The role of melatonin in pediatric headaches

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Evidence Based Medicine Series: The role of melatonin in pediatric headaches Sarah Lallaman 3 rd Year Pediatric Resident

Patient Presentation ,[object Object],[object Object],[object Object],[object Object]

Patient management ,[object Object],[object Object],[object Object],[object Object]

Patient Follow-up ,[object Object],[object Object],[object Object],[object Object],[object Object]

Background Information: The pineal gland ,[object Object],[object Object]

Background Information: Melatonin ,[object Object],[object Object],[object Object]

Background Information: Melatonin ,[object Object],[object Object]

Properties of melatonin ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Clinical Question: ,[object Object],[object Object],[object Object],[object Object],[object Object]

Literature Search: Pub Med ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Other literature searches ,[object Object],[object Object],[object Object],[object Object]

Selected Article ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Reviewing the article: The Patients ,[object Object],[object Object],[object Object],[object Object],[object Object]

Reviewing the article: The Headaches ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Reviewing the article: Exclusions for the study ,[object Object],[object Object],[object Object],[object Object],[object Object]

Reviewing the article: The study design ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Reviewing the article: The data ,[object Object],[object Object],[object Object],[object Object]

Reviewing the article: The data Mean (SD) P<0.001 9.7 (14.5) 9.9 (14.4) 10.4 (14.3) 13.5 (15.9) Duration of attacks (h) P<0.001 5.7 (6.7) 6.9 (7.1) 8.7 (7.5) 12.3 (8.9) Frequency of attacks / month Friedman test 3 month follow-up 2 month follow-up 1 month follow-up Baseline

Reviewing the article: The nitty-gritty about the stats ,[object Object],[object Object]

Reviewing the article: The weaknesses of the stats ,[object Object],[object Object],[object Object]

Reviewing the article: Is this evidence valid? ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Reviewing the article: The weaknesses ,[object Object],[object Object],[object Object],[object Object]

Reviewing the article: Is this information important? ,[object Object],[object Object]

Application of the evidence: Risks for the therapy ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Applying the evidence: Availability, cost and ease ,[object Object],[object Object],[object Object],[object Object]

How this applies to my patient ,[object Object],[object Object],[object Object]

Knowing what I know now... ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Where to go from here? ,[object Object],[object Object],[object Object],[object Object]

References ,[object Object],[object Object],[object Object],[object Object]

Acknowledgements ,[object Object],[object Object],[object Object]

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