Is Weed Causing People to Leave Their Religion?Cannabis News
Religion and people using cannabis, read this https://cannabis.net/blog/opinion/the-great-exodus-from-organized-religion-is-cannabis-playing-a-key-role
Should We Put Social Justice and Cannabis Reform Together Anymore?Cannabis News
Is social justice and cannabis reform working, read this https://cannabis.net/blog/opinion/is-mixing-social-justice-with-marijuana-reform-doing-more-harm-than-good-right-now
Is Weed Causing People to Leave Their Religion?Cannabis News
Religion and people using cannabis, read this https://cannabis.net/blog/opinion/the-great-exodus-from-organized-religion-is-cannabis-playing-a-key-role
Should We Put Social Justice and Cannabis Reform Together Anymore?Cannabis News
Is social justice and cannabis reform working, read this https://cannabis.net/blog/opinion/is-mixing-social-justice-with-marijuana-reform-doing-more-harm-than-good-right-now
Do Marijuana Users Need More Drugs During Endoscopies and Colonoscopies?Cannabis News
Yes, they do on MAC scores, read this https://cannabis.net/blog/medical/whats-your-mac-score-why-cannabis-users-need-stronger-sedation-drugs-for-colonoscopies-and-endo
Can the Cannabis Industry Lead the Way on Water Issues in the World?Cannabis News
The marijuana industry to the rescue, read this https://cannabis.net/blog/opinion/how-the-cannabis-industrys-technology-could-help-solve-the-worlds-water-problems
The Conscious Cannabis Consumer Through the Lens of Psychologist Ken WilberCannabis News
Yes, he can look at weed, read this https://cannabis.net/blog/opinion/the-stages-of-the-conscious-cannabis-consumer-through-the-lens-of-psychologist-ken-wilber
Did Evolution Happen Due to Apes Eating Magic Mushrooms?Cannabis News
The Stoned Ape Theory of Evolution explained, read this https://cannabis.net/blog/opinion/did-apes-evolve-into-humans-because-they-ate-magic-mushrooms-the-stoned-ape-theory-of-evolution
The history of marijuana and racism, read this https://cannabis.net/blog/opinion/if-you-think-the-word-marijuana-is-racist-does-that-make-you-a-racist-too
New Political Ads Feature Weed Smoking Politicians?Cannabis News
Yes, we are smoking cannabis to get elected now, read this https://cannabis.net/blog/news/politicians-smoking-weed-to-get-elected-the-cool-new-trend-in-appealing-to-voters
Elon Musk Buying Twitter and the Woke Culture BacklashCannabis News
Musk on Twitter, read more https://cannabis.net/blog/opinion/ganja-theories-elon-musk-buying-twitter-signals-a-shift-in-the-laws-of-polarity-and-woke-cultur
Louisiana Legalizes Marijuana But Wants to Lock Kids Up for ItCannabis News
What is Louisiana doing, read this https://cannabis.net/blog/news/no-jail-time-for-weed-possession-in-louisiana-unless-you-are-a-kid-then-we-will-lock-you-up
Do Marijuana Users Need More Drugs During Endoscopies and Colonoscopies?Cannabis News
Yes, they do on MAC scores, read this https://cannabis.net/blog/medical/whats-your-mac-score-why-cannabis-users-need-stronger-sedation-drugs-for-colonoscopies-and-endo
Can the Cannabis Industry Lead the Way on Water Issues in the World?Cannabis News
The marijuana industry to the rescue, read this https://cannabis.net/blog/opinion/how-the-cannabis-industrys-technology-could-help-solve-the-worlds-water-problems
The Conscious Cannabis Consumer Through the Lens of Psychologist Ken WilberCannabis News
Yes, he can look at weed, read this https://cannabis.net/blog/opinion/the-stages-of-the-conscious-cannabis-consumer-through-the-lens-of-psychologist-ken-wilber
Did Evolution Happen Due to Apes Eating Magic Mushrooms?Cannabis News
The Stoned Ape Theory of Evolution explained, read this https://cannabis.net/blog/opinion/did-apes-evolve-into-humans-because-they-ate-magic-mushrooms-the-stoned-ape-theory-of-evolution
The history of marijuana and racism, read this https://cannabis.net/blog/opinion/if-you-think-the-word-marijuana-is-racist-does-that-make-you-a-racist-too
New Political Ads Feature Weed Smoking Politicians?Cannabis News
Yes, we are smoking cannabis to get elected now, read this https://cannabis.net/blog/news/politicians-smoking-weed-to-get-elected-the-cool-new-trend-in-appealing-to-voters
Elon Musk Buying Twitter and the Woke Culture BacklashCannabis News
Musk on Twitter, read more https://cannabis.net/blog/opinion/ganja-theories-elon-musk-buying-twitter-signals-a-shift-in-the-laws-of-polarity-and-woke-cultur
Louisiana Legalizes Marijuana But Wants to Lock Kids Up for ItCannabis News
What is Louisiana doing, read this https://cannabis.net/blog/news/no-jail-time-for-weed-possession-in-louisiana-unless-you-are-a-kid-then-we-will-lock-you-up
DISSERTATION on NEW DRUG DISCOVERY AND DEVELOPMENT STAGES OF DRUG DISCOVERYNEHA GUPTA
The process of drug discovery and development is a complex and multi-step endeavor aimed at bringing new pharmaceutical drugs to market. It begins with identifying and validating a biological target, such as a protein, gene, or RNA, that is associated with a disease. This step involves understanding the target's role in the disease and confirming that modulating it can have therapeutic effects. The next stage, hit identification, employs high-throughput screening (HTS) and other methods to find compounds that interact with the target. Computational techniques may also be used to identify potential hits from large compound libraries.
Following hit identification, the hits are optimized to improve their efficacy, selectivity, and pharmacokinetic properties, resulting in lead compounds. These leads undergo further refinement to enhance their potency, reduce toxicity, and improve drug-like characteristics, creating drug candidates suitable for preclinical testing. In the preclinical development phase, drug candidates are tested in vitro (in cell cultures) and in vivo (in animal models) to evaluate their safety, efficacy, pharmacokinetics, and pharmacodynamics. Toxicology studies are conducted to assess potential risks.
Before clinical trials can begin, an Investigational New Drug (IND) application must be submitted to regulatory authorities. This application includes data from preclinical studies and plans for clinical trials. Clinical development involves human trials in three phases: Phase I tests the drug's safety and dosage in a small group of healthy volunteers, Phase II assesses the drug's efficacy and side effects in a larger group of patients with the target disease, and Phase III confirms the drug's efficacy and monitors adverse reactions in a large population, often compared to existing treatments.
After successful clinical trials, a New Drug Application (NDA) is submitted to regulatory authorities for approval, including all data from preclinical and clinical studies, as well as proposed labeling and manufacturing information. Regulatory authorities then review the NDA to ensure the drug is safe, effective, and of high quality, potentially requiring additional studies. Finally, after a drug is approved and marketed, it undergoes post-marketing surveillance, which includes continuous monitoring for long-term safety and effectiveness, pharmacovigilance, and reporting of any adverse effects.
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
Local Advanced Lung Cancer: Artificial Intelligence, Synergetics, Complex Sys...Oleg Kshivets
Overall life span (LS) was 1671.7±1721.6 days and cumulative 5YS reached 62.4%, 10 years – 50.4%, 20 years – 44.6%. 94 LCP lived more than 5 years without cancer (LS=2958.6±1723.6 days), 22 – more than 10 years (LS=5571±1841.8 days). 67 LCP died because of LC (LS=471.9±344 days). AT significantly improved 5YS (68% vs. 53.7%) (P=0.028 by log-rank test). Cox modeling displayed that 5YS of LCP significantly depended on: N0-N12, T3-4, blood cell circuit, cell ratio factors (ratio between cancer cells-CC and blood cells subpopulations), LC cell dynamics, recalcification time, heparin tolerance, prothrombin index, protein, AT, procedure type (P=0.000-0.031). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and N0-12 (rank=1), thrombocytes/CC (rank=2), segmented neutrophils/CC (3), eosinophils/CC (4), erythrocytes/CC (5), healthy cells/CC (6), lymphocytes/CC (7), stick neutrophils/CC (8), leucocytes/CC (9), monocytes/CC (10). Correct prediction of 5YS was 100% by neural networks computing (error=0.000; area under ROC curve=1.0).
- Video recording of this lecture in English language: https://youtu.be/kqbnxVAZs-0
- Video recording of this lecture in Arabic language: https://youtu.be/SINlygW1Mpc
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.