2. DECONVOLUTION ANALYSIS OF
RENOGRAPHIC CURVES AND
TRANSIT TIME ASSESSMENT
Dr V Sivasubramaniyan
Dept. of Nuclear Medicine
SSSIHMS
*
Dr G Venkataraman
Mr Hari Nanda Kumar
SSSIHL
*
3. AIMS
• REPORT INDIGENOUS SOFTWARE
• CREATED BY OUR OWN STUDENTS
• Renal Parenchymal Transit Time Analysis
• UTILITY & CLINICAL SIGNIFICANCE
4. DECONVOLUTION ANALYSIS
OF RENOGRAM.
•Kenny et al – BMJ 1975.
•Diffey et al – JNM 1976.
•Piepsy et al – BJR 1982.
•Lupton et al – NMC 1984
•Britton et al – BJU 1987.
5. CONVOLUTION & DECONVOLUTION
• f (x) = A* exp (-a1*x) + B* exp (-a2*x)
• g (x) = 500./1 + exp {(x-xg) / x01}
Convolution = Viewing ‘g(x)’ via the lens
‘f(x)’ or vice versa.
Deconvolution = Deriving ‘g(x)’ from
known ‘h(x)’ and ‘f(x)’.
6. METHODOLOGY
Platform : MATLAB Ver 5.0
• Simulation studies.
• Deconvolution with discrete data
sets.
• Randomness checking.
• Smoothing procedures.
• Check out analysis from literature.
7.
8.
9.
10.
11.
12. ANALYTICAL STEPS
• Greaderauto
• Enter the file name of the curve
• H: 55470_k2 20021209 savescreen.2.jpg
• Enter the name of the patient
• Anushree sahoo
13.
14.
15.
16.
17.
18.
19.
20.
21.
22.
23.
24.
25.
26.
27.
28.
29. RESULTS
• OBSTRUCTIVE 70 8 to 15 min
• NON-OBSTRUCTIVE 60 1.8 to 2.8 min
• TOTAL CASES 130
