1. Micro Medical and Pharmaceutical Devices
Presented by:
Donna Bibber

2. ABOUT MES
µ 8 Micro Experienced Project Engineers
µ Multiple MICRO material and processing platforms
µ 24+ Yrs Micro Mfg/High Speed Assembly
µ 1,000+ Successful Micro Programs
MES SERVICES
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3. Product Development
eurosurgical coil assemblies ransdermal patches
harmaceutical Infused implants ntraocular Implants
ydrogel orthopedic implants icro Needle Arrays
ollagen-induced Cardio Implants nsulin delivery pump assembly
.0 cu mm Silicone valves mplantable Batteries
icrofluidic chips ioResorbable Polymer Implants

4. Micro Assembly Challenges
ltra Precision Positioning
arting line/draft alignment
urface finish
ptical finish and vision

5. Microfluidic Tooling
nd Mills as small as 0.0001”
(3 um)
jector pins as small as .004”
(100 um)
avities as small as 0.007”
ore pins .0029”
ates 0.002”
all thicknesses 0.0015”

6. Catheter Assembly
µ 50 um Lumen
tip edge
µ 0.5mm lumen
OD
µ Multiple core
pins to
accommodate
.0002” range
Lumen sizes

7. Scaffold Assembly
•PLA Scaffold
•0.050” posts
•0.003” weld bead

8. PLA Staple Assembly
µ Snap Fit Design
µ Multiple Cavity
µ Fully Automatic Loading
µ Custom end of arm tooling
µ Multi-axis robotic loading

9. Filled and Sealed
Surgical Marker
µ Spin Welding
µ PEEK Vessel
µ Vacuum Nesting
µ Automatic Fill and
Seal System (syringe)

10. Micro Features

11. PLA Anchor
µ 0.0008” tip radius
µ OAL 0.085”
µ Side Hole 0.010”
µ Using Runner/Sprue as assembly a

12. Endoscopy
Assembly µ Multiple
machined
components
µ Tolerance
stack-up
study
µ Scale-up to
MIM

13. Drug Well
Assembly
µ Membrane attachment
µ Designed-in alignment features
µ 50 um lumens

14. Transdermal
Needle Array

15. Glaucoma Drain
Suture Assembly
µ 0.010”
orifice
µ Parting
line
critical
µ 0.015”
Side
action
suture
holes
µ Radial
wedge
shape
action

16. Intraocular Lens
Assembly
atched arc lengths

17. Intraocular
Vacuum
Assembly
ritical Parting line directly sitting on cornea

18. Silicone Micro
Structures
µ 84 Million discrete shapes on
each chip
µ 100 um Tall, 100 um Wide
Shapes
µ 3 um Diameter, 3 um Depth
Posts on top
µ Material- Bio-Compatible
Silicone
µ Assembly Aid=Repeatable
and Quantifiable Surface
(tissue grasping and
adhesive surface)

19. Gastric
Bypass
Assembly

20. Neurosurgical
Assembly
µ 0.001” wall
thickness
µ 0.014” OAL
µ Vacuum
assist vs.
Tweezers

21. Micro Inspection Capabilities
aser Scanning Vision Systems
FM
ideo CMM
ouch Probe Systems w/ 3 micron diameter
probes
rofilometer
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22. Micro Assembly Methods
voidance- Geometry Combining
elective Sacrificial Material Melting (silicone, PET)
nsert or 2-shot Micro Molding
elding
µ Laser
µ Ultrasonic

23. Micro Device Assembly
Molding
µ MM
µ LIM
µ MIM
µ CIM
Stamping
Machined

24. Micro Assembly
System
nd. Vac. Nests
sec cycle
eat seal
ltrasonic welding
nline Psi decay test

25. Injection Molding Simulations,
Modeling, Analysis

26. Micro Mold Flow Analysis Technology
roprietary Meshing Technique for Micro Parts
haracterized and Analyze Resorbs, PC Lenses, Silicone
nsurance Policy for First Shot Quality
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27. Mesh Thickness

28. Deflection-All Effects

29. Conclusion
eveloping medical and pharmaceutical micro assemblies requires
successful integration of many ultra- precision processes/materials
urface finish, feature size and positioning, and extreme critical
care environment results in successful micro assemblies
f your micro partner has gone beyond the feature size and
tolerance stack-up requirements, you are much less likely to be a
science experiment

30. Thank you.
We look forward to working with you.
Micro Engineering Solutions
www.wickedsmall.com