antenna (s)
  58. 58. compliance++; cost--; dr_pat *= 10; accelerometer gyroscope magnetometer /compass dual camera / flash 1+ microphones proximity sensor capacitive sensor gps motorized actuator wireless antenna (s)
  59. 59. accelerometer gyroscope magnetometer /compass dual camera / flash 1+ microphones compliance++; proximity sensor cost--; capacitive sensor dr_pat *= 10; gps motorized actuator data reliability? wireless antenna (s)
  60. 60. what can the mobile phone sense with clinical accuracy?
  61. 61. what can the mobile phone sense with clinical accuracy? which chronic diseases should be targeted first?
  62. 62. volume flow spirometry testing time volume
  63. 63. volume flow spirometry testing time volume
  64. 64. volume flow spirometry testing time volume
  65. 65. spirometry
  66. 66. spirometry standard of care for:
  67. 67. spirometry standard of care for: asthma COPD post-transplant breathing cystic fibrosis
  68. 68. home spirometry
  69. 69. home spirometry ! faster detection rapid recovery trending
  70. 70. challenges with home spirometry high cost barrier patient compliance less coaching limited integration
  71. 71. flow rate volume airflow sensor lung function
  72. 72. flow rate volume airflow sensor sound pressure microphone lung function
  73. 73. flow rate volume airflow sensor estimated lung function sound pressure microphone processing
  74. 74. SpiroSmart availability cost portability more effective coaching interface integrated uploading
  75. 75. Using SpiroSmart
  76. 76. SpiroSmart
  77. 77. SpiroSmart
  78. 78. within ~5-7% of a real spirometer phone app doctor visit
  79. 79. appropriate for trending and screening
  80. 80. global health non-profit
  81. 81. global health non-profit patient and doctors
  82. 82. global health non-profit patient and doctors pharmaceutical drug trials
  83. 83. currently undergoing FDA 510k device approval diagnostic deployment in India started in January
  84. 84. other applications in health? mhealth and newborns?
  85. 85. neonatal jaundice in the US kernicterus: 21 hazardous jaundice: 1158 extreme jaundice: 2,317 severe jaundice: 35,000 phototherapy: 290,000 visible jaundice: 3.5 million births/year: 4.1 million
  86. 86. Method Accuracy Disadvantages TSB Gold standard (r=1.0) Painful, costly, inconvenient, delayed Accurate (r= 0.75 -0.93) Meter = $7000 tips $5 unavailable in most physician offices TcB Visual assessment (provider or parent) not accurate (r= 0.36 - 0.7), underestimates severity No standardization lighting, pigmentation
  87. 87. bilirubin level in blood blood draw jaundice level
  88. 88. bilirubin level in blood blood draw yellowness camera jaundice level
  89. 89. bilirubin level in blood blood draw estimated jaundice level yellowness camera processing
  90. 90. bilicam
  91. 91. bilicam correlates with TSB at 0.84 TcB correlates anywhere from 0.71 to 0.9
  92. 92. mobile apps are poised to take over the market nokia x-challenge: grand prize: mobile device that monitors vitals signs can diagnose 10 of 15 diseases
  93. 93. the future of mHealth?
  94. 94. the future of mHealth? • new sensors will be integrated into phones
  95. 95. the future of mHealth? • new sensors will be integrated into phones • health sensing and mobile phone manufacturing will become highly intertwined
  96. 96. the future of mHealth? • new sensors will be integrated into phones • health sensing and mobile phone manufacturing will become highly intertwined • FDA will have a big say in how quickly phones can be built and pushed out, and what apps are “OK”
  97. 97. the future of mHealth? • new sensors will be integrated into phones • health sensing and mobile phone manufacturing will become highly intertwined • FDA will have a big say in how quickly phones can be built and pushed out, and what apps are “OK”
  98. 98. the future of mHealth? • new sensors will be integrated into phones • health sensing and mobile phone manufacturing will become highly intertwined • FDA will have a big say in how quickly phones can be built and pushed out, and what apps are “OK” • FDA sanctioned validity study
  99. 99. the future of mHealth? • new sensors will be integrated into phones • health sensing and mobile phone manufacturing will become highly intertwined • FDA will have a big say in how quickly phones can be built and pushed out, and what apps are “OK” • FDA sanctioned validity study • four melanoma apps
  100. 100. the future of mHealth? • new sensors will be integrated into phones • health sensing and mobile phone manufacturing will become highly intertwined • FDA will have a big say in how quickly phones can be built and pushed out, and what apps are “OK” • FDA sanctioned validity study • four melanoma apps • 30% of cancerous moles classified as benign
  101. 101. what app makes a phone a medical device?
  102. 102. what app makes a phone a medical device? apps that transform a phone or connect to a medical sensor
  103. 103. what app makes a phone a medical device? apps that transform a phone or connect to a medical sensor apps that control a device through a phone
  104. 104. what app makes a phone a medical device? apps that transform a phone or connect to a medical sensor apps that control a device through a phone apps that display, transfer, store, medical device data
  105. 105. what app makes a phone a medical device? apps that transform a phone or connect to a medical sensor apps that control a device through a phone apps that display, transfer, store, medical device data apps that interact with electronic health records or simple health data
  106. 106. m ay be ye s ye s ye s what app makes a phone a medical device? apps that transform a phone or connect to a medical sensor apps that control a device through a phone apps that display, transfer, store, medical device data apps that interact with electronic health records or simple health data
  107. 107. m ay be ye s ye s ye s what app makes a phone a medical device? apps that transform a phone or connect to a medical sensor apps that control a device through a phone apps that display, transfer, store, medical device data apps that interact with electronic health records or simple health data psychiatry, medical dosing, symptom logs, general fitness apps…
  108. 108. m ay be m ay be ye s ye s ye s what app makes a phone a medical device? apps that transform a phone or connect to a medical sensor apps that control a device through a phone apps that display, transfer, store, medical device data apps that interact with electronic health records or simple health data psychiatry, medical dosing, symptom logs, general fitness apps…
  109. 109. what app makes a phone a medical device? we will see?
  110. 110. some approved apps
  111. 111. some approved apps
  112. 112. some approved apps
  113. 113. some approved apps
  114. 114. some approved apps
  115. 115. my take
  116. 116. eclarson.com eclarson@lyle.smu.edu > slide to unlock @ec_larson Thank You!
  117. 117. big data, small data: the future of sensing in health and sustainability eclarson.com eclarson@lyle.smu.edu > slide to unlock @ec_larson collaborators: ! Joseph Camp Shwetak Patel Jim Stout, MD Jim Taylor, MD Margaret Rosenfeld, MD Gaetano Boriello Mayank Goel Lilian DeGreef Thank You! eric c. larson | eclarson.com Assistant Professor Computer Science and Engineering
  118. 118. big data, small data: the future of sensing in health and sustainability eclarson.com eclarson@lyle.smu.edu @ec_larson collaborators: ! Joseph Camp Shwetak Patel Jim Stout, MD Jim Taylor, MD Margaret Rosenfeld, MD Gaetano Boriello Mayank Goel Lilian DeGreef Thank You! eric c. larson | eclarson.com Assistant Professor Computer Science and Engineering

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