On August 18, 2003, Fritzgerald presented to the emergency room of RHD Memorial Medical Center in Dallas, Texas, complaining of abdominal pain, lack of appetite, nausea, vomiting, a history of reflux, and a history of a 30-pound weight loss. The admitting physician consulted with Dr. Richard Holmes, a general surgeon, who determined that Fritzgerald had a duodenal ulcer and needed surgery. Holmes discharged Fritzgerald pending further testing and, 11 days later on August 29, Holmes performed surgery. Fritzgerald tolerated the procedure well. Holmes started Fritzgerald on an antibiotic to prevent a post-surgical abdominal infection and said he expected Fritzgerald to remain in the hospital for about three to five days. Fritzgerald appeared to be recovering until September 1. Early that morning, Fritzgerald developed a high fever and his blood pressure began to drop. The nursing staff called Holmes about Fritzgerald's condition, and Holmes ordered tests. Fritzgerald exhibited symptoms of systemic inflammatory response syndrome, or sepsis. In other words, an infection was attacking his entire body. By late evening of September 1, Fritzgerald's condition had deteriorated to septic shock, meaning his organs were not getting adequately profused, and Fritzgerald was in a life-threatening condition. The hospitalist coordinating Fritzgerald's care consulted Prabhakar, an infectious disease doctor. Prabhakar first saw Fritzgerald around 10 p.m. on September 1. After reviewing all available data and examining the patient, Prabhakar believed Fritzgerald had peritonitis, which is an intra-abdominal infection. Mr.Prabhakar believe the infection could be related to the surgery, but the source of the infection was yet undetermined. Based on his clinical assessment of Fritzgerald's condition, Mr.Prabhakar ordered empiric antibiotic therapy-a broad spectrum antibiotic-to treat the most common pathogens that could cause the infection. The antibiotic therapy Prabhakar prescribed did not treat hospital-acquired Methicillin-Resistant Staphylococcus Aureus (MRSA). The antibiotic was started on the evening of September 1. Other specialist physician also consulted on Fritzgerald's case, including a pulmonary critical care physician. They ordered numerous tests and chest x-rays, but none was able to determine the source of Fritzgerald's infection. Meanwhile, Fritzgerald's organs began to fail and his body diverted blood flow away from his extremities and to his vital organs through a process called vascular redistribution phenomenon. He was given a drug called Xigris to counteract this phenomenon and was transferred to the intensive care unit.