Mapping of Images from Different Laboratory Imaging Environments into Central Imaging Archives

1. 1
Mapping of Images from Different Laboratory
Imaging Environments into Central Imaging
Archives
Md Mostafizur Rahman
mostafizur.rahman@med.uni-goettingen.de
3rd
ITIS Research Day, TU Braunschweig
08-07-2013

2. Multiple Sclerosis (MS)
2
Background Multiple Sclerosis MRI has become a major tool for the diagnosis of MS
SS 2013 – Medical Informatics – mostafizur.rahman
@med.uni-goettingen.de

3. Background: The Competence Network
Multiple Sclerosis (KKNMS)
Organization and geographical structure of the KKNMS (2012)
http://www.kkn-ms.de/
3
SS 2013 – Medical Informatics – mostafizur.rahman
@med.uni-goettingen.de

4. 4
B7.3 (DTI)
MS-BB MRI*
PatternMS/NMO
Cohort
Central
MRI-DB
20 study centers
Cohort Study
2 coordination offices
(Gö + Bo)
20 study centers
Cohort Study
2 coordination offices
(Gö + Bo)
standardized MRI
Gö
Subproject
PatternMS/NMO
Gö
Subproject
PatternMS/NMO
unstandardized MRI
post mortem MRIa
Bo+M+Mz
Subproject B7.3
Bo+M+Mz
Subproject B7.3 DTIa
Gö
Quality assurance
and biomarker
research
Gö
Quality assurance
and biomarker
research
Bo
Quality assurance
Bo
Quality assurance
M
Algorithm
validation
M
Algorithm
validation
Mz
Biomarker
research
Mz
Biomarker
research
Gö, Subproject
MS-Brain Bank
Gö, Subproject
MS-Brain Bank
KKNMS: Multiple Sub-Projects
Gö
Future research
Gö
Future research
Onetime
Regular
Regular
Multiple times
Regular
Multiple times
Data import
Data export
SS 2013 – Medical Informatics – mostafizur.rahman
@med.uni-goettingen.de

5. Research Project
• My first step is to analyze two imaging software solutions (XNAT, CHILI) and Identify the
limitations to handle the interface.
• Second step is to investigate the data lifecycle and workflow from the study center to the
research environment (and beyond).
– Segregate the curbs and pronounce the parameters to contribute data provenance transparency.
5
SS 2013 – Medical Informatics – mostafizur.rahman
@med.uni-goettingen.de

6. Göttingen
Coordinator Office
Bochum
Coordinator Office
Cohort Database Göttingen
CHILI
Study Center-1 Study Center -2 Study Center-3 Study Center-4 Study Center-5 Study Center-6 Study Center-20
Upload Via CHILI
Web Interface
CD Copy (Postal
Service)
Upload Via CHILI
Web Interface
KNMS
Subject
Identification Code
Patient Name
Patient ID
MRI Study
Image
CHILI Data hierarchy
6
SS 2013 – Medical Informatics – mostafizur.rahman
@med.uni-goettingen.de

7. 7
XNAT developed by the Neuroinformatics
Research Group at the Washington
University, St. Louis.
XNAT Image Data Hierarchy
XNAT database
Project
Patient ID
Patient Name
MRI Study
Image
Subject
Session
DICOM metadata
SS 2013 – Medical Informatics – mostafizur.rahman
@med.uni-goettingen.de

8. 888
Own
System
Own
System Own
System
Mainz Local
Research Institute
Munich Local
Research Institute
Bochum Local
Research Institute
Göttingen
Coordinator Office
Bochum
Coordinator Office
Cohort
Database
CHILI
XNAT
Study Center-1 Study Center -2 Study Center-3 Study Center-4 Study Center-5 Study Center-6 Study Center-20
Upload Via CHILI
Web Interface
Göttingen Local
Research Institute
Database
CD Copy (Postal
Service)
Upload Via CHILI
Web Interface
COHORT Project
Analyze Data
Structure and Data
Transmission
Analyze Data
Structure and Data
Transmission
SS 2013 – Medical Informatics – mostafizur.rahman@med.uni-goettingen.de

9. DICOM
9
DICOM object
identification
SS 2013 – Medical Informatics – mostafizur.rahman@med.uni-goettingen.de

10. XNAT Archive View
10
Patient ID= Session
SS 2013 – Medical Informatics – mostafizur.rahman@med.uni-goettingen.de

11. Göttingen
Coordinator Office
Bochum
Coordinator Office
Cohort Database Göttingen
CHILI
Study Center-1 Study Center -2 Study Center-3 Study Center-4 Study Center-5 Study Center-6 Study Center-
20
Upload Via CHILI
Web Interface
CD Copy (Postal
Service)
Upload Via CHILI
Web Interface
Investigate MRI Data Lifecycle
11
Pronounce the Parameters
•Media disruptions
•Current limitations
•Pitfalls
SS 2013 – Medical Informatics – mostafizur.rahman@med.uni-goettingen.de

12. 12
Evaluate the possibility of designing a system based on internationally
standardized IHE profiles/components that covers the complete data
lifecycle for MRI data in biomedical research projects.
Thesis
SS 2013 – Medical Informatics – mostafizur.rahman@med.uni-goettingen.de

13. 13
Prof. Otto Rienhoff
Director, Institute of Medical Informatics.
Karoline Buckow
KKNMS Research Project
Institute of Medical Informatics
SS 2013 – Medical Informatics – mostafizur.rahman@med.uni-goettingen.de
Thomas Franke
Head (Imaging Network Research Group)
Lika Svanadze Md Mostafizur Rahman
“Imaging Network” Research Group

14. Thank you
Further Questions and Advice
14