2. 1. What's the mechanism of action of each drug?
2. What the effect of the cytokine involved in each drug?
3. Give 1 medical use of each drug.
1 2
3. 1. Name the cell effected in this disorder.
2. Name 3 stains that you can use.
3. Give one genetic disease tat has the same mutation.
4. Give 5 triggers for activation of the cells effected.
4. This is a new drug inhibiting IL5
1. Which cells will be most affected?
2. Which antibody production most will be decreased ?
5. 1. Give 3 cytokines that activate this cell.
2. Give 3 clusters of differentiation expressed by these cells.
3. Give 2 types of cells killed by these cells.
6. 1. Give the names of the enzymes responsible for
production of reactive oxygen species ROS?
1. What enzyme responsible for the color of pus ?
2. What enzyme if effected in the disease above ?
7. Give the HLA affected in the following disorders:
1 2
3 4 5
8. 1. Identify the complement defect in the following disorders?
2. Name the features of C3 deficiency ?
1 2
3 4
9. 1. Which TLR most affected?
2. What is the main cytokine affected by this drug?
3. Give 3 approved FDA indications.
4. Which types of bacteria recognize the TLR inhibited
by this drug?