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FGAI4H-R-040-A08
Cambridge, 21-24 March 2023
Source: LMU Munich
Title: Att.8 – Presentation - AI based software for dentistry - a brief market overview
Contact: Janet Brinz E-mail: janet.brinz@med.uni-muenchen.de
Abstract: This PPT contains a presentation on AI based software for dentistry - a brief market
overview, given in the AI for Dentistry Symposium on 21 March 2023.
AI in dentistry
A brief market overview
21st of March 2023 | Dr Janet Brinz
Department of Conservative Dentistry and Periodontology,
University Hospital, LMU Munich
AI in healthcare market
AI in dentistry – a brief market overview | Department of Conservative Dentistry and Periodontology,University Hospital, LMU Munich | Dr Janet Brinz 3
Forecast
Rapid growth and development of the market
->increase in the number of players and products
[1]
[1]
[2]
[3]
Introduction to the
4
AI in Dentistry market
North America:
•Overjet (USA)
•Diagnocat (USA)
•Pearl (USA)
•Videa (USA)
•Adravision (USA)
•Velmeni (USA)
•Dentistry.ai (USA)
•Denti.ai (Canada)
•TSV tooth secret view (Canada)
Europe:
•AssistDent by Manchester Imaging Limited (United Kingdom)
•Allisone (France)
•Cellmatiq (Germany)
•Dentalxrai (Germany)
•Densilia (Germany)
•Dentomo (Spain)
•Promaton (Netherlands)
•vistaSoft by Dürr Dental (Germany)
Asia:
•Orca, Ceph X (Israel)
•Ivory.ai (India)
•Deep care (China)
Australia:
• Eyes of AI (Australia)
These are just the companies focusing on X-Ray diagnostics!
AI in dentistry – a brief market overview | Department of Conservative Dentistry and Periodontology,University Hospital, LMU Munich | Dr Janet Brinz
[4]
Segments of AI in dentistry
5
X-ray analysis
Intraoral films, panoramic –
Conservative dentistry, periodontology, endodontics
Cephalometric analysis -
Orthodontics
CBCT –
Oral surgery + orthodontics
AI in dentistry – a brief market overview | Department of Conservative Dentistry and Periodontology,University Hospital, LMU Munich | Dr Janet Brinz
[5] [6]
[7]
[8]
Segments of AI in dentistry
6
Esthetic dentistry
AI generated cosmetic
smile simulation
Smile analysis and treatment
simulation
AI generated Wax up
AI in dentistry – a brief market overview | Department of Conservative Dentistry and Periodontology,University Hospital, LMU Munich | Dr Janet Brinz
[9]
[10]
[11]
Segments of AI in dentistry
7
Other applications
CBCT analysis for
aligner treatment
Low dose CBCT Scan with AI
enhanced Image Quality
Reduction of metal artifacts
Analysis of call data (speech) and
AI Analytics
Chat on website to answer FAQs,
schedule appointments
AI assisted practice/ patient management
AI in dentistry – a brief market overview | Department of Conservative Dentistry and Periodontology,University Hospital, LMU Munich | Dr Janet Brinz
[12]
[12]
[13]
[14]
[15]
Capabilities of
▪ How do dentists benefit from this software?: decrease workload, increase accuracy, enhance patient
experience
▪ What most can do: Segmentation, Caries detection, Detetction of dental restorations/ treatments (Root
canal, Filling, Crown, Bridge, Implant), Calculus detection, Periapical radiolucency detection, treatment plan
suggestions
▪ Where do they differ? Pricing, Performance/ accuracy (different datasets, different algorithms), integration
with other systems (e.g. CBCT), user interface, medical/ FDA clearances
8
AI in dentistry
Company Product Status
adravision
5Handed ISO 13485 certification,
undergoing regulatory clearance
in a few countries
Velmeni
Second Dentist currently under FDA approval
review
Manchester Imaging Limited AssistDent UKCE marked medical device,
pursuing EU MDR
CellmatiQ DentaliQ ortho EU / CE certified MDD class 1
medical device
dentalXrai dentalXrai Pro 3.0 certified as a medical device
Company Product Status
Overjet, Inc.
Overjet Dental Assist,
Overjet Caries Assist,
Overjet Calculus Assist FDA cleared (510 (k))
Pearl Inc. Second Opinion FDA cleared (510 (k))
VideaHealth, Inc
Videa Caries Assist,
Videa Perio Assist FDA cleared (510 (k))
3D Smile USA, Inc 3D Predict FDA cleared (510 (k))
HDX WILL Corp. eco-x Series FDA cleared (510 (k))
Denti.AI Technology Inc. Denti.AI Auto-Chart FDA cleared (510 (k))
AI in dentistry – a brief market overview | Department of Conservative Dentistry and Periodontology,University Hospital, LMU Munich | Dr Janet Brinz
Regulation of medical devices
9
FDA Regulatory Framework
Locked Algorithm Adaptive Algorithm
Definition
Always produces the same result unless
updated by the developer
Can update itself based on new data
ML Algorithm Static Continuous Learning
Advantages Less risky, predictable results
Can potentially become more accurate
over time
Challenges
May become less accurate as real-world
data differs from training data
May infer patterns from biased practices
or underperform in small subgroups of
patients
▪ AI based Software (e.g. caries detection) classifies as Software as Medical Device (SaMD)
▪ Medical devices are classified into different categories based on their risk level – Class II – medium risk
▪ Medical devices need to be evaluated by authorities (such as FDA) before they can be placed on the
market to ensure safety and efficacy
▪ As of now only locked algorithms have been approved
▪ Adaptive algorithms not yet approved by the FDA, as current regulatory pathways do not allow for approval of
a device that constantly improves itself
▪ FDA is working on developing a framework for regulating adaptive algorithms
AI in dentistry – a brief market overview | Department of Conservative Dentistry and Periodontology,University Hospital, LMU Munich | Dr Janet Brinz
Future Trajectory
• Trajectory and future of AI in dentistry companies dependent on: market demand, technological innovation,
regulatory environment, ethical issues, and social acceptance
▪ Opportunities:
1.Growing demand for AI-powered dental solutions
2.Increase in investment and research in the field of AI in dentistry
3.Expansion of AI-powered products in various segments of dentistry
4.Development of more advanced AI algorithms and technologies
▪ Challenges:
1.Regulation and approval processes for AI-powered dental solutions can be lengthy and complicated
2.High initial investment for implementing AI technology in dental practices
3.Concerns about data privacy and security of patient information
4.Need for continuous improvement and updates in technology to keep up with advancing competition
10
Opportunities and Challenges
AI in dentistry – a brief market overview | Department of Conservative Dentistry and Periodontology,University Hospital, LMU Munich | Dr Janet Brinz
Conclusion
• AI in dentistry is a rapidly growing field with numerous opportunities and challenges
• There are many players offering a variety of products and services in the current market, which require
regulation
• It is important to monitor and research the market to understand the opportunities and challenges in the
industry
• Overcoming challenges may require collaboration between researchers, developers, regulators and
professionals
11
AI in Dentistry market
AI generated image:
Dental practices of the future?
DALL-E prompt:
futuristic AI assisted high tech dental practice
AI in dentistry – a brief market overview | Department of Conservative Dentistry and Periodontology,University Hospital, LMU Munich | Dr Janet Brinz
[16]
Thank you
Correspondence
Dr Janet Brinz
Department of Conservative Dentistry and Periodontology
University Hospital, LMU Munich
E-Mail: janet.brinz@med.uni-muenchen.de
For your attention
Sources
▪ [1] https://www.grandviewresearch.com/industry-
analysis/artificial-intelligence-ai-healthcare-market
▪ [2] https://www.statista.com/statistics/1334826/ai-in-healthcare-
market-size-worldwide/
▪ [3] https://www.alliedmarketresearch.com/artificial-intelligence-in-
healthcare-market
▪ [4] https://commons.wikimedia.org/wiki/File:Worldmap_vector.svg
▪ [5] https://www.dentalxr.ai/en/technology/
▪ [6] https://manchester-imaging.com/
▪ [7] https://cellmatiq.com
▪ [8] https://diagnocat.de/
▪ [9] https://preteeth.com/AIautoWaxup,
[10]https://preteeth.com/preteethAIpro
▪ [11] https://dentrino.ai/
▪ [12]
http://www.hdxwill.com/en/bbs/board.php?bo_table=sub0201
13
▪ [13] https://3dpredict.com/
▪ [14] https://www.peerlogic.com/solutions/dental-practice-owners/
▪ [15] http://www.dentalattendant.com/
▪ https://www.pewtrusts.org/en/research-and-analysis/issue-
briefs/2021/08/how-fda-regulates-artificial-intelligence-in-medical-
products
▪ https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfpmn/pmn.cf
m
▪ https://www.medtechintelligence.com/feature_article/the-
regulatory-aspects-of-ai-ml-based-samd/
▪ https://3dpredict.com/3d-predict-receives-fda-clearance-for-ai-
based-innovative-aligners/
▪ https://www.fda.gov/medical-devices/software-medical-device-
samd/artificial-intelligence-and-machine-learning-aiml-enabled-
medical-devices?
▪ [16] https://labs.openai.com/
AI in dentistry – a brief market overview | Department of Conservative Dentistry and Periodontology,University Hospital, LMU Munich | Dr Janet Brinz

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FGAI4H-R-040-A08.pptx

  • 1. FGAI4H-R-040-A08 Cambridge, 21-24 March 2023 Source: LMU Munich Title: Att.8 – Presentation - AI based software for dentistry - a brief market overview Contact: Janet Brinz E-mail: janet.brinz@med.uni-muenchen.de Abstract: This PPT contains a presentation on AI based software for dentistry - a brief market overview, given in the AI for Dentistry Symposium on 21 March 2023.
  • 2. AI in dentistry A brief market overview 21st of March 2023 | Dr Janet Brinz Department of Conservative Dentistry and Periodontology, University Hospital, LMU Munich
  • 3. AI in healthcare market AI in dentistry – a brief market overview | Department of Conservative Dentistry and Periodontology,University Hospital, LMU Munich | Dr Janet Brinz 3 Forecast Rapid growth and development of the market ->increase in the number of players and products [1] [1] [2] [3]
  • 4. Introduction to the 4 AI in Dentistry market North America: •Overjet (USA) •Diagnocat (USA) •Pearl (USA) •Videa (USA) •Adravision (USA) •Velmeni (USA) •Dentistry.ai (USA) •Denti.ai (Canada) •TSV tooth secret view (Canada) Europe: •AssistDent by Manchester Imaging Limited (United Kingdom) •Allisone (France) •Cellmatiq (Germany) •Dentalxrai (Germany) •Densilia (Germany) •Dentomo (Spain) •Promaton (Netherlands) •vistaSoft by Dürr Dental (Germany) Asia: •Orca, Ceph X (Israel) •Ivory.ai (India) •Deep care (China) Australia: • Eyes of AI (Australia) These are just the companies focusing on X-Ray diagnostics! AI in dentistry – a brief market overview | Department of Conservative Dentistry and Periodontology,University Hospital, LMU Munich | Dr Janet Brinz [4]
  • 5. Segments of AI in dentistry 5 X-ray analysis Intraoral films, panoramic – Conservative dentistry, periodontology, endodontics Cephalometric analysis - Orthodontics CBCT – Oral surgery + orthodontics AI in dentistry – a brief market overview | Department of Conservative Dentistry and Periodontology,University Hospital, LMU Munich | Dr Janet Brinz [5] [6] [7] [8]
  • 6. Segments of AI in dentistry 6 Esthetic dentistry AI generated cosmetic smile simulation Smile analysis and treatment simulation AI generated Wax up AI in dentistry – a brief market overview | Department of Conservative Dentistry and Periodontology,University Hospital, LMU Munich | Dr Janet Brinz [9] [10] [11]
  • 7. Segments of AI in dentistry 7 Other applications CBCT analysis for aligner treatment Low dose CBCT Scan with AI enhanced Image Quality Reduction of metal artifacts Analysis of call data (speech) and AI Analytics Chat on website to answer FAQs, schedule appointments AI assisted practice/ patient management AI in dentistry – a brief market overview | Department of Conservative Dentistry and Periodontology,University Hospital, LMU Munich | Dr Janet Brinz [12] [12] [13] [14] [15]
  • 8. Capabilities of ▪ How do dentists benefit from this software?: decrease workload, increase accuracy, enhance patient experience ▪ What most can do: Segmentation, Caries detection, Detetction of dental restorations/ treatments (Root canal, Filling, Crown, Bridge, Implant), Calculus detection, Periapical radiolucency detection, treatment plan suggestions ▪ Where do they differ? Pricing, Performance/ accuracy (different datasets, different algorithms), integration with other systems (e.g. CBCT), user interface, medical/ FDA clearances 8 AI in dentistry Company Product Status adravision 5Handed ISO 13485 certification, undergoing regulatory clearance in a few countries Velmeni Second Dentist currently under FDA approval review Manchester Imaging Limited AssistDent UKCE marked medical device, pursuing EU MDR CellmatiQ DentaliQ ortho EU / CE certified MDD class 1 medical device dentalXrai dentalXrai Pro 3.0 certified as a medical device Company Product Status Overjet, Inc. Overjet Dental Assist, Overjet Caries Assist, Overjet Calculus Assist FDA cleared (510 (k)) Pearl Inc. Second Opinion FDA cleared (510 (k)) VideaHealth, Inc Videa Caries Assist, Videa Perio Assist FDA cleared (510 (k)) 3D Smile USA, Inc 3D Predict FDA cleared (510 (k)) HDX WILL Corp. eco-x Series FDA cleared (510 (k)) Denti.AI Technology Inc. Denti.AI Auto-Chart FDA cleared (510 (k)) AI in dentistry – a brief market overview | Department of Conservative Dentistry and Periodontology,University Hospital, LMU Munich | Dr Janet Brinz
  • 9. Regulation of medical devices 9 FDA Regulatory Framework Locked Algorithm Adaptive Algorithm Definition Always produces the same result unless updated by the developer Can update itself based on new data ML Algorithm Static Continuous Learning Advantages Less risky, predictable results Can potentially become more accurate over time Challenges May become less accurate as real-world data differs from training data May infer patterns from biased practices or underperform in small subgroups of patients ▪ AI based Software (e.g. caries detection) classifies as Software as Medical Device (SaMD) ▪ Medical devices are classified into different categories based on their risk level – Class II – medium risk ▪ Medical devices need to be evaluated by authorities (such as FDA) before they can be placed on the market to ensure safety and efficacy ▪ As of now only locked algorithms have been approved ▪ Adaptive algorithms not yet approved by the FDA, as current regulatory pathways do not allow for approval of a device that constantly improves itself ▪ FDA is working on developing a framework for regulating adaptive algorithms AI in dentistry – a brief market overview | Department of Conservative Dentistry and Periodontology,University Hospital, LMU Munich | Dr Janet Brinz
  • 10. Future Trajectory • Trajectory and future of AI in dentistry companies dependent on: market demand, technological innovation, regulatory environment, ethical issues, and social acceptance ▪ Opportunities: 1.Growing demand for AI-powered dental solutions 2.Increase in investment and research in the field of AI in dentistry 3.Expansion of AI-powered products in various segments of dentistry 4.Development of more advanced AI algorithms and technologies ▪ Challenges: 1.Regulation and approval processes for AI-powered dental solutions can be lengthy and complicated 2.High initial investment for implementing AI technology in dental practices 3.Concerns about data privacy and security of patient information 4.Need for continuous improvement and updates in technology to keep up with advancing competition 10 Opportunities and Challenges AI in dentistry – a brief market overview | Department of Conservative Dentistry and Periodontology,University Hospital, LMU Munich | Dr Janet Brinz
  • 11. Conclusion • AI in dentistry is a rapidly growing field with numerous opportunities and challenges • There are many players offering a variety of products and services in the current market, which require regulation • It is important to monitor and research the market to understand the opportunities and challenges in the industry • Overcoming challenges may require collaboration between researchers, developers, regulators and professionals 11 AI in Dentistry market AI generated image: Dental practices of the future? DALL-E prompt: futuristic AI assisted high tech dental practice AI in dentistry – a brief market overview | Department of Conservative Dentistry and Periodontology,University Hospital, LMU Munich | Dr Janet Brinz [16]
  • 12. Thank you Correspondence Dr Janet Brinz Department of Conservative Dentistry and Periodontology University Hospital, LMU Munich E-Mail: janet.brinz@med.uni-muenchen.de For your attention
  • 13. Sources ▪ [1] https://www.grandviewresearch.com/industry- analysis/artificial-intelligence-ai-healthcare-market ▪ [2] https://www.statista.com/statistics/1334826/ai-in-healthcare- market-size-worldwide/ ▪ [3] https://www.alliedmarketresearch.com/artificial-intelligence-in- healthcare-market ▪ [4] https://commons.wikimedia.org/wiki/File:Worldmap_vector.svg ▪ [5] https://www.dentalxr.ai/en/technology/ ▪ [6] https://manchester-imaging.com/ ▪ [7] https://cellmatiq.com ▪ [8] https://diagnocat.de/ ▪ [9] https://preteeth.com/AIautoWaxup, [10]https://preteeth.com/preteethAIpro ▪ [11] https://dentrino.ai/ ▪ [12] http://www.hdxwill.com/en/bbs/board.php?bo_table=sub0201 13 ▪ [13] https://3dpredict.com/ ▪ [14] https://www.peerlogic.com/solutions/dental-practice-owners/ ▪ [15] http://www.dentalattendant.com/ ▪ https://www.pewtrusts.org/en/research-and-analysis/issue- briefs/2021/08/how-fda-regulates-artificial-intelligence-in-medical- products ▪ https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfpmn/pmn.cf m ▪ https://www.medtechintelligence.com/feature_article/the- regulatory-aspects-of-ai-ml-based-samd/ ▪ https://3dpredict.com/3d-predict-receives-fda-clearance-for-ai- based-innovative-aligners/ ▪ https://www.fda.gov/medical-devices/software-medical-device- samd/artificial-intelligence-and-machine-learning-aiml-enabled- medical-devices? ▪ [16] https://labs.openai.com/ AI in dentistry – a brief market overview | Department of Conservative Dentistry and Periodontology,University Hospital, LMU Munich | Dr Janet Brinz