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Aldactone 25 mg
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(Spironolactone)
Uses
Spironolactone is used in the treatment of hyperaldosteronism (the body produces too much aldosterone, a
naturally occurring hormone); low potassium levels; heart failure; and in pa ents with edema (fluid reten on)
caused by various condi ons, including liver, or kidney disease. It is also used alone or with other medica ons
to treat high blood pressure.
How it works
Spironolactone belongs to a class of medica ons called aldosterone receptor antagonists. It causes the
kidneys to eliminate unneeded water and sodium from the body into the urine, but reduces the loss of
potassium from the body.
Common side effects
gastrointes nal disturbances, toxic epidermal necrolysis, itching of skin, breast pain, nausea, loss of hair,
changes in libido, liver problems, pale red raised itchy skin, leg cramps, increased potassium level, abnormal
blood counts, Abnormally large breasts in male, electrolyte disturbances, acute renal failure., confusion,
feeling sick, dizziness, drug rash, serious widespread allergic reac on with rash involving skin and internal
lining of organ, breast tumours, menstrual disorders
ADDITIONAL INFORMATION REVIEWS (0)DESCRIPTION
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What is Spironolactone?
Spironolactone is a potassium-sparing diure c (water pill) that stops the body from absorbing too much salt
and keeps the potassium levels from decreasing greatly. It is prescribed for the treatment of hypertension
(high blood pressure) as well as to treat fluid reten on (edema) in people with conges ve heart failure,
cirrhosis of the liver, or a kidney disorder called nephri c syndrome. It is also used to treat or prevent
hypokalemia or low potassium levels in the blood.
Spironolactone is also prescribed for the diagnosis or treatment of a condi on in which there is too much
aldosterone in the body. Aldosterone is a hormone secreted by the adrenal glands that helps regulate the salt
and water balance in the body. Spironolactone is sold under various trade names, one of which is Aldactone
(made by RPG Life Sciences).
Important Informa on about Spironolactone
Do not take Spironolactone (Aldactone) if you have a known allergy to it, or if you have kidney disease, high
levels of potassium in your blood, or if you are unable to urinate. Do not take potassium supplements or other
diure cs while you are taking Spironolactone. Also avoid salt subs tutes or low sodium milk products that
contain potassium. These products can shoot up your potassium levels while taking this medicine
Prior to taking Spironolactone, let your doctor know if you have liver disease, or if you take st***dal
medicines or another diure c. Avoid a high salt diet while taking this medicine. High salt intake will cause your
body to retain water and can make this medicine less effec ve.
Do not exert more or become dehydrated while exercising and while in hot weather. Follow your doctor’s
direc ons about the type and amount of liquids you should drink. In some instances, consuming too much
liquid can be as harmful as not drinking enough. If you are being treated for high blood pressure, con nue
taking Spironolactone even if you don’t have any symptoms. High blood pressure doesn’t have any outwardly
signs. You may have to take this medicine for the rest of your life.
Spironolactone is an FDA pregnancy category C drug. It is known that this medicine can harm an unborn baby
if taken during pregnancy. Spironolactone can pass into breast milk and harm a nursing baby. Consult your
doctor before taking Spironolactone if any of these cases apply to you.
Before taking Spironolactone
Before taking Spironolactone (Aldactone), take care of all precau ons men oned above. Discuss them with
your doctor and clear all doubts which you may have about this drug.
How should I take Spironolactone?
Take Spironolactone strictly according to your doctor’s direc on or according to the instruc ons on the
medica on label. Do not alter the dosage unless your doctor advises you to do so. Also, do not take this
medica on a er the prescribed period is over. All medica ons come with a pa ent leaflet. Refer the
instruc ons in them for detailed informa on on that par cular medica on. Always store this medicine in a
cool and dry place.
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What if I miss a dose?
If you miss a dose of Spironolactone, take it as soon as you remember. Don’t take the missed dose if the me
to take the next dose is almost up. Taking mul ple doses near to each other can lead to excess medica on in
your body which can be harmful.
What if I overdose?
In case of an overdose of Spironolactone, get emergency medical a en on or call the Doctor Immediately.
Overdose may result in drowsiness, confusion, red skin rash, nausea, vomi ng, or diarrhea.
Things and Ac vi es to avoid while taking Spironolactone
Spironolactone may impact your thinking capability and reflexes. Take extra care while driving or other such
ac vi es that require a high level of mental awareness and alertness. Do not exert more or become
dehydrated while exercising and while in hot weather. Also, do not take potassium supplements or other
diure cs while you are taking Spironolactone. Also avoid salt subs tutes or low sodium milk products that
contain potassium. These products can shoot up your potassium levels while taking this medicine
Spironolactone Dosing Informa on
Spironolactone dosage may depend on a range of factors like age, s**, drug allergies, or seriousness of the
condi on among several other factors. Your dosage will be determined by your doctor a er examining you
properly. Remember to follow your doctor’s advice properly for best results.
Interac on for Aldactone
Food : It is be er to take this medicine with food.
Alcohol : Spironolactone and alcohol may have addi ve effects in lowering your blood pressure. You may
experience headache, dizziness, lightheadedness, fain ng, and/or changes in pulse or heart rate.
Pregnancy : It may be unsafe to use during pregnancy. Animal studies have shown adverse effects on the
foetus, however, there are limited human studies. The poten al benefits may outweigh the risks. Please
consult your doctor.
Lacta on : It is probably safe to use during breas eeding. Please consult your doctor.
Expert advice for Aldactone
The medicine can make you feel dizzy or sleepy. Avoid driving or opera ng machinery un l you know how the
medicine affects you.
Do not use supplements or salt subs tutes that are high in potasium. Consult your doctor if you develop any
muscle weakness, skin changes, red or black tarry stool. Avoid taking alcohol with this medica on as it may
cause dizziness, lightheadedness, and fain ng when you get up too quickly from a lying posi on.
Do not start or con nue spironolactone and consult your doctor:
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• If you have kidney disease, Addison’s disease (an adrenal gland disorder), liver disease, heart disease.
• If you have high levels of potassium in your blood (hyperkalemia).
• if you are also taking eplerenone or other potassium sparing diure cs.
• If you have an electrolyte imbalance (such as low levels of magnesium in your blood).
if you take an NSAID (nonst***idal an -inflammatory drug), cholestyramine, heparin, lithium, heart or blood
pressure medica on, potassium supplements, or another diure c.
Frequently asked ques on for Aldactone
Spironolactone
Q. Is spironolactone an ACE inhibitor/thiazide diure c/cor cost***id/ beta blocker?
No, spironolactone belongs to a class of medica ons called aldosterone receptor antagonists.
Q. Is spironolactone safe?
Spironolactone is safe, if used at prescribed doses for the prescribed dura on as advised by your doctor.
Q. Is spironolactone over the counter drug?
No, it is available as prescrip on drug.
Q. Is spironolactone used for weight control, birth control, for acne, loss of hair?
No, spironolactone is used in the treatment of failure of heart, resul ng in fluid build-up in lungs or other
body ssue (conges ve cardiac failure), chronic liver disease (hepa c cirrhosis) with accumula on of fluid in
peritoneum liver (ascites and edema), malignant ascites, nephro c syndrome, diagnosis and treatment of
primary aldosteronism.
Q. What is spironolactone/Dytor plus/Aldactone?
Spironolactone/Dytor plus/Aldactone belongs to a class of medica ons called aldosterone receptor
antagonists.
Q. Can spironolactone/Dytor plus/Aldactone cause cancer, hair loss, depression, insomnia, lower blood
pressure, cons pa on, increase estrogen, weight loss?
Spironolactone/Dytor plus/Aldactone can causes hair loss, increase estrogen cons pa on. Always consult
your doctor about possible side effects.
Q. Can i take spironolactone/Aldactone with ibuprofen/vitamins/ an bio cs/ phentermine/ me ormin
amoxicillin/ Adderall(amphetamine and dextroamphitamine/ Accutane (isotre noin)/ Benadryl
(diphenhydramine)/ Tylenol (acetaminophen)/ Lasix (furosemide)?
Indometacin may increase the diure c effect of spironolactone. Pa ents should follow doctors advice
regarding its use.
Q. Does spironolactone affect birth control?
No, Always consult your doctor about possible effects.
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Disclaimer
We provide only general informa on about medica ons which does not cover all direc ons, possible drug
integra ons, or precau ons. Informa on at the site cannot be used for self-treatment and self-diagnosis. Any
specific instruc ons for a par cular pa ent should be agreed with your health care adviser or doctor in charge
of the case. We disclaim reliability of this informa on and mistakes it could contain. We are not responsible
for any direct, indirect, special or other indirect damage as a result of any use of the informa on on this site
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