1. Barnard Institute of Radiology & Oncology , Madras Medical College & Government General Hospital, and Advanced Nuclear Medicine Research Institute , Chennai. E. Mail – dreprabhu@gmail.com Medical Imaging in Future – Physician’s Perspectives Dr. E. Prabhu, M.D.(Gen. Medicine), D.R.M., FIMSA Nuclear Medicine Physician, E.C. member, SNM (India) & NABH Assessor for Medical Imaging 15 th August, 2010
2. Internal Medicine has always attracted the best students, has prestige, poses intellectual challenge and promises full patient care. Challenges faced by the Current Physician There fore we need periodic up-dates in Technical advances in genetics and molecular biology Medical Imaging, Computers and their role in Clinical Decision Making Political, Economic & Life- style challenges in modern society
3. Currently, we do not focus only on the causes of our patient’s problems. Instead, we search for modifiable molecular manifestations of the problems in terms of location, structure, function & biochemistry. Principles of Current Medical Imaging
4. K Shell L Shell M Shell DNA Strand Options in Medical Imaging includes the Digital Radiography, Ultrasound, the Computed Tomography, Optical Imaging, Magnetic Resonance & Functional MR, the SPECT / PET and the PACS for Image Archiving and Communication
5. Clerca. J et al; Scintigraphic Imaging of Paediatric Thyroid Dysfunction, Horm Res (2008);70:1-13 There are about 20,000 different types of molecules in the body. Either these molecules send wrong messages are don’t receive right messages. Recognition of the molecules is the basic for diseases. … functions are fast processes of short duration, while structures are slow processes of long duration …
6. Technological Advances in Medicine for Diagnosis and Treatment are Less Invasive, Precise and Objective Modern Medical Imaging helps in Integration and Weighing of Complex Clinical information This helps us to take Leadership position in Medicine by interpreting bewildering array of information and making wise Clinical decisions
9. Spinal Metastasis & Metastatic Disease to the Spine & Related Structures Approximately 94-98% of these patients present with epidural and/or vertebral involvement. Intradural extramedullary and intramedullary seeding of systemic cancer is unusual; they account for 5-6% and 0.5-1% of spinal metastases, respectively. Patil et al. National inpatient complications and outcomes after surgery for spinal metastasis from 1993-2002. Cancer. Aug 1 2007;110(3):625-30.
22. Then Dawn of Fusion & Multidisciplinary Medical Imaging ...and borrowing ideas from Radioastronomy..
23. PET MRI CT PET-MRI PET-CT PET-CT-MRI Receptors, enzymes, membrane transporters and Signal transduction proteins in renal diseases, Tissue Hypoxia and Apoptosis in renovascular disease and in obstruction Endothelial dysfunction and assessment of molecular response to drugs and atherosclerosis; Drug delivery systems based on anion, cation, glucose and peptide transporters Reporter gene therapy and monitoring rejection, Targeting receptors, oncoproteins, growth factors and cytokines Anatomical and Functional Renal Images PET+CT+MRI
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25. Current trends in Molecular Imaging 131 I Whole Body Scan 124 I Whole Body PET Scan 18 F - FDG Whole Body PET Scan
33. 'The wisdom of the Prudent is to Understand His way...' Current Research in Medicine and Medical Imaging
34. ‘ ....in future, diagnoses will be molecular, treatment will be molecular, and monitoring the response to treatment will be molecular...’ . 1970 2010 Thank You Personalized Medicine
